Nfla021142.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nephrotoma flavescens
Gene Symbol
-
Assembly
GCA_932525705.1
Location
CAKOBH010000712.1:332918-334855[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0016 0.29 13.4 0.8 1 23 180 202 180 202 0.99
2 10 0.42 75 5.8 3.2 1 19 208 226 208 230 0.74
3 10 2.8e-06 0.0005 22.1 0.5 2 23 237 258 236 258 0.96
4 10 5.7e-05 0.01 17.9 5.4 2 23 265 286 264 286 0.97
5 10 9.4e-05 0.017 17.3 1.3 2 23 292 314 291 314 0.95
6 10 0.00079 0.14 14.3 0.2 3 23 370 390 368 390 0.95
7 10 2.4e-05 0.0043 19.1 1.9 1 23 409 431 409 431 0.96
8 10 2.9e-06 0.00053 22.0 0.9 1 23 437 460 437 460 0.96
9 10 0.0056 1 11.7 0.3 1 23 468 490 468 490 0.96
10 10 0.0027 0.49 12.7 2.0 1 23 496 519 496 519 0.97

Sequence Information

Coding Sequence
ATGGCTAAAAATCGTAGTCACGTCTGTCGATACGGCCCCCTGTGTGATGCACGGAAAAGATTAATATTTGGTAAAATGGATATAAAAATTGACAAGACTTCATGTCGGGTTTGTTTAAAAAATGTTGGTGTAATACCCCTTTTTAGCGATTACGGGGACGGAGTACTTGCAGAAACAATAAGTTCACTCTTTAATATTTATATAAGCAGTGATACAAATTTACCAAATGCGGTGTGCGCAATATGCATGGAAAATATAAAAATTGCTATAAGTTCAAAAGAGGCAATCATGTGTGCGGAGAACATGTTAAATGACTTTCTGGAATCAAACAAGTCATTTAAAATTGAACAAGTGGAAAACTTGCCAATCAATGAATATGATATTCCTGGCCGTTATCTACCTAAATTAGATAATTTGGATGTTTTGGAACATTTAAAAATTGAACATAAGGATGACAAAATTTTAGATAGTTCAGAAGAGTACGAAGCGATTAAATGTTATGAAGATATATCGTCAGAATTAATTAGTTCTCAATTGTATGAATGTCTTAAATGTGAAGTCAAAACAGATACCTATAAACAATTGATCCTACATATGCGATCTCATTCTGACATTACCATGTATGAATGTGAAACTTGCGGAAAAGAATTCAAATGCCGATCAATATATGTTAAACATGCATTTCGTCACTATGACAATAGGCCATGCAAATGTGACGAATGTGGTAAAGCCTTTAAGGGTCCTCGGGATCTTGCCCAGCATCTTTTAACCCACCAAACGGCGAGAATACTTCCATGCCAGCATTGTGGTAAAACATTTTGTCATATGAAAGGACTAAAAGCACACTTACTAACCCACAATGAAAAAACTAAAGTATGTGAGATTTGTGGTAAACTATTTAAACACTCAACATTTTTAAAAACTCATATTGGAACAGTGCATGGTTTACGTACTGGACGCAGTGGAAATAAATACGCAAATTCACGGCGGCAAGTTACTTGTGAATTTTGCGGGAAATTAATGGCTTACACTAATCTGAAGAAGCATATTGAAGCTCAACATAGTGACTCAATAGCCGTTAAACCAGATCCCGGCAACGCGATTATTTGCTTATATTGCAATAAAAGTTTTCTCACCAATGCCGGTTTAAAGATGCATATGCAAGCGCATATTAATACAAAAAAAAACCCGTTGGATGTTAAAACGAAGGAAAAATATTTAAAATATAAATGTGATGAGTGTGATAAATGCTTTGTGAGTGCTGTATTTTTGAGAAATCATAAAATCTTACACTCAGGCATTAAAGAGCATGTATGTCCGTATTGCGGAAAAGAATTTGCATTTAAAATGTATTTAGAGCGCCATGTACGTTTACTGCACGATACAACTAATCCAAGAAATTTTAATTGCCATATATGTGGTAAAGTTTCTGCATTTGGAGCAGCTAGAAAAGCGCACATGCTTTCACATACCCGAGAAACACCGTTCGAATGTAAATTTTGTAGTTCGAAATTCGTGTATGCCAAATCACTTCGAATTCACATCAAGAATAAACATAAAACAGAAATTAATGAAAATAGTGAAAAAACATAA
Protein Sequence
MAKNRSHVCRYGPLCDARKRLIFGKMDIKIDKTSCRVCLKNVGVIPLFSDYGDGVLAETISSLFNIYISSDTNLPNAVCAICMENIKIAISSKEAIMCAENMLNDFLESNKSFKIEQVENLPINEYDIPGRYLPKLDNLDVLEHLKIEHKDDKILDSSEEYEAIKCYEDISSELISSQLYECLKCEVKTDTYKQLILHMRSHSDITMYECETCGKEFKCRSIYVKHAFRHYDNRPCKCDECGKAFKGPRDLAQHLLTHQTARILPCQHCGKTFCHMKGLKAHLLTHNEKTKVCEICGKLFKHSTFLKTHIGTVHGLRTGRSGNKYANSRRQVTCEFCGKLMAYTNLKKHIEAQHSDSIAVKPDPGNAIICLYCNKSFLTNAGLKMHMQAHINTKKNPLDVKTKEKYLKYKCDECDKCFVSAVFLRNHKILHSGIKEHVCPYCGKEFAFKMYLERHVRLLHDTTNPRNFNCHICGKVSAFGAARKAHMLSHTRETPFECKFCSSKFVYAKSLRIHIKNKHKTEINENSEKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01053735;
90% Identity
iTF_01052582;
80% Identity
-