Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: RREB1
Assembly: GCA_947310385.1
Location: OX371225.1:9541051-9546312[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0012 0.26 13.9 2.1 1 23 118 140 118 140 0.97

2 14 0.00058 0.13 14.9 5.8 1 23 148 170 148 170 0.99

3 14 5 1.1e+03 2.5 0.5 1 23 288 312 288 312 0.80

4 14 0.02 4.4 10.0 4.2 2 22 318 338 318 338 0.94

5 14 3.4 7.5e+02 3.0 0.6 1 11 383 393 383 403 0.85

6 14 0.029 6.5 9.5 0.1 1 23 540 562 540 562 0.97

7 14 3.9e-05 0.0087 18.5 0.9 1 23 571 593 571 593 0.99

8 14 0.001 0.23 14.1 2.0 1 23 599 622 599 622 0.97

9 14 0.0012 0.26 13.9 2.1 1 23 960 983 960 983 0.95

10 14 2.5e-05 0.0056 19.1 0.4 2 23 1309 1330 1308 1330 0.98

11 14 0.18 40 7.0 6.3 1 23 1336 1359 1336 1359 0.97

12 14 3.4 7.6e+02 3.0 5.8 1 23 1437 1460 1437 1460 0.95

13 14 0.01 2.3 10.9 0.5 3 23 1516 1536 1514 1536 0.96

14 14 0.0055 1.2 11.8 5.1 1 23 1542 1564 1542 1564 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0012	0.26	13.9	2.1	1	23	118	140	118	140	0.97
2	14	0.00058	0.13	14.9	5.8	1	23	148	170	148	170	0.99
3	14	5	1.1e+03	2.5	0.5	1	23	288	312	288	312	0.80
4	14	0.02	4.4	10.0	4.2	2	22	318	338	318	338	0.94
5	14	3.4	7.5e+02	3.0	0.6	1	11	383	393	383	403	0.85
6	14	0.029	6.5	9.5	0.1	1	23	540	562	540	562	0.97
7	14	3.9e-05	0.0087	18.5	0.9	1	23	571	593	571	593	0.99
8	14	0.001	0.23	14.1	2.0	1	23	599	622	599	622	0.97
9	14	0.0012	0.26	13.9	2.1	1	23	960	983	960	983	0.95
10	14	2.5e-05	0.0056	19.1	0.4	2	23	1309	1330	1308	1330	0.98
11	14	0.18	40	7.0	6.3	1	23	1336	1359	1336	1359	0.97
12	14	3.4	7.6e+02	3.0	5.8	1	23	1437	1460	1437	1460	0.95
13	14	0.01	2.3	10.9	0.5	3	23	1516	1536	1514	1536	0.96
14	14	0.0055	1.2	11.8	5.1	1	23	1542	1564	1542	1564	0.99

Sequence Information

Coding Sequence: ATGGACCGTCGCCTATCAACCAATTCCGAATCATCAATCGAACCGATGGACATAAGTGTTTCGAATAAAACCACCAGCTCAGACGGAAATAATACATCAAGTGCAATGGCAATAAGTAAAATAACCGAATCGAATCATAGCGATACGGACAATGGTGGCATTGAATCGGAGGAAAACGATGAAAATATTGTGCGACGCGAAAATCTTCGTTTACACAATAGCCATATTGATACGAAAATGCTACGGAAAAAATTTCGCCTCATGAATAATAATAACAATAATAGTAATTGTAATAATAACACCGCGATCGATAAAAATCTCAGTATTGAATTACATGAAAATTTGGAAAATTTTCAATGTCATATTTGCTCAAAACATTTAACTTCGTCGATTGCACTGGTGCGCCACCTTCAAGCACATACCATAGATTCTGAAAGCCCATATAAATGTAATTTATGTCATATTTCATTCACGACCCTGGCTAATATGCATCGACATACAAAAAGTCATCAGCTcgataatgacaagaataacaataataatgatgatgaggacgatgaagattatcttagtaacgataatgatgagtatgaacgtggtgtctcgtccgatgtttcgtcaggtaacgaaagccgcgacagtgttaatgataatatacgtaataataataataataataataataacaataatgctaataataattattcgattggtaaacgaaaaatttcgaatgacgcccatgacgacttaataagcctgaagcgtaaaaattacaataataataaCCTTATCAATAAAAATTTTATAAATCAAACAAGTCAAATGCTGGTGGAAGCGCAACAGCACCAACAACAAAAATTTTGTTGTCCCGTCTGCGATCGTAATGATTTTATAAGCATGCTCGCACTAGAAAATCACATGGATAAAGAGCACCCTAGTATTCAAGCACGTTGCCGTCACTGTGACATTGTATTCAAAAGTCATAAAGCATTAAATGCCCACCGTTGCACAAAATCGACAAACCAAAGCATAACTCAGGGATTTAAAGATTTAACGTTCATCGATTTTTCTAGCGAGAAGTTTCCGATAATTGCAAAATCCGTATGTGAGCAAACAATTCGAACGCCAATAACTTCGCAAAAATATGAATGTCCAAAATGTTATCGGGCGTTCCCGTGTTCGACCGCGGTCGATATTCATGTACGGGAATGCGGTGGGGCGAATGATTCAGCAATTGTTCAAGACTTTTCGATGCGTACAAATAAACGCACCGACAGCAGTGACATCTCGGATGATGATGAATGCAAGCGTGATGACTTTTTTGCTAATCTAGACCTACAAAATAAAACATCAAATACATTTAATACATCGAACAATAGTTCACCGCGATCGACTGTTTCGTCTGATATTATGAGAACGCCCTCTCTACATCACTCAATTGACTCTAAAGATTTGGCTGATATTCAATCGATAATTAATGTAACGTCGTCCGGAGGATTATTGCGACATTTAGACAAACCGTTAAAAGATCATTTAGGCCAGCCGAAAGAGATTGAGGAAGAGGCACAAGACGTCTTTACCGCTGAATTTCGTAAAATGAAGTTGCGTGGAGAATTTCCTTGCAAATTGTGTACAGCAATTTTTCCAAATTTACGCGCTCTCAAAGGCCATAACCGGGTACATTTATCGGCGGCTGGTGCTGGACCGTACCGATGCAACATGTGCCCGTACTCAATACATGATAAAGCGGCTTTAATACGTCATATGAGAACACATAATGGTGATCGCCCATATGAATGTGCAGTTTGTAATTACGCGTTTACAACGAAAGCTAATTGTGAACGGCATTTACGCAATCGTCATGCTAAGACGACGCGAGAAGAAGTTAAACGTGCTATTATCTATCATCCATCCGAGGATTCGTCGGCCGACGAACACCATCATAGCAAAAAAATGACAATGTTTAGCTCGCCTGATTTTAATGAAGACGAGGACCGGATTCCTAAAGATCGTAGCACTCCAGTCTCATCGAGACTTCAAGATTTATTATTGCCTGACAACCATCACCAACGACTGGCTGCCTCGCTTTCACCGTCGCCATTAAAAATACAAGTAAAAAGTTTGGAGAAATTAATTCATCCAGAAATCGTAAAAAGTGAGGTGGAAGATGATATTGAGGAGAAGAAAGTGATTGAAGCAAATAATGATGACACAAATCGATCAGAAGATGAAGAAGAAGAGGAGGAAGCTAATGAAGAAACAAAGCCGATTGATCTCTCAATGGACGCGCTAGACTTAAGCAAAAAAACTAAATTCGATGAAAATAAATCATTGAATTTGCTCAACAACAATAATAACGATGAGCTATCATTCTTCGAAAAGAATAAGCAACTGTTTATGGCACAACAACAGTTTTTAAACGAAACCCTTCCAAAAATCGACCCCTCGCACTACCTTCAATTATCTCACTTGTACCGAAATTTTATGTTTCCACCACCTGGTTTTCCCCCATTTTTAATGCAAAATCCGTTATTGCAACCACCAAATCTCGGTGAAATGCAAGATATGATGCGCGGCCAAATGTCTGGAGGAAATTTGATATTTAACCAACAAACATCTTCATCACCAACGCCACCACCAATTTCAATCAAATCACAACCACATGATGATTCTCCGCCGAAAAGTAGTAGTATGACTGAATCGCACAAGTACAGTCCAATCACTACACCGACTAATAGCAACAATAATGCGCTACAAAACAATAGTATGCAGGCACAAAATAATCAAATGTCGAACGGGCCTGTCAAAATGGTTATTAAAAATGGTGTTTTGATGCCAAAACAGAAACAACGAAGATATCGCACCGAACGTCCATTTGCATGTGAGCATTGTAGTGCAAGATTTACGCTACGGTCAAATATGGAACGGCATATTAAACAACAACATCCACAATTTTGGGCACAACGTCAGCGAAGTGGCCATAACCTACTTCGTCGTGGTAGTGGACCTCCACCACCACCTTCTCCTCAACAACAACAACAACAGCAGCAGCAACCGTCACAATCGCAACCACCTCCACAACAATCCATGAATCACATGATGCCACAAAATGTACCGCAATTACCAAATCAACCGAATTTTACATCGATATCCGATCAAGTAAAATATGCTATTCTCGCTCAACAACTCAAATATAATAAAGAAAGTAGTAATAAATTGGGGATGCCATCATCGCTGGTGCAATCTCTAAATAACAACAGCCACATGCTTCCGAATAATAATAATAATAATAACAACAACAACAACAACATAAAAAATTCGATGTATGAAAATCAAAATAATCAAACTATTAACAATAACGACGAGGAAGATGAACCTCAATTAGTTATTGACGAAGACTCACAACCAGAAGACTTATCCAAATTGGAATCACCAAAGAATGCTGTCACACCAAATAATGATTTACACCAGAACAATGTAATTGAGGCGAAAAAAATTGCCGATAATATATTGGAACAAGCCAAAAAAGCGTCATCGAGTATGAACGCCACCACTGCTGCAATTCCATCGAATACCAATATAAATCCGGAAACTGCTAAAGATTTTGATTTAAAAATTTCACCAAATTTAATTGCCAAATCGGAAAATGTACCAATAAACTATAATTTGTATCAGGGGAAAGATAATCATCGTGAAGAGGGTGATTTGGCATCCGTGTCCCGATTAGTGGATAACGCGTTCGGTAATTTTTTTGGAAATAACGAAATTAACACCCCAATGGAGCATAGCGATGAAGATGGCTTAGTAGCATCGGGTAGTGCGTCCGAAAGTAATAATTCGGGGCCAGAAGATCACACGTCTGCCATACCGATCGAACCACAAAAGAAAAAATCTGCTTACAGTTTAGCACCAAATCGTGTTAAATGTCCATACTGTCAACGGTCGTTTCCATGGTCTAGCTCCTTGCGGCGACATATCCTAACGCACACCGGACAAAAACCATTTAAATGTTCACACTGTCCTTTGCTATTTACAACAAAATCAAATTGTGATCGCCATTTACTGCGCAAACATGGAAACGTCGAATCAGCCATGTCAGTCGCTGTGCCAATCGATGAAAATATTCCAGAGCCGATAATCAAAAAAGAACCAAAAGAGTATCCTGAAAATGAACCGAATAAATCACCCAAAATGACTGCACCAATAATTCCGCCAACATTCATTCCAAATTTAGTTTTAAGCCTAAAAACTGAACTTATGAATAGTAATAACGCATCAAACATTCCAGTTAGTACTGAACTTCCATACAAGTGTCATTTATGTGATGGTTCATTTTCGGAACGAATGCAGTGTTTAGAACATATTCGGCATTCGCATGCGCAAGAGTTTGCATTACTATTGGCCAAAGGCGCGATTGATGCAGATCCAGAAAGTAATGCGAGTGCACAGCAGCAACTGCAGCATAGCAGCGAGAATAATATGGATGAGGAGAATAAAGATGGAAAGGGGAAATATCCTGATTATGCTAATCGAAAGGTCATTTGTGCATTCTGTGTTCGACGATTTTGGTCAACCGAAGATCTAAGACGCCATATGCGAACCCATTCTGGGGAACGTCCATTCCAGTGTGACATTTGTCTACGTAAATTTACGTTAAAACACAGTATGTTGCGGCACCAGAAAAAGCATAGTGCGCACAATAACAATCAACAGCAAAATAATAGCGCATCAGACATGTCGGATGAAGAACCGACAACAACAATGATTCCAAATAAATTACTCAACATTCCGGATTTAATACCAAAAGACTTAGCACACACGGCCCAATGGAAGCTGAGCCAATTACAAGCAAAACTATTTGGTCAACATCATAACGAAAGTGCAGGCACAAATAATAACAATCATCATCATCAAGCTCCATCACCACCATCATTCCTTATTTCACCATTTCTACAGCTTCAGCAGCGTTTTGCTAGTTTAGCCCAAGCTGGACTCGATGGCCACTCAAAAGATCATCACGATCAAGATGAATCGGATCTAATCGGAAATCTACTCGGTATAAGCGATCAAGGTATTTTAAATCGGGTTTTGGTATCGTCAGCCGATGAAGCTGCTAAATTATTAGGAGTTGAAAAATAA
Protein Sequence: MDRRLSTNSESSIEPMDISVSNKTTSSDGNNTSSAMAISKITESNHSDTDNGGIESEENDENIVRRENLRLHNSHIDTKMLRKKFRLMNNNNNNSNCNNNTAIDKNLSIELHENLENFQCHICSKHLTSSIALVRHLQAHTIDSESPYKCNLCHISFTTLANMHRHTKSHQLDNDKNNNNNDDEDDEDYLSNDNDEYERGVSSDVSSGNESRDSVNDNIRNNNNNNNNNNNANNNYSIGKRKISNDAHDDLISLKRKNYNNNNLINKNFINQTSQMLVEAQQHQQQKFCCPVCDRNDFISMLALENHMDKEHPSIQARCRHCDIVFKSHKALNAHRCTKSTNQSITQGFKDLTFIDFSSEKFPIIAKSVCEQTIRTPITSQKYECPKCYRAFPCSTAVDIHVRECGGANDSAIVQDFSMRTNKRTDSSDISDDDECKRDDFFANLDLQNKTSNTFNTSNNSSPRSTVSSDIMRTPSLHHSIDSKDLADIQSIINVTSSGGLLRHLDKPLKDHLGQPKEIEEEAQDVFTAEFRKMKLRGEFPCKLCTAIFPNLRALKGHNRVHLSAAGAGPYRCNMCPYSIHDKAALIRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHAKTTREEVKRAIIYHPSEDSSADEHHHSKKMTMFSSPDFNEDEDRIPKDRSTPVSSRLQDLLLPDNHHQRLAASLSPSPLKIQVKSLEKLIHPEIVKSEVEDDIEEKKVIEANNDDTNRSEDEEEEEEANEETKPIDLSMDALDLSKKTKFDENKSLNLLNNNNNDELSFFEKNKQLFMAQQQFLNETLPKIDPSHYLQLSHLYRNFMFPPPGFPPFLMQNPLLQPPNLGEMQDMMRGQMSGGNLIFNQQTSSSPTPPPISIKSQPHDDSPPKSSSMTESHKYSPITTPTNSNNNALQNNSMQAQNNQMSNGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQFWAQRQRSGHNLLRRGSGPPPPPSPQQQQQQQQQPSQSQPPPQQSMNHMMPQNVPQLPNQPNFTSISDQVKYAILAQQLKYNKESSNKLGMPSSLVQSLNNNSHMLPNNNNNNNNNNNNIKNSMYENQNNQTINNNDEEDEPQLVIDEDSQPEDLSKLESPKNAVTPNNDLHQNNVIEAKKIADNILEQAKKASSSMNATTAAIPSNTNINPETAKDFDLKISPNLIAKSENVPINYNLYQGKDNHREEGDLASVSRLVDNAFGNFFGNNEINTPMEHSDEDGLVASGSASESNNSGPEDHTSAIPIEPQKKKSAYSLAPNRVKCPYCQRSFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVAVPIDENIPEPIIKKEPKEYPENEPNKSPKMTAPIIPPTFIPNLVLSLKTELMNSNNASNIPVSTELPYKCHLCDGSFSERMQCLEHIRHSHAQEFALLLAKGAIDADPESNASAQQQLQHSSENNMDEENKDGKGKYPDYANRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHQKKHSAHNNNQQQNNSASDMSDEEPTTTMIPNKLLNIPDLIPKDLAHTAQWKLSQLQAKLFGQHHNESAGTNNNNHHHQAPSPPSFLISPFLQLQQRFASLAQAGLDGHSKDHHDQDESDLIGNLLGISDQGILNRVLVSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01455207;
90% Identity: iTF_01054760;
80% Identity: -