Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: -
Assembly: GCA_947310385.1
Location: OX371223.1:21477594-21479765[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00015 0.032 16.8 0.8 1 23 156 178 156 178 0.98

2 16 0.026 5.7 9.7 1.5 1 23 184 206 184 206 0.98

3 16 5.8 1.3e+03 2.3 0.0 2 12 211 221 210 224 0.85

4 16 0.0037 0.83 12.3 0.2 2 23 279 300 278 300 0.96

5 16 0.00015 0.033 16.7 1.4 1 23 322 346 322 346 0.98

6 16 0.011 2.4 10.9 1.8 2 23 353 374 352 374 0.89

7 16 0.003 0.66 12.6 1.8 1 20 380 399 380 402 0.95

8 16 0.0046 1 12.0 0.4 2 23 407 428 406 428 0.96

9 16 0.00015 0.034 16.7 0.1 2 23 474 495 473 495 0.96

10 16 4.5 1e+03 2.6 0.2 1 9 501 509 501 523 0.79

11 16 8.5e-06 0.0019 20.6 1.8 1 23 529 551 529 551 0.98

12 16 0.00017 0.039 16.5 0.9 3 23 559 579 557 579 0.95

13 16 0.072 16 8.3 0.1 5 23 591 610 585 610 0.84

14 16 0.03 6.6 9.5 0.6 1 23 616 638 616 638 0.94

15 16 0.00027 0.059 15.9 5.6 1 23 644 666 644 666 0.99

16 16 0.00017 0.038 16.5 0.1 1 21 672 692 672 693 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00015	0.032	16.8	0.8	1	23	156	178	156	178	0.98
2	16	0.026	5.7	9.7	1.5	1	23	184	206	184	206	0.98
3	16	5.8	1.3e+03	2.3	0.0	2	12	211	221	210	224	0.85
4	16	0.0037	0.83	12.3	0.2	2	23	279	300	278	300	0.96
5	16	0.00015	0.033	16.7	1.4	1	23	322	346	322	346	0.98
6	16	0.011	2.4	10.9	1.8	2	23	353	374	352	374	0.89
7	16	0.003	0.66	12.6	1.8	1	20	380	399	380	402	0.95
8	16	0.0046	1	12.0	0.4	2	23	407	428	406	428	0.96
9	16	0.00015	0.034	16.7	0.1	2	23	474	495	473	495	0.96
10	16	4.5	1e+03	2.6	0.2	1	9	501	509	501	523	0.79
11	16	8.5e-06	0.0019	20.6	1.8	1	23	529	551	529	551	0.98
12	16	0.00017	0.039	16.5	0.9	3	23	559	579	557	579	0.95
13	16	0.072	16	8.3	0.1	5	23	591	610	585	610	0.84
14	16	0.03	6.6	9.5	0.6	1	23	616	638	616	638	0.94
15	16	0.00027	0.059	15.9	5.6	1	23	644	666	644	666	0.99
16	16	0.00017	0.038	16.5	0.1	1	21	672	692	672	693	0.96

Sequence Information

Coding Sequence: ATGCTTTATGCAATAGATAGCACATGCCGCAGTTGTTTAAAAGACACAGCGACAGATATTGCCGTGTCACTATTCGAATATTGTTGTGTAGATTCGAATAATTTTCTTATTTCCGATCTCTTTGAAATATTTACAAATGTAGACATTAATAAGGATGATAATCTTCCGACTCAAATATGTGAAAGTTGTCTGGATGAGTTAATATCGGTGTACCGGTTCCAAAAAAAATGCCAACAATCTGATGAGATCTTGAAAGCAGACACAACGGATTGTGATTCCGCTGGCGATGTAGAGTTTAAAGAGGAGTACCTAAACGATGCTGAGGCATGCACTCAAGTTGAAATGGAACAATTAAATGAAACCATGGTGAATGAGCAGAATTACAATGCCGATGAGTCTAATAACTCCTGTACATCAATTGCGGACTATTCGATACACAAAGTGATACGTAATCCTAAACACTGGTACAATTGCGATTACTGTGATAAAGGATTTCCGCGAAAAATTATGAAATTAAACCATCAACGCATTCACACTACAGACCATCCATTCAAGTGTTCCGTATGCCAAGTATCCAAAATGACAAAATCGTCTCTCGTAAAACACTTGACAACGCATATAAATAAATTGAGATGTGATGTTTGTGATCTCAATTTTGAAAGTTACAGGTTAGAGGTGTTACACTTTACAAGGAAAGAAAACTGCCCAAAACACCAAGTTGCCCGTAGTGATTTTTCTCAAAATACAGTATTGGATACAGAAGAGATAATGGCCCGGGAGCAAATCAATACAATTCAATCGACTAGCAAGTCAAGAAAAAAGAATTTACAAGTGCAGTGTAAAATTTGTGCGATCGAATGTTCAACGCCGGCCGAACTTCGACAACATTTAGAACTTCACAACAATACCGAACTAGAAACTAATCCATCTAGCCCTAAAACAAAAGAGGGCAATGTTACCAATTACAAATGTTCCGAGTCAAAGTGCGGAAAAATATTTACGAGCTCAATATCATATCGTGAACACAAGAAAATCCATAATCCGGAGAGTGCCGTGAAATGCGATTACTGCGACAAAATGTTCTCGTCCAAAGCTAGGCGAGAACCCCATCATCGCGTACATCGTGGTGAACGACCTTACAAATGTAGTGTATGTCCAGAAGCACGAACCACGAAATCAACGTTGCTTAAACATTTGCTGTGCCATGCCCGATCCCTAAAATGTAAACCGTGTGGGATTAATTTTGAATCATCTCGGTCGTATGTTTCCCACATGAAAATACACGAAGAAGATCCAAATTATGAACCGAACAATGATTCTGAACCCGAAGAAGAACTAGATGAAAATCAACGGAAATTACGAGAACATATCGAGGAAATACGTTCGACATCACTGGCCCAGAAACGAAACATAAACACAAAATGTACGATTTGCTATCGAGAATTCGCCACACCGAGTGAATTAAAATTGCACGCGGAAATACATCAAGATGTCGGTGATTATTTGTGCACGATATGCGGAAAAATTTCGCTGACGAAAGCAGGACATCGTGAACATCTGGCCTTACACGAATCTAGTGGCACATTCCAATGTGAATATTGTAATGAGGTATTCTCTTCAAACCATCGATTGAAGGCTCATATTCTGCAACACACCGGTGAACAACCACATCTCTGCAAAGTTTGCGGTAAATCATTTTCCACTGCGATCGTTCTGCGTGTACACAATCGTCTGCATACCGGTGAAAAGCCATTTAAATGTATCGTTGACGGGTGTGCGGCTGCATTTCGCACCGCAAGCAAATTAAATCGTCATCGTATTGCGACACATACGAATATACGGCCATTTGAATGTATTATTTGTTCGAAAAAGTTCGCATTCTCTGACGAATATAAATCGCACTCTTTAATACATTCAACTGATACGCCGTATGAATGTGGTGTTTGCGGCAAAGGATTTCACAAAAACCACTGCCTTAAATCTCATTTACGGATACATACGGGCGAAAAACCATACAAATGTGAAGTATGTGGTAAAGCATATCGATTGCGGAACGCTCTAACCAGTCACTTGAAAGCATGTAAAGTTAACGAAGATGAAGCGGAAAGCAATTAA
Protein Sequence: MLYAIDSTCRSCLKDTATDIAVSLFEYCCVDSNNFLISDLFEIFTNVDINKDDNLPTQICESCLDELISVYRFQKKCQQSDEILKADTTDCDSAGDVEFKEEYLNDAEACTQVEMEQLNETMVNEQNYNADESNNSCTSIADYSIHKVIRNPKHWYNCDYCDKGFPRKIMKLNHQRIHTTDHPFKCSVCQVSKMTKSSLVKHLTTHINKLRCDVCDLNFESYRLEVLHFTRKENCPKHQVARSDFSQNTVLDTEEIMAREQINTIQSTSKSRKKNLQVQCKICAIECSTPAELRQHLELHNNTELETNPSSPKTKEGNVTNYKCSESKCGKIFTSSISYREHKKIHNPESAVKCDYCDKMFSSKARREPHHRVHRGERPYKCSVCPEARTTKSTLLKHLLCHARSLKCKPCGINFESSRSYVSHMKIHEEDPNYEPNNDSEPEEELDENQRKLREHIEEIRSTSLAQKRNINTKCTICYREFATPSELKLHAEIHQDVGDYLCTICGKISLTKAGHREHLALHESSGTFQCEYCNEVFSSNHRLKAHILQHTGEQPHLCKVCGKSFSTAIVLRVHNRLHTGEKPFKCIVDGCAAAFRTASKLNRHRIATHTNIRPFECIICSKKFAFSDEYKSHSLIHSTDTPYECGVCGKGFHKNHCLKSHLRIHTGEKPYKCEVCGKAYRLRNALTSHLKACKVNEDEAESN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01053675; iTF_01054608;
90% Identity: iTF_01053675;
80% Identity: -