Nscu030103.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nephrocerus scutellatus
Gene Symbol
KLHL5
Assembly
GCA_947095585.1
Location
OX352761.1:7583470-7588647[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 4.4e-23 2.5e-20 73.8 0.0 23 109 42 127 35 128 0.92
2 2 0.36 2.1e+02 3.3 0.1 80 104 142 166 136 169 0.87

Sequence Information

Coding Sequence
ATGAGTTCAGTTTTTAAATCAAAGCGATTGGAACTCATTGTGGGAAATTCGCCACAAACTGGTCACAGAGATTTGGGCGTTAAGGAAAAGGAGGAGAAAAGTGGAGATGTCTATGAGCTTGTAGTACCAGCACATCGACTAGTGTTGGCCGCATCGAGTGCATATTTCTCCGCAATGTTTACAGGATCACTGCGCGAAACCAAAGAGGAAGAAGTCACTTTGGGTGAAGTTCACGGTGATGCTCTACAAATTCTAGTGCAATACTGTTACACAGGCTTCATAGAACTACGCGAAGACAGTGTTGAGACCTTGCTAGCTACAGCGTGCCTTCTTCAGCTGAACGCCGTTGTGACGGCTTGTTGTAATTTCCTTGCCCGGCAACTGCATCCCTCAAACTGCTTGGGTTTTGCTTTCTTTGCCGAGCAGCAAAGTTGTAATACCCTATTGAAGTTAGCCAAATCCTATACCTGCCAAAATTTCATGCAAGTTTGCAAAAATCAGGAATTTTTTCAATTGAATGCCGAACAATTGGGAAAACTGCTCTCGAGTGATGATCTCAATGTTCCCTCGGAACAGGATGTCTTCCACAGTCTCATGTCATGGATACAGCATGATTCACAAAATCGTGAGAAATGCATTCCAGAATTGTTAGCTCTAATACGATTGCCGTTGCTGCAGCCATCGTTTATTGCCGATCATGTGGAATCTGTGTGTGGTTCCAGTGATTGTCAGCAACTCGTTATGGAAGCCCTCAAATGGCATTTGCTGCCCGAACGACGATCTCTAATCTCTACAGAACGAACGAAACCGCGAAAATCAACAGTTGGCCGCCTCTTGGCCGTTGGCGGTATGGACTCACACAAAGGTGCCATCAACATCGAAAGTTATTGTCCGCGTCTCGACAAATGGACCGCGTGGAAAAATATGTCAGGACGCCGGCTGCAATTTGGTGTCGCAGTTATGGATGACAAGTTGATTATTGTCGGCGGACGTGATGGTCTGAAAACGTTGAATACTGTTGAAAGCTTAGATTTAAATACTATGACCTGGACACCTCTCAACACAATGGGAACACATAGACATGGCCTAGGAGTTGCTATACTCGAAGGGCCATTGTATGCTGTTGGTGGACATGATGGTTGGAGCTATTTGAATACAGTCGAAAGATGGGATCCACTTGCACGCACGTGGCACTATGTAGCACCAATGTCGCAAATGCGATCTACAGCTGGAGTTACGGTTCTCGGTGGTCGGCTCTACGTTGTTGGTGGTCGTGATGGTTCAGTGTGTCATCGGTCAGTTGAATGTTACGATCCGCATACGAACAAATGGACTCTGAGGGCTCCTATGAACAAGCGACGTGGTGGAGTTGGGGTAGCTGTCGCCAATGGATATCTCTACGCACTTGGAGGTCACGACTGTCCTGCCAGTAATCCATCGGTGTGTCGGACGGACACAGTTGAACGATATGATTCAGGAACAGACACCTGGACTTTGATTTGTTCATTAAGCATCGGTCGCGATGCTATTGGTTGTGCCCTACTGGGAGATCGTCTTGTCGCTGTTGGCGGATTCGATGGTAATCAATATCTGAAGACTGTCGAAGAGTATGATCCAGAAACAAATGAATGGTCGCAAGTTGCCCCGCTGACGTTCAATCGAGCTGGCGCCTGTGTGGTCACAATCCCGAATATTATTCCATCGACACCGCCACTTGCTAGTTCAACGAAAAAATGGAAACCCGTTAGATTAAATCCCTACTGCTACAGGCGAACTGTAGAATTTGTCGATTACTATAATCTTTAA
Protein Sequence
MSSVFKSKRLELIVGNSPQTGHRDLGVKEKEEKSGDVYELVVPAHRLVLAASSAYFSAMFTGSLRETKEEEVTLGEVHGDALQILVQYCYTGFIELREDSVETLLATACLLQLNAVVTACCNFLARQLHPSNCLGFAFFAEQQSCNTLLKLAKSYTCQNFMQVCKNQEFFQLNAEQLGKLLSSDDLNVPSEQDVFHSLMSWIQHDSQNREKCIPELLALIRLPLLQPSFIADHVESVCGSSDCQQLVMEALKWHLLPERRSLISTERTKPRKSTVGRLLAVGGMDSHKGAINIESYCPRLDKWTAWKNMSGRRLQFGVAVMDDKLIIVGGRDGLKTLNTVESLDLNTMTWTPLNTMGTHRHGLGVAILEGPLYAVGGHDGWSYLNTVERWDPLARTWHYVAPMSQMRSTAGVTVLGGRLYVVGGRDGSVCHRSVECYDPHTNKWTLRAPMNKRRGGVGVAVANGYLYALGGHDCPASNPSVCRTDTVERYDSGTDTWTLICSLSIGRDAIGCALLGDRLVAVGGFDGNQYLKTVEEYDPETNEWSQVAPLTFNRAGACVVTIPNIIPSTPPLASSTKKWKPVRLNPYCYRRTVEFVDYYNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00193701; iTF_00083050; iTF_00312710; iTF_01300989; iTF_00311904; iTF_00313568; iTF_00335174; iTF_01404998; iTF_01256487; iTF_00937396; iTF_00877186; iTF_01052232; iTF_01054436; iTF_01053477; iTF_01456135; iTF_01457485; iTF_01460047; iTF_01454960; iTF_01458514; iTF_00118797; iTF_01318349; iTF_00456238; iTF_00653614; iTF_00348272; iTF_00643312; iTF_00455075; iTF_00717893; iTF_01049769; iTF_00160842; iTF_00628461; iTF_01183918; iTF_01461262; iTF_01224688; iTF_00363352; iTF_00644220; iTF_00424767; iTF_01297599; iTF_00235009; iTF_00234066; iTF_01519426; iTF_01519425; iTF_00176510; iTF_00671027; iTF_01540499; iTF_01540479; iTF_00202709; iTF_00203657; iTF_00324526; iTF_00322641; iTF_00999735; iTF_01043959; iTF_01088601; iTF_01127598; iTF_01375932; iTF_01276341; iTF_01277035; iTF_00812886; iTF_01115094; iTF_01114337; iTF_00384654; iTF_01254039; iTF_00366586; iTF_01486311; iTF_01426757; iTF_01023112; iTF_01181259; iTF_00972303; iTF_00257937; iTF_00797844; iTF_01415131; iTF_01505530; iTF_00979426; iTF_00192165; iTF_01358088; iTF_00303881; iTF_01470601; iTF_01562986; iTF_00191435; iTF_01133003; iTF_00082224; iTF_00082257; iTF_00190036; iTF_00992724; iTF_01563860; iTF_00091414; iTF_01045560; iTF_01189594; iTF_00192891; iTF_00081340; iTF_00991907; iTF_00749096; iTF_00750607; iTF_00315270; iTF_00311170; iTF_00316067; iTF_01300134; iTF_00724881; iTF_00314422; iTF_01378473; iTF_01200974; iTF_01314767; iTF_00435650; iTF_00747555; iTF_01109411; iTF_00199972; iTF_00655396; iTF_00760196; iTF_01175236; iTF_00716805; iTF_01138117; iTF_01237765; iTF_00892870; iTF_01261094; iTF_00258983; iTF_00900711; iTF_00975719; iTF_01427559; iTF_01019528; iTF_00331593; iTF_01236809; iTF_01313898; iTF_00259851; iTF_01399563; iTF_00922189; iTF_00746798; iTF_01376718; iTF_01174352; iTF_00679601; iTF_01074577; iTF_01162353; iTF_01165617; iTF_01177041; iTF_01397553; iTF_00748306; iTF_00045427; iTF_00350259; iTF_01398611; iTF_00817524; iTF_00749782; iTF_01201718; iTF_01259287; iTF_00899705; iTF_01194489; iTF_01374170; iTF_00816635; iTF_00371164; iTF_00741982; iTF_00997824; iTF_01231680; iTF_01235840; iTF_01315584; iTF_01375024; iTF_01521968; iTF_01522754; iTF_00310350; iTF_01116531; iTF_01521203; iTF_01357014; iTF_01055320; iTF_00967294; iTF_01002880;
90% Identity
iTF_01212071; iTF_00894049; iTF_01223521; iTF_00311170; iTF_01044802; iTF_01522754; iTF_00316067; iTF_00991907; iTF_00312710; iTF_00315270; iTF_00335174; iTF_00974822; iTF_01300134; iTF_01395911; iTF_00665769; iTF_00426474; iTF_00694763; iTF_00427437; iTF_00693933; iTF_01318349; iTF_00240846; iTF_00310350; iTF_01521968; iTF_00724881; iTF_00671027; iTF_01116531; iTF_01521203; iTF_00664180; iTF_01396628; iTF_00314422; iTF_01357014; iTF_01541526; iTF_00664951; iTF_00984343; iTF_01254039; iTF_00188249; iTF_00389722; iTF_00976602; iTF_01300989; iTF_01542303; iTF_00311904; iTF_00313568; iTF_00624842; iTF_01314767; iTF_00351937; iTF_00435650; iTF_00747555; iTF_01109411; iTF_00199972; iTF_00655396; iTF_00760196; iTF_01175236; iTF_00716805; iTF_01138117; iTF_01237765; iTF_00892870; iTF_01261094; iTF_00258983; iTF_00900711; iTF_00975719; iTF_01427559; iTF_01486311; iTF_00331593; iTF_01236809; iTF_01313898; iTF_00259851; iTF_01399563; iTF_00922189; iTF_01376718; iTF_00972303; iTF_01174352; iTF_00257937; iTF_00679601; iTF_01074577; iTF_01162353; iTF_01165617; iTF_01177041; iTF_01397553; iTF_00748306; iTF_00045427; iTF_00350259; iTF_01398611; iTF_00817524; iTF_00749782; iTF_01201718; iTF_01259287; iTF_01055320; iTF_00899705; iTF_01194489; iTF_01374170; iTF_00816635; iTF_01415131; iTF_00371164; iTF_00741982; iTF_00967294; iTF_00997824; iTF_01231680; iTF_01235840; iTF_01315584; iTF_01019528; iTF_01023112; iTF_01426757; iTF_01181259; iTF_01133003; iTF_01470601; iTF_01375024;
80% Identity
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