Basic Information

Insect: Neoneuromus ignobilis
Gene Symbol: ZFHX3
Assembly: GCA_029203775.1
Location: CP092089.1:36117871-36131087[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 5.1 4.2e+02 2.6 0.2 1 21 111 131 111 134 0.75

2 15 0.0052 0.42 12.0 0.2 1 23 199 222 199 222 0.93

3 15 0.51 41 5.7 1.5 2 22 308 328 308 331 0.90

4 15 0.087 7.1 8.1 1.4 1 23 343 368 343 368 0.93

5 15 0.006 0.49 11.8 1.6 1 23 386 408 386 408 0.97

6 15 0.0035 0.28 12.5 0.5 2 23 415 437 414 437 0.94

7 15 0.00071 0.058 14.7 3.0 1 23 537 561 537 561 0.92

8 15 0.01 0.83 11.1 0.6 1 22 581 602 581 605 0.89

9 15 0.0046 0.38 12.1 0.2 1 23 656 680 656 680 0.93

10 15 0.0029 0.24 12.8 0.1 3 21 750 768 748 769 0.94

11 15 0.56 45 5.6 2.4 2 19 890 907 889 912 0.90

12 15 0.00022 0.018 16.3 2.5 1 23 1520 1542 1520 1542 0.99

13 15 0.00095 0.077 14.3 0.3 1 23 1638 1660 1638 1660 0.98

14 15 0.012 0.96 10.8 0.4 2 23 1808 1830 1807 1830 0.96

15 15 0.084 6.8 8.2 3.0 3 23 2087 2109 2085 2109 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	5.1	4.2e+02	2.6	0.2	1	21	111	131	111	134	0.75
2	15	0.0052	0.42	12.0	0.2	1	23	199	222	199	222	0.93
3	15	0.51	41	5.7	1.5	2	22	308	328	308	331	0.90
4	15	0.087	7.1	8.1	1.4	1	23	343	368	343	368	0.93
5	15	0.006	0.49	11.8	1.6	1	23	386	408	386	408	0.97
6	15	0.0035	0.28	12.5	0.5	2	23	415	437	414	437	0.94
7	15	0.00071	0.058	14.7	3.0	1	23	537	561	537	561	0.92
8	15	0.01	0.83	11.1	0.6	1	22	581	602	581	605	0.89
9	15	0.0046	0.38	12.1	0.2	1	23	656	680	656	680	0.93
10	15	0.0029	0.24	12.8	0.1	3	21	750	768	748	769	0.94
11	15	0.56	45	5.6	2.4	2	19	890	907	889	912	0.90
12	15	0.00022	0.018	16.3	2.5	1	23	1520	1542	1520	1542	0.99
13	15	0.00095	0.077	14.3	0.3	1	23	1638	1660	1638	1660	0.98
14	15	0.012	0.96	10.8	0.4	2	23	1808	1830	1807	1830	0.96
15	15	0.084	6.8	8.2	3.0	3	23	2087	2109	2085	2109	0.89

Sequence Information

Coding Sequence: ATGGCATGCTGGCAGGCTGTGTGCTCTACCGTGGACCACGCGCGTCCGTCTCTGTCCGACGCGCGGGCCGAGCTTATAAGCCGTCTCTGGCGCGCGACGCGTTTCCCAAATAGCGCGGCTACACCTAACTGTGAAGTGCTTTACCACCGTATTGTTTCCGATCAAAATCAACATACTCCCGAAGAAAAACATTCACCTGATATCAAAGAAcaacaacaatttaaattagaaactgCATTACGAGAACAACAAGAGCTTTTATCGAATCCTGGCCAAAATGACAATTCACATAATCCTTCGTTAGAATTACAACAGCAACAACCCTCGCAACATATGTGCCCTTATTGTAATTACAGTAGTGGATCTGAAATGAGAATTCAAGCCCATGTGCTTGCGCAACACAGTGCAGGTGCTCAACAATCACATGAATCAACGTCGCCACAACAACAAACATCTCAACCACCGTGTCAACAATCTCAATCTCAACAGCagcagcaacaacaacaacagcagcagcagcaacaaCAGCAACAGCAGCAACAACAACAGCAACAGCAGCAACAACAACCGCAATCGAGTCAATCCCAAACGACATATTTATGTCCTTTATGTCAAGACTCATTTAAAGATCGTGCCAGTTTAGAGAAACATGTAATGCAGATACATTCGGTGAACTCGGAAGGTCTGCAACGGTTATTACTTTTAGTAGATCAGAGCCATTGGTTAAATCAAGTAGCGAGAACCCCTAGTACACCGACGAGCCAAAATAATACTACTATGCATACACCACCTAATCAGATGGTTTCACCTAGTTCAGTTTCATCCAAAGATTCGACCAAAAACGATTTTAGAAACGAAGAAAATTTAGAACAAGATATGATATCGCCGAATAGCGAAGAAGTTACTGAAATTGAAGTGGAAAGATGCAATGCATGTTTgaagaattttagaaatatcgacGAACTGTGCATGCATCAGAACGAAACGGGACACCTCGAAATTAAACAAACTCCGAGTGGACCAGGTTACGTTTGTTGGAAGAAAGGTTGTAGTCAGTTCTTTCCCACTGCACACAGTTTACAAACGCATTTCAAAGAAGTACAtgcaaaaaattcaatatcacAAATGTCAGTATCTGAAAAACATGTGTACAAGTATCGCTGCAATCAGTGTTCGCTCGCATTCAAGACattagaaaaattacaattacattCACAATATCATTTAATCAGAGATGCTACGAAATGCGTCTTGTGTGGAAGAAGTTTTCGATCTGTCGTGGCGTTACACAAACACGTCGAGTCTGTACATTCGGAGTTATCTGACGATGAACTCGTTGCATATAAAAACAGCTTATTAAGTAATCCGTTATTACTGGCGGGTCTACAAGGACATGTTCTTGATCCTACCACgacagatttattaaaaagagaaacaATGCGTGATGAAGTAGCTGAAACACCTATAGAGAATGAAGAGCATAAAGAACAAGTCGAGGATGGGGAAAACTCGGACGATAGTACAACGTATAAAGAACAACAATTTTTCGAGGATTATCTAAACAGTCAAGCATTGGCCGAAGACAATTATGGCGATCCTAATAGAAAATACAAATGCCATAGATGTCGCGTAGCATTCACAAGACAGAGTTACCTGACAGCACATAATAAGACGCTGCTTCATCGAAAAGGTGAAAAATTAAGTTATCCCATGGAGAAATATTTAGACCCTAATAGACCTTATAAGTGTGATGTTTGTAAAGAGAGCTTTACACAAAAGAATATCTTATTAGTGCATTACAACTCCGTGAGCCACTTACATAAATTGAAACGTGCGATGCAAGAAcaacaaaataacaataataatcctGTGTCCCCAGGACAACAAGGGCAGCCGAGCAGCGGCAATCCGGCATTAACGCTGACGCCGAAGAGCACGTCATCAGAAGAGGACGAGAAGAAACGGTACAGGTGTAATATATGCAGAGTTGCGTATACTCAAGGTAGCACGCTCGACATTCACATGCGAAGCGTGCTGCACCAAACGCGCGCAAGTAAACTGCAAGATCTGGCGCTGAGCGGACAGCTCGATCTGTCACGGCCGTTAGTCGAACAACCTACCGAACCCCCTTCCACGGCGAGCCCGCCGGGTGGGGGCGCAATGCTACAACCCTCACAGACACCCCCCGCTCCGCCGTCCCCTACCCCACCGCTGCCGATACCGGCCGCTCCACAAGGGATGATGGCCTGTCAAAAGTGCGGTGCCCTTTTCACGAGCCAAGATCAGTTGAATACGCACCAGCAGATGTACTGTATGTTCGCTGTGTCTGGCGGTGGTGGTGCTGGTGTCGGTGGACCGATGGCGATTTTAAATCAACAATGTGATAATGTGACACCGCCGCCGATCGAGCCGGGTAGCGGCGACGGCGATCTAAACAAATTACCTCGTCGGACCGGCTCTCACATGTACAAACATCTTCTTGAGAGTTTCGGATTCGATCTCGTCATGCAATTCAACGAGAACCATCAACGAAGACAGAGACAGCGCGAAGAAGAGCAACGGGAGCGTGCTGCAAATCGACCGCCGACGCCGATTCCGCAGGAAGTCACGCCCGTCGAAGAAGTAATCCCGGAAACGACCACCAGTCTTCCCGAGGTTAGTAAATCGACGTGTCAACATTGCAATAAGGAATTCTCTAGTGTGTGGGTACTCAAGTCGCATTGTGAGGAAATACATAAAGATTTAGTGCCATTggaatttcttgaaaaatatgcacaacaaattaaaaacgaatacgAAAAGAAAGCGGTTGTCGTGACGGCCGCAACGTCGTCGACACTAAACACCGTACCTAGAGTTTCGACTCCCGGTGTAGGTGCGGCGACTGCGACAACGATGACACCGACACCCACAATTACAGTACCAGATTCTACGCCCGAAAAAGATATCGAGGAATCGAAAGAACTCTTACATACAAAGTTAAATATTCAACAGACACCGCCGGAGGCTACGTCGACGGCACCGTCCACGCCGACGTCGTCGTCGACACCCGCCTCCAGCACTGACTCGATTCCCGCGAATATTCAAGCGATGCTCGCACAGACGATGGCGCAGAACCCGATGGCGTTCGCGCAACAGATGTCCGAGATGCAGGCCGCGTTGAATGTGATGCAATTACAGCAacagtttaattttaatccGATGGTTATGAGCCAGATGATGGGAATGGGGCTGCCGCTAGGGCTAAACGCCCTCGCCGCGATGAATCTTCAGCCACCACTAGTACCGTTGATGATGCCGCCGCCGCCTTACGATCCGATGGGGTTGCAAGCGCAATTCTCCCCACAGGATCCGCAGGCGATGATGGCCAAACAACAAGCAGCCATGTTACAACAGCAACAGCAGCAGGTGGTTGCAAACGCGGCAGCAAATCAAAAAAGAGCGCGGACTCGCATCACTGATGATCAATTGAAAATCTTACGCGCCCATTTCGACATAAACAATTCACCATCCGAAGATCAAATTCACGAGATGGCCTCGCAGAGTGGTTTACCACCGAAAGTAATTAAACACTGGTTCCGAAACACATTGTTCAAAGAAAGACAACGAAATAAAGATAGTCCATACAATTTCAATAATCCGCCGTCGACAACATTAAATTTAGAAGAATATGAAAAGACTGGAGAAGCAAAGGTTATGCCTCTCAACACATCTGGAAGTTCCTCTGACGATACCTCAAAACAACAGACAGACATAAAGACTTGTACGACGGTGACGTCAATCGCGTCGACTGAATACCAACCGGAAAGTCAAATTAAGACCGAACCTAAAGAAGAACAAATAGAAGAGACGATTCAAAAAATTGAGACTGATAAATTACCTGATACGCCTATAGATGAGAAaccgaatatttttaatataccttTGAATCTACAACAATCACAGAGTCCGGTACCATCATTGACCGGTTCGGATAATCAAAACATGCCACTAAACTCGAGACCGAACACACCTAACGCTCTCACGCTCACATCGATAATATCTTCTCAGCTCGGTGACGCTCTAACGACCACAAATCCACCAATTTCTATGTCTGTGACACCAACGATGAACAATCCGTTATCTAGTACCATGTTACCGCCTCCAAAATTGACACCACAGAATTTTGCAAACCCTAACAATGTGCAAAACATGCTTCCGCTTACACCGAACAGAAGTTTAAGTCCAAACCGTGGAGATTTCGGCACAATGGGGAATAGTAATGGAAGTAACAGTTCTGGTGGTTCTACTGGAAAAAGAGCAAACCGCACTAGATTCACGGATTATCAAATCAAAGTCCTCCAAGAATTTTTCGAAAACAACGCTTATCCGAAAGATGACGATCTCGAATATTTATCAAAGTTACTAAGTTTAAGTCCACGAGTCATCGTGGTCTGGTTTCAGAATGCTCGTCAGAAAGCACGAAAAGTATACGAAAATCAGCCAGCCGTTGAACCGGCACCTGGCATACCTGAAGAAGCTGGTGCTAATCGATTTCAAAGAACACCCGGTTTGAATTATCAGTGCAAGAAATGTTTATTGGTATTCCAAAGATATTACGAATTGATACGACATCAGAAAACGCATTGTTATAAAGAAGAAGACGCGAAGCGATCAGCTCAGGCTCAAGCCGCCGCTGCTCAAATAGCAGCTGTTTTGAGTTCAGAAGATTCTAATTCGAGTACAACAATCGAACAATCACAAATTCAGCCGCCGATCGCTCAGAGTCCTCAGATACAGAATATACCATCACAGAGTCCTGTCAATCAGCCGACACAGCCATCGACGCCGACTCCATCCGCATCGAATTACACAACCTCTCCGATCTCCACGCCCACGCCTAACCAATCGACCGACACCAAAGAAGGAACGTTTCAGTGTGATAAATGTAATCTAGTTTTTCCAAGATTCGATCTGTGGCGTGAGCATCAACTAGTCCACATAATGAATCCAAACTTGTTTCCAACTTACCCGCCTGATTCGCCGTTCGGAATTCTTCAACAGCACGCGCAACTCCAACAGTTAAATGCAAATTTAGGCGTGACAGATCTAAGCAATAGTTCTGGAACGTCGCCGATTCCACATCCTCTGATGGGAATGTTGAACAATGCCGTGCAGAAACGTAAATTTGACGAGTACGATAACGAAAGCGACGTGTCAGATCAACCGAAAGACAAACGTTTACGGACGACTATATTACCCGAACAGCTAGATtacttatatcaaaaatatcagaTTGAAAGCAATCCATCGAGGAAAATGCTTGAAAACATCGCCAGGGAGGTCGGTTTGAAGAAACGCGTTGTACAGGTATGGTTTCAAAATACTCGCGCGAGAGAACGTAAAGGTCAATTTAGGGCACATGCGCAGGTCATCAACAAACGGTGTCCGTTCTGTCCGGCACTGTTCAAGGTCAAATCCGCGTTGGAGTCCCATCTAACCACAAAACACGCCGACCAGTGCGCGAAAGGTGACATTAACATCGACGCGCTGCCGGACGAGGAGCTCAGTTTGGAATCGGCACCGAGTTTTACATCTGAGGGCGGAAATAAAAATTTCCAACAAAATCCTAATATAATACCGCCTCTGTTTCCGCCTTTCAATCCCGAAATGGAAAATTCTATAAAGAAGTATTACGAAGAAAGTATGAAGAGATATATAAGCGAGTTACAAGCGCACGCGGCGGCGAGTAACGGCGATAAAAGTGAAATTAAGACTGGTAAAGAAGAAGGCGAAGTCCCTTTAGATCTATCGAAACCGGTCGATTTATCGAGACCGATGAAAGTGAGTATGGATCATGAAAAATCATTCATTGATCCTGGACCATTGACCGATTTGAGTGAACGTTCTTTGTGCGACGAACGTAGTGATTCGATGTCTGAAACAACTGAGTTTTACGACGACGAAAGTAACCCTACATCTCCTGCTAGTTCCACGCAAAGTAACCAACAAAGACAGTTGTCCGGAAATGCCGGAACGAAACGTTTCCGTACGCAGATGTCGTCGATACAAGTGAAAGTGATGAAATCATTGTTCAACGATTACAAGACACCGACGATGGCAGAATGTGAGATGCTGGGTCGCGAGATTGGGCTTCCTAAACGTGTCGTGCAAGTATGGTTTCAAAACGCGCGCGCTAAAGAGAAAAAGAACAAGATAGCGTTACAAAAAGTGCTCGGCGGTCCTGAAAATTCATCCGATACGAAAACACCTGATGATTGCAAGTActgtaatttcaaatattcgCACAAGTACTCGGTACAAGATCACATTTTCACCAAGAGTCACATAGCGAATGTGAAAATGCAACTCGAGAGTCTCAGCAACAAAGATAACAATTCTGGGAATATGAGTGACGGCGGGGAGTTCACTGTACCGCCAGTGCCCGGATCATCTTCGGGCGGCACGGTGAACGCTGACTCGACGACCAACATGCAACAGGCGCAAACGTTAAACAACAATCAACATTTGGCGCAGATGCAGTTGTTACAAATGGCCGGTCTCCAAATGGCTGTTAGTAAAGGTGTCGGCGATTCACAGAAAGGAGACGATAACAGTCCGGAGACACTGTTCCAACAACTGTACGCTTTGGGAGGCGGTCAAGCCGGCGGATTCCCTGGTACAAGTCAGTTCCTGCATCCAGCCATGTTCGGGGCGAACGGTGAGTGA
Protein Sequence: MACWQAVCSTVDHARPSLSDARAELISRLWRATRFPNSAATPNCEVLYHRIVSDQNQHTPEEKHSPDIKEQQQFKLETALREQQELLSNPGQNDNSHNPSLELQQQQPSQHMCPYCNYSSGSEMRIQAHVLAQHSAGAQQSHESTSPQQQTSQPPCQQSQSQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQSSQSQTTYLCPLCQDSFKDRASLEKHVMQIHSVNSEGLQRLLLLVDQSHWLNQVARTPSTPTSQNNTTMHTPPNQMVSPSSVSSKDSTKNDFRNEENLEQDMISPNSEEVTEIEVERCNACLKNFRNIDELCMHQNETGHLEIKQTPSGPGYVCWKKGCSQFFPTAHSLQTHFKEVHAKNSISQMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHLIRDATKCVLCGRSFRSVVALHKHVESVHSELSDDELVAYKNSLLSNPLLLAGLQGHVLDPTTTDLLKRETMRDEVAETPIENEEHKEQVEDGENSDDSTTYKEQQFFEDYLNSQALAEDNYGDPNRKYKCHRCRVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNPVSPGQQGQPSSGNPALTLTPKSTSSEEDEKKRYRCNICRVAYTQGSTLDIHMRSVLHQTRASKLQDLALSGQLDLSRPLVEQPTEPPSTASPPGGGAMLQPSQTPPAPPSPTPPLPIPAAPQGMMACQKCGALFTSQDQLNTHQQMYCMFAVSGGGGAGVGGPMAILNQQCDNVTPPPIEPGSGDGDLNKLPRRTGSHMYKHLLESFGFDLVMQFNENHQRRQRQREEEQRERAANRPPTPIPQEVTPVEEVIPETTTSLPEVSKSTCQHCNKEFSSVWVLKSHCEEIHKDLVPLEFLEKYAQQIKNEYEKKAVVVTAATSSTLNTVPRVSTPGVGAATATTMTPTPTITVPDSTPEKDIEESKELLHTKLNIQQTPPEATSTAPSTPTSSSTPASSTDSIPANIQAMLAQTMAQNPMAFAQQMSEMQAALNVMQLQQQFNFNPMVMSQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPMGLQAQFSPQDPQAMMAKQQAAMLQQQQQQVVANAAANQKRARTRITDDQLKILRAHFDINNSPSEDQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNTSGSSSDDTSKQQTDIKTCTTVTSIASTEYQPESQIKTEPKEEQIEETIQKIETDKLPDTPIDEKPNIFNIPLNLQQSQSPVPSLTGSDNQNMPLNSRPNTPNALTLTSIISSQLGDALTTTNPPISMSVTPTMNNPLSSTMLPPPKLTPQNFANPNNVQNMLPLTPNRSLSPNRGDFGTMGNSNGSNSSGGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPAVEPAPGIPEEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCYKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTIEQSQIQPPIAQSPQIQNIPSQSPVNQPTQPSTPTPSASNYTTSPISTPTPNQSTDTKEGTFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNANLGVTDLSNSSGTSPIPHPLMGMLNNAVQKRKFDEYDNESDVSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCAKGDINIDALPDEELSLESAPSFTSEGGNKNFQQNPNIIPPLFPPFNPEMENSIKKYYEESMKRYISELQAHAAASNGDKSEIKTGKEEGEVPLDLSKPVDLSRPMKVSMDHEKSFIDPGPLTDLSERSLCDERSDSMSETTEFYDDESNPTSPASSTQSNQQRQLSGNAGTKRFRTQMSSIQVKVMKSLFNDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKNKIALQKVLGGPENSSDTKTPDDCKYCNFKYSHKYSVQDHIFTKSHIANVKMQLESLSNKDNNSGNMSDGGEFTVPPVPGSSSGGTVNADSTTNMQQAQTLNNNQHLAQMQLLQMAGLQMAVSKGVGDSQKGDDNSPETLFQQLYALGGGQAGGFPGTSQFLHPAMFGANGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00004927;
90% Identity: iTF_00004927;
80% Identity: iTF_01050208;