Aori008640.1
Basic Information
- Insect
- Acanthacorydalis orientalis
- Gene Symbol
- ZFHX3
- Assembly
- GCA_034766995.1
- Location
- CM068315.1:3544562-3558081[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 3.8 5.4e+02 2.6 0.2 1 21 110 130 110 133 0.75 2 15 0.022 3 9.6 0.8 3 23 195 216 193 216 0.94 3 15 0.54 76 5.2 1.5 2 22 302 322 302 325 0.90 4 15 0.065 9.1 8.1 1.4 1 23 337 362 337 362 0.93 5 15 0.0044 0.63 11.8 1.6 1 23 380 402 380 402 0.97 6 15 0.0026 0.37 12.5 0.5 2 23 409 431 408 431 0.94 7 15 0.00053 0.074 14.7 3.0 1 23 531 555 531 555 0.92 8 15 0.0076 1.1 11.1 0.6 1 22 575 596 575 599 0.89 9 15 0.0034 0.48 12.1 0.2 1 23 650 674 650 674 0.93 10 15 0.0022 0.3 12.8 0.1 3 21 744 762 742 763 0.94 11 15 0.41 58 5.6 2.4 2 19 881 898 880 903 0.90 12 15 0.00016 0.023 16.3 2.5 1 23 1512 1534 1512 1534 0.99 13 15 0.00071 0.1 14.3 0.3 1 23 1630 1652 1630 1652 0.98 14 15 0.0088 1.2 10.8 0.4 2 23 1800 1822 1799 1822 0.96 15 15 0.099 14 7.5 3.0 3 23 2079 2101 2077 2101 0.89
Sequence Information
- Coding Sequence
- ATGGCATGCTGGCAGGCTGTGTGCTCTACCGTGGACCACGCTCGTCCGTCTCTGTTCGACGCGCGGGCCGCCCGCATGAGCCGTCTCTGGCGCGCGACGCGTTTCCCAAATAGCGCGGCTACACCTAACTGTGAAGTGCTTTACCACCGTATTGTTTCCGATCAAAATCAACATACTCCCGAAGAAAAACATTCACCCGATATCAAAGAACAGCaacaattcaaaatagaaaCCGCATTACGAGAACAGCAAGAGCTTCTTTCGAATCCTGGCCAAAATGACAGTTCGCATAACTCCTCATTAGAATTACAACAACAACCCTCGCAACATATGTGCCCTTATTGTAATTACAGTAGTGGGTCTGAAATGAGAATTCAAGCCCATGTGCTAGCTCAACACAGTGCAGGTGCTCAACAATCGCATGAAACTACGTCGCCACAACAACAAACATCTCAACCTCCGTGTCAACAATCTCAATCTCAACAGCAACAGCAGCAACAGCAacaacagcagcagcagcaacagcagcagcagcagcaacaACAACAACCGCAACCAACTCAGTCACAAATGACATGCTTATGTCCGTTGTGTCAAGACTCGTTTAAAGATCGTGTCAGTTTAGAGAAACACGTGATGCAAATACATTCGGTGAACTCGGAAGGTCTGCAACGGTTATTGCTTTTAGTAGATCAAAGCCATTGGTTAAATCAAGTGGCGAGAACTCCTAGTACACCGACAAGCCAAAACAACGCTACTATGCACACGCCACCGAATCAGATGGTGTCGCCTAGTTCAGTTTCATCCAAAGATTCGACCAAAAACGATTTTAGAAACGAAGAAAATTTAGAACAAGATATGACGTCGCCGAACGGCGAAGAGGTCACTGAAATTGAAATGGAGAGATGTAGCGCGTGTTTGAAGAATTTTCGAAATATCGACGAACTGTGCATGCATCAAAACGAAACGGGACATCTCGAAATTAAACAGACGCCGAGTGGACCGGGCTACGTCTGTTGGAAGAAGGGCTGCAGTCAGTTTTTCCCGACCGCACACAGCCTACAGACGCATTTCAAGGAAGTGCATGCAAAAAATTCGATATCGCAAATGTCTGTGTCGGAGAAACATGTGTACAAGTACCGCTGCAATCAGTGTTCGCTCGCATTCAAGACACTAGAAAAGTTACAGTTACATTCACAATATCACCTAATCAGAGACGCCACGAAGTGTGTTCTGTGCGGAAGGAGTTTCCGGTCCGTTGTGGCACTACACAAGCACGTTGAATCCGTGCATTCGGAATTGTCGGACGATGAGCTCGTCGCGTATAAGAACAGCTTGTTGAGTAATCCGTTATTGCTGGCGGGTCTGCAGGGGCACGTTCTCGATCCGACCACGACGGATCTGTTGAAAAGAGAAACGATGCGCGACGAAGTAGCCGAAACGCCTATAGAGAACGAAGAGCACAAAGAGCAAGTCGAGGACGGAGAGAACTCTGACGACAGTGCGACATACAAGGAGCAGCAATTCTTCGAAGATTATCTGAACAGCCAAGCGCTCGCCGAAGACAATTACGGCGACCCTAATAGAAAATACAAATGCCACAGATGTCGCGTGGCGTTCACAAGACAGAGTTACCTGACGGCACACAATAAAACGTTGCTTCATCGAAAAGGTGAAAAATTAAGTTATCCCATGGAGAAGTATTTAGACCCTAATAGACCTTATAAATGTGATGTGTGTAAGGAGAGCTTTACGCAAAAGAATATCTTGTTAGTGCATTACAACTCCGTGAGCCACTTGCATAAATTGAAACGTGCGATGCAAGAAcaacaaaataacaataataatccTGTGTCCCCAGGACAACAAGGACAGCCGAGCGGCGGCAATCCGGCATTAACGCTGACGCCGAAGAGCACGTCGTCGGAAGAGGACGAGAAGAAACGATACAGGTGTAACATATGCAGAGTTGCGTACACGCAAGGCAGCACGCTCGACATTCACATGCGGAGCGTGCTGCACCAAACGCGCGCGAGTAAACTGCAAGACCTAGCGCTGAGCGGGCAGCTCGATCTGTCACGGCCGTTAGTCGAACAGCCTACCGAACCCCCTTCCACAGTGAGCCCGCCGGGTGGGGGCGCGATGCTACAACCCTCACAGACACCCCCCGCTCCGCCGTCCCCTACTCCACCGATGCCGATACCGGCCGCTCCGCAAGGGATGATGGCCTGTCAAAAGTGCGGTGCCCTTTTCACGAGCCAAGATCAGTTGAACACGCACCAGCAGATGTACTGTATGTTTGCTGTGTCGGGCGCTGGTGCCGGTGGACCCATGGCTATCTTGAACCAACAATGTGATAACGTGACACCGCCGCCGATCGAGCCGGGCACCGGCGACGGCGACCTGAACAAATTACCGCGTCGCACCGGCTCACACATGTACAAACATCTGCTCGAGAGTTTCGGATTCGATCTCGTCATGCAATTCAACGAGAACCATCAACGAAGACAGAGGCAGCGTGAAGAAGAACAACGGGAGCGTGCAGCAAATCGACCGCCGACGCCGGTTCCGCAGGAAATCACGCCCGTCGAAGAAGCAATCCCGGAAACGACCACCAATCTCCCCGAGGTTAGTAAATCGACGTGTCAACATTGCAATAAGGAATTCTCTAGCGTGTGGGTACTCAAGTCGCATTGCGAGGAAATACATAAAGATTTAGTGCCATTGGAATTTCTTGAAAAGTATgcacaacaaattaaaaacgaGTACGAAAAGAAGGCGGTCGTCGTGACGGCCGCAACGTCGTCGACACTAAACACCGTACCACGAGTTTCGACTCCTGGTGCGGGTGCGGCGACTGCGACGACGATGACACCGACACCCACAATTACAGTACCAGATTCTACGCCCGAAAAAGACGTCGAGGAATCGAAAGAACTCTTACATACAAAGTTAAATATTCAACAGACACCGCCGGAGGCCACGTCGACGGCACCGTCCACGCCGACGTCGTCGTCGACACCCGCCTCCAGCACTGACTCGATTCCCGCGAATATTCAAGCCATGCTCGCGCAGACGATGGCGCAGAACCCGATGGCGTTCGCGCAACAGATGTCCGAGATGCAGGCCGCGTTGAACGTGATGCAATTGCAAcaacagtttaattttaatccGATGGTTATGAGCCAAATGATGGGAATGGGGCTACCGCTCGGGCTGAACGCCCTCGCCGCTATGAACCTCCAGCCACCGCTCGTACCGTTGATGATGCCGCCGCCACCTTACGATCCGATGGGGTTGCAAGCGCAATTCTCCCCGCAGGATCCGCAGGCGATGATGGCCAAACAACAAGCGGCCATGTTACAACAGCAACAGCAGCAGGTGGTTGCAAACGCGGCAGCAAATCAAAAAAGAGCGCGGACTCGCATCACTGACGATCAGTTGAAAATCTTGCGCGCCCATTTCGACATAAACAATTCACCATCCGAAGATCAAATTCACGAGATGGCCTCGCAGAGCGGTTTACCGCCGAAAGTAATCAAACACTGGTTCCGAAACACACTGTTCAAAGAAAGACAACGAAATAAAGATAGTCcgtataatttcaataatccACCGTCGACGACACTAAACCTCGAAGAATACGAAAAGACTGGAGAGGCAAAGGTCATGCCGCTCAACGCAACCGGAAGTTCCTCTGACGATACCTCGAAACAACAGACCGACATGAAAACTAGTACGGCGGTGACGTCAATGGCGTCGACCGAATACCAGCCGGAGAGTCAGATCAAGACCGAACCGAAAGAAGAGCAGATAGACGAGCCGAATCAAAAAATTGAGACTGATAAATTACCTGATACGCCTATAGACGAGAAAccgaacatttttaatataccaCTGAATCTGCAGCAGTCACAGAGTCCGGTACCGTCGCTGACCGGTTCGGATAATCAGAACATGCCGCCGAACTCGAGACCGAACACGCCGAACGCCCTCACACTCACATCGATTATATCTTCTCAGCTCGGTCCTGACGCCATAACGACGACGAATCCTCCGATTTCTATGTCTGTGACACCGACGATAAACAATCCGCTGTCCAGTACGATGTTACCGCCTCCCAAGTTGACGCCGCAGAATTTCGCGAATCCTAACAACGTGCAGAATATGCTTCCGATGACGCCGAACAGGAGTTTGAGTCCGAACCGCGGCGACTTCGGCACGATGGGCAACAGTAACGGAAGCAGTAGTTCTGGCGGTTCTACTGGAAAACGAGCGAATCGCACTAGATTCACGGACTACCAAATCAAAGTGCTTCAagaatttttcgaaaataacgCTTATCCGAAAGACGACGATCTCGAGTATCTGTCGAAATTGTTAAGTTTGAGTCCGCGTGTCATCGTCGTCTGGTTTCAGAACGCCCGCCAGAAAGCGCGAAAAGTCTACGAGAATCAGCCGGCCGTCGAACCGGCGCCGGGTATACCCGAAGAGGCCGGCGCCAATAGATTTCAGCGAACGCCCGGCTTGAACTATCAATGCAAGAAGTGCTTATTGGTGTTCCAAAGATATTACGAACTGATACGACATCAGAAAACGCACTGTTATAAGGAGGAGGACGCGAAGCGATCGGCTCAAGCGCAAGCGGCCGCCGCTCAAATAGCGGCCGTCTTGAGTTCAGAAGATTCGAACTCGAGCACGACGATCGAACAGTCGCAGATCCAGCCGCCGATCGCGCAGAGTCCTCAGATACAGAACATACCGTCACAGAGTCCTGTGAATCAGCCGACACAACCGTCTACTCCGACCCCATCCGCATCGAATTACACGACCTCGCCGATTTCGACACCGACGCCCAATCAGTCGACCGACACCAAAGAGGGAACGTTCCAATGCGACAAGTGTAATCTAGTGTTCCCGAGATTCGATTTGTGGCGCGAGCACCAGCTCGTCCACATAATGAATCCGAACTTGTTTCCGACTTATCCGCCCGACTCGCCGTTCGGCATCCTCCAACAGCACGCGCAGCTCCAACAGCTGAACGCGAACCTGGGCGTGACAGATCTGAGCAACAGTTCTGGAACGTCGCCGATTCCGCACCCACTGATGGGCATGCTGAACAATGCCGTGCAGAAACGGAAATTCGACGAGTACGATAACGAAAGCGACGTGTCCGACCAGCCGAAAGACAAACGTTTGCGGACGACCATACTGCCTGAGCAGCTAGATTACTTGTATCAAAAATATCAGATCGAAAGCAATCCGTCGAGGAAAATGCTTGAGAACATCGCCAGGGAGGTCGGTCTGAAGAAACGCGTTGTACAGGTATGGTTTCAAAATACTCGCGCGAGAGAACGTAAAGGTCAATTTAGGGCACATGCGCAGGTCATCAACAAACGGTGTCCGTTCTGCCCGGCACTGTTCAAGGTCAAATCCGCGTTGGAGTCCCATCTAACGACAAAACACGCCGACCAGTGCGCGAAAGGCGACATTAACATCGACGCGCTGCCAGACGAGGAGCTCAGTTTGGAATCGGCGCCGAGCTTTACATCGGAGGGCGGAAATAAAAATTTCCAACAGAATCCTAACATGATACCGCCACTGTTTCCGCCATTCAATCCCGAAATGGAAAATTCGATAAAGAAGTATTACGAGGAGAGCATGAAGCGGTATATAAGCGAGTTACAAGCGCACGCGGCGGCGAGTAACGGCGATAAGAGTGAAATTAAGACTGTGAAAGAGGAAGGCGAGGTCCCTTTAGATCTGTCGAAGCCGGTCGATCTGTCGAGACCGATGAAAGTGAGTATGGATCATGAGAAGTCGTTCATTGATCCGGGACCATTGACCGATCTGAGCGAACGTTCCCTGTGCGACGAACGTAGCGACTCGATGTCCGAAACGACAGAGTTCTACGACGACGAGAGCAATCCGACGTCGCCGGCTAGTTCGACGCAGAGCAATCAGCAGAGACAGTTGTCCGGAAACGCCGGAACGAAACGATTCCGTACGCAGATGTCGTCGATTCAGGTGAAAGTGATGAAATCACTCTTCAACGATTACAAGACGCCGACGATGGCGGAATGCGAGATGCTGGGTCGGGAGATCGGGCTTCCCAAACGTGTCGTGCAAGTGTGGTTTCAGAACGCGCGCGCCAAAGAGAAAAAGAATAAGATAGCGTTACAGAAAGTGCTCGGCGGTCCCGAGAACTCGTCCGATTCGAAAGTGCCCGACGACTGCAAGTACTGCAATTTCAAATATTCGCACAAGTACTCGATACAAGATCACATTTTCACGAAGAGTCACATCGCGAACGTGAAAATGCAACTCGAGAGTCTCAGCAATAAAGATAACAACTCCGGGAACATGAGTGACGGCGGGGAGTTCACTGTGCCGCCGGTGCCCGGATCGTCTTCCGGTGGCACGGTGAACGCCGACTCCACGACCAACATGCAACAGGCGCAAACGTTGAACAACAATCAGCATTTGGCGCAGATGCAGCTGTTGCAAATGGCCGGACTCCAGATGGCTGTCAGTAAAAGTGTCGGCGATACGCAGAAAGGAGACGATAACAGTCCGGACACACTGTTCCAGCAACTGTACGCCTTGGGCGGCGGTCAGGCCGGAGGATTCCCTGGTACAAGTCAGTTCCTGCATCCAGCCATGTTCGGGGCGAACGGTGAGTGa
- Protein Sequence
- MACWQAVCSTVDHARPSLFDARAARMSRLWRATRFPNSAATPNCEVLYHRIVSDQNQHTPEEKHSPDIKEQQQFKIETALREQQELLSNPGQNDSSHNSSLELQQQPSQHMCPYCNYSSGSEMRIQAHVLAQHSAGAQQSHETTSPQQQTSQPPCQQSQSQQQQQQQQQQQQQQQQQQQQQQQPQPTQSQMTCLCPLCQDSFKDRVSLEKHVMQIHSVNSEGLQRLLLLVDQSHWLNQVARTPSTPTSQNNATMHTPPNQMVSPSSVSSKDSTKNDFRNEENLEQDMTSPNGEEVTEIEMERCSACLKNFRNIDELCMHQNETGHLEIKQTPSGPGYVCWKKGCSQFFPTAHSLQTHFKEVHAKNSISQMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHLIRDATKCVLCGRSFRSVVALHKHVESVHSELSDDELVAYKNSLLSNPLLLAGLQGHVLDPTTTDLLKRETMRDEVAETPIENEEHKEQVEDGENSDDSATYKEQQFFEDYLNSQALAEDNYGDPNRKYKCHRCRVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNPVSPGQQGQPSGGNPALTLTPKSTSSEEDEKKRYRCNICRVAYTQGSTLDIHMRSVLHQTRASKLQDLALSGQLDLSRPLVEQPTEPPSTVSPPGGGAMLQPSQTPPAPPSPTPPMPIPAAPQGMMACQKCGALFTSQDQLNTHQQMYCMFAVSGAGAGGPMAILNQQCDNVTPPPIEPGTGDGDLNKLPRRTGSHMYKHLLESFGFDLVMQFNENHQRRQRQREEEQRERAANRPPTPVPQEITPVEEAIPETTTNLPEVSKSTCQHCNKEFSSVWVLKSHCEEIHKDLVPLEFLEKYAQQIKNEYEKKAVVVTAATSSTLNTVPRVSTPGAGAATATTMTPTPTITVPDSTPEKDVEESKELLHTKLNIQQTPPEATSTAPSTPTSSSTPASSTDSIPANIQAMLAQTMAQNPMAFAQQMSEMQAALNVMQLQQQFNFNPMVMSQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPMGLQAQFSPQDPQAMMAKQQAAMLQQQQQQVVANAAANQKRARTRITDDQLKILRAHFDINNSPSEDQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNATGSSSDDTSKQQTDMKTSTAVTSMASTEYQPESQIKTEPKEEQIDEPNQKIETDKLPDTPIDEKPNIFNIPLNLQQSQSPVPSLTGSDNQNMPPNSRPNTPNALTLTSIISSQLGPDAITTTNPPISMSVTPTINNPLSSTMLPPPKLTPQNFANPNNVQNMLPMTPNRSLSPNRGDFGTMGNSNGSSSSGGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPAVEPAPGIPEEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCYKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTIEQSQIQPPIAQSPQIQNIPSQSPVNQPTQPSTPTPSASNYTTSPISTPTPNQSTDTKEGTFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNANLGVTDLSNSSGTSPIPHPLMGMLNNAVQKRKFDEYDNESDVSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCAKGDINIDALPDEELSLESAPSFTSEGGNKNFQQNPNMIPPLFPPFNPEMENSIKKYYEESMKRYISELQAHAAASNGDKSEIKTVKEEGEVPLDLSKPVDLSRPMKVSMDHEKSFIDPGPLTDLSERSLCDERSDSMSETTEFYDDESNPTSPASSTQSNQQRQLSGNAGTKRFRTQMSSIQVKVMKSLFNDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKNKIALQKVLGGPENSSDSKVPDDCKYCNFKYSHKYSIQDHIFTKSHIANVKMQLESLSNKDNNSGNMSDGGEFTVPPVPGSSSGGTVNADSTTNMQQAQTLNNNQHLAQMQLLQMAGLQMAVSKSVGDTQKGDDNSPDTLFQQLYALGGGQAGGFPGTSQFLHPAMFGANGE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00004495; iTF_01050208; iTF_01050690;
- 90% Identity
- iTF_00004495; iTF_01050208; iTF_01050690;
- 80% Identity
- iTF_00004495;