Nign004637.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Neoneuromus ignobilis
Gene Symbol
-
Assembly
GCA_029203775.1
Location
CP092088.1:12087110-12090906[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.0037 0.3 12.4 0.8 2 23 247 268 246 268 0.97
2 18 2.4e-05 0.002 19.3 2.8 2 23 297 318 296 318 0.95
3 18 0.00046 0.037 15.3 1.6 1 23 324 346 324 346 0.97
4 18 6.1e-05 0.005 18.0 1.8 1 23 353 375 353 375 0.97
5 18 0.00027 0.022 16.0 2.0 1 23 381 403 381 403 0.99
6 18 0.00048 0.039 15.2 0.5 1 23 409 431 409 431 0.95
7 18 0.003 0.24 12.7 0.6 1 23 438 460 438 460 0.97
8 18 0.15 12 7.4 2.9 1 23 466 488 466 488 0.79
9 18 0.00022 0.018 16.3 1.1 1 23 494 516 494 516 0.94
10 18 0.00061 0.049 14.9 1.2 1 23 523 545 523 545 0.97
11 18 1.6e-06 0.00013 23.0 4.7 1 23 551 573 551 573 0.99
12 18 0.00046 0.037 15.3 1.1 1 23 579 601 579 601 0.95
13 18 0.03 2.4 9.6 1.0 1 23 608 630 608 630 0.96
14 18 0.00035 0.029 15.7 1.6 1 23 636 658 636 658 0.98
15 18 0.0013 0.1 13.9 1.9 1 23 664 686 664 686 0.96
16 18 0.0043 0.35 12.2 0.4 1 23 693 715 693 715 0.97
17 18 4.3e-06 0.00035 21.7 1.0 1 23 721 743 721 743 0.99
18 18 0.0037 0.3 12.5 0.8 1 19 749 767 749 769 0.96

Sequence Information

Coding Sequence
atgttaaaaaagtcaTACCCTGAGGATTTTCTACCGCaaacaagagtttttgagtggTACAAGGCGTTCAAAGAGGGCTGTGAAGTTGTTGATGATGAACCACAATCTGGACGCCTCTTgacatcaactgacgacgaaTATACAATTTTCGGATGttgtaaatatgttTGTAAGAATGAAAGATTATCGTCGTTCATCTGCCATTCGTGTGCTGCGTATTTGAAGACGCTCATTGTTTTCCGCAATAAATGTATCGAAACAGAGTCTGCATTATGTGATTGTCTTCGAGATTCGTGCTTCGACATAGAAGTAAAAAAGGAACCTGAGGAACCTGAGGACAAGATAACAGTAATCGAAAAAGAATGTAGTTTTTTCATGccggaaaaaaattcttttcttcAATGTTTACGAACCGATATCGATTCGTGCACAGAAAACGTCGATGAACCGAATATAGTAAAAGTTAAAACCGAAGTAGACGACGAAGAAACTAATGACGAGAGAACGCAGTCATGTTTTTCTACATCTTACGAGAGAGGATCGGATGAAAATCTCAGAACGTTCCTTTCGTTACAAGAATTTATTGATATCAAAGAGGACCACGAGAATTTTGTCGACGATGAGAACACAACGTCGGAAGTACCGATCGACGCAAGAGAGACACGCGCGACGGATTCGGACAACAACGAAGATCGATCGTTAGAAAGTAGAAGAATTCGTTCAGGTCACGATTCGATCACTTGTGACTTGTGCAGTGGGTCGTTCGAGACGAAGACACATCTCGACGTACATTTGAAAATACACTGCGAAGGAAAAGAAGATCTCCGTGCGACGAAGTCGCGCCGTCGACGAGCGACTAAGAACGTCGATGTCTTCGGTGGACCAATTCCATGCGATCAATGCAAAATGTCGTTCTCGACGAAACATCAGTTACGCAAACACATGTACCTCCATACCGGCGAGAAGCCGTTCAAGTGCGACACGTGCGGCATGTCGTTcgttaataaatatagattagaCCAACACTATTTCGTGCATtcgaaaaaaaagaaaccgttCGCGTGCGAACTGTGCACGAAATCGTTCTTCAACGCCTGGCATTTGAACGCGCACAGGAACCGGCACCTCAGCAAAAAACCGTTCAAATGTAACGAATGCGAAAAATCGTTTTTGTCCAACAAATATCTGATCTCCCATAAGAGAGTTCACTCGGGTGAAAACCTGTTCAAGTGCGACACGTGCGACATGtcgttcattaataaaattggattaaaccaacactcctacgtgcattccaaaaaaaagaaaccgttTGCGTGCGATCTGTGCACGAGATCGTTCTTTAGCCTCGGGACTTTGGAAGGGCACAGGAATCGGCACCTTGGCAAAAAACCGTTCAAGTGcaacgaatgcgaaaagtcgttttcgtgCAACTTAATTCTGGTCCggcataaaaaaattcacacgGGTGAAAACCTGTTCAAGTGCGACACGTGCGGAAAGTCGTTCcctaataaatatagattagaTATACACTCCTacgtgcattccaaaaaaaagaaaccgttCGCGTGCAATCTGTGCACGAAATCGTTCTTTGACCCTGGGTGTCTGCTTGATCACAGGAATGTGCACCTCGGCAAAAAACCGTTTAAGTGCAACGgatgcgaaaagtcgttttcgACCAAAAGACATCTTAGAGACCATAAGAGAGTTCACACGGGTAAAAACTTGTTCAAGTGCGACACGTGCGATATGTCGTTCGCTGATAAAACTAAATTAGACCGACACTCCTACGTGCATTCTAAAAAAAAGAAGCCGTTCGCGTGCGATTTGTGTACGAAATCGTTCTTAAGCCCCGTGCATTTGGACGCACACAAGACCCGGCACCTCGTCAAAAAACCGTTCAAGTGcaacgaatgcgaaaagtcgttttcgtgGAACAAAAGTTTGGTCCagcataaaaaaattcacacgGGTGAAAACCTGTTCAAGTGCGACACGTGCGACATGTCGTTCGTTACTAAAACTAAATTAGATCAACACTTCTAtgtgcattccaaaaaaaagaaaccgttCGCGTGCGATCTGTGCTCAAAATCGTTCTTCACCGCCGTGCGTCTGGTCTCGCACAAGAACGTCCACCTCGGCAAAAAACCGTTCAAGTGcaacgaatgcgaaaagtcgtttACGAGCAACATACTTCTGGTCCAGCATAAGAGAGTTCACACGGGTGAAAACCTGTTCAAGTGCGACACGTGCGATATGTCGTTCgctaataaaactaaattagatcaacactcctacCACCGGATGTCTGGTCGCGCACAGGAAGCGGCACCTTGGCAAAAAACCATTCAAGTTCAACGATTGCGAAAAGTCGTATTTGGGCATCAAGGATCTCCTGAGACACAAGTAGGTGCACATGGGCGAAAAAACGGTTTGTGCGATGGCGCGTTTAGACTGAGAGTGTATTTGCGGAAATATATGTATTCTCATACCAGACAGAAAATGTCGCATCGATGTGATATGTGCGGATAG
Protein Sequence
MLKKSYPEDFLPQTRVFEWYKAFKEGCEVVDDEPQSGRLLTSTDDEYTIFGCCKYVCKNERLSSFICHSCAAYLKTLIVFRNKCIETESALCDCLRDSCFDIEVKKEPEEPEDKITVIEKECSFFMPEKNSFLQCLRTDIDSCTENVDEPNIVKVKTEVDDEETNDERTQSCFSTSYERGSDENLRTFLSLQEFIDIKEDHENFVDDENTTSEVPIDARETRATDSDNNEDRSLESRRIRSGHDSITCDLCSGSFETKTHLDVHLKIHCEGKEDLRATKSRRRRATKNVDVFGGPIPCDQCKMSFSTKHQLRKHMYLHTGEKPFKCDTCGMSFVNKYRLDQHYFVHSKKKKPFACELCTKSFFNAWHLNAHRNRHLSKKPFKCNECEKSFLSNKYLISHKRVHSGENLFKCDTCDMSFINKIGLNQHSYVHSKKKKPFACDLCTRSFFSLGTLEGHRNRHLGKKPFKCNECEKSFSCNLILVRHKKIHTGENLFKCDTCGKSFPNKYRLDIHSYVHSKKKKPFACNLCTKSFFDPGCLLDHRNVHLGKKPFKCNGCEKSFSTKRHLRDHKRVHTGKNLFKCDTCDMSFADKTKLDRHSYVHSKKKKPFACDLCTKSFLSPVHLDAHKTRHLVKKPFKCNECEKSFSWNKSLVQHKKIHTGENLFKCDTCDMSFVTKTKLDQHFYVHSKKKKPFACDLCSKSFFTAVRLVSHKNVHLGKKPFKCNECEKSFTSNILLVQHKRVHTGENLFKCDTCDMSFANKTKLDQHSYHRMSGRAQEAAPWQKTIQVQRLRKVVFGHQGSPETQVGAHGRKNGLCDGAFRLRVYLRKYMYSHTRQKMSHRCDMCG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01050564; iTF_01050566;
90% Identity
-
80% Identity
-