Nign008742.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Neoneuromus ignobilis
Gene Symbol
egg
Assembly
GCA_029203775.1
Location
CP092089.1:34414499-34433729[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.1 5.9e+03 -2.2 0.1 58 76 381 417 337 418 0.56
2 3 2 1.1e+04 -3.0 0.0 16 35 1200 1219 1194 1220 0.90
3 3 2.7e-10 1.5e-06 28.6 0.0 9 69 1705 1761 1699 1768 0.83

Sequence Information

Coding Sequence
ATGAGACCTCTCGCCAAAAATTTCGCGACGCCGCCTGTTATAGCCAACGTCCGTCTCTGCGACTCATATCATGGATGCCGGCTACAACCGGCGTTAACCTCTAGAGGACTAGGATTTCTATTAACAACAGTCAGTTTACTAAATGCAGCTTCACTTCATCGAATTGCTAGAGACTTACCAGAGAAAGAAATTCCAAAAAATGATCGTATATCACATATTATTAGAGATCAGTACAAAACAAATCCTGAGTACAAAAATAACGAAAGTGAAGAACTAGATAAATTTGAAGCACTTGAAAAAAAGAATACTCAATATGAAAATGTCTATAAATCATCAAAAGTTTCATCACTTGAAGATTCATTATCACATGTATTTGATCAACAAACTGATGAAACAAAACATTTTAGAGgttctacaaaatattttacaacactTAGTAATTTAGATCTACCTACAACAAcagctaaaaataatttagtaaaacaatcaaatggaaataaattagaaacaaaCATCAACTTACCTCCAATAAAAAATGAAGTGGGTAATATAATTCAAACTCAAAGTTCAgataaagaaaatgtaaaatatgaacTAAATGATGATTCTGAGGTTCCAAGTACAGAATCTAACAAAAAATCTAGTCATGTAATTCATACTAGTACCAAAAACGCAATTAAagatataaatcaaaatgaaaatgtaaaacaaaCAGGAAACACTACAAATATAGAAtcacaaaatttacaaaatgataaAAGTGAAATAGTATCTGAAAGAACTGAAACCGGACGTTCATTTGATATAGACAAGTATATTTCACcagaatttcataatattaataatgtttatactcAGATTAGTTCAGCGGAAGCTGAACGATATGCAGATCCAAATAATTATGGTGAAATATATCACTCGACAAAACCTTTTGGTAAAATGTTTTCTTACAGCATTACTCACGACTATGACACAGAATTAACAACACCCAAATCAACTTTATTTGATAGGAAGTTTCACCAAATTtccaatgatattaaatatagtttagatcaagatgaaaatttatctgaaaaaaattctaatcagTCAGACAATATAGGTAAAtcGCCAGTTATCACACATTTACAATCTACAACAAAATCAACAGAATATTCTACTGAAAAGATACAAAACACAGATAAACCAACAACTTCTTTAGATGAAACAACTTTTGAACAATTTGAATTTGATACAACAGAAAATGTTGACCGAAAAATAATCCGATCAACAGATACAATCTCTTTCATTGAAACTACAGTAACATCTTCTTCTATACCATTGGAAAACACATTGTCTGAAAAAGAAACAACAGAAGTATATACTGAAACGATACCATCAGAAGTAAATAATACAAGTcaacaaaatacatttaataattctgAAGAATCAATTACATTAGGAAAAACAGAAAAGACATTATTTTCTACCATAAAAACAGCTAAAAATTTACACATTCCTAAATCAACTACAGAAATGGAAACTGAATCAACATCATATATTGTACTAAATTCAGATGATAAAACAACATTTGCATATATTTCTGATGATCAATCATCAACATTGTCTACACAAAATACTAATGATATTACAACAcaaagttcaatttttaatgaattcaataCAAAACCTATTATTGTAACAGAAGAAATTATAAACTCAACCACACCAGAACTGATTAATGTTTCAGAAGATGAACTTACACAGACTACAACTAATAATGTTAATACTACTACCTTAGATAACAAATCTATTGAAATGACAACATTTGAAATAAAGATTTATGCTTCAACTGAAAAACTTGACGCTGTATCTGAAAATACAACTAGTCAAAGTAGTGAAATTATTACAAgtacattaaaaattgaatcaaCAACTCTTAATAAACCAGAAAATGAACCACAGGTAACAcctttaatatcaaaaatagaaaatgatgaTGCAGATGGAGATGGAGATCAATTAGAAAATCAACCAGAAACAAATTATAAAGTTAATCATAATTTACAAGATTATGAGGATTTTACTAATGAAGCAAACGATAATCAAGAAGAACATCAAGCATCtgttactaataaaattaataaaaatgatgaaccatcaaatttaaacaataaagtaTATAAGCCATTGAATACTATAATTGCACCGACTGAAGAATCAACAGAAGAATCAACTACAGAACCCGAAGAAAATATCGAAGAAGAGTTAACAATTGGTACCGTGGCAGCAATAATAATTGCAAGTGTAGCAGTCTTATGTTTAGTCTTATTGGCTTTATTATTAATAATTATGAGAAAACGACAAAGCCGTCTAACATATGGTCAACGTTGTACTCCAGTAAGCTTAGATGCATACAGTCTTGACAgtgtttctatttataatagtgTAAGGAGAAAAGGAGGTATTCGTGCATCTAAACGGTCATATGGAAATCCTGCATTTGAAGATtctAGTACAGTAACAAATCCAATGAATTTTGCTGCAATggcaaattttattattgataaagaaGCAATTATGAAAGAATTTGAAGATATACCTCAAGTCttagttgaaaataatgaattaccTGAAGGTTGCGAATCAAAGAATCGTTATGCAAATGTAATACCTTTACCAGAAACAAAAGTAGTTCTTTCTTTAGTTGAAGGAGATATTAACAGTGATTACATTAATGCAAATTTTGTACGGGGACCAAAGAATgcaaaatcatattatatagcATGTCAAGCACCTATGCAAGAAACAATTGATGATTTTTGGAGGATGATTTGGGAACAACAAAGTCgtgttattttaatgttaactgACTTAGTAGAAAATGGaattaatatggTTTCAAATTGTTGGCGTGAAATAACACATTTATGGTATATAGGATGGCCTGAACGTGGAGTACCTGAAGAAGCAAACTCAATAATAGCATTTTTAATAGAAGCTCGAAGTTACCTTAAAGTTAATCTCAATAGTTATCAAACAAATCAAAATGGccaaaaaatatcaGAAAATGGCTATATTGGAGAAGATGTAAGTGGACAGGGTCCAGTTGTGGTACATTGTAGTCCAGGTACAGGAAGAACAGGCACAGTTATTGCTTGTGACGTAGCAATTCGAGAATTCGAACTCTTACGAATGGTTGATATTCCAAAAACAGTGTATCGAATACGAAGAGATCGAGCAGGTGCTGTGCAAACACTAGAAGAAGTTATAGACCTAGATGATTCAAATGATGAAGATAAAAGGCCGTCTATAAAGCGACCTCCTCGAAAATGTATCAATGCAGAATGTACAGGCGATGATACTGACTTGAAAGTTGCAGCAAGTTATTGTATAAGTTTCTTCAAAGTTAagtgtaatagaaaaaaaaagcAATTAGTATGTAAAGATTGTAGAAAAATGTGTTTGGACAATATGCAGgTAATGGCTGATATGTTATTGAAGAGAGAACCTATTTTTGATCATAAAATTCCAATGAATGTTGATTCTGTCGAAATTATTGATTCTGATGAAGATAATACTGaagatgaaaaagaaaaaagtacttTAGAAGAAAAAGAAAGggaagaaattaataaaaaaattaataaagcatttaataaatatgatattaattttcaaattgaatggGCAAAAGATAAACTTGAAAAAGACAATAATAGAAATGAAGaacaattaaaagaaattgatGAACTATTGAAACAATTACAAGTGAAAGCAGATTTAGTAAGATCTTCAATATACAGCAATAGACCACGAAATACAGAATTAGAACCTTTAGATATAAATGATGATTATTCTGTAAGAGTTATACAGAGAAATACagTCTCATATATTGGTCGACGGAGTTCTCCAAGAATTACTAAACCAGTATCTTATAATGAGGATAATAGTCCTGATTCTCCATCAGTGAGTCCACCAAGACAaGATCAAGAAATAATTGCTGTagatgttacaaaaaaaattcttccaAATTTGCCTCCTGTTGGACAAATTGTAAGACCTGAACCAAGAGttggaaatatgttttatgCCATGAAATCAAATACATTTGGATCATGGACACTGTGTGAAGTTTTAGAAATAATGTCTTCAggaataaatattaatgGTAAAATATCAGAAACAATAATGTTCAGAATCAAATTTGAAAGCTCAAAAACTAAGCCatctcatttaataaaaattgtttctgCCAAAAGAATGGCATATGCAACAAAGTCTCCAGTTAGATTACATATCGGAAATAGAGTTATTGCTGTATTTAAAGACAATGAACAATCACAACGAAGAGATTTGTTCGCTGGAATTGTAGCAGAACCTTTGTCATCTCTAAATAATTTTCGatatttaatattttttgatgatgGTTATACGCAATACGTAACCCAtgacaatgtttatttatttgttgaagaAAGTACAAATGTTTGGGAAGATGTTCCACTCGAATCAAGAGATTATATTAAAGGTTACCTTAAAGAATATCCTGAAAGACCAATGGTTAAATTAACAAGAGGACAAGTTATTAAAACAGAATGGAACGGTAAATGGTGGACAGCTAGAGTACTTCAAGTTGATGGGTCATTggttttaatgtattttgatGCAGACAAAAGATCTGAATGGATTTATAGAGGATCTCGAAGATtagcacCTTTATTCAATAgtaatcaaaatcaaaaaatgcgGCAGATCAAAGGGTTTGTAACACCTCAGAGACGTTTACCCCCTAGAAAGcaAAATGCACCTTACGTTGAATACACTCGTACAACTGAATATATAGAACCTAGTGAATCTGAACAAGATCAACCAATTGTTTCAACAGCATCTCGTGCTGTTGCTAGAAAGAGTACATCAATGACTACTATTAATTTTGGGCCAAAAAATGCTCCACAAACAATTGTACCATTTTTGCCCACTACTATAACACAGCCAGCTAGTAAAGTTATTtattatGCACCACGAGCTGGTACAATTCCTGCATTATACAAACTACATCAATGTAGTCCAAATTGCAATAAATTAACAAAGCGGAAGTTGAGTGatcttaaaaattatagtcTTCTTGCAAAACCAATTCTTTCGGGTTGGTTTAGAGAATGTATacgatattcaaaaaataaacgagAGATACGTTATATAACACCATGTTCTCGTATTTTACGAACTATTCAAGAATTGCATTTATATTTGCGAATAACACAGAGTGAAATGTCTGTTGatatgtttgattttaatttttgggtACATATTCTTGCagaattttgtattgaaaaaacatatgttaatttatctGATTTATCAAATGGAGAAGAAAATGTTCCAATACCATGTGTAAATTATATAGATTGTACATTACCTGATATGTGTCGGTATACATCAAAACGGGAGCCAATGCAAGGTGTTAATTTAAATCTTGATGAAGAGTTTCTCTGTGGTTGTGATTGTACAGATGATTGTCAgGATAAAACAAAATGTGCATGTTGGCAATTAACTATACAAGGAACAatgtatggaaaaaataaagtacCTGATATGAACATTGGATATGTTTATAAACGGCTCTTAGAACCTGTCATTACAGGCATATATGAATGCAATTCTAGatgtaAATGTGCGTCAACTTGTTTAAATCGAGTTGCGCAGCATCCTTTACAACTAAAATTACAAGTTTTTAAAACTGCGAATAGAGGATGGGGAATTCGTTGCTTGAATGATGTGCCTCAGGgttcttttatttgtatttatgctGGCCAGTTGTTAACTGAACAAATGGCTAATgagggTGGTAAAAATTTTGGTGATGAATATTTAGCTGAATTAGACTACATAGAAGTAGTTGAACGATTAAAAGAAGGATATGAATCTGATGTTTCAGAAGAAGATATGGAATCAACACAAGAAGAAAGAAAAGAATCGTCACaagaagaagatgatgatgatgatgaagtaATACCTGATACTagTACACGTTTACGAAAAAGATATGATGAAACAGATAGTAATAGTAATCAAGGATCTGATTCGGAAAGAActgaaaaaaagataaaacttGACCATGATAAAAGTAAAGAAGACAGTGGAAAAAGTGAATttaaagttattgaaaataattcagaagaaaagaaaaaagataataatcacAATAATAGTAATGAACAAAAAGAAGATAAAAAACAAGAAGACAagattgaagaaaataataaacaagaatCTGAAGAAACAGTTACTGGAGGTGTCGCTGTTAAACAAGAAATGAACACTGAATCTGTGAAAGATCTGTCTAAAATAGCACTAGATGAAGATGAATGTGTTACTATTAGTGATGATGAAATGCCAGTCACTAGAGAACCTTCTAGTTTTATTCCTACTGCTTCTGctgaagaaaatattgaacattGGGAATCAAAGTATAAGTCAGTGCGGACTATATTTGGTGAATCAGAATCATGTTATGTTATGGATGCTAAAAACGCAGGAAATATTGGTagatttttaaatcACTCATGTAATCCTAACGTTTTTgttcaaaatgtttttgttgATACTCATGATATTCGTTTTCCATGGGTTGCATTCTTTGCATTAACTTATATACGAGCAGGAACAGAACTCACTTGGAATTATAATTATGATGTAGGAAGTGTTCCaggaaaaattttatattgtcagTGTGGTAGTACTGAATGTCGAGGCAGgcttttataa
Protein Sequence
MRPLAKNFATPPVIANVRLCDSYHGCRLQPALTSRGLGFLLTTVSLLNAASLHRIARDLPEKEIPKNDRISHIIRDQYKTNPEYKNNESEELDKFEALEKKNTQYENVYKSSKVSSLEDSLSHVFDQQTDETKHFRGSTKYFTTLSNLDLPTTTAKNNLVKQSNGNKLETNINLPPIKNEVGNIIQTQSSDKENVKYELNDDSEVPSTESNKKSSHVIHTSTKNAIKDINQNENVKQTGNTTNIESQNLQNDKSEIVSERTETGRSFDIDKYISPEFHNINNVYTQISSAEAERYADPNNYGEIYHSTKPFGKMFSYSITHDYDTELTTPKSTLFDRKFHQISNDIKYSLDQDENLSEKNSNQSDNIGKSPVITHLQSTTKSTEYSTEKIQNTDKPTTSLDETTFEQFEFDTTENVDRKIIRSTDTISFIETTVTSSSIPLENTLSEKETTEVYTETIPSEVNNTSQQNTFNNSEESITLGKTEKTLFSTIKTAKNLHIPKSTTEMETESTSYIVLNSDDKTTFAYISDDQSSTLSTQNTNDITTQSSIFNEFNTKPIIVTEEIINSTTPELINVSEDELTQTTTNNVNTTTLDNKSIEMTTFEIKIYASTEKLDAVSENTTSQSSEIITSTLKIESTTLNKPENEPQVTPLISKIENDDADGDGDQLENQPETNYKVNHNLQDYEDFTNEANDNQEEHQASVTNKINKNDEPSNLNNKVYKPLNTIIAPTEESTEESTTEPEENIEEELTIGTVAAIIIASVAVLCLVLLALLLIIMRKRQSRLTYGQRCTPVSLDAYSLDSVSIYNSVRRKGGIRASKRSYGNPAFEDSSTVTNPMNFAAMANFIIDKEAIMKEFEDIPQVLVENNELPEGCESKNRYANVIPLPETKVVLSLVEGDINSDYINANFVRGPKNAKSYYIACQAPMQETIDDFWRMIWEQQSRVILMLTDLVENGINMVSNCWREITHLWYIGWPERGVPEEANSIIAFLIEARSYLKVNLNSYQTNQNGQKISENGYIGEDVSGQGPVVVHCSPGTGRTGTVIACDVAIREFELLRMVDIPKTVYRIRRDRAGAVQTLEEVIDLDDSNDEDKRPSIKRPPRKCINAECTGDDTDLKVAASYCISFFKVKCNRKKKQLVCKDCRKMCLDNMQVMADMLLKREPIFDHKIPMNVDSVEIIDSDEDNTEDEKEKSTLEEKEREEINKKINKAFNKYDINFQIEWAKDKLEKDNNRNEEQLKEIDELLKQLQVKADLVRSSIYSNRPRNTELEPLDINDDYSVRVIQRNTVSYIGRRSSPRITKPVSYNEDNSPDSPSVSPPRQDQEIIAVDVTKKILPNLPPVGQIVRPEPRVGNMFYAMKSNTFGSWTLCEVLEIMSSGININGKISETIMFRIKFESSKTKPSHLIKIVSAKRMAYATKSPVRLHIGNRVIAVFKDNEQSQRRDLFAGIVAEPLSSLNNFRYLIFFDDGYTQYVTHDNVYLFVEESTNVWEDVPLESRDYIKGYLKEYPERPMVKLTRGQVIKTEWNGKWWTARVLQVDGSLVLMYFDADKRSEWIYRGSRRLAPLFNSNQNQKMRQIKGFVTPQRRLPPRKQNAPYVEYTRTTEYIEPSESEQDQPIVSTASRAVARKSTSMTTINFGPKNAPQTIVPFLPTTITQPASKVIYYAPRAGTIPALYKLHQCSPNCNKLTKRKLSDLKNYSLLAKPILSGWFRECIRYSKNKREIRYITPCSRILRTIQELHLYLRITQSEMSVDMFDFNFWVHILAEFCIEKTYVNLSDLSNGEENVPIPCVNYIDCTLPDMCRYTSKREPMQGVNLNLDEEFLCGCDCTDDCQDKTKCACWQLTIQGTMYGKNKVPDMNIGYVYKRLLEPVITGIYECNSRCKCASTCLNRVAQHPLQLKLQVFKTANRGWGIRCLNDVPQGSFICIYAGQLLTEQMANEGGKNFGDEYLAELDYIEVVERLKEGYESDVSEEDMESTQEERKESSQEEDDDDDEVIPDTSTRLRKRYDETDSNSNQGSDSERTEKKIKLDHDKSKEDSGKSEFKVIENNSEEKKKDNNHNNSNEQKEDKKQEDKIEENNKQESEETVTGGVAVKQEMNTESVKDLSKIALDEDECVTISDDEMPVTREPSSFIPTASAEENIEHWESKYKSVRTIFGESESCYVMDAKNAGNIGRFLNHSCNPNVFVQNVFVDTHDIRFPWVAFFALTYIRAGTELTWNYNYDVGSVPGKILYCQCGSTECRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-