Basic Information

Insect: Neoceratitis asiatica
Gene Symbol: egg
Assembly: GCA_030068015.2
Location: CM061527.1:3363220-3368921[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.3e-13 5.5e-10 39.0 0.0 5 75 973 1036 970 1038 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.3e-13	5.5e-10	39.0	0.0	5	75	973	1036	970	1038	0.90

Sequence Information

Coding Sequence: atgtctgataatataaatatagttGATGAAgatgtaaaagtaaatgaagaaaatttggctgaaGAAAAATTAGTCAGTGGTCAATCTGGCGAAGAGGAGAAATCCCATGTGGATGATGCCAAACCCTTTAAGGAAAATGTTAATTCAAATGTAGAAAATATCAATGATCCGAATGAAGAAGTGCATAAAAAAACGACAGAAACTAAATCGATCATTAAAAATGCAAGTGTAACAGAATTACAAGAAAACAAAAGCCCTGCAACGATTTGCAAAGGGAAAGGGGTTGAAATAGCGGAAGAGTCAGATATGGAACCTGAACAACAAGAAAACAATAGTACTGAATCTAATAAATTAACTGATCAAATACCTGAAAGTACATCACTTACAGATATAGAAGGAATAGCAGAGAAAGAATTGGATTCCGAAATAAATGAATTGGGGCCTAATAAAACAAGCAGCGCTAATACAGGTGATCCAATGGAAATTGATAACCATAGCTTGGATGATAGTGGCGGAAATGATGATAGTCAAGAATCGTTACCACTTGTAATTGATGAAAAACCTGTTTCGCCTAAAGAATCCAATGAAAATGACGAGCCTTCAAGTTCTCTTCTTGAGAATAGCCCAACAACTAAAAACATTGGGGAAGAAGAGCTTATAGAAGGTAACAGTGGTTTCAGTGTGGCTACACAAATTGATCAAAATGCAAAGGTTATAGATAGCGCTACGAACAAAACAGAAGATCAAGGAGCACCTGAAAATATAATCGAAATAGATGATGAAAATGAAGAGATTAAGCTGGACGAAGATCCTGATGTAGAAATTACTGCTACAAGAAGTCCATCTTACATTccaatcattgaaattgatgatgatgatgatgaagatgaaaTAGATAAGGATAAAAAGGCTGCCCAAAATAGTGAGAATAAAGACGAAAAAGCTATTTCCAGAACTGATACCGAAGCAACTGCGCTACTTAGTGAGACTAGTAAAAGCACCATTTATAAAGAAGATAATGAAGAAAGAGCAATTGAAGATGTCACAATGAAGGATCCATCTGAAACAAATCCAGTCACGGAACAGACAGACTTGTTGAAGTTAACCGCATTAAAACCAGATGCAGACGAACCATCCAATGTTGAACAAACTAATTACGAAGACAGGGTCGATGAAGTATTTTATAATCAAGAATGTATTAATCATGATTGCCCTCACAATCATAAGCAATTTTTCTTAGCACCACTATTTGCTTTGAGCCACTTTAAAGTCAAGAAAAGACGCAcccaaaaacaatatatttgctCAGAATGTTTCGACTGCGCACTTGATGGATATGAGgaatattGCGGTTTATTAAAGGCAAAACAACCTTTacttttgaaaaagataacagTACAAGGACCAGAGTTCGTGGAAATTACCGACAGCAGTGACGATGATGAAGAAACGTCGGCAACACAACAAATTCAAACAGACAAAGCAAAAGGTTCCTTTTCCAAAGCTAGTTTGGATCTAATAGAAGCAGAACTTGAAAACTCTATTAAAAATGTGCTTGAAAAGCTCGATATTCAAAGCCAGTTGACATGGTCAAAGACAATTTTAGAGACACGTGCTCGTCGACTTGAGGAGGAATCTGACTTAAATGACAAATTATTACGCTCATTACAGAAGAAGGCTGATCAAATGTACAGCTCACTTTATCAATGTCCAAAAATTAGGTTGCGCCAGTTTCAACCATTGGATTTGAATACAAATTTGCCATATAATTTCCCTGAAATAACACCATGTCCACCAGTTGGTGAAATAATGCGCCCACCAATAGAAATTAATCAAGTCTACTACGCGGTAAAGAATAAAGCAATAGCCAGTTGGGTCCCTTGCAGAGTCATTGAGCAGATGGAATCTAGCTCAATCTTAGGCACACATACTAGGGTGCCCAAttataaagtgaaatttttaaggCTACAATACCAGATGGTTAAAACTGTAACGGCGAAACATTTGGCATACTTTGATCCACCTAAATTTCGACTCCCAATTGgtTCACGTGTAATCGCTTACTTCGATGCCACCTCCTTGTCTCGTGGCAAAGAAAAGATGATGATTCAAAGTGCTTTTTACCCAGGCATTATTGCTGAACCTTTGAAACCCAACAATAAATATCGttatttaatATTCTATGACGATGGTTACACACAGTATGTTTCGCACAAGGATGTTCGTTTGGTGTGCAATGTTTCTGAACATGTGTGGGAGGATGTTCACCCTGCATCGCGtgaattcatacaaaaatatttaacgcAGTATTCGATCAACCGACCAATGGTTCAAACACAAAAGGGACAAAGTATGACAACTGAGTCGAATGGCAAATGGATATATGCACGAGTTGTTGATATTGATTGCAGTTTAATACAAATGCAATTTGAAGGTCCAAAAAGCCATACCGAATGGATTTATAGAGGCTCACTGCGATTAGGACCAGTATTTAAAGAATATCAGAAAACACTGCAAAAAGATACGTTGCCCATACCACGACTAGCTAGACGTACCGAACCATTTATACGTTATACAGCTGACGAGGAAGCAACAACGGCGCAACAGGAGCAAGTAAAGGAACGTGAAAGGGAGCAACGTGTGACTTCTAATGAACCACGTGCTGTAGCTAAAAAGAGCGTTAGTCGTTTATCAACAGATTCAACAGCAACATTAAGCAACATATCCTCGTCAACAACATCGTTACCAACGGTTCGACACTTGAACAACTCCACGATTTATCTTGAAGATGAAAACAAGCCAAAAGGAAAAGTTGTTTACTATACTGCGAAACGCGATTTACCACCGTTAATATATCGGCCACATAAATGCTCACCAACATGTCTTTTTAAAATACCGCACAATCTTAGCGCCTACAGTCCGTTGTCAAAACCTTTACTCTCTGGTTGGGAGCGACCCATATTACGTCTTAAGAGCAAAAAAATCGTCGCTTATCGTGGACCGTGTGGTAAAATTATGCGCAACATGGAGGAGGTACGTCGTTACTTACGTGCAACAGAAAATGCGCTTAATGTGGATAACTTTGACTTCCACCATGAGACCAGCTGCTTGGCTGAATATGTGATTGAGTCAGCTATAGTGCAAAAACGCGATATATCCGGTGGTCAGGAAAAAATGGCTATACCGTTGGTTAATTACTATGACAATACACTACCACCTGAATGTAAATACGCTGCACAACGTATTCCTACCGATGGTGTAGACATAAATCTGGATCCAGAATTCCTAGTTGGATGTGACTGTGAAGATGACTGTTCGgaTAAATCGAAATGTTCCTGTTGGCAACTCACCTACGCAGGTGCTAAATATGGCAATCCAAACACACCAATGGAGGAAATTGGTTATCAATATAAGCGTTTATATGAACATGTTCCAACGGGAATTTACGAATGTAACTCCAGatgtaaGTGCAAGTCCAATTGCTTGAATCGTGTAGCTCAGCAGACTCTAGCAATGAAATTACAAGTATTTAAAACGTCAAATCGTGGATGGGGCTTACGTTGTATAAACGATGTGCCGAGAGGCAgctttgtatgcatttatgctGGTCACTTGCTAACCGAAGCTAAAGCcaatgaaGGCGGTCTAGATGCTGGTGACGAATACTTTGCAGAATTGGATTATATAGAAGTTGCAGAACAAATAAAAGAGGGATACGAATCAGATGTTGAACCCCCAGGGATTGAAGAAGAAGagGACGCCTATGCGCCAGATCCAGAGGATGATGATGAGTTCACACCGAGTAAGTCATTTTTAACTCGTGCCaaaaataaagcacaaaaacTTACACGTAGTAGTTCAACACAGAACACAGACGAGGACTCGCAGGAACGacaagtaattaattttaatccaaATGCTGATATGAATGAAGACTCCGCACGAGAATCCTCTATACGGGCTTTGTTCGGCAAGGATGAGGCTTGCTATGTAATGGACGCAAAAACTATAGGAAATCTTGGGCGTTATTTCAATCACTCTTGCTCTCCGAATCTCTTCGTACAAAACGTATTCGTGGACACGCATGATCTACGTTTTCCGTGGGTAGCATTCTTCTCGTCCACGAATATTCGGGCAGGCACTGAACTAACTTGGAATTATAATTATGAAGTAGGCGTTGTGCCCGGGAAAGTACTGTATTGTCAGTGCGGTGCGCCGAATTGTCGGCTACGTCTCCTCTAA
Protein Sequence: MSDNINIVDEDVKVNEENLAEEKLVSGQSGEEEKSHVDDAKPFKENVNSNVENINDPNEEVHKKTTETKSIIKNASVTELQENKSPATICKGKGVEIAEESDMEPEQQENNSTESNKLTDQIPESTSLTDIEGIAEKELDSEINELGPNKTSSANTGDPMEIDNHSLDDSGGNDDSQESLPLVIDEKPVSPKESNENDEPSSSLLENSPTTKNIGEEELIEGNSGFSVATQIDQNAKVIDSATNKTEDQGAPENIIEIDDENEEIKLDEDPDVEITATRSPSYIPIIEIDDDDDEDEIDKDKKAAQNSENKDEKAISRTDTEATALLSETSKSTIYKEDNEERAIEDVTMKDPSETNPVTEQTDLLKLTALKPDADEPSNVEQTNYEDRVDEVFYNQECINHDCPHNHKQFFLAPLFALSHFKVKKRRTQKQYICSECFDCALDGYEEYCGLLKAKQPLLLKKITVQGPEFVEITDSSDDDEETSATQQIQTDKAKGSFSKASLDLIEAELENSIKNVLEKLDIQSQLTWSKTILETRARRLEEESDLNDKLLRSLQKKADQMYSSLYQCPKIRLRQFQPLDLNTNLPYNFPEITPCPPVGEIMRPPIEINQVYYAVKNKAIASWVPCRVIEQMESSSILGTHTRVPNYKVKFLRLQYQMVKTVTAKHLAYFDPPKFRLPIGSRVIAYFDATSLSRGKEKMMIQSAFYPGIIAEPLKPNNKYRYLIFYDDGYTQYVSHKDVRLVCNVSEHVWEDVHPASREFIQKYLTQYSINRPMVQTQKGQSMTTESNGKWIYARVVDIDCSLIQMQFEGPKSHTEWIYRGSLRLGPVFKEYQKTLQKDTLPIPRLARRTEPFIRYTADEEATTAQQEQVKEREREQRVTSNEPRAVAKKSVSRLSTDSTATLSNISSSTTSLPTVRHLNNSTIYLEDENKPKGKVVYYTAKRDLPPLIYRPHKCSPTCLFKIPHNLSAYSPLSKPLLSGWERPILRLKSKKIVAYRGPCGKIMRNMEEVRRYLRATENALNVDNFDFHHETSCLAEYVIESAIVQKRDISGGQEKMAIPLVNYYDNTLPPECKYAAQRIPTDGVDINLDPEFLVGCDCEDDCSDKSKCSCWQLTYAGAKYGNPNTPMEEIGYQYKRLYEHVPTGIYECNSRCKCKSNCLNRVAQQTLAMKLQVFKTSNRGWGLRCINDVPRGSFVCIYAGHLLTEAKANEGGLDAGDEYFAELDYIEVAEQIKEGYESDVEPPGIEEEEDAYAPDPEDDDEFTPSKSFLTRAKNKAQKLTRSSSTQNTDEDSQERQVINFNPNADMNEDSARESSIRALFGKDEACYVMDAKTIGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFSSTNIRAGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00303806;
90% Identity: -
80% Identity: -