Basic Information

Insect: Neoascia interrupta
Gene Symbol: pol_2
Assembly: GCA_947623515.1
Location: OX392463.1:145797802-145813051[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.052 7.6 8.2 1.7 1 23 1531 1553 1531 1553 0.96

2 8 0.14 20 6.8 4.4 1 23 1561 1584 1561 1584 0.96

3 8 0.0006 0.088 14.3 2.4 3 23 1615 1635 1614 1635 0.97

4 8 2.6e-05 0.0038 18.6 0.5 1 23 1641 1663 1641 1663 0.98

5 8 0.045 6.5 8.4 0.2 2 21 1670 1689 1669 1690 0.93

6 8 0.0068 1 11.0 3.5 3 23 1915 1935 1913 1935 0.96

7 8 5.4e-05 0.0078 17.6 0.3 1 23 1941 1963 1941 1963 0.98

8 8 0.0006 0.087 14.3 0.2 2 23 1970 1991 1969 1991 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.052	7.6	8.2	1.7	1	23	1531	1553	1531	1553	0.96
2	8	0.14	20	6.8	4.4	1	23	1561	1584	1561	1584	0.96
3	8	0.0006	0.088	14.3	2.4	3	23	1615	1635	1614	1635	0.97
4	8	2.6e-05	0.0038	18.6	0.5	1	23	1641	1663	1641	1663	0.98
5	8	0.045	6.5	8.4	0.2	2	21	1670	1689	1669	1690	0.93
6	8	0.0068	1	11.0	3.5	3	23	1915	1935	1913	1935	0.96
7	8	5.4e-05	0.0078	17.6	0.3	1	23	1941	1963	1941	1963	0.98
8	8	0.0006	0.087	14.3	0.2	2	23	1970	1991	1969	1991	0.95

Sequence Information

Coding Sequence: ATGAGTCGGCCGTCTAATCCTGGAACCAATATATTAACCAAAGTAACCACTGAGCAAGAGTTCGATCGTTTTTGCAAGTCAATCAACAATTTTAGTTTTGACAACTCCGCGAGTTCAGCCGCGAGCAGTGCAAAAATGGTTGACGAAAATCCGTCAGATGAAAATCCCACTGATCAGGGAATAAATAATATTTCGCCAGTGGAAGCTTTAGCTTCGAAAATTGAGCAGACCTTAACGGTCAATCAAATCCATCTCTTCCAGCAGATGGAAACCTTTATGAATGGTATGTTGGAGAAAGTCAATGCTTTGTCAGTTGTTCGCCCAAGTCCACAAGGATCTTATCCCAGCAATAGTAGTAGCGTCCAGCCTGTGAGTGATGCCAATGGTAGACATTCCGGCGCTTATTTCCTCCCATCTGATTTTAACCCAGCAAGACCTCCTCCAAGAGAAACGCAAAGCGTAGCCAACTCCATGGCGTCGGAGATTGTGCGGTTGGACAGGTGGAATGTAAAATTTGAGGGACAAGAAAACGTCGTAGACTTCCTGTTTAAAGTTGATAGGCTCCAAGCCTTGTCGTCCTACACGGATGAACAGGTCACAGCAAACTTCCACAGTCTTTTGGGTGGAAAGGCTAATGACTGGTACTGGTCATTTTTGCGAAAAAACCCTCATACAAGGCTTGGAGAGATCAAAACTGCTATGAAGAGGGAGTTTGGGCGAAAGGAAAACGATGTCGACGTATACATGAGATTGCTCACCCGCAGGCAAGGATTTAAGGAGAGCTTCGACGACTTTTATGGCTCCATCGTAGGTCTGAACGACCGCCTGAACGATCCATTCGACGCCAAAAAGTTAGTCGAAGTTATTAGAAATAATTCAAGAGATAAACTGGGAGAGATATTACTGTCTTCCAGCATATGCGACTTGGAGCAGTTACGCCATAAAGGCAGAGAAGCAGAACGGTTTCTGGCAAGGCGAAACTTTAGTCAGCGCTCTGTTCAAGAGCTCCATCTGCCGGAAGAGGAGGATGAGGAACTAGTAGCTGGTGAAGTAGCAGCGATGAGTAGGCCTGAGGGAAATCGGCCATCAAACTCTCTTGTTtgctggaactgtgacgttaaagaggaacgacaggacagtcggggacagtcgttcCAGCAACTTCCCCGAAAGGCAGAAGTAGAACCTTTAAACGGGTCTGGATGTAGGAGTCAGGTGTCGAATAGTCCAGCGGTTAAGATTCTTCAGCGAAACCAGGAACCAATTCCATCCAGTCATCCTGCAAACAAGTTTGCTCTAAAGACGCTTCATGAAAGGAAGCAGAAATATTATGAGTTGCGCGCTAAGATTATGGGTGGAGGAATGGGTAAGACCGGATCACTGTCTAAGTGTAGGGAGCGGTTTCGAAAGCGGAAACACTTTCGAAAACTCATTGTCGAGACAATCTTAGCTTCCGAAATAGACGGTCGGATGTACGCTAGTGTTCGTCTCAAGGATGAACAAGTCCTTGGACTGTTGGATAGTGGTGCATCCATCTCTGTTTTGGGAGAGTCAGGGTTGGAATTCATAGAAAGGAATGGGATTCAGATGAGGCCATACAATAATGTGGTGAAGACCGCAGATGGAGGCTCACATAAAATTGTCGGCTTTTGTCAAATCCCGGCTACGCTGAACAAAGTGACTAAGACCATTACTTTCTAtgttattccaaacctgacacaaaaagtttatctcggcatggatttttggaaggagtttgaactgatgccacaggtctctgcactggacgagcctacacttagagaggaggaaaatgtggattcacaaggggaccctagtttcatggtacttacaccagagcagcaaactaagctagagtcggtgaagaagcaatttccaaatttcgcagacaagggtctcggtcgtactcatctcgaaacccatgtaatcgatgttggcggagcagtgcccattaaatctaggcactaccccctgtctccggttcggcaggaagaggtttacaaggaactcgaccgtatgctagaacttggtgtgattgaagaaagcaactctgcttggtgttccccgatagttctagtcaggaagccaggcaaagtacgcctctgcttggatagcaggaagttgaacaaggtgacaaagccggatgcatatccgcagccacttatagacggattactcggtaacttggaggacacattctttatctctgggcttgatctcaaggatgccttttcgcaaatacctcttgagaaagagtccagagagaagacagcatttgcagtaccaggacggccattataccagtttgttgtaatgccgttcgggttatgcaatgctgcccaaagaatgtgtcggctgatggaccgagtaatgagcgttctacctccccgcttgcgcaaacacgtaatcaaatacatcgatgatcttctgatttgtacaccggatttcgacacccatatccaagttttggcagaagtggcttcctgcctgcgtagggcgaacttaacaatcaacgtaaacaagagcaagttctgcatgcgggagattaagtttcttggttacatcgttggtcagggtaacctcaagaccgatcccgaaaaggttgccgcgatggtagaatttccaattcctaagaccgtgagacaggtgcggaggtttgtaggcatgactgggtggtataggcgattcatcaagaattactccgatctttcagctccactaaccgattgccttaaaaagcgaaagggcttcgagttgacatctgcggcagaagaggcggttaagaagttgaaggaggcacttacatgcgccccagtcttatcacagcccgacttcaagaaggaattcattattcagagtgacgcttcttctgaagcggtaggcggggtgctttgccaacaagacgaagatggaaacgagaagcctatagcttttatgtcaaaaaaacttactaaagcccagaaaaattttacggtgactgagcttgagtgtctggcggtgttgttaagtgttagaaagtttcgtgcctacattgatggtttaccatttcgagtcataactgatcactccagtcttaagtggcttatgtcacttaaagatttgggcggaagactggcacgttggagtctcgagctccaacggtttacgttcgagatcgaacatcgcaagggatccctcaatgtagtgccggatgccttgtcgagaggacatatggaagagatttcggtcacgatggtaggtgaggatatagatttgtcttctgctgagtttgactctgaggagtatggtagacttcgagaggacattgagaagaatcaagcctcacttccggatctcgttgtatccgaaaagtttatatacaaaagagtgaggttcagaagtggggatcttgaaaacgaggattcactttggcggctttgggtgccgcacaccttgacacaaacgcttataggaatgaaccacaacaccaagttaagttgccacggtggttttcttaaaacttataaccgcataaaggaaaagtactactggccgaaaatggcttctgaaattaaaacgtttgtgagccagtgcgaggtgtgtaaaaccacaaagtcgtcaaatcaaattcttcgtcctccgatgataaaccagattctctcagagcgacccatgcagaggttgtacattgatttgcttggcccataccctcgcaccaagcgtggaaatatcttcatctttatcgccattgaccatttctctaaatatgtcttcctcaaggcgctttctaaggcaacaacgtcaaggataatctcattcatggaaaccgatatttttcatgcctttgggactcctgagtttgtccattcggataatggcaaacagttggtttcttcagaattcaaaaggttcgtggacagctatggcgttcggcatattcgaacggcattctactctccacaggccaatgtatctgagagagtcaacactagcatcctcaacaagcttcgtgtattcgtggacgatgaacaaaatacgtgggacacccatttgtccagtatagcgtgcgctttacgtgccgacacccatggttccattggttgtcagccctattacgccctattcggccaaaatatgatcaaccatggatcatcgtacaCAATACTTCGAAGCTTGAAAGCACTTGGGGATCCAGATATATTGGTCACACCACGCGAGACGACGAtggagatcgcacgtcaaaagttgtccaggaacctgctgaaggcgcatTCTATTGACAATGTTGAATCTAAGGTTAAAATTAAGCAAATGATGGAAACCTTAACCGGTTTAGAGATAAACCCTAGCGACCAATTACCCAAGAATATTTGCAATGATTGCAAGAAGCAAATTCAAGCGGCATATAAATTCCGTGTTAATAGCCAAAGAATCGATCGATTATTCAAAGGTTACCTTACGCAAGTCTATCCCGAACAAAAAAGAAATGAAGAAGATGAAGACGCTTCGGACGATACATCGTCTCAAATGTCCGAAGATAAAACCATCGATGAGCAAACAAAAGATGACAAAGACTTAGATTTATTTGCCTTCGAATGTAATATATGTCATTTGTATTTTCCTGAGAAAAGAGATCTCGACCAGCACAAAGTAAAGCATGATGGCTCACAGAAGCACGTATACAAATGTGGAAAATGTTTTAAGGAATACAAGTATCGCAATGGCTTACATTACCATTTGGAATCTTATCACCTTCGAGCTAAAGAATATAAATGTGAACAATTCGAATTAGAAGCTGACTTTTGCGGCCACATCATAAAAACACATTACGAGGAAAAGATTTGCCCCCACTGCAATAGATTCTTTAATCAAGCACTATATCTAGAAGCTCATTTGCGGCATCACAATGGCGAAAAATCCTTCGTGTGTCCACTTTGCTTAAAAGGATTTTCGTCTAGTCGATCTCTGCGCAATCATATAAAATTGCACGCCGAACGAGAGTCTTGTTCTTGCGGCACTTGCGGAAATGTGTATGTTTCACACATAGATCTTATAGCCCACATGAAGGAATACAAAAATACTTGTAAAAGTATTGCAGATGAGAGTCTATCAAAGGCGCAAATAAAACAGTTAAAGAGCCCAGATCTGTTTAAAGAAGTTTTAAAAACGGAACCAAGTGAACGTGCTTTTCAAATGAAAGACTCTTTGGTTGAAACTGCTATCTTCAGTATAAAGCATATTGATGAAGATATGGAACAACCTAACGAGAAGCAAGGAAGTTTGATTGCGGTGCATCCATCAATCAAAGTTGAACCCAAACCCAGTGCTCTATTGCTTGAAGACTCGGACGAAAAAGCCATATTTGCTATCAAACGTATTGATACCGATCAAAAAACTCTGTTAGATGACTATAAAACCACAAGTTTGCCATCAATTAGTGCCAAGTACAATTTGACACAAGAAGTTGACAGACTTGAACCAAGCAGTGCAATCGAACAACACAATTCTAGCGGCCTTGAGATAAAAATAAAACAAGAAAAGCCAGATGAATGTCAAACGGTTCATGAAATAGCCAACGAACCGGTTAGTGATGATGACATGTTGGAAAAAAGTTCGGATCCTGACAAAGCACCATTAAATGTCGAACCTCTAACATGTGCAATTCCTGGATGCGATTTCGAATGTGAGTTAGAAGAAGATTTCTTCAAACATATCGCAAGAGAACACTCCAAAGAGAGTAACTGTCCTTACTGCATTAGGACATTTAATCAATCACACAACTTGGAAGGACACTTGCGACATCACAACGGCGAAAAACCCTTCACCTGCCCACTTTGCTCAAAAAGTTACCCTTCAGGTCGGGCTTTGCGAAGGCATATAAATATGCATTCGTTCCAGGATGGTTTGTCATGCAACTTGTGCGAGGAAAAATTTGTCACTCAAAGAAATCTTGCCAACCATGTGCAGGCGCACAAGAATGGATGTAAAAATGATTCTAAATCAAAGGAATACCAACCGAAGGAACCTCTAGGTGCAGAAAAAGTATCGGACATTTCGAATTGTAAAGAAACTGTTAAGGACGAACCTGGTATAACTTTGTTTCAAATAGAGGGTTTGCCTCAGAAAAGTGTGTTCAGTATCGAATTCATTGATGATGTTGACCAGAAAGATCGAATAAAATCTGAACAAGTAGCCTCTGATTTACCATCGACCAGTGGACCCTACTCATTGCTACAACGTGATACTATCGCCGATAAAACTTTTGATCTAACCATAAAAGAGGAGAAACAAGATGAAACTGAAGTTGATTGTGAGGTCATCAATGAACCAGTTAGTGATGATGACCAGTTAAAACAAAATACCATATTCGGAGAACAGTTGGCCGACTCTGATAACATTTCTAAATGTCCAGTTCCAGGATGTGCTTTTGTATGTCCTACTTTTGTATTTTTGTGA
Protein Sequence: MSRPSNPGTNILTKVTTEQEFDRFCKSINNFSFDNSASSAASSAKMVDENPSDENPTDQGINNISPVEALASKIEQTLTVNQIHLFQQMETFMNGMLEKVNALSVVRPSPQGSYPSNSSSVQPVSDANGRHSGAYFLPSDFNPARPPPRETQSVANSMASEIVRLDRWNVKFEGQENVVDFLFKVDRLQALSSYTDEQVTANFHSLLGGKANDWYWSFLRKNPHTRLGEIKTAMKREFGRKENDVDVYMRLLTRRQGFKESFDDFYGSIVGLNDRLNDPFDAKKLVEVIRNNSRDKLGEILLSSSICDLEQLRHKGREAERFLARRNFSQRSVQELHLPEEEDEELVAGEVAAMSRPEGNRPSNSLVCWNCDVKEERQDSRGQSFQQLPRKAEVEPLNGSGCRSQVSNSPAVKILQRNQEPIPSSHPANKFALKTLHERKQKYYELRAKIMGGGMGKTGSLSKCRERFRKRKHFRKLIVETILASEIDGRMYASVRLKDEQVLGLLDSGASISVLGESGLEFIERNGIQMRPYNNVVKTADGGSHKIVGFCQIPATLNKVTKTITFYVIPNLTQKVYLGMDFWKEFELMPQVSALDEPTLREEENVDSQGDPSFMVLTPEQQTKLESVKKQFPNFADKGLGRTHLETHVIDVGGAVPIKSRHYPLSPVRQEEVYKELDRMLELGVIEESNSAWCSPIVLVRKPGKVRLCLDSRKLNKVTKPDAYPQPLIDGLLGNLEDTFFISGLDLKDAFSQIPLEKESREKTAFAVPGRPLYQFVVMPFGLCNAAQRMCRLMDRVMSVLPPRLRKHVIKYIDDLLICTPDFDTHIQVLAEVASCLRRANLTINVNKSKFCMREIKFLGYIVGQGNLKTDPEKVAAMVEFPIPKTVRQVRRFVGMTGWYRRFIKNYSDLSAPLTDCLKKRKGFELTSAAEEAVKKLKEALTCAPVLSQPDFKKEFIIQSDASSEAVGGVLCQQDEDGNEKPIAFMSKKLTKAQKNFTVTELECLAVLLSVRKFRAYIDGLPFRVITDHSSLKWLMSLKDLGGRLARWSLELQRFTFEIEHRKGSLNVVPDALSRGHMEEISVTMVGEDIDLSSAEFDSEEYGRLREDIEKNQASLPDLVVSEKFIYKRVRFRSGDLENEDSLWRLWVPHTLTQTLIGMNHNTKLSCHGGFLKTYNRIKEKYYWPKMASEIKTFVSQCEVCKTTKSSNQILRPPMINQILSERPMQRLYIDLLGPYPRTKRGNIFIFIAIDHFSKYVFLKALSKATTSRIISFMETDIFHAFGTPEFVHSDNGKQLVSSEFKRFVDSYGVRHIRTAFYSPQANVSERVNTSILNKLRVFVDDEQNTWDTHLSSIACALRADTHGSIGCQPYYALFGQNMINHGSSYTILRSLKALGDPDILVTPRETTMEIARQKLSRNLLKAHSIDNVESKVKIKQMMETLTGLEINPSDQLPKNICNDCKKQIQAAYKFRVNSQRIDRLFKGYLTQVYPEQKRNEEDEDASDDTSSQMSEDKTIDEQTKDDKDLDLFAFECNICHLYFPEKRDLDQHKVKHDGSQKHVYKCGKCFKEYKYRNGLHYHLESYHLRAKEYKCEQFELEADFCGHIIKTHYEEKICPHCNRFFNQALYLEAHLRHHNGEKSFVCPLCLKGFSSSRSLRNHIKLHAERESCSCGTCGNVYVSHIDLIAHMKEYKNTCKSIADESLSKAQIKQLKSPDLFKEVLKTEPSERAFQMKDSLVETAIFSIKHIDEDMEQPNEKQGSLIAVHPSIKVEPKPSALLLEDSDEKAIFAIKRIDTDQKTLLDDYKTTSLPSISAKYNLTQEVDRLEPSSAIEQHNSSGLEIKIKQEKPDECQTVHEIANEPVSDDDMLEKSSDPDKAPLNVEPLTCAIPGCDFECELEEDFFKHIAREHSKESNCPYCIRTFNQSHNLEGHLRHHNGEKPFTCPLCSKSYPSGRALRRHINMHSFQDGLSCNLCEEKFVTQRNLANHVQAHKNGCKNDSKSKEYQPKEPLGAEKVSDISNCKETVKDEPGITLFQIEGLPQKSVFSIEFIDDVDQKDRIKSEQVASDLPSTSGPYSLLQRDTIADKTFDLTIKEEKQDETEVDCEVINEPVSDDDQLKQNTIFGEQLADSDNISKCPVPGCAFVCPTFVFL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01045128;
90% Identity: iTF_01045128;
80% Identity: iTF_01045128;