Basic Information

Gene Symbol
Aef1
Assembly
GCA_963978885.1
Location
OZ022263.1:75330513-75330956[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0099 1.4e+02 4.9 0.1 19 46 15 42 8 45 0.87
2 4 1.7e-06 0.024 16.9 0.1 21 51 45 75 42 76 0.88
3 4 0.0031 43 6.5 0.1 21 51 73 103 71 104 0.87
4 4 9.7e-05 1.4 11.3 0.1 21 46 101 126 99 131 0.90

Sequence Information

Coding Sequence
ATGTCTCGTGCATTAAGCAACACAATGGCTATTACTAACAACAGCACATTGGATAAACCGTTCCAGTGCAGTGTGTGTGAGAGGCGCTTTAGACAATTAAGTACCCTGACGAATCACATAAAAATTCATACGGGAGAAAAGCCCTACAAATGCCCTGTTTGTGAGAAACATTTTCGCCAGTCAAGTACTTTGactaaccatttaaaaatacaCACGGGAGAGAAACCATTCGATTGCACTTATTGTAGGAAGCAATTCCGACAGCTGAGCACACTTACCAATCATCTAAAAATCCATACAGGCGAAAAACCTTTCGAATGTATTATTTGCAAAAAGCAGTTTCGTCAGTCTAGTACACTTAATAATCATATTAAAATTCACATGACCGACAAACTTTACCTGACTTGTACACCGGAAATAAAAGCAGAAGTAGAAGAAGCATGA
Protein Sequence
MSRALSNTMAITNNSTLDKPFQCSVCERRFRQLSTLTNHIKIHTGEKPYKCPVCEKHFRQSSTLTNHLKIHTGEKPFDCTYCRKQFRQLSTLTNHLKIHTGEKPFECIICKKQFRQSSTLNNHIKIHMTDKLYLTCTPEIKAEVEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00203877;
90% Identity
iTF_01044246;
80% Identity
iTF_01044246;