Npan072493.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nemotelus pantherinus
Gene Symbol
ZNF219
Assembly
GCA_963978885.1
Location
OZ022266.1:65565398-65569202[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.0085 2.3 11.0 2.7 1 23 106 128 106 128 0.97
2 20 4.1e-05 0.011 18.3 0.2 1 21 134 154 134 155 0.94
3 20 1.2e-07 3.1e-05 26.3 0.7 1 23 166 188 166 188 0.99
4 20 7.8e-07 0.00021 23.7 2.7 1 23 194 216 194 216 0.99
5 20 0.004 1.1 12.0 2.3 1 23 222 244 222 244 0.97
6 20 1 2.7e+02 4.4 1.0 1 20 251 270 251 272 0.89
7 20 0.096 26 7.7 1.3 1 22 294 316 294 318 0.90
8 20 7.4e-05 0.02 17.5 3.6 1 23 324 346 324 346 0.97
9 20 0.00013 0.035 16.7 2.5 1 23 352 374 352 374 0.98
10 20 0.0087 2.3 11.0 3.3 1 23 387 410 387 410 0.98
11 20 4.7e-05 0.013 18.1 1.2 1 23 416 438 416 438 0.98
12 20 0.0073 2 11.2 3.4 2 23 445 466 445 466 0.97
13 20 0.61 1.6e+02 5.2 1.3 1 19 472 490 472 492 0.81
14 20 0.87 2.3e+02 4.7 0.2 1 21 505 526 505 529 0.88
15 20 2.2e-06 0.00058 22.3 1.7 1 23 536 558 536 558 0.96
16 20 0.089 24 7.8 2.4 1 23 564 586 564 586 0.94
17 20 0.00018 0.048 16.3 5.5 1 23 599 621 599 621 0.97
18 20 1.4e-07 3.7e-05 26.1 0.9 1 23 627 649 627 649 0.99
19 20 0.2 52 6.7 1.5 1 21 675 695 675 696 0.94
20 20 7.2 1.9e+03 1.8 0.0 8 20 716 728 708 730 0.87

Sequence Information

Coding Sequence
ATGAGTGGTTTATGTAACTTGCCTCCTCAATCCAACAGTATTTTATCCATAAAAGAGGAAATTGAAATCGGCGAAAGGCAATTGCAAGAGCAGATTTTCCATGAATGCGAAGTGAAACAGAGTGGTGCTGATCAAAGCGCTAATTTCGGGAAACGGAGTGGAATTATCAATAGTCTATGCGACGATGCCGAAGATGCTCAACCTGGATTAAAGGATTGTGAAATGAAAAGTGGGACGATTAAGGAACAACTCTTTGAGCACAACTTAAGTTCGAAAAATTCTATTAATTCAACTCAAATACTCCGAGAAAAGAATCACACTTGTTCGATTTgtgcaaaaaaatttaggtggcGTTGTGAACTGGAAGCGCATATGATCTCTCATTGTGGTACTCGACCGTATGCATGCACAATATGTCCTAAACGCTTCACCGCTGCCCGTAGCTTAAACAGACACATGTTCACTTGTGGCGATAATGGAAAGTTTCGTTCCAGATACAAATGCACAGTATGTGAAAAATCTTTTTCTCGAAGTGAAGGATTAAACAGTCACATGAATATTCATCGTGGCGAACGTCCTTTCAAGTGTGATATCTGTAACAAGTCGTTTGCGAGGAAAAGCACGCTCTATTCACACAATAGGACACATTCACGTGACAAGAAATTTGAGTGTGCATTGTGCaataaaacattcatttacGCTTCGAATCACCGTAGGCACGAAAAGTTGCACTCCAATGGCCGTTTGAAATATCAATGTGATATATGTAAACATTATTTTTGGTCCGATTATCAGTATCGTAGCCACTTGGAAGGTAATAAGTGTAAAGGAAATCCGCAAGAGTCCAATATGCACACGGTCCGCGCCACAGAAACGCGATTTCAATGTTCTAAGTGTGATCATGAGTCATTCGCAAGCATTGAGCTTCTCAACCGGCACAAAGTTCAAAGTCATCTACCCTCGAAAACTCACTCATGCTCAGTTTGTGGAAAAGCATATACGCATAAATTTCGGCTTGAGATCCATATGAACTCTCATACTGGCAGCCGACCGTATACATGCACAATATGTCCAAAATCGTTCTTCTCGCTCCAAAGCTTATACAAGCACAATAAGTCTCACGATATCTTAAGTGCAAAGGCGGATAACTGTTCCAGGTTCAAATGTGAAAAGCTTTGTGAAAAGCTTTGTAGTTCAAGGGACCGACTGAATAGTCACATGAATATGCATCGACGCAAACGTCCTTTCAAGTGCGACACCTGTCCCAAAACGTTTATGAGCCCAGATACACTCTCGTCACACAAAAAACTGCATGCAGATGATGGGGTAGGTGAGTGCACGTTATGCAATCAAAAATTTACGGACAGTAATAAGCGGCGGAGGCACGAGAAGACGCACACAAATATCAGCAAATATCAGTGTGCAAAATGTAAAAAGTATTTTAGATTGGAAGATCAGCACCGCAGTCATTTGGAAGATAATAAATGCAAAGGATATGCTTCAGAACAGCTATTTGAATGTTCCAAGTGTGAAAATGAATCATTCGTAAGTATTGAGCTCCTAAATCAGCACAAAGTCGAAGTTCATCCACCcccgaaaaaaaatcatgcatgCTCGATTTGTGAGAAATCATTCAGGTCGAGTTCAAGGCTTAAAGTGCATATGAACGTTCATACCGGCAATCGACCGTATAAGTGCACAGTGTGTCCTAAAAAGTACGGCTGCCCCCAGAGCTTACGCCAGCACAAATTAGATCACAACTTCTTAAGCGCAGATGGGAAGATTCGTGGCAGATTCAAATGTACGCTCTGTGAAAAGTCTTACTACTCAAAAACCAATCTGAATAGTCACATGCATTTTCATCGTGGCGAACGTCCTTACAAATGCGAAATATGTCCCAAGTCGTATACGAGCGCAAAATCACTCAGATCACACATAAAAACGCATTCTGATGAGAGAAAATATGAGTGCAATTTTGATCGCCGTGTGGACGAGAAATCGCATACAAATAGCCGTATGAAATATCGAtgtgaaaaatgtaaaatgtatTTTAGATTGAAGAATCAGTACGGCAGCCATTTGAAAGACAATAAGTGCAAAGGATATGCTCTGGATAAGCCATTTCAATGTTCCAAGGGTGATAATGAATCATTCGCAACCATTGAGAATCTCATTCGACACAAAGCTAAAGATAAGTGCAATAGAAATTGCCAAGAGTCCGATCATATTCGAGAAAATAAGAAATGTGAAACACAAGTTCATAGTGAAaccaaaaacattcaaaatgatGAGCAATCACAGAAGAATGATGCGTTCGAGAAGAACAGTGGTTTATCTGTAAAGAAGGAAGTTGAAATCAACGAAATACAATTGCAAGAGCAGATTTTCGATGGAGCCGAAGTGAAGAAAAGTCTGCTTGACCACAGCGCTAATGCCGAGAAACGGAGTGCAATTGTAAATGGACTACGCAACGAAGTAACCCTGTGTTTTACGAAGGCGAAGAATCGATCTTAA
Protein Sequence
MSGLCNLPPQSNSILSIKEEIEIGERQLQEQIFHECEVKQSGADQSANFGKRSGIINSLCDDAEDAQPGLKDCEMKSGTIKEQLFEHNLSSKNSINSTQILREKNHTCSICAKKFRWRCELEAHMISHCGTRPYACTICPKRFTAARSLNRHMFTCGDNGKFRSRYKCTVCEKSFSRSEGLNSHMNIHRGERPFKCDICNKSFARKSTLYSHNRTHSRDKKFECALCNKTFIYASNHRRHEKLHSNGRLKYQCDICKHYFWSDYQYRSHLEGNKCKGNPQESNMHTVRATETRFQCSKCDHESFASIELLNRHKVQSHLPSKTHSCSVCGKAYTHKFRLEIHMNSHTGSRPYTCTICPKSFFSLQSLYKHNKSHDILSAKADNCSRFKCEKLCEKLCSSRDRLNSHMNMHRRKRPFKCDTCPKTFMSPDTLSSHKKLHADDGVGECTLCNQKFTDSNKRRRHEKTHTNISKYQCAKCKKYFRLEDQHRSHLEDNKCKGYASEQLFECSKCENESFVSIELLNQHKVEVHPPPKKNHACSICEKSFRSSSRLKVHMNVHTGNRPYKCTVCPKKYGCPQSLRQHKLDHNFLSADGKIRGRFKCTLCEKSYYSKTNLNSHMHFHRGERPYKCEICPKSYTSAKSLRSHIKTHSDERKYECNFDRRVDEKSHTNSRMKYRCEKCKMYFRLKNQYGSHLKDNKCKGYALDKPFQCSKGDNESFATIENLIRHKAKDKCNRNCQESDHIRENKKCETQVHSETKNIQNDEQSQKNDAFEKNSGLSVKKEVEINEIQLQEQIFDGAEVKKSLLDHSANAEKRSAIVNGLRNEVTLCFTKAKNRS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01044117;
90% Identity
iTF_01044117;
80% Identity
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