Nkoe004461.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nemapogon koenigi
Gene Symbol
Hr39
Assembly
GCA_963924495.1
Location
OZ004632.1:2725096-2738815[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.18 2.3e+03 -1.8 1.0 58 173 110 228 65 261 0.48
2 4 0.84 1.1e+04 -4.1 4.0 118 163 287 332 228 353 0.58
3 4 5.4e-08 0.00072 19.6 0.1 1 20 466 485 466 505 0.89
4 4 4.9e-65 6.5e-61 207.5 0.0 149 408 509 783 488 783 0.85

Sequence Information

Coding Sequence
ATGGCCAGCGAAGGTGATCCGGTCAAAGTGGAAGGTGGCCACGTGTCTGTCACCACGATCAGTATGTCGGGTCCAGAGACCAGCAGTGGTCAGTTCTCATATAGTTCGAGTGGTGTGCGGATCAGCGTGTCTTCAGAACCGCCGCCACACGATGAGGATTCCAATGACGCTGAGATATCCAAAATTGATTTCACGCAACATCAGTATGAGGTGAACATGCGTAACAAGAAGAAGAGACCCTCAAGTGGCACGCAATGTACCGAGACCCAGGCAACGGTGGATAGAGAAAGGCCTATGTCCTGGGAAGGAGAATTGTCTGACTCCGAAATGGTTATAGACACTAGTGCTAATAATGATGAAAACAGCAGTTCCCTGGACTTGCAATCATCGCGGGATTCAATAGACACTCTTAGAAATGTGACCATAAAAACGGAGCCCATGAAATCGGACCGACTGGAAGGGTTTCAGAGTTTGGATGATCAGCATGGTTTAGACCTGAAGTACAATACTACAAGTCTGTCGCAGCCATTACAACCGCATCAGAGAAGTCTTAGCATGAATAGGATTTCCGTATTAAAAGACAGTTCATCCATATTCGGTATGAGACGGCCATCATCGCCCACAAGCAGTGCCAAGTCCTCGCTCGTGCTAAATTCTGACCAGAAGAATATACCAACTATAGTTGCTCTATCAACCACACCGGAAGTTCAGAATTTGACCATAAAGAAGGAGAATATTGGCCAATGTCCACAAACCCCAATTGCTGAAGTGAAATGCGAACTGACAGCATCTTCGGGCTTCGATAAATTGTCAGGAGTTCACGGATCACCGCTACTTGGTCGACTGCCGCGGGTGCTGTCAAGCGCCAGTACTGATTCTGCCGTCCATTCCATGTATACTCATAGTGTATACAGCAGTCCGTCGGCCAGTCCTCGCGCGAACCGTCACTACACTCCATCCTTATCGCGGAACAATAGTGACGCGTCTCACTCGTCTTGCTACAGCTACAGCTCGGAGTTCTCACCTACACACTCACCGGTTCAGGGTCGCCACCCGCACGGAGTAATATTCCGCGAGGCGGCCGGTGTGTTCCCGCCCTCACCAGCTCACGATGAGGAAGTGGATCCTAACGATGATcgctatcatcatcatcagggGATTAGTAGGCAACAACTAATTAACAGtccATGTCCGATATGTGGAGACAAAATAAGCGGTTTCCACTACGGTATATTCTCGTGCGAGTCCTGCAAAGGTTTCTTCAAACGGACAGTTCAGAATAGAAAGAACTACATGTGCCTGCGCGGCGGGAACTGCCCGGTTACAGTAGCTACAAGAAAGAAGTGTCCGGCATGTCGGTTTGATAAGTGTCTCGGGTGTGGCATGAAACTTGAAGCGATTCGCGAGGATCGTACACGTGGCGGTCGCTCCACGTACCAGTGCTCCTATTCCCTGTCCGGCGCCGCGTCTACCGGGTCGTTGTTGTCTGCGCATGCGCCGGCCACATTGCGACACGCCTCAAGTCTCACCTCGGTGAATGGTCCCTTGTCATACAACAGCAGAGGAGAACTAACAAACAGATCTCCGGAGGTACCAGCATTATTACAGGAAATAATGGACGTAGAACACCTATGGCAATACAACGAATCTGAGTTGACTCGTCTCGGCAAATCGACAGGGGGTAGCCCGTCTAACAACCCTCTGCTGGCTGCCAGCGGGATCACAGCCCAAAACTCCAGTCCAGATTTTCTGGCAGACTTGTGCAATATAGCGGACCATAGACTGTACAAAATCGTCAAGTGGTGCAAGAGCTTGCCGCTGTTTAAGAATATCTCTATCGACGACCAGATTTGTCTGCTGATCAACAGTTGGTGCGAGTTGTTGGTGTTGTCATGTTGCTACCGAGGGGTGGCCACGCCCGGAGTGGTGGGGGTTGGTGCGGGAGGGGGGATGACGCTCCAGCAAAGTGCTAAGTTGGGCTTAACACCGTGTATAGAACGTATGCTCAGTTTTACTGATCACCTAAGACGACTTCGCGTAGATCGGTACGAGTATGTGGCGCTAAAAGTTATAGTCCTTCTTACTTCAGACGCGTCTGAACTTCGCGAGGCGGAGAAGGTTCGTGCCTCCCAAGAGAAAGCGTTAGCGGCGCTACAAGCTTACACCGCGTCACACTCACCGGACACTCCTGCTAAATTTGGGGAATTGTTGCTGCGTATACCTGAGTTGCAGAGAACTTGCCAGttcttCATGCAAGTGGGTAAAGAAATGCTGAACCCGGCCAACAAAAGTAAAGACAGCGACGCACCTAGCTTTAACCTGTTAATGGAACTACTCAGAGGCGACCATTGA
Protein Sequence
MASEGDPVKVEGGHVSVTTISMSGPETSSGQFSYSSSGVRISVSSEPPPHDEDSNDAEISKIDFTQHQYEVNMRNKKKRPSSGTQCTETQATVDRERPMSWEGELSDSEMVIDTSANNDENSSSLDLQSSRDSIDTLRNVTIKTEPMKSDRLEGFQSLDDQHGLDLKYNTTSLSQPLQPHQRSLSMNRISVLKDSSSIFGMRRPSSPTSSAKSSLVLNSDQKNIPTIVALSTTPEVQNLTIKKENIGQCPQTPIAEVKCELTASSGFDKLSGVHGSPLLGRLPRVLSSASTDSAVHSMYTHSVYSSPSASPRANRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHGVIFREAAGVFPPSPAHDEEVDPNDDRYHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYSLSGAASTGSLLSAHAPATLRHASSLTSVNGPLSYNSRGELTNRSPEVPALLQEIMDVEHLWQYNESELTRLGKSTGGSPSNNPLLAASGITAQNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVATPGVVGVGAGGGMTLQQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDASELREAEKVRASQEKALAALQAYTASHSPDTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDSDAPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01386822;
90% Identity
iTF_01041911;
80% Identity
iTF_01041911;