Nsal002026.1
Basic Information
- Insect
- Nebria salina
- Gene Symbol
- Hr39
- Assembly
- GCA_944039265.1
- Location
- CALUEJ010000012.1:1328379-1331436[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.8 8.9e+03 -3.4 0.2 111 140 20 47 5 80 0.54 2 4 0.53 6e+03 -2.8 5.0 46 178 202 245 108 302 0.50 3 4 5.1e-12 5.7e-08 33.5 0.4 1 141 411 532 411 554 0.56 4 4 1.2e-75 1.4e-71 243.0 1.4 149 408 475 754 469 754 0.86
Sequence Information
- Coding Sequence
- ATGGCCGCAGAGATGCGTTCTCCAAACGTATCTGTGACCGCAATCAATGTCGATCAGCATGCAGACTATTTTAACCCAAACACAATTAACATTACCAACAGCATGCATACTCACACCACCAGCACCATCGCGGCAGCTATATCCGAGTCGGGCATTCGAGAGCCAACGGACAGTGGATCGGATGCAGAGGTCGCCCAAATCGATTTCCAAAGTAGCGTCAGTATGCGCTCGAAAAAAATCGACGATCTAGCCGATATTTCACGGCCTATGTCCTGGGAAGGGGAACTCTCCGACGGCGGCGGTGACATGTGCGTTGATGAGGATAGCGTATCGAATTGTCCGGAAAATTTAACTGTTACCCATCAAAACAAACCCATAACAGTAACGAGTTCTTTACCGGAACCAAAAGACAGTCCAGTGCTAAGACTGAAACAACCTGCAGTTGGCAACTATTCCTTGCATTCGACGCCTAGCAATTCTCCCTTGATGGGGCAGCGGCACATGGGGGGCCAGCCTCATATCCTGGGGCATAAAGGGTTGAATGTACCGCCGACACCGAGTCCCGATTCTGCTATCCATTCGGCGTACAGTGTATTTAGTTCACCGAGTCAATCTCCATTAACTCAGAGACATGTTACGCTCACACCATCTTTGTCGCGAAATAATAGCGATGCGTCACATTCGAGTTGTTGCAGTTATTCCAGTGTGTCTGTATCTGTTTCACCTACACAGCAATTTTCACCCACCCATTCCCCAATACAGggTCGTCATATTCATCAAATACATGGTAGCCCATTGCAGCACAATGTCATATATAGGAACATTCAAGAAACGGTCGAGCACAGTGCCATATATGCTCGACAACAGCAAACAGCGTCCGGAACACAGATCGGCGACAGTGAACTGTTACCGGATCACGATCATGATTCAGCCACCGGATTGGATGATGAAGATAAGACTGGCATTGCACACGTACTACCTTCCGGACCTGGAATCTCACGGCAACAATTAATAAACAGcCCATGTCCTATATGCGGGGACAAAATCTCTGGATTTCACTACGGGATTTTTAGTTGTGAATCCTGCAAAGGGTTCTTCAAACGTACCGTACAGAATCGAAAGAATTACGTCTGTTTGCGAGGCGCCATTTGTCCTGTAACTGTTACAACACGCAAAAAGTGCCCAGCATGTCGATTCGATAAATGTTTACAATGTGGCATGAAACTTGAAGcaATCCGCGAAGATAGAACACGAGGTGGTCGCTCAACGTACCAATGCTCGTATACATTACCTGCTTCTTTGGTAGCCCATTCTGATGTTCGCGCAAGTAACTCAGACTTACGTCATAGTATCATAGGCGGGGAGCAACATCATACAATTGTTAAACTCGAGCCAGGAGATCAGTCCGGACAACCGTGTGCATCTTCAACAAAACGAACATGTAgctcatcatcatcatcatcatcttcTTCTAGACATAGTGTGCCAGCATTATTACAAGAAATTATGGATGTAGAACACTTATGGCATTATAGTGAAGTGGAGCTATCGAAACTCCATCAAACTAGCGCATCTACGCTAAACAAAACATCGGCAAACAACGCGTCGATTAGTTTATCATCGCATCCATTGTTGGCAGGTACAGGCCTCGCTGGGTCGGCTGATACAAACCCAGATTTTATAGCGAATCTTTGTAATATTGCCGACCATCGTTTGTATAAAATTGTCAAATGGTGCAAAAGTTTGCCACTCTTCAAGAATATATCCattgACGATCAAATATGTTTACTGATCAATTCCTGGTGCGAATTGCTACTGTTTTCGTGTTGTTATCGGTCGATGGTTAGTCCGGGCGAAATTAGAGTCTCTTTGGGAAAGAGTATCAACTTGGTTCAAGCTCGCGATATGGGCCTTCAAGCTTGCATTGAACGTATGTTGAATTTCACTGATCATTTAAGACGATTACGAGTTGATCGTTATGAATATGTTGCCATGAAAGTGATTGTACTACTTACTTCAGATACTTCAGAATTACGTGAAGCAGAGAAAGTTCGTGCTTCGCAAGAAAAAGCTCTACAAGCTTTACAGGGTTACACTCTGATGCACTATCCGGATATACCTGCCAAATTCGGCGAATTACTTTTACGAATACCCGAACTACAACGAACTTGTCAGgTGGGAAAAGAAATGCTTACGATCAAATCAAAAGATGGAGAAGGACCTAGTTTTAATCTGCTCATGGAATTACTCCGAGGGGAccactaa
- Protein Sequence
- MAAEMRSPNVSVTAINVDQHADYFNPNTINITNSMHTHTTSTIAAAISESGIREPTDSGSDAEVAQIDFQSSVSMRSKKIDDLADISRPMSWEGELSDGGGDMCVDEDSVSNCPENLTVTHQNKPITVTSSLPEPKDSPVLRLKQPAVGNYSLHSTPSNSPLMGQRHMGGQPHILGHKGLNVPPTPSPDSAIHSAYSVFSSPSQSPLTQRHVTLTPSLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHIHQIHGSPLQHNVIYRNIQETVEHSAIYARQQQTASGTQIGDSELLPDHDHDSATGLDDEDKTGIAHVLPSGPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAICPVTVTTRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYTLPASLVAHSDVRASNSDLRHSIIGGEQHHTIVKLEPGDQSGQPCASSTKRTCSSSSSSSSSSRHSVPALLQEIMDVEHLWHYSEVELSKLHQTSASTLNKTSANNASISLSSHPLLAGTGLAGSADTNPDFIANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSMVSPGEIRVSLGKSINLVQARDMGLQACIERMLNFTDHLRRLRVDRYEYVAMKVIVLLTSDTSELREAEKVRASQEKALQALQGYTLMHYPDIPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGEGPSFNLLMELLRGDH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01040206;
- 90% Identity
- iTF_01040206;
- 80% Identity
- iTF_01040983;