Ning000396.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nebria ingens
Gene Symbol
-
Assembly
GCA_018344505.1
Location
JADQWA010000117.1:341724-345957[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 8.7 7.1e+02 1.0 0.1 3 10 65 72 61 79 0.67
2 13 0.00051 0.042 14.3 0.2 1 23 348 370 348 370 0.95
3 13 2.7e-05 0.0022 18.3 1.6 1 23 378 400 378 400 0.99
4 13 0.00013 0.01 16.2 3.3 2 23 408 429 407 429 0.96
5 13 4.7e-06 0.00038 20.7 1.5 1 23 435 457 435 457 0.99
6 13 2.1e-05 0.0017 18.7 3.6 1 23 464 486 464 486 0.99
7 13 5.1e-06 0.00041 20.6 0.5 1 23 492 514 492 514 0.96
8 13 4.4e-06 0.00035 20.8 0.1 1 23 520 542 520 542 0.98
9 13 6.8e-07 5.5e-05 23.4 1.2 1 23 548 571 548 571 0.96
10 13 0.00038 0.031 14.7 1.1 1 23 577 600 577 600 0.96
11 13 2.1e-05 0.0017 18.7 2.6 1 23 606 628 606 628 0.99
12 13 0.0001 0.0084 16.5 0.4 1 23 634 656 634 656 0.94
13 13 0.0002 0.016 15.6 0.1 1 23 662 686 662 686 0.94

Sequence Information

Coding Sequence
ATGACTTCAATTGAGGTGAGGTCCAATCCTCATTGCCTCATTTGCAATAATCGCGTGAGTGTCTCCACTCGAAACTCGTATCAAATATTCAACAATAAAATTAAAACATGTTCGGAACGACCCGTCAATTTTATAATGGCGTCTGTTTTGGGCAAAGATTTGACCCAATCCAATGTCCATTCGCATATAATTTGCAAAAAATGCTTCAAACTGTTCAACGAAGTCGACGAACTCGAGATGAGGTTAGCTGAAGTCAAAGTGGACTTATTGGGGAATTATAAGCGATCGGCAATGAAGTATATAAATAACGGTACTTCATTGGAATCATTAGACGTCGATGACGTTAAAGAAGAAGATGAAACACTTGTAAAACACAGTGATAAGAAAATTCTAGATATTCCCTCAACAGATGATGAACTAGATGAGCAAAAAAAGGAAGAACTAGAAGACATCGAACGCCAACTTGCTCAATTACACAAAGAAGACGTGAAAGAAGATGAAGAGGAGGACGAAGAAAGCAAAATGGAGACGGAAGAAGAGCAGCAAAATGATCACCAAGTGATTGAAATCCATATCGCTCAAGAAGATGAAGAAGATGATGAATCACCGAATTCGTTCCAGGGTTTCGAGGTACAAACTGAAGAAACTATTGATGCCGGAGCGATGGATAATTCCGACGACTCCGATTATGAACCAACGGATGTGGATAGACAAATTGAAGCAGACGAAGCTGATAATACGTCGGCGTTATTGGAAGCAGCAGCGCTTGCAGAACAATGCGATGACGCAGATGGCGATAGCGAAGGACTGATCACAATTAAAATGGAACCTGGATCAGAAGAGATGCATAGGAATGACAGGAGACGAAGTCATCTAGCTAAGAAACAACCGAAGAAAATCATCAAAGAAGAATACCTTGAACCGGTTGTTGCTCGAGATGGCAATATGTATACATGTTTAGCGTGTGATACCGACGAGAAGTTCGCTGGTGAACCAAAAGCTATAATGAATCACGTAAAATCCGAACACGATTTACGCGTGTATATTTGTGACGTTTGCGGTCAAGATTTCCGCAAACGAAACGAACTAAGTATGCACTTAGACGAGCATGTAGCGACGGAAGAAGGTGATTTTCAGTGTGAAGTTTGCAATAGAATATTCTCGAATTTGCGTCTGTTTCGAATACATAAACGTATGCATTACCCACAATCTAAATTGTGGCATTGTGAAACTTGCGGCAAACGATATTGCTCGCGTAATCTACTAGAAGAACACATTAATACTCATACCGGTATTCGTCCTTACGTTTGCAAAACGTGTGGTAAAGATTTCGCTAGCAAATATACGTACAAAGCGCACGAGAAAACCCACGAGGTTCGCCCGCGCCCATTTCAATGTTCCCATTGTCCCAAATCGTTTCTATCCCAACAAAATCTAACGCAACATGAACGTACTCATTCAGGTGTCAAAGATTACGTTTGTCATTTATGTGGTAAGGCATTTGGTTCTCCGCATAATTTAGAAGTCCATTCGATTGTACATACTGGATATAAACCGTACATTTGCGGTGATTGCGGCAAAGCTTTCGCCCGAAAAGCTGAGATAAGGGACCATGAAAGGACCCACACCGGGGAGCGGCCATACCAGTGTGAATTTTGCGGCGCTACGTTTAGTCAAAGAAGTAATTTGCAAAGTCATAAACGGGCTACGCATTATGATGATAAACGATACAAGTGCCAGGCGTGTCAGAAAGGATTCAAACGAAGAAGATTGCTTGATTATCATATGAAAGCTGCTCATACGGGTGAACGACCGTTTAAATGCACCGTTTGTGAAGCAACATTCGTTTATCCGGAACACTTTAAAAAGCATCGGCGTATTCACACTGGTGAGAAACCGTTCTTGTGTGAAGTGTGCGGCAAAGCGTTTAACAGCAGAGATAACCGAAATGCGCATAGATTTGTGCACAGTGATAAAAAACCGTATGAGTGCCTTGTATGCGGTACTGGTTTTATGCGAAAACCACTATTATATGCGCATATGCAAACTCAAGGTCATTTAAATGACACTATAGTAGTAAACCAACCACGACTCACTACTGATGATGATCAAATTGTTACAGTTAACGCGGATGGTGAAATGGAGCTAGTTGAACATGATGTAGGCCGGTTAGAGCATATTGGTAGCGAAGCCGAAGATGGTGAAGCAAGTGAAGACACCAAACTCTACATTGCAGATCTCAAAGATCACGTGATTCTTCAAGAAAGCGACCTCTACGGTAACAGCAAAGGCATGGCCATTGTTGGGGAACCAATGGACGACAACGAAACTGTTCAAGACGCTGTAAAACATCTGATAATCGACGGTCAAGAAGTACAATTCGCAGATCAAGATGAGGAGGATGAAGACGGTGAGAGCCCTCATGTTTTAACAACTCAACATATCATCAATGAAAATGGCGAATATGAAGAAATTGTTACGGATGGACTCGTTGATGGGGACACCCAAACCATACAGACTTCGAATGGTCCGATCCAGCTAGTGCATATTCGGATACCTTCGGCTGATGGCGAAGAAGAGGAAGAGGCTTGGGTAAAAATTGTTCCGGAATAA
Protein Sequence
MTSIEVRSNPHCLICNNRVSVSTRNSYQIFNNKIKTCSERPVNFIMASVLGKDLTQSNVHSHIICKKCFKLFNEVDELEMRLAEVKVDLLGNYKRSAMKYINNGTSLESLDVDDVKEEDETLVKHSDKKILDIPSTDDELDEQKKEELEDIERQLAQLHKEDVKEDEEEDEESKMETEEEQQNDHQVIEIHIAQEDEEDDESPNSFQGFEVQTEETIDAGAMDNSDDSDYEPTDVDRQIEADEADNTSALLEAAALAEQCDDADGDSEGLITIKMEPGSEEMHRNDRRRSHLAKKQPKKIIKEEYLEPVVARDGNMYTCLACDTDEKFAGEPKAIMNHVKSEHDLRVYICDVCGQDFRKRNELSMHLDEHVATEEGDFQCEVCNRIFSNLRLFRIHKRMHYPQSKLWHCETCGKRYCSRNLLEEHINTHTGIRPYVCKTCGKDFASKYTYKAHEKTHEVRPRPFQCSHCPKSFLSQQNLTQHERTHSGVKDYVCHLCGKAFGSPHNLEVHSIVHTGYKPYICGDCGKAFARKAEIRDHERTHTGERPYQCEFCGATFSQRSNLQSHKRATHYDDKRYKCQACQKGFKRRRLLDYHMKAAHTGERPFKCTVCEATFVYPEHFKKHRRIHTGEKPFLCEVCGKAFNSRDNRNAHRFVHSDKKPYECLVCGTGFMRKPLLYAHMQTQGHLNDTIVVNQPRLTTDDDQIVTVNADGEMELVEHDVGRLEHIGSEAEDGEASEDTKLYIADLKDHVILQESDLYGNSKGMAIVGEPMDDNETVQDAVKHLIIDGQEVQFADQDEEDEDGESPHVLTTQHIINENGEYEEIVTDGLVDGDTQTIQTSNGPIQLVHIRIPSADGEEEEEAWVKIVPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01041107;
90% Identity
iTF_01039478;
80% Identity
-