Nbre021943.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nebria brevicollis
Gene Symbol
-
Assembly
GCA_944739395.1
Location
CALYJC010000747.1:83047-86923[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00086 0.08 14.3 0.2 1 23 347 369 347 369 0.95
2 12 4.5e-05 0.0042 18.4 1.6 1 23 377 399 377 399 0.99
3 12 0.00021 0.02 16.2 3.3 2 23 407 428 406 428 0.96
4 12 8e-06 0.00074 20.7 1.5 1 23 434 456 434 456 0.99
5 12 3.4e-05 0.0032 18.7 3.6 1 23 463 485 463 485 0.99
6 12 8.5e-06 0.00079 20.6 0.5 1 23 491 513 491 513 0.96
7 12 7.3e-06 0.00068 20.8 0.1 1 23 519 541 519 541 0.98
8 12 1.1e-06 0.00011 23.4 1.2 1 23 547 570 547 570 0.96
9 12 0.00064 0.059 14.7 1.1 1 23 576 599 576 599 0.96
10 12 3.5e-05 0.0033 18.7 2.6 1 23 605 627 605 627 0.99
11 12 0.00017 0.016 16.5 0.4 1 23 633 655 633 655 0.94
12 12 0.00033 0.031 15.6 0.1 1 23 661 685 661 685 0.94

Sequence Information

Coding Sequence
ATGACTTCAATTGAGGTGAGGTCTAATCCTCATTGCCTCATTTGCAATAATCGCGTGAGTGTCTCCACTCGAAATTCGTATCaaatattcaacaataaaattaaaacatgttCGGAACGACCCGTCAATTTTATAATGGCGTCGGTTTTGGGCAAAGACTTGACCCAAACCAACGTTCATTCGCATATTATATGCAAAAAATGCTTCAAATTGTTCAACGAAGTCGACGAACTCGAGATGAGgTTAGCTGAAGTTAAAGTGGACTTATTGGGGAATTATAAGCGATCAGCAATGAAGTATATAAATAACGGCACTTCATTGGAAACGTTAGAATCCGAGGAGATTAAAGAGGAAGATGAAACACTGAAGCACAGTAATAAGAAAATTTTAGATATTCCCTCAACAGATGATGAACTAGATGAGCAAAAAAAGGAAGAACTAGAAGACATCGAACGCCAACTTGCTCAATTGCACAAAGAAGACGCGAAAGAAGATGAAGAGGACGACGAAAACAAAATGGAGACGGAAGAAGACCAGCAAAATGATCACCAAGTGATTGAAATTCACATCGCTCAAGACgaagaagatgatgatgatgaatcGCCGAGTTCGTTCCAGGGTTTCGAGGTACAAACTGAGGAAACTATTGATGCTGGAGCAATGGATAATTCCGATGATTCCGATTATGAGCCAACGGATGTCGATCGACAAATTGATGCCGACGAAGCTGATAACACTTCAGCGTTATTGGAAGCAGCAGCGCTTGCAGAACAATGCGATGATGCAGATGGCGACAGTGAAGAACTGATTACTATTAAAATGGAACCTGGATCGGAAGATATGCAGAGGATTGAAAGGAGACGTAGTCACTTATCTAAAAAACCACCGAAGAAAGTCATCAAAGAAGAATATCTTGAACCGGTTGTTGCCCGAGATGGCaatatgtatacatgtttagCGTGTGATACTGACGAGAAGTTCGCTGGTGAACCAAAAGCGATAATGAATCACGTGAAAACCGAGCACGATTTACGCGTTTATATTTGCGACGTTTGCGGCCAAGATTTCCGCAAACGAAACGAATTAAGTATGCACTTAGACGAGCATGTGGCGACCGAAGAAGGTGATTTCCAGTGTGAAGTTTGCAATCGAATATTCTCCAATTTACGATTGTTTCGAATACATAAACGTATGCACTACCCACAATCGAAATTGTGGCATTGTGAAACTTGCGGCAAACGATACTGCTCGCGTAATCTATTAGAAGAACACATCAACACTCACACTGGTATTCGTCCGTACGTTTGCAAAACGTGTGGCAAAGATTTCGCTAGCAAATATACGTACAAAGCGCACGAGAAAACGCACGAGGTTCGTCCGCGACCTTTCCAATGTTCCCATTGCCCCAAATCGTTTCTATCCCAGCAAAATCTCACGCAACACGAACGTACCCATTCGGGCATCAAAGATTACGTTTGTCATTTATGCGGCAAGGCGTTTGGTTCTCCGCATAATTTAGAAGTGCATTCGATTGTACATACTGGTTATAAGCCGTATATTTGCGGTGATTGCGGTAAAGCTTTCGCGCGGAAAGCCGAGATAAGGGATCACGAAAGGACCCACACCGGGGAGCGACCTTACCAGTGTGAATTTTGCGGCGCTACCTTCAGTCAAAGAAGTAATTTGCAAAGCCATAAACGAGCTACGCATTATGATGATAAACGGTACAAGTGCCAGGCGTGTCAAAAAGGATTCAAACGAAGAAGattgcTTGATTACCATATGAAAGCTGCCCATACGGGTGAACGACCGTTTAAATGTACCGTTTGTGAAGCCACGTTCGTTTATCCGGAACACTTTAAGAAGCATCGCCGCATTCACACTGGTGAAAAACCGTTCTTATGCGAAGTGTGCGGCAAAGCGTTTAACAGCAGAGATAACCGAAATGCGCATAGATTTGTGCACAGTGATAAAAAACCGTATGAGTGCCTTGTATGCGGTACCGGTTTTATGCGAAAACCATTATTGTACGCGCATATGCAAACTCAAGGTCATTTAAATGACACCATAGTCGTAAACCAACCACGACTCACCACCGATGATGATCAAATCGTTACAGTTAACGCTGATGGTGAAATGGAACTAGTCGATCATGACGTAGGCCGACTAGAGCATATTGGTAGCGAAGCCGAAGATGGTGAAGCAAGCGAAGACACCAAACTCTACATTGCCGATTTGAAAGATCATGTGATTCTTCAAGAAAGCGACTTGTACGGCAACAGTAAAGGCATGGCTATTGTTGGGGAGCCATTGGACGACAATGATACCGTTCAAGACGCTGTCAAGCACTTGATAATCGACGGTCAAGAAGTCCAATTCGCCGATCAAGACGAGGAGGACGAAGACGGTGAAAGTTCTCATGTTTTAACAACTCAACATATCATCAATGAAAACGGCGAGTATGAAGAAATTGTCACGGATGGACTTGTTGATGGGGACACCCAGACCATACAGACTTCGAATGGCCCGATTCAGCTCGTGCATATTCGGATACCTTCGGCTGACGGTGAAGAAGAGGAAGAGGCATGGGTAAAAATTGTTCcggaataa
Protein Sequence
MTSIEVRSNPHCLICNNRVSVSTRNSYQIFNNKIKTCSERPVNFIMASVLGKDLTQTNVHSHIICKKCFKLFNEVDELEMRLAEVKVDLLGNYKRSAMKYINNGTSLETLESEEIKEEDETLKHSNKKILDIPSTDDELDEQKKEELEDIERQLAQLHKEDAKEDEEDDENKMETEEDQQNDHQVIEIHIAQDEEDDDDESPSSFQGFEVQTEETIDAGAMDNSDDSDYEPTDVDRQIDADEADNTSALLEAAALAEQCDDADGDSEELITIKMEPGSEDMQRIERRRSHLSKKPPKKVIKEEYLEPVVARDGNMYTCLACDTDEKFAGEPKAIMNHVKTEHDLRVYICDVCGQDFRKRNELSMHLDEHVATEEGDFQCEVCNRIFSNLRLFRIHKRMHYPQSKLWHCETCGKRYCSRNLLEEHINTHTGIRPYVCKTCGKDFASKYTYKAHEKTHEVRPRPFQCSHCPKSFLSQQNLTQHERTHSGIKDYVCHLCGKAFGSPHNLEVHSIVHTGYKPYICGDCGKAFARKAEIRDHERTHTGERPYQCEFCGATFSQRSNLQSHKRATHYDDKRYKCQACQKGFKRRRLLDYHMKAAHTGERPFKCTVCEATFVYPEHFKKHRRIHTGEKPFLCEVCGKAFNSRDNRNAHRFVHSDKKPYECLVCGTGFMRKPLLYAHMQTQGHLNDTIVVNQPRLTTDDDQIVTVNADGEMELVDHDVGRLEHIGSEAEDGEASEDTKLYIADLKDHVILQESDLYGNSKGMAIVGEPLDDNDTVQDAVKHLIIDGQEVQFADQDEEDEDGESSHVLTTQHIINENGEYEEIVTDGLVDGDTQTIQTSNGPIQLVHIRIPSADGEEEEEAWVKIVPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01041107;
90% Identity
iTF_01041107; iTF_01040297;
80% Identity
-