Ning010236.1
Basic Information
- Insect
- Nebria ingens
- Gene Symbol
- Hr39
- Assembly
- GCA_018344505.1
- Location
- JADQWA010000170.1:43410-48404[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.091 5.4e+02 -0.3 0.3 105 143 14 50 2 83 0.62 2 4 1.8 1.1e+04 -4.6 7.3 76 183 144 250 108 294 0.44 3 4 6e-11 3.6e-07 30.0 0.9 1 118 411 508 411 545 0.51 4 4 2.3e-75 1.4e-71 242.1 1.5 145 408 467 750 455 750 0.87
Sequence Information
- Coding Sequence
- ATGGCCGCAGAAATGCGTTCGCCAAACGTATCTGTGACCGCAATCAATGTCGACCAGCATGCAGACTATTTTAACCCAAACGCAACTAGCATCACCAACAGCATGCATACTCACACCACCAGCACCATTGCGGCAGCTATATCAGAGTCTGGAACTCGGGAGCCAACGGACAGTGGATCTGATGCAGAGGTCGCCCAAATCGATTTCCAAAGTAGTGTTAGTATGCGCTCAAAAAAAATCGACGATCTAGCCGATATTTCACGGCCTATGTCCTGGGAAGGTGAACTCTCCGACGGTGGCGGTGACATGTGCGTTGATGAGGATAGCGTATCGAATTGTCCGGAGAATTTAACTGTTACCCATCAAAACAAACCCATAACAGTCACGACTTCTCTACCGGAACCGAAAGACAGTCCAGTGCTAAGACTGAAACAACCTGCAGTTGGCAACTATTCCTTGCATTCAACGCCTAGTAATTCTCCCTTGATGGGGCAGCGACACATGGGGGCACAGCCTCATATTATGGGGCATAAAGGGTTGAATGTACCGCCAACACCGAGTCCCGATTCCGCTATTCATTCAGCGTATAGTGTATTTAGTTCACCGAGTCAATCTCCATTAACTCAAAGACATGTTACGCTAACACCATCTTTGTCGCGAAATAATAGCGATGCGTCACATTCGAGTTGTTGCAGTTATTCCAGTGTTTCTGTATCTGTTTCACCTACGCAACAATTTTCACCCACCCATTCACCAATACAGGGTCGTCATATTCATCAAATACACGGTAGCCCATTGCAGCACAATGTCATATATAGAAACATCCAAGAAACGGTCGAGCACAGTGCCATATATGTTCGACAACAGCAAACAGCGACCGGAGCACAGATCGGCGACACTGAACTATTGACGGATCACGATCATGATTCAGCCACTGGATTGGATGACGAAGATAAGACTGGCATTGCCCACGTATTACCCTCCGGACCTGGTATTTCACGGCAACAATTAATAAATAGTCCATGTCCTATATGCGGTGACAAAATCTCCGGATTTCACTACGGAATCTTTAGTTGTGAATCCTGCAAAGGGTTCTTCAAACGTACTGTACAGAACCGAAAGAATTACGTGTGTTTGCGAGGCGCCATCTGTCCTGTAACGGTTACAACACGCAAAAAATGCCCAGCATGTCGATTCGATAAATGTCTACAGTGTGGCATGAAACTTGAAGCAATCCGTGAAGACAGAACACGAGGTGGACGCTCAACGTATCAATGCTCGTATACATTACCTGCTTCTTTGGTAGCACAATCTGATGTACGCGCAAGTAACTCGGACTTACGTCATAGTATTGGCGGGGAGCAACATCATACGATTGTTAAACTTGAGCCGGGAGATCAATCCGGACTACCGTGTGCATCTTCAACAAAACGAACATGCAGTTCGTCATCTTCTTCTTCTAGACATAGTGTACCAGCATTATTACAAGAAATTATGGATGTAGAACACTTATGGCATTATAGTGAAGTGGAGCTATCAAAACTCCATCAAAGTAGTGCCTCTACACTAAACAAAACATCGGCAAACAACGCCTCAATCAGCTTATCATCGCATCCACTGTTAGCAGGTACAGGTCTCGCTGGCTCCGCTGATACAAACCCAGATTTTATTGCGAACCTGTGTAATATTGCCGATCATCGTTTGTACAAAATTGTCAAATGGTGCAAAAGTTTACCACTCTTCAAGAATATATCCATTGACGATCAAATATGTTTACTGATCAATTCCTGGTGTGAATTGTTACTGTTTTCGTGTTGTTATCGGTCTATGGTTAGTCCGGGCGAAATTAGAGTCTCTTTGGGAAAGAGTATAAACTTGGTTCAAGCCCGTGACATGGGCCTTCAAGCTTGCATTGAACGTATGTTGAATTTTACTGATCATTTAAGACGATTACGAGTTGATCGTTATGAATATGTTGCCATGAAAGTTATCGTACTACTTACTTCAGATACGTCTGAACTACGTGAAGCAGAGAAAGTTCGTGCATCGCAAGAAAAAGCTCTACAAGCTTTACAGGGTTACACTCTGATGCACTATCCAGATATACCTGCCAAATTCGGGGAATTACTTTTACGAATACCCGAACTACAACGAACTTGTCAGGTGGGAAAAGAAATGCTTACGATCAAATCAAAAGATGGAGAAGGACCTAGTTTTAATCTGCTCATGGAATTACTCCGAGGGGACCACTAA
- Protein Sequence
- MAAEMRSPNVSVTAINVDQHADYFNPNATSITNSMHTHTTSTIAAAISESGTREPTDSGSDAEVAQIDFQSSVSMRSKKIDDLADISRPMSWEGELSDGGGDMCVDEDSVSNCPENLTVTHQNKPITVTTSLPEPKDSPVLRLKQPAVGNYSLHSTPSNSPLMGQRHMGAQPHIMGHKGLNVPPTPSPDSAIHSAYSVFSSPSQSPLTQRHVTLTPSLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHIHQIHGSPLQHNVIYRNIQETVEHSAIYVRQQQTATGAQIGDTELLTDHDHDSATGLDDEDKTGIAHVLPSGPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAICPVTVTTRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYTLPASLVAQSDVRASNSDLRHSIGGEQHHTIVKLEPGDQSGLPCASSTKRTCSSSSSSSRHSVPALLQEIMDVEHLWHYSEVELSKLHQSSASTLNKTSANNASISLSSHPLLAGTGLAGSADTNPDFIANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSMVSPGEIRVSLGKSINLVQARDMGLQACIERMLNFTDHLRRLRVDRYEYVAMKVIVLLTSDTSELREAEKVRASQEKALQALQGYTLMHYPDIPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGEGPSFNLLMELLRGDH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01040206;
- 90% Identity
- iTF_01040206;
- 80% Identity
- iTF_01040206;