Basic Information

Insect: Nebria brevicollis
Gene Symbol: -
Assembly: GCA_944739395.1
Location: CALYJC010000130.1:166233-171028[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0097 0.91 11.0 3.5 1 23 464 487 464 487 0.98

2 12 0.23 21 6.7 5.2 2 23 506 527 505 527 0.97

3 12 0.00071 0.066 14.6 0.5 1 23 530 552 530 552 0.98

4 12 0.076 7.1 8.2 1.0 3 23 596 616 594 616 0.97

5 12 0.19 18 6.9 5.2 1 23 622 644 622 644 0.94

6 12 1.5e-05 0.0014 19.9 5.4 2 23 653 674 652 674 0.96

7 12 1.5e-06 0.00014 23.0 0.9 1 23 680 702 680 702 0.98

8 12 0.12 11 7.6 0.5 1 23 711 734 711 734 0.94

9 12 0.12 12 7.5 5.5 2 23 741 762 740 762 0.97

10 12 4.3e-05 0.004 18.4 1.1 1 23 768 790 768 790 0.97

11 12 1.2e-06 0.00011 23.3 1.7 2 23 796 817 795 817 0.97

12 12 0.0025 0.24 12.9 6.2 1 23 824 846 824 846 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0097	0.91	11.0	3.5	1	23	464	487	464	487	0.98
2	12	0.23	21	6.7	5.2	2	23	506	527	505	527	0.97
3	12	0.00071	0.066	14.6	0.5	1	23	530	552	530	552	0.98
4	12	0.076	7.1	8.2	1.0	3	23	596	616	594	616	0.97
5	12	0.19	18	6.9	5.2	1	23	622	644	622	644	0.94
6	12	1.5e-05	0.0014	19.9	5.4	2	23	653	674	652	674	0.96
7	12	1.5e-06	0.00014	23.0	0.9	1	23	680	702	680	702	0.98
8	12	0.12	11	7.6	0.5	1	23	711	734	711	734	0.94
9	12	0.12	12	7.5	5.5	2	23	741	762	740	762	0.97
10	12	4.3e-05	0.004	18.4	1.1	1	23	768	790	768	790	0.97
11	12	1.2e-06	0.00011	23.3	1.7	2	23	796	817	795	817	0.97
12	12	0.0025	0.24	12.9	6.2	1	23	824	846	824	846	0.96

Sequence Information

Coding Sequence: ATGCCGTACAAAGGTGATTCCACCTGGTGCGGCGCTAAGAATTGTGAAATTCGTAAAAAACGTTCGAAACTAGACGTAAAAGTTAGTTTCTTCAGATTTCCAAAAGAACCGGACAGATTAAAACACTGGATTGAAAATACAGAACGATATGATTTGATAGATAAATCACCTCAATACTGTCACTTGAATGTTAGGCTATGTGGATCACACTTTGAGGATAAAATGTTTCTCAATGATGTACAAAATAGGCTACAACCCCATGCAGTTCCTACTGTTTTCCCCGGTTCCAGAAAATTGCTATCTTTTCCTCAAAGAACTTGTTGCGTTCCAAATTGTTTTATTCCTGGTGATAGTTACGTTGGGTTTCCAGTTAAAAAACCAGAATTATTGAAAATCTGGTTAGAGAATATAAACTATCCGAGTTTATTATCACTATCTTATAGTGAATTACTAAAAAAACACGTTGTATGCTCGAGACATTTTGAATCGAAATACGTAGAAATGTGTCGAACACAATCAAAATCATACGTTGTTACCATAGATGCTATTCCAACACTACATTTAAACGACtATACTGAAGATTGTATCgaaattgatataaaatcGGATTCGATTTTAAAATCGATATTATTGGGAAGTAAACATGTTGACAAAACTTATGAAAAACATATAGTTCCTGAGtctattttaaacaatagcgaTGATCTTATTTCAAATTCTATTAAGGAAGAAGAACAAACAGattACATCGTCGACATTTTAGAGCCTTTAGCAACCTATTGTAGATTTTGCGCAAATATTTACCCAGCTACTGATCTAAAATCAGTATTCAATGATGATCTTAGTGaagaatatttagaaatattaaaccTATATATGCCTGGAATGATTAATAAGGACGATAACTTACCGCAAGAAATTTGCGAATCGTGTTTGAGCAAACTGGAGTCTTGTTTGATTACATTAAAAAGCTTTGAAAAGGCGTACGAAGAtctcaaattattatttagtacGACTTATGACACTGAAATCGACACCAAAAATACcgaaattgaattatttaatgatATTTTACCTATATTAGAATCTATTCCAGAACAAAAgtTAGTTCCAATTCTTACACCAGAAGTTATAGAAACATCTGAGCTCGAGCAAAAATTAACTGAATCAATAATCACAATTGATGACACTGAAATCGTAACACATTGTTGCTTAAAATGCGATGCGCAATTCGAAAATCACCAAGACTTTCTTGACCATTCATTTCGCATACACTTAATGACAAAAGCGGACAAAATCGTTTCTCGAATAATAAGATCGAAAAAACCAATTTCAAATACTGTACCATCCGATTCGTTAATGGATCAACTAGATTCGTAtcacattaaatatgaatgttTAATTTGTCATGTGTTGTTCGATAAAAAACATTCTCTCGTCCGTCACACCATGACGAATCATTCAACGGCGAAACGGGTTAAATATTCTGGTCGCATGATCCGTACTGATGTGATTAAATGCACACGATGCACCGAAACGTTCCAGAACTTGAATTCGTATCATCAACATACTAAGAAGCACATTCCGTTTAAATGCGATGAATGTGGAATCTGGTTTAATAGACAACAAAAATTAGCTGTACACCGAAAATCGCATGGTACGACGAGCTCAGATCAATCAATCAAATTGGAAAATACGGAAAGCAGTTCAAggaatgtatataaaaatagtgGTGAAACACAAAAGAAGTATAAAGCAAAGAAAAAGACTCAAAAATCGCTTTTGTGCAATATATGTGGCACACTGGTCAAAAACCATTACTATATGAAGTACCACCAATTGGTGCACACCAACGAGCGCCCCTTTAAATGTGATTTATGCCCTAAACGTTTTAAAATCCAGAATCATCTCGATTTTCACCATAAAATACATGAAGACACCGGCGAGCGTAATTGCATGTGCCAAATTTGCGGTAAATGTTTCCGTACGACAGCTTTACTGCGCAAACACATCCAAAGACATTCCGATAACAAACAATATGTATGTGAAGTATGTGGCTACGCGTTTAGAACGTCATTTTTACTAGAACGACATCGGAAGAAACACAATTTTATAGCTGAAATCAGAAACCATATGTGTAGAATTTGCGATGTGATAGTGGATAGTTTTAATGGTCTCAACAGGCATATGAGTGAAAAACATGATGGCGCCAAAGCACTTGAGTGTGATATTTGCCACAAGTTATTCAGTAAGCAATTGCTTCTAAAGTGCCACAGACGCACGCATACCGGTGAACGTCCGTTTCAGTGTCAGCAATGCTATAAAGCATTTACAACAAATGCGCTGTTGAAACAACATAAGGCCGTGCATGAAAAACAGGCAATGCAATGTGATATTTGCGATAAAAAATTCCGAAGATTATGGAACTTAAAGGCACATAGGAAAAAACATACGACCACGAAAACGCAACACGTGTGTTTGATTtgcaaaaaaatgtttaattctcACGCAAATTTGAACAAACACTTTCACGTACACCAAATAAAGAGTAAAAAGGTGATTGTTACATCTGAAGAAGAAAATgataatattgaatatttggaTGCACATTTGGACGAAATCGAAGAACCAAATGGTTTGACGACTTTTTCTGAAACAGTTATAGATTCGTCAGGGTTTGAAAATCCTGATTACAAGTCACCACACGatcaaattttaactacaaaaactattattattcaagctaaaaatatgaaacaaatcaaatttaaacttGTGCAATAG
Protein Sequence: MPYKGDSTWCGAKNCEIRKKRSKLDVKVSFFRFPKEPDRLKHWIENTERYDLIDKSPQYCHLNVRLCGSHFEDKMFLNDVQNRLQPHAVPTVFPGSRKLLSFPQRTCCVPNCFIPGDSYVGFPVKKPELLKIWLENINYPSLLSLSYSELLKKHVVCSRHFESKYVEMCRTQSKSYVVTIDAIPTLHLNDYTEDCIEIDIKSDSILKSILLGSKHVDKTYEKHIVPESILNNSDDLISNSIKEEEQTDYIVDILEPLATYCRFCANIYPATDLKSVFNDDLSEEYLEILNLYMPGMINKDDNLPQEICESCLSKLESCLITLKSFEKAYEDLKLLFSTTYDTEIDTKNTEIELFNDILPILESIPEQKLVPILTPEVIETSELEQKLTESIITIDDTEIVTHCCLKCDAQFENHQDFLDHSFRIHLMTKADKIVSRIIRSKKPISNTVPSDSLMDQLDSYHIKYECLICHVLFDKKHSLVRHTMTNHSTAKRVKYSGRMIRTDVIKCTRCTETFQNLNSYHQHTKKHIPFKCDECGIWFNRQQKLAVHRKSHGTTSSDQSIKLENTESSSRNVYKNSGETQKKYKAKKKTQKSLLCNICGTLVKNHYYMKYHQLVHTNERPFKCDLCPKRFKIQNHLDFHHKIHEDTGERNCMCQICGKCFRTTALLRKHIQRHSDNKQYVCEVCGYAFRTSFLLERHRKKHNFIAEIRNHMCRICDVIVDSFNGLNRHMSEKHDGAKALECDICHKLFSKQLLLKCHRRTHTGERPFQCQQCYKAFTTNALLKQHKAVHEKQAMQCDICDKKFRRLWNLKAHRKKHTTTKTQHVCLICKKMFNSHANLNKHFHVHQIKSKKVIVTSEEENDNIEYLDAHLDEIEEPNGLTTFSETVIDSSGFENPDYKSPHDQILTTKTIIIQAKNMKQIKFKLVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01039278; iTF_01040916; iTF_01041251;
90% Identity: iTF_01039278; iTF_01040916; iTF_01041251;
80% Identity: iTF_01039278;