Basic Information

Insect: Nebria brevicollis
Gene Symbol: -
Assembly: GCA_944739395.1
Location: CALYJC010000008.1:809899-812509[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.7e-05 0.0016 19.7 0.9 1 23 89 111 89 111 0.99

2 14 0.007 0.65 11.5 6.0 1 23 150 172 150 172 0.95

3 14 0.0014 0.13 13.6 0.4 3 23 177 198 176 198 0.96

4 14 0.00095 0.088 14.2 5.9 1 23 208 230 208 230 0.98

5 14 0.46 43 5.7 0.2 2 21 236 255 235 257 0.79

6 14 0.0021 0.19 13.1 1.9 2 23 264 285 263 285 0.97

7 14 0.12 11 7.6 0.6 1 23 288 311 288 311 0.94

8 14 9.4e-06 0.00087 20.5 2.0 2 23 321 342 320 342 0.97

9 14 0.0076 0.71 11.4 4.7 2 19 349 366 348 372 0.93

10 14 0.0002 0.019 16.3 0.2 2 23 383 405 382 405 0.96

11 14 4.1e-05 0.0038 18.5 3.4 1 23 412 434 412 434 0.97

12 14 0.00048 0.045 15.1 0.2 3 23 443 464 441 464 0.94

13 14 2.1e-07 2e-05 25.7 1.4 1 23 470 492 470 492 0.97

14 14 0.00019 0.017 16.4 3.1 1 23 498 521 498 521 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.7e-05	0.0016	19.7	0.9	1	23	89	111	89	111	0.99
2	14	0.007	0.65	11.5	6.0	1	23	150	172	150	172	0.95
3	14	0.0014	0.13	13.6	0.4	3	23	177	198	176	198	0.96
4	14	0.00095	0.088	14.2	5.9	1	23	208	230	208	230	0.98
5	14	0.46	43	5.7	0.2	2	21	236	255	235	257	0.79
6	14	0.0021	0.19	13.1	1.9	2	23	264	285	263	285	0.97
7	14	0.12	11	7.6	0.6	1	23	288	311	288	311	0.94
8	14	9.4e-06	0.00087	20.5	2.0	2	23	321	342	320	342	0.97
9	14	0.0076	0.71	11.4	4.7	2	19	349	366	348	372	0.93
10	14	0.0002	0.019	16.3	0.2	2	23	383	405	382	405	0.96
11	14	4.1e-05	0.0038	18.5	3.4	1	23	412	434	412	434	0.97
12	14	0.00048	0.045	15.1	0.2	3	23	443	464	441	464	0.94
13	14	2.1e-07	2e-05	25.7	1.4	1	23	470	492	470	492	0.97
14	14	0.00019	0.017	16.4	3.1	1	23	498	521	498	521	0.95

Sequence Information

Coding Sequence: ATGACATCAGAAGATAAGAAACCATTATCAACAGTCAAAGATCAAGTAGCGCAAATGTTTAATTCGATCCACAAGTTAGAAACGAAAGATAAAACGGAGGCTTTTTCGTTTGTAAGAACATATCTTGATGATAGTATAGTAGCGAAAAATGGAGTTTCTAGAAGATgccgaaaaaataatattgaaactaATACAGAAaatGCTAAAAGTAATAATCGAAAATTGATGTTTAAAACTCGGATTCAACGAGTAAAAAAAGCGTTTTATAAGTGTCGATCTTGCGGCGCACAGTTTAATACGAAATCTTTATTAATCAAGCATTTAGAAACTCATATAGGTACGCCAATATCTTGCAGATCGTGCCGAACTAGTTTTAATAGTAACATTTCATATCTATGTCACATTTCGTTGAAAATGTGTAAGAAAACTAAAAAAAGCTGGAAAACTTACTGTTGCGATCAATGCAATAAGatttttagatataAACGACATTTTGACCGACATGTGGAAGGACACAAAAGGAATAATTGTACTTACTGTGATGCACGATTAACGCGGCGAAAACAATTGGTCAATCATTTAATGATTGCGCATTCAATTAAATTGGAACGGACTGTTATGTTTAAATGTGAATATTGTGAAAAAAGatatgTAAAAAAGCGTTCTTTATATCACCATTTAAAGCAACATGCCGATGATAAAATAGTGTGTAACGAATGCGGTAAAATGAGCGCAACTCTCGACGAACACAACATTCATTTCGCTCAACACGACAAAGATAGACCGTGGAAATGCGATAAATGCAATGATCGATTCTCAAGACGacaacaatatttaatacatattaaaagACATGATCGATACAAATGCATATCGTGCGATGAAACATTCGCGTCTAAGGCTCGCGTGCTCCGACACAAACAACGAGGACATTTAGTGCACGGTTTAGAACCCCAATTAAAGTGTCCACACTGTCCCAGAGCATTCCAACGGCGGCTAACATTACAAATCCACATGAGAAAACATTCAGATGACAAACTCATGTATTGTAAATACTGTAATAAACACTTCCGCACACCTTACTTATATTTCAAACATTGCGCGACAACCGTCCACGATGTAAACTCGCCCGTAAAACAACAATTAGTTTGTGAAATATGCGGTAAACTATTCGTTAAAAAATACTTACTCGACCAGCACTTACAACGCGTTCACAATCTgtcaaaacaaacatttaagtgCGAGTATTGCGGCCACAGGACAACGAATCGCACCAACTTAGAGCGGCACCTAACTCTCCATATGGAAGATAAAAAACAGACAATCTGCGATAAGTGCGGAAAAGCGTTCTACAATATGATCACACTTAAAGATCATATATCGTACGTTCATTTGCAAGAGCGTGATTTTAAGTGTGACGAATGCGACAAAGCATTCAAACGTAATTCGGAGTTGATTCGACACAAAACGAGCCATTCGACATTACGTCCACATGTGTGTGCAACATGTGGTGTATCATATAAACGTAGTACTCATTTACGCCGCCATGAAGAAACCCAACATGGGACACAAGCGAAAAACCGACGCGTCCAACGATTGACCAAAGATGAGAACGGACAATTGATACCTGTGCCCCAACCGAAAAAATCGAAAAGTAAAAAAGCTGTAGAAACTCCAACTAACTCAAAACAAGTTATATCGTTTCTTGATCCCCAATCCAAGGAAATGGTATCGTTTACGCTGCTTAATGACATTCAAGATGGTGGTGCGTTGACTACGATAGTAAGCCTTAATAATCAAGATGTTCAAGCTTTGCCGTATCAACAAACTAACctagtttttaattcaaatgacAGTGTTATTCTTGCGAATGATTATAGTGCGCAATCGCTGAATTTAGTTGGTACTTTTGATCAAAATTTCACTGGTTTCACTTCACATGAACCGCTTCCGGCTGGTGCTAGTGTTTCTAAACCGTTTGTACCCGAAACTATACGTATTGAAAATTCGACTACTTGCGATATTTTGTTACCGGAAACTCGAATTTTAAATCTGCAATCGCAATAA
Protein Sequence: MTSEDKKPLSTVKDQVAQMFNSIHKLETKDKTEAFSFVRTYLDDSIVAKNGVSRRCRKNNIETNTENAKSNNRKLMFKTRIQRVKKAFYKCRSCGAQFNTKSLLIKHLETHIGTPISCRSCRTSFNSNISYLCHISLKMCKKTKKSWKTYCCDQCNKIFRYKRHFDRHVEGHKRNNCTYCDARLTRRKQLVNHLMIAHSIKLERTVMFKCEYCEKRYVKKRSLYHHLKQHADDKIVCNECGKMSATLDEHNIHFAQHDKDRPWKCDKCNDRFSRRQQYLIHIKRHDRYKCISCDETFASKARVLRHKQRGHLVHGLEPQLKCPHCPRAFQRRLTLQIHMRKHSDDKLMYCKYCNKHFRTPYLYFKHCATTVHDVNSPVKQQLVCEICGKLFVKKYLLDQHLQRVHNLSKQTFKCEYCGHRTTNRTNLERHLTLHMEDKKQTICDKCGKAFYNMITLKDHISYVHLQERDFKCDECDKAFKRNSELIRHKTSHSTLRPHVCATCGVSYKRSTHLRRHEETQHGTQAKNRRVQRLTKDENGQLIPVPQPKKSKSKKAVETPTNSKQVISFLDPQSKEMVSFTLLNDIQDGGALTTIVSLNNQDVQALPYQQTNLVFNSNDSVILANDYSAQSLNLVGTFDQNFTGFTSHEPLPAGASVSKPFVPETIRIENSTTCDILLPETRILNLQSQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01041139;
90% Identity: iTF_01041139;
80% Identity: -