Nbre011020.1
Basic Information
- Insect
- Nebria brevicollis
- Gene Symbol
- -
- Assembly
- GCA_944739395.1
- Location
- CALYJC010000183.1:561788-564535[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 2.6e-05 0.0024 19.1 5.7 1 23 311 333 311 333 0.98 2 15 0.0014 0.13 13.6 1.0 2 23 339 361 338 361 0.96 3 15 2.4e-05 0.0022 19.2 0.7 3 23 396 416 394 416 0.97 4 15 0.00019 0.018 16.4 2.2 1 23 420 442 420 442 0.99 5 15 1.2e-08 1.1e-06 29.6 3.4 1 23 448 470 448 470 0.99 6 15 0.8 74 5.0 1.3 1 23 558 582 558 582 0.89 7 15 0.00057 0.053 14.9 0.8 1 23 594 616 594 616 0.98 8 15 0.1 9.4 7.8 7.1 1 23 633 655 633 655 0.97 9 15 3.8e-06 0.00036 21.7 1.0 1 23 702 724 702 724 0.96 10 15 0.15 14 7.2 0.1 1 23 731 753 731 753 0.98 11 15 6.9e-07 6.4e-05 24.1 0.2 2 23 762 783 761 783 0.96 12 15 0.0088 0.82 11.2 1.3 2 21 788 807 787 808 0.93 13 15 0.025 2.3 9.7 0.5 2 23 814 836 813 836 0.94 14 15 0.0064 0.59 11.6 0.5 1 23 842 864 842 864 0.96 15 15 3.3e-05 0.0031 18.8 0.4 1 23 872 894 872 894 0.97
Sequence Information
- Coding Sequence
- ATGTTTTGTTTCGCGAAAATCTGTCGCATTTGTCTAAATGCGTCAGACTCCAAGCTGATCAAGTTAAATAATCTCGATTACGACAAGATACGAATACGGGAAAAGCTAAAATTTTGCATACCAGAAGCTATGAACGAAAAGCACTTGCCAGAATTGATTTGTATCGGTTGTTGTAAAAATTTGCGCCGGTCGTATTCGTTCAAACAAATGTGTTTACAAAACAAGGATAAATTGAACAAATACGCTTCAACACTACTCGTTTCCAAGCGACACAAACATGGTAACCTAAGCATCGGTTTGGTTGATTTTATCGAGAAAAATCAAGTCGCATTGAAAACGTCAGATGATATGCCCATTCCGAAAAATCTAAACGAAAGCGTTTCAATGCACACCATCTCGCTGAACCAATGGGATCTATTCGAAACAAAATTCACCTGCCGTTGCATTAAAGAGTACAGTTCGTTCACGGAAGAGACCCGCCATTTATGTAAAAGTTGTGAAGGTGACTTATTAGGTTTCCAACTATCGAAAGTGAAGGTAGGTATGGCCGAGAATCGTTTTAATTCATGCCAAAGTTCAAGTGAGCGCGTTGGGAATTCGCAACAAAGTGAGGTCAGTTGCGAGTACAGTTGTTCCGAATCGATGCGTTCAAGTTTGGAATCTCCGTCTTTGCGTAACAAAAATCCTCTTAACTCGCCAAATACCCGCCAAATAGATACAAATGCTACGTTAGCTGACGAATCGTCAAATCAGAACGATGCTAACTATGATTACAGCGATGTTCTAATGTGCAAGATGAAAGTAAGCAATGCACAGAACGAAGTAAATATGTTGCGCAGTGTTAGCTATAGGCAGTACAATGATCGTAGAAGTGAGCCAAGCGATGCTGAAAACAATTCGGCTAACCAAACATTCGATTTAGAGAAGAAACACAAATGTCCGCTGTGCGAAAAAAAATACACTAGGCAATACGACCTATTTCGCCATTATAAAAAACACAAAGTACCATTTATACGCTGTGTTCAATGTACAAAACAATACATGCGCCAAGAGGACTTGGACAAACATATTCGCAAATCACACAAAGGAAAACAACGTAAGTCTATAGTGCGCAAAGAAATCACACGTATTTTCGTTAAAGAACAACACGATATCGAACCAAacaatattgaaacaaatgtcAATTGTACGGTTTGCAATGAAACTTTCGAAAATCAAACACATTTAGCAGTGCACTTAATGACCCATAAAAAAGAGTTCAAATGCAAGAAATGCGATAAAGAATTCTTgcaaaaagaaaaactaaCCGAGCACTTATTAACGCATTCATTGCCGCGTATTTATCAATGCAGTTACTGTAGTAAAAGCTTCAACTATTCCAGTAATTTGAAACGTCACATGCGCGTTCACACCCCTTCAAATAAACGCGATACAAAAAACAACAAAGACAAACGAAACAACggtacaaaaaaaacaaaatctcATGATGAAAATATCGACCAAAATCATACACAAGAAATTGTGTTGTATGACCCTAAGATTGCATCGAATCAAAAGCGTGGGAAAACTAGTTCAAAATCGCTAGAAATCGCGTTATACACTCCTTTAAAATCACCCACACCCATAATAGATAACGTGTTTAACTATGCGACGGCTGTACAAATTGGTGACTACGCATGCGTAGAAAAAGATTGCAAACAATCTTTTGCGATTTTAAAGCAATATTACCGCCATTTGCACGATCATAATACGTTACGGTCGAAAGCAGATAGAAAACCTTACAGATGCGTCGAATGCGGTAAACTCTGTGTACAAATATCTACTCTATATAATCACATGTTAGTGCATCCATCcgggaaaaataaaataaatcatttggAACCGAAAGGTATGCGTTTCACATGTAAGTATTGCCGAAAAGGATACAATTACATTAAGCACTTTAATCATCATGTCGCGAAACACAAATCGATTAAAGCAGAAGCTTTGGAAGACAGTGAACTAGAACCGAACGATATGGATGACGTTAAAACGGAATTAATGGATGAAAACGACAATGATGAGATTCAAAATGCTACCGCGCAAACCTACGATTCGAAAGAATTCGCGTGCGTGCAATGCGATAAAAGTTACACGACTAAACAAAGCTTGAAACGGCATATGCTAGCACATCCAAAACAAACGGAAAAATACTCGTGTTCGATTTGCTTTGAACAATTTCTGCAACTGGGCGTGCTtgaagaacatattttaactcACTCAAAACGGTCGACTGAAGAATGGATTTGTGAAGTTTGCAATAAGGCGTTTATGCAAAAAGCGAATTTAAAGCGTCATATGATGGTACATGAAAGGCCGCTAATATGTCACCATTGTCGCGGTCGTTTCGATAATAAAAACGATCTGGTGAAGCACATCATGAAATATGCGCGTGCGCAATATTGTAAGTTGTGCAAACTGGAATTCAGCATTCGCACCGATATGGAGAAACATATGCTAGAAGATCATACGAACTCGAAAGATTATTACTGCAAtgtgtgctttgttaatttcgaaaacGCTGAATATTTTCGAAAACATGTTGTAATCCATCCACAGAAATTGGAAAGGAAATATGAATGCGCTTATTGCGAGAAAACATATCCTACGAAATCTGGATTGATTCGTCATAATCTTTCACATAAATCCTAA
- Protein Sequence
- MFCFAKICRICLNASDSKLIKLNNLDYDKIRIREKLKFCIPEAMNEKHLPELICIGCCKNLRRSYSFKQMCLQNKDKLNKYASTLLVSKRHKHGNLSIGLVDFIEKNQVALKTSDDMPIPKNLNESVSMHTISLNQWDLFETKFTCRCIKEYSSFTEETRHLCKSCEGDLLGFQLSKVKVGMAENRFNSCQSSSERVGNSQQSEVSCEYSCSESMRSSLESPSLRNKNPLNSPNTRQIDTNATLADESSNQNDANYDYSDVLMCKMKVSNAQNEVNMLRSVSYRQYNDRRSEPSDAENNSANQTFDLEKKHKCPLCEKKYTRQYDLFRHYKKHKVPFIRCVQCTKQYMRQEDLDKHIRKSHKGKQRKSIVRKEITRIFVKEQHDIEPNNIETNVNCTVCNETFENQTHLAVHLMTHKKEFKCKKCDKEFLQKEKLTEHLLTHSLPRIYQCSYCSKSFNYSSNLKRHMRVHTPSNKRDTKNNKDKRNNGTKKTKSHDENIDQNHTQEIVLYDPKIASNQKRGKTSSKSLEIALYTPLKSPTPIIDNVFNYATAVQIGDYACVEKDCKQSFAILKQYYRHLHDHNTLRSKADRKPYRCVECGKLCVQISTLYNHMLVHPSGKNKINHLEPKGMRFTCKYCRKGYNYIKHFNHHVAKHKSIKAEALEDSELEPNDMDDVKTELMDENDNDEIQNATAQTYDSKEFACVQCDKSYTTKQSLKRHMLAHPKQTEKYSCSICFEQFLQLGVLEEHILTHSKRSTEEWICEVCNKAFMQKANLKRHMMVHERPLICHHCRGRFDNKNDLVKHIMKYARAQYCKLCKLEFSIRTDMEKHMLEDHTNSKDYYCNVCFVNFENAEYFRKHVVIHPQKLERKYECAYCEKTYPTKSGLIRHNLSHKS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01041114;
- 90% Identity
- -
- 80% Identity
- -