Basic Information

Insect: Nebria brevicollis
Gene Symbol: -
Assembly: GCA_944739395.1
Location: CALYJC010000299.1:932571-934783[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0031 0.29 12.6 0.1 1 23 138 160 138 160 0.96

2 14 7.1e-05 0.0066 17.7 0.5 1 23 165 187 165 187 0.97

3 14 0.0017 0.16 13.4 7.6 1 23 208 231 208 231 0.97

4 14 0.0029 0.27 12.6 1.6 2 23 249 271 248 271 0.97

5 14 0.00085 0.079 14.3 3.0 1 23 314 336 314 336 0.99

6 14 0.024 2.2 9.8 1.5 1 20 349 368 349 371 0.95

7 14 1.5e-06 0.00014 23.0 0.7 1 23 392 416 392 416 0.99

8 14 7.5e-06 0.00069 20.8 2.4 1 23 451 473 451 473 0.98

9 14 5e-05 0.0046 18.2 1.2 1 23 479 501 479 501 0.98

10 14 0.00017 0.015 16.6 0.4 1 23 507 529 507 529 0.98

11 14 2e-05 0.0018 19.5 1.3 1 23 535 557 535 557 0.98

12 14 0.0019 0.18 13.2 0.9 1 23 563 585 563 585 0.98

13 14 1.5e-07 1.4e-05 26.2 1.7 1 23 591 613 591 613 0.97

14 14 3.3e-06 0.00031 21.9 1.1 1 23 619 641 619 641 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0031	0.29	12.6	0.1	1	23	138	160	138	160	0.96
2	14	7.1e-05	0.0066	17.7	0.5	1	23	165	187	165	187	0.97
3	14	0.0017	0.16	13.4	7.6	1	23	208	231	208	231	0.97
4	14	0.0029	0.27	12.6	1.6	2	23	249	271	248	271	0.97
5	14	0.00085	0.079	14.3	3.0	1	23	314	336	314	336	0.99
6	14	0.024	2.2	9.8	1.5	1	20	349	368	349	371	0.95
7	14	1.5e-06	0.00014	23.0	0.7	1	23	392	416	392	416	0.99
8	14	7.5e-06	0.00069	20.8	2.4	1	23	451	473	451	473	0.98
9	14	5e-05	0.0046	18.2	1.2	1	23	479	501	479	501	0.98
10	14	0.00017	0.015	16.6	0.4	1	23	507	529	507	529	0.98
11	14	2e-05	0.0018	19.5	1.3	1	23	535	557	535	557	0.98
12	14	0.0019	0.18	13.2	0.9	1	23	563	585	563	585	0.98
13	14	1.5e-07	1.4e-05	26.2	1.7	1	23	591	613	591	613	0.97
14	14	3.3e-06	0.00031	21.9	1.1	1	23	619	641	619	641	0.98

Sequence Information

Coding Sequence: atgagTGAAGAACAGTGCCGAACGTGTTTGATTAAACCGGTGGATATGATATCGTTAACGGCCGATCACGTTGTATGTGATAAGGTTATGTCCGTGTTGGATTTGATTAAAATGTGTGCGTCCGTTGAGATCGAATTGGAAGATGGCTTTCCGCAGTTCGTGTGTGTTGACTGTATACATTTAGCGGAGAAGTCATTCGAGTTCCGACTCCAGTGCAAAGAAGCAGATGACACATTACGCGCTGGTCCGGTTGTCCAATTCGACGTACTACAATTCGAAGCGGATGAAAGCGAAGAAGTTGAGGTGATTTGCGAGGAAATCGAACCGGAATGTGTTAAATTCGAATCGATACCAGACGATGAATATGACGAACAAGTTATTAAATGCGAAGAAATCGAAGTGGAAGAAACGTACCCGTGTGGCATTTGCAATTTGATATTTCCGACGGAGAACGCGTTAGCAAAACACAGCCACATACACCCACCCAACTTCTATCAATGTCCACATTGTCCCGTTAGATTTATATCCGAAACCCTACTTGAGAAACACGTCGTGAAACACTTACAAAAAACACCCGAACCTCAATTCAAACCAAACACAAAACGCCGGTTAACCATATGCTTCATGTGCTCCGATTGCGGTAAAAAATGTAACTCTTTAGCCCACTTACACTCCCACACCCGCAAATACCACCCAGTCGTTCATAAACCCAACGAAACAGAACCTAACCCTACTTCCCTCGTCAAATGTCACATATGTGACAGTTTATTCCACAGCAACGTTGATTTAGAAAGCCATATGCAATCTGTACATATTTTAACTAACAAACCCTCGAATTACCACTGTAAACTATGTTGCAAAACACTCCCAAACGTATTAGCTTGGCGGTTACATATGCAATCGCATAAAAAGCAGAAAACAACCTCAAATAACATTGCatataaatgcaaaatatGCAATTGTGATTTTAATACACTAACCGATATAAAAGAGCACTTAAACACCCATGCAATCGATGGTAAATCACTATTCCAACACTTATTATACAAGTGCACGGAGTGCACGAATAGTTTCGATTCAATTTACGAGTTTTTCCGTCACACACCTGAGCATTCAGAGTCAAAAATCGAGAATACACAAACCGGCGCGACTAGAATTGTTAAAAAACGACCGTATAAGTGTTCGTACGCGAATTGCGATAAAACGTTTCCGAGTCCAAGCGCGCTCAAAAACCATTCGCGCACCCATCAATCAGCGTGGCCGAAAAAGTGTCGCTACTGCGAtgacattttacacaaatgGCATGATTATATGGCGCACTTAAACGCGAAACACGAGCACGAGAAAACGTTTATTTGCTCGCAATGCGGTAAGAAGTTCTTCAAAGAACGTAACCTAACATCGCACATTAAAACGCACACGGGTGAACGTAATTATATGTGTGATTATTGCGGGTTTAGTTTTCACGCGCAAAATAACCTAGTCGCGCATCGGCGTATACACACCGGTGTGAAACCGTATAAGTGTACTTTGTGCCCGATGGCGTTTCCACAACACGCTGGTTTGCGTTCGCATTTATTAAACCACAGCGGGGAGAAGAAATTCGAGTGTCCTACGTGTCATAAGAAATTCTTGCGTCCTGGTGCGTTGAACACGCATATTAAAACGCATACGGGTGTTAAGGATTACGCGTGTCATTTGTGTGGGGCGCGATTTGGGGCGTCGTCGACGCGAAAGAAGCATATTTTAACGCATACAGGGGAACGGAATCATGTGTGCGATTTTTGTGGTAAGGCGTTCAGTCGCAATTCGAATTTGAATGTGCATCGAAAGATTCATACGGGTGAGACGCCGCATGTGTGCGAGATATGTGGTAAGGGTTTTATACAGGCGCATGTGTTGCGTTCGCATATGAACACGCATCGGAAGTCGCGCGATGCGTTGAAACGGGAGGCGAAGATTGCGAAACGGGATGTCGACGAGGAGGAATCGGAAGAGTTGACTGTTTTGGTTGATTTGGgcgattaa
Protein Sequence: MSEEQCRTCLIKPVDMISLTADHVVCDKVMSVLDLIKMCASVEIELEDGFPQFVCVDCIHLAEKSFEFRLQCKEADDTLRAGPVVQFDVLQFEADESEEVEVICEEIEPECVKFESIPDDEYDEQVIKCEEIEVEETYPCGICNLIFPTENALAKHSHIHPPNFYQCPHCPVRFISETLLEKHVVKHLQKTPEPQFKPNTKRRLTICFMCSDCGKKCNSLAHLHSHTRKYHPVVHKPNETEPNPTSLVKCHICDSLFHSNVDLESHMQSVHILTNKPSNYHCKLCCKTLPNVLAWRLHMQSHKKQKTTSNNIAYKCKICNCDFNTLTDIKEHLNTHAIDGKSLFQHLLYKCTECTNSFDSIYEFFRHTPEHSESKIENTQTGATRIVKKRPYKCSYANCDKTFPSPSALKNHSRTHQSAWPKKCRYCDDILHKWHDYMAHLNAKHEHEKTFICSQCGKKFFKERNLTSHIKTHTGERNYMCDYCGFSFHAQNNLVAHRRIHTGVKPYKCTLCPMAFPQHAGLRSHLLNHSGEKKFECPTCHKKFLRPGALNTHIKTHTGVKDYACHLCGARFGASSTRKKHILTHTGERNHVCDFCGKAFSRNSNLNVHRKIHTGETPHVCEICGKGFIQAHVLRSHMNTHRKSRDALKREAKIAKRDVDEEESEELTVLVDLGD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01041108; iTF_01040298;
90% Identity: iTF_01041108;
80% Identity: -