Nbre012076.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nebria brevicollis
Gene Symbol
-
Assembly
GCA_944739395.1
Location
CALYJC010000216.1:410853-413348[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.009 0.84 11.1 1.2 1 20 184 203 184 205 0.94
2 22 0.00013 0.012 16.9 2.7 1 23 211 233 211 233 0.99
3 22 3.8e-05 0.0036 18.6 0.2 1 23 239 261 239 261 0.96
4 22 5.3e-05 0.005 18.1 0.4 1 23 267 289 267 289 0.98
5 22 6.2e-06 0.00058 21.1 0.5 1 23 295 317 295 317 0.97
6 22 6.3e-08 5.9e-06 27.3 1.9 2 23 321 342 320 342 0.97
7 22 5.3e-06 0.00049 21.3 0.3 1 23 347 369 347 369 0.97
8 22 3.8e-06 0.00036 21.7 2.5 1 23 374 396 374 396 0.98
9 22 3.2e-08 3e-06 28.3 0.8 1 23 402 424 402 424 0.98
10 22 4.3e-07 4e-05 24.7 2.4 1 23 426 448 426 448 0.98
11 22 2.5e-06 0.00023 22.3 0.5 1 23 454 476 454 476 0.99
12 22 1e-06 9.3e-05 23.6 0.5 1 23 482 504 482 504 0.99
13 22 7.6e-08 7e-06 27.1 1.0 1 23 510 532 510 532 0.99
14 22 6.2e-06 0.00058 21.1 0.7 1 23 538 560 538 560 0.98
15 22 4.1e-07 3.9e-05 24.8 1.1 1 23 565 587 565 587 0.96
16 22 2.1e-06 0.0002 22.5 1.6 2 23 592 613 591 613 0.97
17 22 8.9e-05 0.0083 17.4 2.1 1 23 619 641 619 641 0.98
18 22 0.0022 0.21 13.0 7.0 1 23 647 669 647 669 0.96
19 22 1.8e-06 0.00017 22.7 0.6 1 23 675 697 675 697 0.98
20 22 0.00012 0.011 17.1 5.0 1 23 703 725 703 725 0.99
21 22 5.2e-05 0.0049 18.2 0.9 1 23 731 753 731 753 0.97
22 22 3e-06 0.00027 22.1 1.0 1 23 759 781 759 781 0.97

Sequence Information

Coding Sequence
atgtcaaattcaCACGATTTTGATATAGATAAAGTGTGCCGCACATGTTTATcaacattaaatttaaaatcgcTATTCGACGCATACTCCACACAAGATTGTTTCGACGAAATGCTCATGATATGCACATCAGTTGAGTGCTATGAAAACGATGGCTTACCGATCCAAATATGCTCGGATTGCATCAACGAGCTGAATCGCTCGTACGAATTCGCGGTAAAGTGTCGCGAAAGCGACACCAAATTACGGTTATGTATACAAAACCCATCACAGTGCACCAACGCACTTAATCCAACTTATAAAAACAACTCAATAGACACTTTAGAAACAGTTATATCACAAAATCATCTTGATAGTGAGTTAACAGTGAACAAATACGATTTAGACAGTTTAGACAACTCAACCACTGATTCATTCGAAATCGTACAAGAGGTCAGCACTGTACGGCAATTAAAAGATTGCATTAATTTGGAAACAAACAGTGATCACTCACAAGAAGCTTCCACCCCCCAACTCAACGGTGTGATAGACACCAAACGACCAACTACATTTACTTGCTCACATTGTGGCAGTTTATTtccaaacaaaacaaatttagacGCTCACACACTGCATTCTTGTGATAAACAATACACCTGCACGATATGTAACAACTCATTCGAATTACAACACCAATTGTTATATCACATCCGGACGCACAGGGgcgttaatttatttttgtgcaaCGTTTGTGATAGTGCTTTCGACACAAAAGCACTCCTAAACATTCATATGCGGTCGCATACTGACCCCGAACCGTTTTCGTGCTCGATTTGTGATAGCTCATTCACTATAAAAGCGCTTTTAAGCATCCATATGCGATCACACGTCGGCGAAAAACCATACGCGTGTTCAGTTTGTGATAAATCGTTCGATACGAAAACTCTATATAGTGTGCACATGCGCGCACATTCAGACAAATCGTGTTCGATTTGTGATAAAACATTCGATACTAaatcattattaaataatcacATGCGCACTCATTGTGACAAACCATACGCGTGTACAATTTGCGATAAAGCATACGACACTAAAGCACAattaaacatacatacacgcaATCATATCGCAGATAAGCACTCATGCACCATTTGTGATAAAGTATACGATACCAAAACACAATTGAACATTCACACACGCACTCACATCGCTGAGAAACCCTATGATTGTTCGATGTGTGATAAAGCTTTCGATACTAAATCACAATTAAATATCCATATGAGGACTCATAAACATTCGTGTTCGATTTGTGATAAAGCTTTCGATACTAAATCACAATTAAGTAGTCATTTACGGACTCATATCGCGGAAAAACCGTATTATTGTTCGATTTGTGATAAAGGGTTAGATACTAAATCACAATTAAGTGTTCATATGCGGAGTCATATCACAGACAAACCATACTCTTGTTCAATTTGCGATAAGGGACTAGATACCAAATCACAGTTAAGTGTTCATATGCGCACTCACATCACAGACAAACCATACGTGTGTACACTGTGTGATAAATCATTTGATACAAAAACACTCTTAAACATCCATATGCGAACGCACCCAAAAGACAAACAGTTTTCGTGTTCAACTTGTGATAAAACATTCGATATTAAAGCGCTTTTAAACATCCATATGAGGTCACACAGCGATAAATCGTATTTATGTGAGCAGTGTGATAGTTCGTTTAGCACGAAAGGTAATTTAAACAATCACATGCGAACGCACTTAGGTGATAAATCGTGTATGTATTGTGATAAGTTATTCGCAACGAAATCCCTGTTGAATAATCACATGCGAACGCACAACAGCGACAAACCATACTCATGTCAAGTGTGTGATAGTCAATTCACAACAAAAACATACTTAAACATACATCGGCGATCACATTCCGACGACGATCCATATTTGTGTTCAGTGTGTAAATGCTCGTTTAAAGAAAAGCTGCATTTGAAGTATCACATGAGGACTCATACCGGTGAGAAGCCTCACACGTGCGCCATCTGTGATCGGTCGTTCGTAGCGAAATCACTGTTGAAAGTCCATATGCGGATACACACCGGGGAGAAACCTTACACGTGTACAGTGTGCGATAGTTCGTTTAAAATGCTACATCATTTGCGAGGGCACATGAGGACGCACACGGGGGAAAAACCGTTCGCGTGCACCGTGTGCTTTAAGTCGTTCGGACAAAAGTATGTTTTGAACATACATATGCGGCAACACACTGGCGAGAAACCGTTTGCGTGCGGTGTTTGTAATGTTACGTTTATATCGAAATCGAAATTAAAGACTCACATGCGTAAACATGATGATGATAGTTGA
Protein Sequence
MSNSHDFDIDKVCRTCLSTLNLKSLFDAYSTQDCFDEMLMICTSVECYENDGLPIQICSDCINELNRSYEFAVKCRESDTKLRLCIQNPSQCTNALNPTYKNNSIDTLETVISQNHLDSELTVNKYDLDSLDNSTTDSFEIVQEVSTVRQLKDCINLETNSDHSQEASTPQLNGVIDTKRPTTFTCSHCGSLFPNKTNLDAHTLHSCDKQYTCTICNNSFELQHQLLYHIRTHRGVNLFLCNVCDSAFDTKALLNIHMRSHTDPEPFSCSICDSSFTIKALLSIHMRSHVGEKPYACSVCDKSFDTKTLYSVHMRAHSDKSCSICDKTFDTKSLLNNHMRTHCDKPYACTICDKAYDTKAQLNIHTRNHIADKHSCTICDKVYDTKTQLNIHTRTHIAEKPYDCSMCDKAFDTKSQLNIHMRTHKHSCSICDKAFDTKSQLSSHLRTHIAEKPYYCSICDKGLDTKSQLSVHMRSHITDKPYSCSICDKGLDTKSQLSVHMRTHITDKPYVCTLCDKSFDTKTLLNIHMRTHPKDKQFSCSTCDKTFDIKALLNIHMRSHSDKSYLCEQCDSSFSTKGNLNNHMRTHLGDKSCMYCDKLFATKSLLNNHMRTHNSDKPYSCQVCDSQFTTKTYLNIHRRSHSDDDPYLCSVCKCSFKEKLHLKYHMRTHTGEKPHTCAICDRSFVAKSLLKVHMRIHTGEKPYTCTVCDSSFKMLHHLRGHMRTHTGEKPFACTVCFKSFGQKYVLNIHMRQHTGEKPFACGVCNVTFISKSKLKTHMRKHDDDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01041074;
90% Identity
iTF_01041074;
80% Identity
-