Basic Information

Gene Symbol
Trl
Assembly
GCA_000004795.1
Location
GL277973.1:645680-646629[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1e-20 8.1e-17 60.9 0.0 16 50 27 61 23 65 0.94

Sequence Information

Coding Sequence
aTGTTAATTATGATCAAACCGTGTACATTGTATCTACTCTTACTTggatttgtaaataaaaagcGAGATTGGAACTCGAAATCAAGAACATTGTCAGATCAGCCAGCAACTTGCCCTCTGTGCGGAGCGACAATAAGACAGTCTAGAAATTTGAGAAGACACTTGGAACTATTGCATTTCGGAGCTGGTTCAGGGGGTAAATCAGGATTACGAATCAAAAAAGATAAGACGGATAAATCGGTACCACTTTCGCTCACACCTAGATCACCACCTTACTCTAGAGCATCATTAACATTAAGAGACAATGCTTATTCAAAGCAAGATGCTACCGATTACTCGACGATGCCTTCCCTAAATCTGAGCTCATCAGTTGGTGCTAGCTCGTCAAATCTCAATGTCCCAGGTTCGTTCATGCTCGGAGGATCCGGAGGCTTAGGTTCCAACGATCACGGACACGGGCATCCCAGTCACCCTACCAACAACAATCCAGCCCACTCGATGTCCGCGTGTCCACCTTCGTCAATGACCCCGCACAACAATAGCATATACTCGTCCGACAGCATGTTAAGCAGTTTATTTCCGACGTTGCCCACGTTACCAACCTTGTCCTCGCCGCACGATATGTTTCGCCACTCAGAATTTTTCCGGGCGAACATGGGCTACAACCAGGACCCGTCAAGACAGCAGCACCCCGGCAGGCACATGCAACGCACAGACGTTACATGA
Protein Sequence
MLIMIKPCTLYLLLLGFVNKKRDWNSKSRTLSDQPATCPLCGATIRQSRNLRRHLELLHFGAGSGGKSGLRIKKDKTDKSVPLSLTPRSPPYSRASLTLRDNAYSKQDATDYSTMPSLNLSSSVGASSSNLNVPGSFMLGGSGGLGSNDHGHGHPSHPTNNNPAHSMSACPPSSMTPHNNSIYSSDSMLSSLFPTLPTLPTLSSPHDMFRHSEFFRANMGYNQDPSRQQHPGRHMQRTDVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01190889;
90% Identity
iTF_01035882;
80% Identity
-