Basic Information

Insect: Myzus cerasi
Gene Symbol: NUP62
Assembly: None
Location: Mc6097:852-12504[-]

Transcription Factor Domain

TF Family: E2F
Domain: E2F_TDP domain
PFAM: PF02319
TF Group: Helix-turn-helix
Description: This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 2e-28 1.9e-24 85.8 0.1 1 65 30 95 30 95 0.98

2 2 1.1 1e+04 -3.1 0.0 9 18 635 644 628 662 0.53

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	2e-28	1.9e-24	85.8	0.1	1	65	30	95	30	95	0.98
2	2	1.1	1e+04	-3.1	0.0	9	18	635	644	628	662	0.53

Sequence Information

Coding Sequence: ATGGAACTTGTAGAGAGCAGTGATGACGAAAGTTCATCATTGACAAAAATAATGACTGTTGAAGATATTCTTTTAGGCAAAGGCAGGCAAGAAAAATCGTTGGGCAACTTGGCCACCAAGTTTGCTGACCTTCTTCGAAACTCTCCAGATGGAGTAATGCATTTAAACAAAGCCACTGCCATGCTTGCTGTTAAACAAAAAAGAAGAATTTATGATATTACAAATGTACTAGAAGGTATTGGTTTAATAGAAAAAAAGACTAAAAATCAAGTTAGATGGAGGGGAGTTGAAACAAGTGAAGATGATAAGACTGCTGCAACAAGAACAAAACTTCAAGAAGAAATACAAACTTTAAAGTGGCAAGAAGATATTCTGGATAAGCAATTAGAGATTCTTAGTCGTGATTTTAAAGTGCTTAAGGAAGAAAAATCTTTTGCTCGTTACATGTATTTATTGAGCAGTGAAATCTCCAATAAACATGAAAAACGATCGGTTTTTACTGTACAACCTATGGAAGCACTTAGAGGAGCTAGCATTTCCATACCAAGAACCAAATTTAATCGAAACTATAGTATTAAACCCTTTGATAACAGTATGCCTTTTAGAATACATTTTAACTCTAAAACTGTACCAGTTAACATGAATCTTATTTCATTCAAAGCATTTGGTCAACTTGAGAATAAACGATGTGTTTCGGAATCCATTAGTAAATTAAGAAAAATACCTCGCACTAATTATTCTGATGATGTAAAAACTAGTATTGTACACAATAATGAAGAATCTGACGATATGGAAGAAATTATTGTATTGAATAAAGAAGGTAAACAGGTGGAAAAAAATATTAATTGCGATACATTAGATGATAATAGAACTAAGTCTTATGCTAGAGTTTCTCCACGCTATGATCCGATCTTCAGGTTGAGCCCACCTCCGTCAGTAAATACTTTCCCATGTTTAATTGACCCTTCTGAAGGGAGTTCAACTCAAGCTCCAGCTGGTTTCTCCTTAGGGAGTAACACCCAACCAACTTCTACCGGTTTCTCATTAGGTGGTACCACACATGCAACAACTGGTTTTTCATTAGGTAGTACCACACAAGCATCAACTGGTTTCTCATTGGGTGTTACAAACCAACCATTTACTGGCTTCTCTTTGGGGACAACTTCAGCGTCTACTGGATTCTCGTTAGCTACAACTCAAGCATCTAATGCTTTCTCATTGGGCACAAATCAAACATCAACTGCTTTCTCTTTGGGTGCAACTCCAACTGTTTCTACTGGTTTCTCATTAGCTAGTACCACCCAAGCATCTACTGGTTTCTCATTAGTTACAACTCAATCATCTGCTGCCTTACCACTGGCCACAGCTCAAGTATCAAATGCTTTCTCATTGGGCACAGCTCAAGCATCTACTGCTTTCTCTTTGGGTACAACTCCAGCAGTTTCTACTAGTTTTTCATTAGCTGGTACCACTCAAGCATCTACTGGTTTTTCAATGGGTACCACGCAAGCATCTACTGGTTTCTCGTTGACCACAACTCAAGCATCTACTGGATTCTCATTGGCCACAACCAAAGCATCAACAGGTTTCTCTTTGGGCACATCTACAGCAGTTCCTACTGGTTTCTCATTAAGTACAACAAGCAATACTGGATTTTCATTGGGCACTTCTGGAACAACCACAGCCCAAGCTACTACAATACAAACAACTGCAGCAATTACTGCACAAGCTCCACCTGTTACATCTCAATCAGATAGTCAATCCAATGCAGTTCAACCGACTAATTTCCAACAGCTTATCGATTTAATTAACAACTGGACTGTCAGTTTAGAAAATCAAGAAAAACAATTTCTTAATCAAGCAAATGAAATAACCGTTTGGGATAATATGTTAACAAACCAATCCACTAAATTGGTAAAACTGTATGATATTCTGGAGCAAAAAGAAAAAGAACAAGTAGATATAGAAAATGAACTTGACTTCTTGTTATCCCAACAAAAAGAACTCGAAGATTGTTTAGTTCCACTAGAACAAGAATTACAATCTGCTGAAGTATTAAGTAGCTTGAACAATGAAAGAGAACCAATATATAAAGCTGCTCAAGAAATTGATAACCAAGTAAAACAAATGTCTGGGGATATAAAAGAAATAGTAAACAATTTAAACAAAGCCAACTCCAAAAAAGATTCTGATGATGATTTGGATACTATTTGTCGAATATTAAACTGCCATATGACAGCATTACAGTACATAGAGCACAATGCAGAAAACTTAAGTTCAATGGTATCTGAAGTGAATGAAGAACATTCCCGCTTCTTAACAGCTGCTAATGATAATTCATTTATATCTTTTAGGAAATAA
Protein Sequence: MELVESSDDESSSLTKIMTVEDILLGKGRQEKSLGNLATKFADLLRNSPDGVMHLNKATAMLAVKQKRRIYDITNVLEGIGLIEKKTKNQVRWRGVETSEDDKTAATRTKLQEEIQTLKWQEDILDKQLEILSRDFKVLKEEKSFARYMYLLSSEISNKHEKRSVFTVQPMEALRGASISIPRTKFNRNYSIKPFDNSMPFRIHFNSKTVPVNMNLISFKAFGQLENKRCVSESISKLRKIPRTNYSDDVKTSIVHNNEESDDMEEIIVLNKEGKQVEKNINCDTLDDNRTKSYARVSPRYDPIFRLSPPPSVNTFPCLIDPSEGSSTQAPAGFSLGSNTQPTSTGFSLGGTTHATTGFSLGSTTQASTGFSLGVTNQPFTGFSLGTTSASTGFSLATTQASNAFSLGTNQTSTAFSLGATPTVSTGFSLASTTQASTGFSLVTTQSSAALPLATAQVSNAFSLGTAQASTAFSLGTTPAVSTSFSLAGTTQASTGFSMGTTQASTGFSLTTTQASTGFSLATTKASTGFSLGTSTAVPTGFSLSTTSNTGFSLGTSGTTTAQATTIQTTAAITAQAPPVTSQSDSQSNAVQPTNFQQLIDLINNWTVSLENQEKQFLNQANEITVWDNMLTNQSTKLVKLYDILEQKEKEQVDIENELDFLLSQQKELEDCLVPLEQELQSAEVLSSLNNEREPIYKAAQEIDNQVKQMSGDIKEIVNNLNKANSKKDSDDDLDTICRILNCHMTALQYIEHNAENLSSMVSEVNEEHSRFLTAANDNSFISFRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00135107;
90% Identity: -
80% Identity: -