Mimp004844.1
Basic Information
- Insect
- Mythimna impura
- Gene Symbol
- foxj1b
- Assembly
- GCA_905147345.1
- Location
- CAJHVM010000037.1:250750-252228[-]
Transcription Factor Domain
- TF Family
- Fork_head
- Domain
- Fork_head domain
- PFAM
- PF00250
- TF Group
- Helix-turn-helix
- Description
- The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 1.8 3.7e+03 -0.1 0.1 55 80 20 45 18 52 0.81 2 3 5.5 1.1e+04 -1.6 0.0 17 57 53 92 49 102 0.77 3 3 1.5e-35 3.1e-32 112.3 0.4 2 83 357 437 356 442 0.97
Sequence Information
- Coding Sequence
- aTGTTTGACAATTCTAAATTTGATAGGAATGAAGAGGCCGGTCTCGATAAAGACTTTTTAGAATTGGAGGATAAGTTTGGCAAGATTGAAGACtggaaaaataattcaagaaaggGATTTTCTTATAATTACACTCCACCACGTTTAGATGCGGAAAATTCTGCAGGTAATAACCAGTCTTTACAAACTTATCTTAATACTTTTGAAAATGATTACGAGTCTTTTAATGTTCAAGAGCCAAATTTTAATAATCGATCTACAAGAAGTTTAAGTGTGGCAGatgcaaaaaataatatatctcATCGATTTCTAGAACCAGGTGTATTCCAAAATATTTCTTCTGGAATGTACCAAGAACAAGATTTTAGAGAAAAGGCGGGATCTTTCTCTTCTTCcaataattcaaaattagaTAATCTAAAAAATGAAGAGATATTAAATCAAGTTGATGGATTAGAAAATAATGAGTTTAAAAAGGATTTAAAAGGAGCTAGGCCTATAAATACTCCTTATAAGTGTTATAAACCTGGTTCTTTTGAATCTCAAAAACAAATGTACAGTGTAAACCGACCAGCTGGTTCATGTTTGTTTAAAACACctcctttctttaaaaatgcGTACGTTGATCAGAATTTACCACAAAATTGTGGTCCAATGTCACCACCAATGATCGCAATTAATCAATTTGAAAATCAAGAAAGGCCAGTAAATTCAACGATGTTTGTTCCTGATCAGAACTCATCGTATGGATTTATGCCTTATAAGATTATTGAGAAAGATATTATACAATCTAATAGTGTTTATAAGAATCGTAATTTACCACCAAGTCCATTTAACACTTTTGgttcaatttataaaagaaGATCGTATTCAGAAGCAGATCTTAGTAAAAGTAACAATCTAAGAAACAAAATTAGAAACAATTTTGATAACGATGAAGATTTAATGACTTTGTATAAGAAAGGAAAGTTTAGTAGATCATCTTCTGAAAGTTGTATTGATCCAAGAACGTTttataaaacagaaaatttcCCAAGAGTATTCCAAACGAACAAAGAAAACCTCGCAAAACCAAGTCATTCCTATGCTCAAATTATAACTCGCGCAATTTCAAGTAGCATAGACGGTAAACTCTCTCTTGGTGAGATATACAAATGGATAGAagaaaattttgaatattatagATACGCTAATCCAGTTTGGAAAAATTCTATTCGTCACAATTTGTCGTTaagtaaatgttttaagaaAGTTCCTAGGGAACCAGGTAGTCGAGGAAAAGGCGGTAAGTGGATGATAGATAAAGAGTATTTGTTTATTGAAGAAAGTAAAAAGAAACGGAGATCTTATGGTGAGGAGAATGAGACCTTTCAGAACAATATTGATAAAAAAGATATTTGTAATGAAGGATATTTACGAAATAATATCACAACTGTTGAATACTCGAATTATGGCGAAAATAAATACGaagaaatgtaa
- Protein Sequence
- MFDNSKFDRNEEAGLDKDFLELEDKFGKIEDWKNNSRKGFSYNYTPPRLDAENSAGNNQSLQTYLNTFENDYESFNVQEPNFNNRSTRSLSVADAKNNISHRFLEPGVFQNISSGMYQEQDFREKAGSFSSSNNSKLDNLKNEEILNQVDGLENNEFKKDLKGARPINTPYKCYKPGSFESQKQMYSVNRPAGSCLFKTPPFFKNAYVDQNLPQNCGPMSPPMIAINQFENQERPVNSTMFVPDQNSSYGFMPYKIIEKDIIQSNSVYKNRNLPPSPFNTFGSIYKRRSYSEADLSKSNNLRNKIRNNFDNDEDLMTLYKKGKFSRSSSESCIDPRTFYKTENFPRVFQTNKENLAKPSHSYAQIITRAISSSIDGKLSLGEIYKWIEENFEYYRYANPVWKNSIRHNLSLSKCFKKVPREPGSRGKGGKWMIDKEYLFIEESKKKRRSYGEENETFQNNIDKKDICNEGYLRNNITTVEYSNYGENKYEEM*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01149395;
- 90% Identity
- iTF_01149393;
- 80% Identity
- -