Mimp008416.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mythimna impura
Gene Symbol
fd96Ca
Assembly
GCA_905147345.1
Location
LR990340.1:10634993-10635733[-]

Transcription Factor Domain

TF Family
Fork_head
Domain
Fork_head domain
PFAM
PF00250
TF Group
Helix-turn-helix
Description
The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.9e-39 3.8e-36 124.9 0.0 1 88 12 98 12 98 0.97

Sequence Information

Coding Sequence
ATGCCGCGGCCCTCGCGTGAATCTTACGGCGACCAGAAGCCCCCGTACTCGTACATTTCCCTGACGGCGATGGCGATCTGGAGCTCCCCGGAGCGCATGCTGCCGCTGTCGGAGATCTACCGGTTCATCACGGACCGCTTCCCGTACTACCGGCGCAACACGCAGCGCTGGCAGAACTCGCTGCGGCACAACCTCTCCTTCAACGACTGCTTCGTGAAGGTGCCGCGCCGCCCGGACCGGCCCGGCAAGGGCGCCTACTGGACGCTGCACCCGCAGGCCTTCGACATGTTCGAGAACGGCTCGCTGCTCCGCAGGCGCAAGAGGTTCAAGCTGCACACGGATCAGAAGGACAGCTTCAAGTCGGAGCTGACTGCGTTGGCGAACTTCAATCAGCAGTTTCTGGCTGGTCAGTTAAATATGAGGGTTCCTCCTTTGCAACAAGTGTTTGAAGCGCCAGTGATTGTTAATTCTTGTACAGTGACTGATAGTAAGGACAATTGGAGGAAGTCGTTTTCTATCGATAGTTTACTGAGCAGTGGAGTGGACAAGGCTAGTGTTGTGGCCGCGAGTGTTGTGCCCGCGCCGGCTCCGTTCCGGCCAGACTTGGCGGCGCTGGGTGCGGCGATGTGGCCCCCCTTCATGCCACCATCACCACTTGAACATCTTCAATTAAGACTAAACTTTCAGAACATTGTTGACAATCTGCATTTTTATCTGCAGCACCCTTTGCATTCATTATAA
Protein Sequence
MPRPSRESYGDQKPPYSYISLTAMAIWSSPERMLPLSEIYRFITDRFPYYRRNTQRWQNSLRHNLSFNDCFVKVPRRPDRPGKGAYWTLHPQAFDMFENGSLLRRRKRFKLHTDQKDSFKSELTALANFNQQFLAGQLNMRVPPLQQVFEAPVIVNSCTVTDSKDNWRKSFSIDSLLSSGVDKASVVAASVVPAPAPFRPDLAALGAAMWPPFMPPSPLEHLQLRLNFQNIVDNLHFYLQHPLHSL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01029026; iTF_01027109; iTF_01030942; iTF_00785825; iTF_00785826; iTF_00783236; iTF_01285355; iTF_00784204; iTF_01029967; iTF_00171568; iTF_00850403; iTF_00851527; iTF_00383429; iTF_01028071; iTF_00888025; iTF_00449931; iTF_01342029; iTF_00049711; iTF_00072061; iTF_01259890; iTF_01538548; iTF_00952514; iTF_00952513; iTF_00771684; iTF_00039602; iTF_00973530; iTF_00122165; iTF_00374985; iTF_01062563; iTF_00147110; iTF_00711623; iTF_00120298; iTF_01092875; iTF_00071213; iTF_01525741; iTF_00124046; iTF_00726094; iTF_00924400; iTF_00037585; iTF_00951602; iTF_01084946; iTF_00951603; iTF_01094708; iTF_00121206; iTF_00123159; iTF_01093847; iTF_00685240; iTF_00237275; iTF_01064443; iTF_01084059; iTF_00172540; iTF_00363836; iTF_00622620; iTF_00448829; iTF_00667166; iTF_00830975; iTF_01338297; iTF_01339768; iTF_00745436; iTF_00785014; iTF_00299959; iTF_01362903; iTF_01361390; iTF_01424856; iTF_00185949; iTF_00185120; iTF_01221304; iTF_00445918; iTF_00446926; iTF_00444918; iTF_00905922; iTF_01532837; iTF_01063558; iTF_00042440; iTF_00040603; iTF_00043292; iTF_00907688; iTF_01526827; iTF_01534604; iTF_00176918; iTF_00425183; iTF_00809869; iTF_00273423; iTF_00808914; iTF_00274259; iTF_01246639; iTF_01533743; iTF_00036432; iTF_00038506; iTF_01192432; iTF_01230320; iTF_01119089; iTF_00111411; iTF_01116980; iTF_01118066; iTF_00041588; iTF_00928468; iTF_01061690; iTF_00301909; iTF_00300978; iTF_00373719; iTF_00906872; iTF_00757949; iTF_01531773; iTF_01440800; iTF_01439706; iTF_00000992; iTF_00000126; iTF_01377280; iTF_00017153; iTF_00017988;
90% Identity
iTF_00301909;
80% Identity
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