Mvar004499.1
Basic Information
- Insect
- Mylabris variabilis
- Gene Symbol
- topi
- Assembly
- GCA_037464815.1
- Location
- JAZBGW010001487.1:5097-7674[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0088 0.53 10.8 4.0 2 21 90 109 89 110 0.94 2 14 7.6e-06 0.00046 20.4 0.8 1 23 146 168 146 168 0.98 3 14 0.0019 0.11 12.9 0.9 3 23 176 196 175 196 0.95 4 14 2 1.2e+02 3.4 0.8 2 12 215 225 214 234 0.86 5 14 0.0013 0.075 13.5 1.2 2 23 263 284 262 284 0.97 6 14 0.43 26 5.5 0.1 1 20 290 309 290 311 0.87 7 14 0.0015 0.093 13.2 2.7 2 22 327 347 326 350 0.88 8 14 0.0029 0.17 12.4 2.0 1 23 460 483 460 483 0.97 9 14 0.11 6.9 7.3 0.3 1 23 487 509 487 509 0.96 10 14 2.1e-07 1.3e-05 25.3 2.4 1 23 515 537 515 537 0.97 11 14 0.021 1.2 9.7 0.2 1 23 543 568 543 568 0.96 12 14 0.03 1.8 9.2 2.7 1 23 574 596 574 596 0.86 13 14 4.5e-05 0.0027 18.0 0.5 3 23 604 624 602 624 0.97 14 14 0.32 19 5.9 5.7 1 23 630 653 630 653 0.95
Sequence Information
- Coding Sequence
- aTGAACATTTCTAGTAATGAAAATGGTGTACAATTTTCACTAATCAGTATTAATTATACTTCGTCTGATAATCACGCTTATTCAACACAATACTGTATTGATACGTTAACTTATCTATTAGTATGGAGAAAacgaattttcgattttaatttacaagatGAAATAAAATCTGAGACAAATTCAAACCATATTGGtatgataaaaatgataaatttagaTGACTTAGGATTGTTTATTCATAATCCATTAAAGATACCAACAATGATGCGTTGTCAGAACTGTGAAACAAATTATTCTACCAAATATCAATATCAACGACATCAATGCAAATTTAATGCTGAGAAAGTTGTATTGAAACCGAACGTTTACTTACCAAACGTggaaaataatagtaataatcatGACAATGAGAGCAACAGAAGAAGTAAAACAAAGTATGAATGTAATGtttgtaataaacaatttgttaGTATAACGAATTTAGAGCGACATCGGTCATCCCATGAGAATCCACAAGACAATATCTGTGATTATTGCAATAAGAGATTCGTCAGTGAGAATCGTTTACGGATACACAAAGAGAATCATTGTAAGAAAGCTGGTGACTTATTGAAATTCTATCGTACCGATATCACTGTGTGGAAATGTTGTAAATGTCAACAAGTCTTTTCATCCGATGAAATAGTTAATAATCATTATGAATCATGTAGTAACGAATTTTTCGATATTCCAACAACGAAAactgaaaatgaaaaaattgaaaagatcTCAACGGAAATTCTATTACAATGTGAATTTTGTAATCGTACATATGCtgataaaaatattctattgAAACATCAAAAAACACATTCAACTGATCGAAATTATGAGTGTGCTATTTGTAAAGAAATATTCGATTCATATATAACAGCAACACAACAttggttaaaaaaatgttCCGAAAATACCAATTCATTTCCTTTGCCAAAATTAATCTATTGTGAATATTGTGATCGTACATTTAAATCACACGAGTTATTATACTCgcataaaattaaaaagaaacactACACACAGAAAATTCATGTGaataatgatgaaattaattcgaattctacaaaacaaacaatcaaaaatgaatttacaatcaataaattaattgaagatgTCTTGATAGCTTTAGAAATACCCTTGAATCAAAAGatcaataatcataataatagtaataataataatagcaatgaTAATAaggaaatgataaaaattaaaaacgaacCAGAAGAAGATACAAATGGTGACAAAACCATTGAAAAAAGGAAACGTGGacgtaaaagaaaattaactcATCAACAATCGTCTGAAAGTAAAACAATTCGTCTAGAAAATGGACTTGTATACCAATGTGAACGTTGTGTacaaattttcacaaatacaACAGATTTAGAGACACACCATAAACAGGAACATGCAGCTACTTTCAATTGTGATGAATGCTCACAGgtGTTGCATAGTGCACGGGCACTTTTAATCCATAGTCGTGCCCATAAGAATCTCAAACCATTTATGTGTGAAATTTGTGGTAAAAGTTATTCGCAAACATCACATTTATGGCAGCATATGCGTTTTCATCaagGGATTAAACCATTTGCTTGTCCACATGAAGGTTGTGAAGCCCGTTATACGATACGGCCGGATTTAAAAGATCATATACGTAAAGTTCATACAAGGGAACGTCCATTCAAATGCAATGTTTGTGGGAAATGTTTTCTAACTGGTAgtgtttattatcaacatcgTTTGATTCATACAGGTGATCGTCGATATGGATGTGATATGTGTGATAGAAGATTTTTCCGTGCCGATGCtttaaataatcataaaagAATCCATACAAATGAACGTCCATATCCATGTTTTGTTTGTGGAAGATTATTTCGACAGAAAGGTGATTGTAACAAACATTGCCGCACCCAACATCCTGATGctatacataattaa
- Protein Sequence
- MNISSNENGVQFSLISINYTSSDNHAYSTQYCIDTLTYLLVWRKRIFDFNLQDEIKSETNSNHIGMIKMINLDDLGLFIHNPLKIPTMMRCQNCETNYSTKYQYQRHQCKFNAEKVVLKPNVYLPNVENNSNNHDNESNRRSKTKYECNVCNKQFVSITNLERHRSSHENPQDNICDYCNKRFVSENRLRIHKENHCKKAGDLLKFYRTDITVWKCCKCQQVFSSDEIVNNHYESCSNEFFDIPTTKTENEKIEKISTEILLQCEFCNRTYADKNILLKHQKTHSTDRNYECAICKEIFDSYITATQHWLKKCSENTNSFPLPKLIYCEYCDRTFKSHELLYSHKIKKKHYTQKIHVNNDEINSNSTKQTIKNEFTINKLIEDVLIALEIPLNQKINNHNNSNNNNSNDNKEMIKIKNEPEEDTNGDKTIEKRKRGRKRKLTHQQSSESKTIRLENGLVYQCERCVQIFTNTTDLETHHKQEHAATFNCDECSQVLHSARALLIHSRAHKNLKPFMCEICGKSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCGKCFLTGSVYYQHRLIHTGDRRYGCDMCDRRFFRADALNNHKRIHTNERPYPCFVCGRLFRQKGDCNKHCRTQHPDAIHN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00813902;
- 90% Identity
- -
- 80% Identity
- -