Basic Information

Insect: Hycleus cichorii
Gene Symbol: topi
Assembly: GCA_013841215.1
Location: JACDRQ010000125.1:25549-28100[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0056 0.38 10.8 4.0 2 21 89 108 88 109 0.94

2 14 1.3e-05 0.0009 19.1 0.8 1 23 144 166 144 166 0.97

3 14 0.0012 0.079 13.0 0.8 3 23 174 194 173 194 0.95

4 14 1.3 92 3.3 0.8 2 12 213 223 212 233 0.79

5 14 0.00044 0.03 14.3 0.9 2 23 260 281 259 281 0.97

6 14 0.27 19 5.5 0.1 1 20 287 306 287 308 0.87

7 14 0.00091 0.062 13.3 2.8 2 22 324 344 323 347 0.88

8 14 0.0018 0.12 12.4 2.0 1 23 448 471 448 471 0.97

9 14 0.073 4.9 7.3 0.3 1 23 475 497 475 497 0.96

10 14 1.4e-07 9.2e-06 25.4 2.4 1 23 503 525 503 525 0.97

11 14 0.013 0.88 9.7 0.2 1 23 531 556 531 556 0.96

12 14 0.019 1.3 9.2 2.7 1 23 562 584 562 584 0.86

13 14 2.8e-05 0.0019 18.1 0.5 3 23 592 612 590 612 0.97

14 14 0.2 14 5.9 5.7 1 23 618 641 618 641 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0056	0.38	10.8	4.0	2	21	89	108	88	109	0.94
2	14	1.3e-05	0.0009	19.1	0.8	1	23	144	166	144	166	0.97
3	14	0.0012	0.079	13.0	0.8	3	23	174	194	173	194	0.95
4	14	1.3	92	3.3	0.8	2	12	213	223	212	233	0.79
5	14	0.00044	0.03	14.3	0.9	2	23	260	281	259	281	0.97
6	14	0.27	19	5.5	0.1	1	20	287	306	287	308	0.87
7	14	0.00091	0.062	13.3	2.8	2	22	324	344	323	347	0.88
8	14	0.0018	0.12	12.4	2.0	1	23	448	471	448	471	0.97
9	14	0.073	4.9	7.3	0.3	1	23	475	497	475	497	0.96
10	14	1.4e-07	9.2e-06	25.4	2.4	1	23	503	525	503	525	0.97
11	14	0.013	0.88	9.7	0.2	1	23	531	556	531	556	0.96
12	14	0.019	1.3	9.2	2.7	1	23	562	584	562	584	0.86
13	14	2.8e-05	0.0019	18.1	0.5	3	23	592	612	590	612	0.97
14	14	0.2	14	5.9	5.7	1	23	618	641	618	641	0.95

Sequence Information

Coding Sequence: ATGAATATTGCTGGTAATGAAAATGATGTACAATTGCAAATAATTCGAATTTATTATACTTCATCTAATAATCAGACTTATTCAACGCAATACTGTAGTGATACTTTGACTTGTATGTTGGTATGGAGGAAGCGAATTTCCGATTACCATCTACAAAATGGAATAAAATCGGAGACAAATACAGATAATGGTGCAATAAGAATGATAAATTTGAACGATTTAGGATTACTGATTCATAATCCATTGAAGATACCGACAATGATGCGTTGTCAGAACTGCGAAACGAATTATTCGACCAAATACCAATATCAGCGGCACCAGTGCAAATTCAACGCCGAGAAAGTCGTCTTGAAACCGAACGTTTATTTAACGAATCTAGCCAATAATAGCAATAGTGATAATGAGGATAATAGAAGGAATAAAACGAAATACGATTGTAATGTTTGTAATAAACAATTTGTTAGTATAACGAATTTAGAGCGCCACCGATCGTCCCACGAGAATCCACAAGACAATATTTGCGAATATTGCAATAAGCGTTTCGTCAGCGAGAACCGGCTACGAATACACAAAGAGAATCACTGCAAGAAAGCCGGCGATTTATTGAAATTCTACCGGACCGATATCACCGTTTGGAAATGTTGTAAATGCGAACAAGTCTTCTCATCCGATGAAATCGTCATCAATCATTATAAAACTTGCAATGAATTCTTCCATATTCCAATAACGAAAATTGAAAACGAGAAAACTGAGAAGATATCAACGGAGATCTTGTTGCAATGCGAATTTTGTAATCGCACCTATGCCGATAAAGAGATTCTATTGAAACACCAAAAAACCCACTCGACTGATCGAAATTACGAGTGTGCCATTTGTAAGGAAATATTCGATTCGTACATCACAGCAACACAACATTGGTTGAAGAAATGTTCGGAAAATACCAATTCATTTCCATTACCGAAATTAATTTATTGTGAATATTGTGATCGTACTTTCAAATCGCACGAATTGTTATATACGCACAAAATTAAAAAGAAACACTACACGCAAAAAATCCATGTAAACAACGATGACAATAATACGAATTCCACAAAACAAGCGATTAAAAACGAGCATACTATCAATAAACTAATCGAAGAAGTCTTGGTGGCTTTGGAAATACCGTTTAATCAAAAAATTAGTAATAATAATAATGATGAGATTGATGTGAAAGTTAAAAACGAACCAGACGAGGATACCAACGGTGATAAAACCATCGAGAAACGGAAACGCGGCCGTAAACGAAAATTAACCCAAGAATCGTCCGATAATCAAACTGTCGGTCTAGAAAATGGACTTGTGTACCAATGTGAACGTTGCGTGCAAATTTTCACGAATACAACAGACCTGGAAACCCACCATAAACAAGAACACGCCGCCACTTTCAATTGCGATGAATGTTCACAGGTTTTACACAGCGCTCGGGCTCTTTTAATCCACAGTCGGGCGCACAAGAATCTCAAGCCGTTTATGTGCGAAATTTGCGGTAAAAGCTATTCGCAAACGTCGCATTTATGGCAACATATGCGCTTCCATCAAGGGATTAAACCGTTCGCTTGTCCACATGAGGGTTGCGAGGCTCGGTATACGATACGGCCAGATTTGAAGGATCATATACGGAAAGTCCATACGAGAGAACGACCATTCAAATGTAATGTTTGTGGGAAATGTTTTCTAACTGGTAGTGTTTATTATCAACATCGTTTGATTCATACAGGAGATCGACGATATGGATGTGATATGTGTGATAGAAGATTTTTCCGTGCTGATGCCCTAAATAATCACAAAAGAATCCATACAAACGAACGTCCATACCCTTGTTTTGTTTGTGGAAGATTATTCCGCCAGAAAGGTGATTGTAATAAACATTGCCGCACCCAACATCCTGATGCTATCCGTAATTAA
Protein Sequence: MNIAGNENDVQLQIIRIYYTSSNNQTYSTQYCSDTLTCMLVWRKRISDYHLQNGIKSETNTDNGAIRMINLNDLGLLIHNPLKIPTMMRCQNCETNYSTKYQYQRHQCKFNAEKVVLKPNVYLTNLANNSNSDNEDNRRNKTKYDCNVCNKQFVSITNLERHRSSHENPQDNICEYCNKRFVSENRLRIHKENHCKKAGDLLKFYRTDITVWKCCKCEQVFSSDEIVINHYKTCNEFFHIPITKIENEKTEKISTEILLQCEFCNRTYADKEILLKHQKTHSTDRNYECAICKEIFDSYITATQHWLKKCSENTNSFPLPKLIYCEYCDRTFKSHELLYTHKIKKKHYTQKIHVNNDDNNTNSTKQAIKNEHTINKLIEEVLVALEIPFNQKISNNNNDEIDVKVKNEPDEDTNGDKTIEKRKRGRKRKLTQESSDNQTVGLENGLVYQCERCVQIFTNTTDLETHHKQEHAATFNCDECSQVLHSARALLIHSRAHKNLKPFMCEICGKSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCGKCFLTGSVYYQHRLIHTGDRRYGCDMCDRRFFRADALNNHKRIHTNERPYPCFVCGRLFRQKGDCNKHCRTQHPDAIRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00814601; iTF_01022464;
90% Identity: iTF_00814601;
80% Identity: -