Mvar003992.1
Basic Information
- Insect
- Mylabris variabilis
- Gene Symbol
- Hr39
- Assembly
- GCA_037464815.1
- Location
- JAZBGW010001228.1:10139-13826[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.2 1.7e+03 -2.0 0.7 61 88 22 49 4 83 0.45 2 4 0.017 1.5e+02 1.5 14.9 45 177 240 374 138 380 0.78 3 4 3.6e-10 3.1e-06 26.8 0.0 1 115 443 544 443 575 0.74 4 4 2.9e-72 2.5e-68 231.3 0.1 205 408 586 784 565 784 0.97
Sequence Information
- Coding Sequence
- ATGGCCACAGATATGAGGTCACCAAATGTATCTGTCACCCCGATTAATATGGAACCATCACCatatcatcaccatcattcacatcatcaccatcatcaacaattacaatcGTCATCGACAACAATAAATGAACCACAACGGACTAGAAGTGCTCCGCATCCTAATTTATTGACGAATGGTGATGTTTTGGATAATTCAGCTGATGCTGAAGTGGCACAAATCGATTTCCAATATGCTGTTAATATGAGATATAAAAAGAAACGGGATAGTGGTaacggtggtggtggtggtggtggtgttaatattaatgaaataatacCAAGACCTATGTCATGGGAAGGTGAATTATCCGATCATGAACGTGATATGTGTATTGATGATGATCACGGATCTCAGGGACCTGAGAATTTATCGTTATCACAatcgaaattaaataatacaacaataacaacaaataatttagattcaaAACATAGTCCAATATTGAGACTGAAACAACCACCAATTGGTAATTATTCATTGCATAGTACACCGAGTAATTCACCATTATTAAGTCAACGACATACAATAACtggtagtaataataataataatactagtaATAGTGGTGGTGTTGTACCAATAATCAGTCATAAAGATTTAATGCATAAGACAATAAATATACCACCGACACCAAGTCCTGATTCAGCTATACATTCAGCATATAGTGTATTTAGTTCACCAAATCAAAGTCCATTAACACAAAGACATATAACATTAACACCAAATTTGAGTCGAAATAATAGTGATGCATCACATTCAAGTTGTTGCAGTTATTCAAGTGTTTCAGTATCTGTATCACCAACACAACAATTTTCACCTACACACAGCCCGATTCAGgGTCGCCATATGCACAATATCCATAATAGTCCTTTACATCACAATGTATTATATAGAAGTTTACAAGAGAATGAGACAATACAATATAATAATCATGAACATGATGGTCTCGATGAGACTGAAGATAATAAGACTGGTTTAATACatacaacatcatcatcatcatcgtcatcatcatcggcAACATCATCATTACCAGCCCAACCGGGTATATCACGACAACAATTAATCAATAGTCCATGTCCTATATGTGGTGATAAAATATCTGGCTTCCATTATGGTATATTTAGTTGTGAATCATGTAAAGGTTTCTTTAAACGTACAGTAcaaaatcgtaaaaattatGTATGTTTACGTGGTGCTGCATGTCCTGTTACTGTTGCAACACGTAAAAAATGTCCAGCATGTCGGTTTGATAAATGTCTACAATGCGGAATGAAACTTGAAGcTATTAGAGAAGATCGAACTAGAGGTGGACGATCAACTTATCAATGTTCATATTCTTTACCACCATCATTAACAAATCATGCTGAATTACGGTCAAGTACAACTGATTTACGACAGAATCTTAACGATCCACATCATGGTAATTTGACTGTGAAATTGGAACCTAACGATTCTGGTCTGTTATCAACATCagcattaacaacaacaacacatcaTAAACGTAATAGTGGAACTGTACCGGGTTCAAAAGGTGTCCCAGCATTATTGCAAGAAATAATGGATGTGGAACACCTATGGCACTATAATGAAGtcgaattgaataaattaagcACAGAAGGACATTTAGGTAAAGAAGGCACAAGCGGTGCCGTCCATAATCTGTCAAATCATCCACTTCTAGTCGGTACAGCATTCGCCGGTTCAACAGATACAAATCCTGATTTTGTTGCTAATTTGTGCAATATCGCCGATCGAcgattatataaaattgttaaatggTGTAAAAGTTTAccattattcaaaaatatatcgatcGACGATCAGATTTGTCTGTTAATCAACTCATGGTGtgaattattgttgttctcTTGTTGTTTCCGTTCAATGTCCACACCTGGTGAGATTCGTGTATCGTTAGGTAAAAGTATAACATTGAATCAAGCCATCGATATGGGTATGCAAGCATGTATTGAACGTATGTTGAATTTTACTGAACAATTACGACGTTTACGTGTCGATCAATACGAATATGTAGCAATGAaagttattgttttattaacatcagaTACATCAGGATTGCGTGAAGCGGAAAAAGTACGTGTTTCACAAGAGAAAGCATTAAAAGCATTACAAGATTATACATTAAGCCATTATCCAGATAGTCCAGCGAAATTCGGTGAATTACTATTACGTATACCTGAATTACAACGTACTTGCCAAGTTGGTAAGGAGATGTTGACGATTAAATCAAAAGATGGCGATGGTCCCAGTTTTAATCTATTGATGGAACTGTTACGTGGAGATCATTAG
- Protein Sequence
- MATDMRSPNVSVTPINMEPSPYHHHHSHHHHHQQLQSSSTTINEPQRTRSAPHPNLLTNGDVLDNSADAEVAQIDFQYAVNMRYKKKRDSGNGGGGGGGVNINEIIPRPMSWEGELSDHERDMCIDDDHGSQGPENLSLSQSKLNNTTITTNNLDSKHSPILRLKQPPIGNYSLHSTPSNSPLLSQRHTITGSNNNNNTSNSGGVVPIISHKDLMHKTINIPPTPSPDSAIHSAYSVFSSPNQSPLTQRHITLTPNLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHMHNIHNSPLHHNVLYRSLQENETIQYNNHEHDGLDETEDNKTGLIHTTSSSSSSSSSATSSLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTVATRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTNHAELRSSTTDLRQNLNDPHHGNLTVKLEPNDSGLLSTSALTTTTHHKRNSGTVPGSKGVPALLQEIMDVEHLWHYNEVELNKLSTEGHLGKEGTSGAVHNLSNHPLLVGTAFAGSTDTNPDFVANLCNIADRRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLNQAIDMGMQACIERMLNFTEQLRRLRVDQYEYVAMKVIVLLTSDTSGLREAEKVRVSQEKALKALQDYTLSHYPDSPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGDGPSFNLLMELLRGDH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00753059;
- 90% Identity
- iTF_00813755;
- 80% Identity
- iTF_01022262;