Mnit005917.1
Basic Information
- Insect
- Musotima nitidalis
- Gene Symbol
- MBD-R2
- Assembly
- GCA_949126915.1
- Location
- OX421417.1:15015719-15036078[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.6 9.4e+03 -2.8 0.0 46 75 594 623 591 625 0.84 2 2 7.9e-12 2.9e-08 34.1 0.0 5 58 745 798 741 831 0.89
Sequence Information
- Coding Sequence
- ATGGCTGTTAAGAAATGTTGTATTGAAGACTGTAGCTCATGTTCCTCAAGAAGTGAGGACGCAGGTGTAACCTACCACAAATTTCCTAAAGATGTTTCAATAAAAGACATATGGCTAAGTGTTACCcgaaaaaatcataataatgatGACACAACTGCATATGTATGCTCTCGTCATTTCTGTAAAAGTGATTTTAAGATTTACAAGGATTCCAAATATGTACTGAAGTCAGatgCTATACCTTCAATATTTCCCTGGATAAAAGACGAAAGTCTAgcagtaaaaattaaaatggagCCTCCAGAACAGATAAGCGaaacattaaataatagtaaagaaTCTGAAGGAGAAACAGTAGATGCTATTACAAAGTTTATTGAGCAAAATGAAGATGTGGCTGAACCATCATCTTCTAATAAGACAGAAGACACTAGTTCTATTCAGAAGGATAAAGTACCAGATGAGGGGAAAGATTTTGATGAACGAATGGCTGTGGCCTCGAGTATGATGGACATGATCATTAATGAAACTGAGACGAGGGTCTCTAAAAAGAAAGGAGGGAAGCCTGCAACTAAACCATCTGGTTCTCAAGatgaaaaagGCACTACCACAATGGCACTATCAATAGGTTCAAAAGTAGAGGCCAAAGATTATGCAGAGCAATGGCATCCTGCTGAAATAGTTGAAGTAGACTATGATGAGATGGAAGTGCTGGTGCATTATAAAGACGTTACTAAAAAACATGACGAATGGATAAACGTTAGCAGTCCAAGATTAAGACCACAAACATTTTCACCTAAGGCACTACAATTAAAATCTACTACAACCGCTGCTAGTACTACAAGTACTACAATTACTGCAGCTAGTACTTCTAACAGTATTGGTACTGATAAcactattaatattaaaagcaaTGATGTTAGTACTAGTAGTCTAGTACCAGTAATAGCTGCTAAAGATATAAAAGAGGAACCTAAAGCAGTATTGGAGGAAAAACAAAAACTGATGTTCAGTGTGGGAGAGAGATGCCTAGCTAGATGGAGAGACAACAGGAGGTTTATGGCAACCATTAGCAGTGATTTAGGAAATGGaagttatgaaataatgtttgATGATGGCTTCAAATGGACGTGTCCTACAGCTAGGCTGAATAAAACTAAAGACTCGGGAAAAGTTGACGGTGTTGAGTCTGGAGTTTCTCCCGCCCAATACGGAGCCGGACCAAGCACCGCCGTGCCGACCGCGCCTGCCTTCCACACACACCTATTTGACCCCACCCGCGATTATCTAGGTTCAAAAAGCGAACGGCGTGAAATGAAACGCAAGCTAAATATAAAGGAAATATTTAACATTGGACAGAAACGACATAAGAAGAATGCTGAGAAACCAATTAAAGTTGAAAAGAAGCCTAATATATTGAGAAAGAAACCTCAAGTTTCAGTTTCGCCGAAAACTGAAATCCCAGatgcAGTAGCTTCAATAATTGGCACTGTCAAAAATGAAATAGTTTCTGAAAAACAAGAAGAAAAAATAGTTTCTGAAAAAAAGGAAGAGAATAATAAAGAAGATACTAAAGTCATAGAACCAGTTGTTAAAGAAGATGTGGATGAAAAGAAAGATATTCAATATGTAGAAGATGAAAGCATGGAAGTTTCTCTGATTGAAGTTGACAATGCAGAGAAAGAAGATTCTAACTCTAGTGATCCCGTTCAAAAAGAGGAGGTGAAACTTCAACAATTCGAGAAACCAGATGACACGAAACAAGAAGTAATAAATAGGATAAAAGaggttattaataaattagagGACGGTATAAATAAAGTAGAAAACACTCCTAaagtatttgaatttaaatctgAAGAGGTGATAGAAGAGAAAGCTGAAGAAAAATCAGAGGTGGTTGTTACTAATGAAGAGACGTCTTCAGCTGTAGCTCCAGTAACGGTAAAGAGTAAAATCTCTAAGTTAAAGAAGAGTAAAAAGTTAAGATTATTGCAGCAGAAGCGAAGTGTAAAGAGGGAGGTGGAACGAGCGCGTAGCGAGTTAGAGGTGATGAAGCGGCAAATAGCGGAGATGAGACAACAGATGATGGCCACAACCGCGCCTAAGATTACAGAGCTGTTGCCCGGTGAATGGGCGTGTCGATGGGTGAACGGGCAGCCAGTGGGTCGCGTTTGTCAGCTGGACGATGGGCGGGATGTGAAAGTGGGCGGATTGCCGCGGCGCAGCGTCCAGGTTGAAGACGAAAGGTTGCCACCAGGATGGACTAAGCATATGGTTCGCCGAAGCCTGGGCCACTCGGCGGGAAAATGGGATGTCGTTTTAGTCAATGGTGAAAACAGAAGATTTCATACAAAAACGGACATGCGGAACTACTTGGAGAACAATCTTGACGAGGCCCTGCGCCAGTACGAGCCTGTACTGATGGACTTTGGAGTACATCTCAAGCTAGCCAGGAGGCTTGGATGGTATACTACTACACCAGATGGTGTGGTGGACGATACACCAGTGATACATCTGCCGGCTGGAACTTTACCCAGTACCTCGCCTCTAGTGAAAGCGAAGAAACTTAGCATGAAAAAGGTGCGCACGGAGAAAGAAAAGGACAAATTCaagattaaaaagaaacaaGGGCTTTCTATAAGAATGCCGAAATACTTGattgccACTGGAAAAAAACAGAAAAGTAAAAGGTTTTCAGAACCTGACCCAGCCGGTTTACCACCCGCTGATTCTACATTTGACAGTCCTTTAGAAGATGGCTATGtATACGTCGGCTCATTGAAAGTGCAAATAATTGAGAATCTCTTACGATGTCCAGCTGAAGGCTGTTTCAAAAACTTCAGGAACAATACGTTAATAAAAATGCATATTAAACACTACCACAAAGAACTTCGCAAGATGCTCGGCAAGACGCCTAAAGTACTCGACTTAGCGCACGAGAGAGCGATCCCTCACATTCTCAAACAGGGAAAGAAAGATTCTacttttaaaaagattaaagttaaaataaccaAACCAGCCAAAGAGCCTAAACTTGAAATCAAGGAAGTAGAAAAAATTGATGATACAATTATTCCTAGTACAATGCCTGTTAAATTAGAAGACTCGGAACTTATAGGCATATCGCCTAAGGTACCAGATTCGCCCAAGCTCAGACAAGCGTTGGCAAACAAACCAGTGAAAAGACCTCGCGTCTTATTACCTGTACGTCGACCAGAGCCAGAAATACCTGAAGTGGGTATAGTACCAAAGATACCTTGTGATTCTACCGTTGACGATCCAGAGATACCCGCATTGGACTTTGAAACTGCGATTTCCACCCATACGGTTACAAAACCAGCTGATTTTGATGTTAAGAGGAAGCTTCAACCGTTAAAGACTGTTAGTGAGGAAGAGGATTGGTTCAATATGACGTCAGATATGGAGACAAGGTCTAGCTTCCCTAGGTCTGTCTCCCCTGAATCGAAACCTGCGCAGCTAAAGGCACAAACAGAGTCCGCTGAAGAGCAGAAGAATTCGAAGACGTATATGTTTACGGAGACGGGTGAACGCATAAAGATCGTGCATATGAAACGTGAGGAGATTATTAATTGCCACTGCGGGTTTCGCGAAGAGGACGGCCTTATGGTTCAGTGCGAACTGTGTCTCTGTTGGCAACACGCCCTTTGCCATAACATACAGAAAGAGTCtgagGTCCCAGAGAAGTACACTTGCAGCATTTGCCTGAACCCTCGCAGGGGTCGTCGCTCGCAACGTTTCCTTCACGATCAAGACCGTCTCTACGAAGGTCTGCTGCCCGGAGCCAAGCCTAAAGAGGCTTTGAGGAGGTCTCATGAGCTCAGTGGGAATCTGCTGAGAATTATGGACGCTCTACACGCCACGCGGGTGAAATACCGGGCTGCTACTAAAAAGAACCACCCCAAGCTGTACCTCTGGGCCCAAGACTGGGAGAACGGCGAGCTGGCTCTCACCCAAGAGTTGCTGAACTCTGATTACTCCGACCTCAATGTTATCATGACCTCCCTCGACAAGGAGAACCTGCCCATCAGGCCTGAGGACTTAAAGGACCCGCAGATGGATATAAATACGCCGCCTTCTGAAGAACATGATAGATATAACCAAAGAGAGGGTTCTTTTGGTACTCCTTCGCTACTGAGCGGGTTGTTAGCGAGTCCCGGCGGCGCTTCCCTGGAGCTGCCCATCAGCACTTCGGAACTGGAGCGGTTCGCACAAACCGTGCAAGAAGAGGTCCAACGCGTATCAGCTCCCCAGCCCGAAGCACCAATAGAGAACGGCGCCTGTCGGAAGAGGTTACTGAAACACATACAGCGATGTCAGGCCGTCATAGACGCGCGACTCGACTCCATAGAGGCACAGGTCGCGGAGTTGGAGTCAGAAGACCCGTCCTTTGAAGACGACGAGACAGCAGACTACTTGCCCCGCACAAAGCAGACCATACAGATGCTTTTAAGAGACCTGGATAACATGGAGGAACTTGGAGTCATCACTTAA
- Protein Sequence
- MAVKKCCIEDCSSCSSRSEDAGVTYHKFPKDVSIKDIWLSVTRKNHNNDDTTAYVCSRHFCKSDFKIYKDSKYVLKSDAIPSIFPWIKDESLAVKIKMEPPEQISETLNNSKESEGETVDAITKFIEQNEDVAEPSSSNKTEDTSSIQKDKVPDEGKDFDERMAVASSMMDMIINETETRVSKKKGGKPATKPSGSQDEKGTTTMALSIGSKVEAKDYAEQWHPAEIVEVDYDEMEVLVHYKDVTKKHDEWINVSSPRLRPQTFSPKALQLKSTTTAASTTSTTITAASTSNSIGTDNTINIKSNDVSTSSLVPVIAAKDIKEEPKAVLEEKQKLMFSVGERCLARWRDNRRFMATISSDLGNGSYEIMFDDGFKWTCPTARLNKTKDSGKVDGVESGVSPAQYGAGPSTAVPTAPAFHTHLFDPTRDYLGSKSERREMKRKLNIKEIFNIGQKRHKKNAEKPIKVEKKPNILRKKPQVSVSPKTEIPDAVASIIGTVKNEIVSEKQEEKIVSEKKEENNKEDTKVIEPVVKEDVDEKKDIQYVEDESMEVSLIEVDNAEKEDSNSSDPVQKEEVKLQQFEKPDDTKQEVINRIKEVINKLEDGINKVENTPKVFEFKSEEVIEEKAEEKSEVVVTNEETSSAVAPVTVKSKISKLKKSKKLRLLQQKRSVKREVERARSELEVMKRQIAEMRQQMMATTAPKITELLPGEWACRWVNGQPVGRVCQLDDGRDVKVGGLPRRSVQVEDERLPPGWTKHMVRRSLGHSAGKWDVVLVNGENRRFHTKTDMRNYLENNLDEALRQYEPVLMDFGVHLKLARRLGWYTTTPDGVVDDTPVIHLPAGTLPSTSPLVKAKKLSMKKVRTEKEKDKFKIKKKQGLSIRMPKYLIATGKKQKSKRFSEPDPAGLPPADSTFDSPLEDGYVYVGSLKVQIIENLLRCPAEGCFKNFRNNTLIKMHIKHYHKELRKMLGKTPKVLDLAHERAIPHILKQGKKDSTFKKIKVKITKPAKEPKLEIKEVEKIDDTIIPSTMPVKLEDSELIGISPKVPDSPKLRQALANKPVKRPRVLLPVRRPEPEIPEVGIVPKIPCDSTVDDPEIPALDFETAISTHTVTKPADFDVKRKLQPLKTVSEEEDWFNMTSDMETRSSFPRSVSPESKPAQLKAQTESAEEQKNSKTYMFTETGERIKIVHMKREEIINCHCGFREEDGLMVQCELCLCWQHALCHNIQKESEVPEKYTCSICLNPRRGRRSQRFLHDQDRLYEGLLPGAKPKEALRRSHELSGNLLRIMDALHATRVKYRAATKKNHPKLYLWAQDWENGELALTQELLNSDYSDLNVIMTSLDKENLPIRPEDLKDPQMDINTPPSEEHDRYNQREGSFGTPSLLSGLLASPGGASLELPISTSELERFAQTVQEEVQRVSAPQPEAPIENGACRKRLLKHIQRCQAVIDARLDSIEAQVAELESEDPSFEDDETADYLPRTKQTIQMLLRDLDNMEELGVIT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01020378;
- 90% Identity
- iTF_01020378;
- 80% Identity
- iTF_01020378;