Mnit001271.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Musotima nitidalis
Gene Symbol
egg
Assembly
GCA_949126915.1
Location
OX421413.1:25460476-25499910[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 0.077 2.8e+02 2.0 0.0 12 38 1586 1626 1576 1629 0.86
2 2 1.4e-11 5.2e-08 33.2 0.0 4 74 1658 1721 1655 1724 0.84

Sequence Information

Coding Sequence
ATGGAATCAGTTGATAAAATTCATCCTCCTCGTCGTGTTTCTGAAGAAAAAGATAATAGCGAGCATTCAGATGGCGTTTCACCTAATAGAGAAAAACATCAAATTTCTGACAAAGTATCAAATCCTGATCCCTCAGAATCATTTGACTTACCTGTTCAAACTGAACAGAGGCAAAGCGACACAGTCGCACTGACAACAGTTAGCGCGGAGCTtgggaaaaataaaattactaatagTAAAGATGAAGATCTACAGCTAAAATGGGAtggcgatgatgatgatgatgatgataatgaagaagaagaagacgacGCATTGCTAAATAAGCATGATCCAATTAACAGTAATAATATATCTGATTGTATTATAAATCAAGAAAACATAGCCGCTATTACTAAAGGTATGGACAGTGATACTTACACTAATAGTAGTGATGGAGAGAATATGGTGCTTCATTGGGATGAAGATGATGAAGAAGAGATTGAGAATGATATAATATCTATCATCAAACCACCAACACCAGAGTTGATGGCACAATACTCATTaggtgaaaataatattaaggaaaCAAATGATCAAAATGTACAAATTCAAGTTGATAActctaagaataaaaataatattggaaGTGAATCTTATCAGATAGATGTAAATAAAGAAGTTCTAGAGAATGCATTGTTAGAGGATACAGACGACAATGTTGCTCAAGCTGATTCGATAAATGAACCAAATGACGATGAAACTGATGATGATGTGATTTTAATTGAGGATGACGACATTgaagaaaacaaaatagaaagTGCACTTGAATTACCAGAGTCAAGcaaaactaaaaatgttttgGATTCAAAATTTGAAACAAAATCACAGTCACCAAAAAAATCTCTGCATACACCTTTCAAAGCTTGTATAGACCATGGACTCAATAAACCAGACATGATGCTAGAAATACCTTCACAGGAGGTCATTGAATTTTTAGATGACCCCGATGTTTCTTGTAGCTTTAATGAAGCAATGACTGAAGACATAACAATAGAAGTGAATAATAGCGCAGAAATTATAAGTAAGACTAAAAAAgaacaagaaaataaatctcaaattattttaattgatgttGATGATGAAGTTTCAATAGTCAATGAAGAAGATTGCAGTGAAAAAGCAGATTTGAATATGAAACAAGGATCAGTAGGTTTATCAACTGAAACAATCTGTACAGATAAATCAATTGAAGTTACTAACATacctaaagaaaacaaaactgagGCAAGTAAtcctgtaaaaaataaaatttcttctgATCAAgatcaatatacatatttatcagACTGTGATGATAGTGGATCAGATGTAAGTTTAAATGTTGATAAAATTTTGTCTGAAATGGTTGATACAAGTATTCACATTGATAAAGATGtttctgaaaataatataacatcagAAAAATCTTCAAATGTGATGGATGTTTCcataaatatttcagaaaatCAAGTATCAACTATAGAAGGTTGCTTAGATTTGCATGAAAATAGAATTGAGGGCTATGTTTCAAAAACTAAAACCATTGTGGACGAAAAATCTACAGAAGAAATATCAGAgggcaaaattttaataaaagacatttcttttactgatttgaatttgaaatttgaatttggatcTGAAAATAACGGAAACTTAGAAACTGAGTCTTTTCCAGTAGAGGCTCCACACTCTAAAGCCATATCAAGCTTTGATAGTAAAAATACTTTTGCTGCAACAGATGTAGCACTGGGTGCTTGTGAATCTGAAAAAAGAACTTCAATGGAAGTTCAAGAATCCATAATTCCAGAAATCATAGATACAGACGACATAAAGTTACCAGAAAATGATAAAGTCACTAACTTACAAAGACAGATTAGTGTGCTATCACCTCAAAGAATAAATGAAGACTTTGCTATTCAAAAAGTTATGGATGTTGATGAGATTAGAccaaacaatattttgaaaaacgATGAAAAATCTGCTAATTCAAATAATGATGACCTGAAAACATCAGAAGTGACCAAAGATGAAGagcattttaaaaaacaatctatTTCTGCTAAAAATATTGAAGAACTTACCTCAGATTTTGAGCCACAGCCATCAACATCAAATGCAATAATAGAAGAAAAACCTTGTGAAGACAAATTAGTTGATGCTGAGGATTTAAAAGGAGAAGCTGCGAGAGCTACAGATAGTCTTGGGTTGTTTGTGGAATCAAAGAGGGTTatggatgatgatgaagaagagGAAGAAGGAGATGTAGATGGAGATGAAGAGGATTATGATCAAGATGAGAGCACCAATCAAACGATAACAGAACAATCAGGAGAAGACTCAAACCAGCCACATTCAGAAACTGAAGCGTCAAAAGAGATAGATATAGATGACAATGACGCAATATCTTCTGAAGACAAAGAGCAGGAAGACTTTCAATTTACTGTCACTGATGTAATGACTACAGTAGAGGACAAAATTGAAGAGGGAGAGACAAGTGACAGTAACATGAACGTTGATGCTGTGGTTGAATCTAAAAATAAAATAGAAGTGACAACTGAAGTAGTCTGCGATGAGCCTGCTAAAGGCATGGATAAGGATTATGAAACACAGGAAAACAAAGATGATACTGAGAAAGAAACACAGAAAAAGACTGTGGCAGGCTCGCAATTAAATGACAAAGCCACAGGAAAGTTATCTGATACCTCGGTTAACGGAGGAGACGACAAGATCACAGGATCAACAACCTCACCAAAATCAATAGAGGGACCCGATGATCAGAAAAGTGAAGGAACTgagaaaaatagtaataaaccCGTTAAAACCATGGAATTATCGGATCCTAAAACTGTGTTAAGCTTTGTGGATTTGGACGAGAGTTCCGAGGATGATGTTCAAGAAGTGAAAAAGAAAGATACTGCAGGCGCTGAGTCTAAGAATGTGGGGAATGTGGGGAACTTTTCTTTCATTTCCCCACCGAAAGAACAGAGCCCCACATCTAATGTGAAACCGATGGAAACCGCTAAAACTGCACCTTCAGAAAAGCCATCTCCCAATGAAGTTCTGGAAGTTTACAGCTTGGACTCAGATGAGGAAGACAACAACCTACCTGATAAAACAAAAGCAACGCCTCCAGAAGTGGAAGAAAAGGCCCCAGAGCCATTCATAGCGCGAGGGTCGAACAGATGTATCAACTTGGCATGCAAATCTACGGGCAGAATGAAGTATTCTGCAGCGACGCCGGCCGCCGTGGCATTTTTCGATGCATTCAAGAAGAAGAAAACAGTAGTGTGTACAGCCTGTGAGCAATTTGTCATCGATAGGAGCTTGTTATTAATTAAAGGTCTTAGAAAAAAGTCAGCTATAATGGAAATGGACATCGACAAGGTGTCTTCTGAGCTGGTGGAGATATCGGACTCGGAGTCTGAAGAGGAAAAGGAACCGCAGGAGGAAGAACGGGTGACCATTGGAACAGACGAAGCGATGTTCATAGAGAAGCAACTAGCCAGTGTGATAAATGAATCCTGGATAAATTTAGATATGGACTCTCAGCTCAACGATGCCGAAGCGGTTCTCAGTGACCAGATGAAGATCTTGGAAGcgAAGAGCGACGATATCAAAAATCTCTTTAACGAGTGTCAAGGGGCTACAGATAGTCTGCGAAATGATCTATACTCCATCTTTGAGCCTCGCAGACAAGAGTTACCGGCCTTGGTGCTCGTCGACACTCCTTCCAACAAGGCCAAACGTCGTTTGTCTAGTGGAGGTGAAATTCAAGCCAAAAGGCCCGCCATTCCCATGGGTTATGCTCCTTTGGAGAATGAAGTTAAAGTAGCGCAGACTTCTGTGGATAAACCAGTGCCTGAGACCCCTGCCTTCGACGACGATAAAGACATAGCTGTCCTGCAAGTGTCTGCCGAAGTGGCGCCGGCGTCGCTACCTCCCCCCGGCGAGATAGTGAAGCCTCCGGTGAAGGCTGGCCAGAGCGTGTTCGCGATAAGGAATACCCGTGGATCCTGGCTACCCGCCAAGGTCATCGAAATTGTCCTTAACGCTGGAGGGAGTCCAATATTCACGATGTGTCGCGTCAAGTTCACACTGCAGAAGTTGAAGCACTTCACTAAGACCCTGCCAGCGAGGTGCCTCGCATATTCAGAACCGGCTACAGTCAGAATGACTATTGGTACTCGTCTAATAGCACTCTTCAAGGACCCAGGGAACACATCGAAACGGGAACTGTTTTACTCGGGAGTGGTCGCTGAGGTGCCCAACCCAGTCAATAACTACAgATATCTAGTGTTTTTCGACGACGGTTACGCAAAGTACGTGAACCACGAAGACACTCGTCTCGTGTACGAATGTTCCCCGCTTGTTTGGGAGGAGGTCCATCCGCTGTCCCGTCAGTTTGTCCGGGAGTATTTAGTCTCGTACCCCGAGAGGCCCATGGTACGGCTACATCCCGGTCAGCACCTCAAAACTGAGTGGAACGgAAAATGGTGGCCATCGCGAGTTGTGCAGGTGGACGCATCTCTAGTGCAAGTCCACTTTGAGAAGGACAATAGGGTCGAGTGGATATACCGGGGCTCCACGCGCCTCGCTCCGCTCTACCTAGAGCTGCAAGCGGCCGAGAGACACCGCGCCAGGCCTAGGACTAAAGCACAGCCTAAGTCCGGAATGCCGTACGTCGAATATACGAGAGAGGAGCAGAACAAAGCCGGAGCGACATCGCCGCAACCACAAACTTCACAGAGAGAAACCCGCCAACGCGCCGTCGCGAAGAAATCAACCGCCGCCCCGCAAACGACGCCGGCTTCCGTACCCGAAAATCTCACCAGCCGAGTTGTGTACTATACTCCGAAGAACGCAGTGAAGCCCTACAAAATGGTGCCTCACGTCTGCGGCCCCAGGTGTAAGAGGAACGATGTGTTGGGTCTCAAAGACCTGCGTACCTACAACCCGCTCGCTAAACCATTACTCAGTGGTTGGGAAAGACAAATAGTCCGGTTCAAGTGCAACAAGGAGGTGCTATATCGCGCGCCGTGTGGTCGCCGAATCCGCAATGTGCGCGAACTTCACCGCTATTTGCGCGCCGTGCAATGCGAAATGCCAGTCGATCTTTTCGACTTTGCACCCTCCACACACTGTCTAGCTGAGTATGTGCTCAACACTTGCATCGTCGGGAAGAAGgATCTGTCGCACGGCAAAGAGAATGTGCCTATTCCGTGCGTGAACTACTTCGACGAGTCTCTGCCGGAGTTTTGTTCGTACAACACGGAACGAACGCCCACCGCCGGCGTGCCGCTGAATCTGGACCCGGAGTTCCTGTGTGGCTGCGACTGTACCGACGATTGTGTCGACAAATCCAAATGTGCCTGTTGGAAGATGACATTGGAAGGGGCCAACACCATCGGCCTAAAGGGACCCAACGTTGGCTATGTCTACAAGCGGCTCCCTGAACCACTGCCCTCTGGAATATACGAGTGTAATAGCAGATGTCGGTGTAAACAGACATGTCTCAATCGTGTGGCTCAACATCCATTGCAGTTAAAACTCCAGGTGTTCAAGACTACGGATCGAGGATGGGGAATTCGAGCGCTGAATGATGTACCGAAGGGAGCCTTCCTGTGCGTTTACGCTGGGAATCTGCTCACGGATGCTACGGCTAATATGGATGGCTTGAACGAGGGAGACGAATATCTGGCCGAACTGGATTACATTGAGGTCGTAGAGCAGATGAAAGAAGGGTACGAGGAGGACATACCCGAGGCTGATAAGAAATTAGACAGGaaAAACCAAGTTGTTAAATCAGAGGAAGAAGAACACATAAGCTCTGAAGAGGAGGTGGTAGCTAGTCAGGATGATGACTTCCAACCGGGCTACCATAGTACCAACGTCAGTGCCTTCAGCAAGCGTCTCCGCAAACGCAATAAAAAGAAGGAAAAGGAAGAAAAAGAGAAAGAAGAGAAGGAGAGAAGAGACAAAGAAGAGGCGAGCAAAACTGAGGATGACTGCATCACCATAAGTGACGATGAAGAAGTTCGGGAACCCTCCAGATTTACAGCACAGGCTGGCATGGGGTCTGATCAGTTCGTACCAAAATATAGATCTGTCCGTTCGTACTTTGGTAAAGACGAAGCGTGCTACATTATGGACGCTAAAGTTCAAGGAAACATTGGGAGATATCTTAACCACTCGTGTTCCCCGAACGTGTTCGTTCAAAACGTCTTTGTGGACACCCACGACCCCCGGTTCCCTTGGGTAGCGTTTTTCGCTCTCTGTCAGATCAAGGCAGGCACCGAACTGACGTGGAACTACAATTATGACGTGGGTTCTGTCCCGGAGAAGGTTTTGTACTGCTACTGCGGCGCCCCTAACTGTAGGGGTAGACTTTTGTAA
Protein Sequence
MESVDKIHPPRRVSEEKDNSEHSDGVSPNREKHQISDKVSNPDPSESFDLPVQTEQRQSDTVALTTVSAELGKNKITNSKDEDLQLKWDGDDDDDDDNEEEEDDALLNKHDPINSNNISDCIINQENIAAITKGMDSDTYTNSSDGENMVLHWDEDDEEEIENDIISIIKPPTPELMAQYSLGENNIKETNDQNVQIQVDNSKNKNNIGSESYQIDVNKEVLENALLEDTDDNVAQADSINEPNDDETDDDVILIEDDDIEENKIESALELPESSKTKNVLDSKFETKSQSPKKSLHTPFKACIDHGLNKPDMMLEIPSQEVIEFLDDPDVSCSFNEAMTEDITIEVNNSAEIISKTKKEQENKSQIILIDVDDEVSIVNEEDCSEKADLNMKQGSVGLSTETICTDKSIEVTNIPKENKTEASNPVKNKISSDQDQYTYLSDCDDSGSDVSLNVDKILSEMVDTSIHIDKDVSENNITSEKSSNVMDVSINISENQVSTIEGCLDLHENRIEGYVSKTKTIVDEKSTEEISEGKILIKDISFTDLNLKFEFGSENNGNLETESFPVEAPHSKAISSFDSKNTFAATDVALGACESEKRTSMEVQESIIPEIIDTDDIKLPENDKVTNLQRQISVLSPQRINEDFAIQKVMDVDEIRPNNILKNDEKSANSNNDDLKTSEVTKDEEHFKKQSISAKNIEELTSDFEPQPSTSNAIIEEKPCEDKLVDAEDLKGEAARATDSLGLFVESKRVMDDDEEEEEGDVDGDEEDYDQDESTNQTITEQSGEDSNQPHSETEASKEIDIDDNDAISSEDKEQEDFQFTVTDVMTTVEDKIEEGETSDSNMNVDAVVESKNKIEVTTEVVCDEPAKGMDKDYETQENKDDTEKETQKKTVAGSQLNDKATGKLSDTSVNGGDDKITGSTTSPKSIEGPDDQKSEGTEKNSNKPVKTMELSDPKTVLSFVDLDESSEDDVQEVKKKDTAGAESKNVGNVGNFSFISPPKEQSPTSNVKPMETAKTAPSEKPSPNEVLEVYSLDSDEEDNNLPDKTKATPPEVEEKAPEPFIARGSNRCINLACKSTGRMKYSAATPAAVAFFDAFKKKKTVVCTACEQFVIDRSLLLIKGLRKKSAIMEMDIDKVSSELVEISDSESEEEKEPQEEERVTIGTDEAMFIEKQLASVINESWINLDMDSQLNDAEAVLSDQMKILEAKSDDIKNLFNECQGATDSLRNDLYSIFEPRRQELPALVLVDTPSNKAKRRLSSGGEIQAKRPAIPMGYAPLENEVKVAQTSVDKPVPETPAFDDDKDIAVLQVSAEVAPASLPPPGEIVKPPVKAGQSVFAIRNTRGSWLPAKVIEIVLNAGGSPIFTMCRVKFTLQKLKHFTKTLPARCLAYSEPATVRMTIGTRLIALFKDPGNTSKRELFYSGVVAEVPNPVNNYRYLVFFDDGYAKYVNHEDTRLVYECSPLVWEEVHPLSRQFVREYLVSYPERPMVRLHPGQHLKTEWNGKWWPSRVVQVDASLVQVHFEKDNRVEWIYRGSTRLAPLYLELQAAERHRARPRTKAQPKSGMPYVEYTREEQNKAGATSPQPQTSQRETRQRAVAKKSTAAPQTTPASVPENLTSRVVYYTPKNAVKPYKMVPHVCGPRCKRNDVLGLKDLRTYNPLAKPLLSGWERQIVRFKCNKEVLYRAPCGRRIRNVRELHRYLRAVQCEMPVDLFDFAPSTHCLAEYVLNTCIVGKKDLSHGKENVPIPCVNYFDESLPEFCSYNTERTPTAGVPLNLDPEFLCGCDCTDDCVDKSKCACWKMTLEGANTIGLKGPNVGYVYKRLPEPLPSGIYECNSRCRCKQTCLNRVAQHPLQLKLQVFKTTDRGWGIRALNDVPKGAFLCVYAGNLLTDATANMDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDRKNQVVKSEEEEHISSEEEVVASQDDDFQPGYHSTNVSAFSKRLRKRNKKKEKEEKEKEEKERRDKEEASKTEDDCITISDDEEVREPSRFTAQAGMGSDQFVPKYRSVRSYFGKDEACYIMDAKVQGNIGRYLNHSCSPNVFVQNVFVDTHDPRFPWVAFFALCQIKAGTELTWNYNYDVGSVPEKVLYCYCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-