Mdom010521.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Musca domestica
Gene Symbol
ftz-f1
Assembly
GCA_000371365.1
Location
Scaffold18823:557361-757526[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 0.37 2.6e+03 -2.9 1.1 82 137 24 81 9 97 0.58
2 5 1.3 8.9e+03 -4.6 17.6 59 167 287 396 257 410 0.66
3 5 0.008 57 2.6 6.0 33 113 421 509 412 560 0.54
4 5 1.6e-19 1.1e-15 57.6 0.5 1 76 692 767 692 793 0.67
5 5 2.4e-70 1.7e-66 225.0 5.1 169 408 901 1133 897 1135 0.94

Sequence Information

Coding Sequence
ATGGAACATTTTTCCGTGGCCCTCTTGGCGGACAGTGCTTATGGTaatttaaacaataacaacagcaacagcaacaacaacaacaatatcaacaataaaaacaacaacatcaacaccatgcatcatcacaaagatcacatGTTGGGTGCCGGTAGCACTCCCAGCACCACGGGCTTTATGTATGACTCATCGTCGGCCCATCATCATGCCAAGCCGGAAATGACCATGGCCAAGAGTGACTATAGCTCCTTTGCCTCCTGCATTCAACAGTCGACCATGTTGGATCATCGCAATGTTGCCATAGATGCTAATCTGGATGCGGGCGTTTCGCTGGGTGCTCTGTGCGATTTGAAGTTTGGACCGCCGTCCAAtggtggggtaggaggtggtggtggcggtgtgggtggtagtccacccctcatgggtggtggCAATGCCACCACAGATGTGGAGAGCAACTTTAAAAGTCTACCACCGCTCATAACCAACATTGAGGCTACCAATCTAATGGGTGTCCTGCCCAAAGTTGTGGGCTCTTCTGGCATGGCCGTTAATGTGCCACAATTTGCTCAAATGCTATTCAGCCGAGAACAGCCACCGCCAGCTCCACCGGCGCAACCCATACAGGGTTCATATGGGGGTCATCCCCATCATCCGCACATACCAATGAAGGCTCAAGAAGTACAAAACACTGCCACAGAGACGACAACGCGTCACTATTTGCCAGGACCCGGAGGGGGAGCCATGACCTCAACGGGAGGTCTCCTGATCAATTCCAATGCCAGTTCGGAAGCCAATAATGAGGCCAGTGGGGAGACGAATTATGTCGACTTTGCCATGGTGGGTCATAATCATCATCGGGGCATTAATACGGCCAATATGGATGCTATTtctaccacaacaacaacaaccacagccagtagcaataacaacaacaacaacaacaaccatttaacaaatgatagccatataacaacaacaacagcaaccaccaccaccactcttaggaatgataacaacaacaataccatacacactgccagtaacaatcacaacaacaataatcatagtacaccaacaacaacaccaacccaGCCGCCAACTCAGCCACCGTCACAGCCGACCAGCCGCTCCCAGATGCACAGTATTGAAGAATTAGCCGCCAGTTCCTGTACGCCCACCTCATCAACCGTCGCCGCCCCAAACACCATTAGCAGCAGCCCCACCAGCATTGGAGGAGCCCTTAAGGGCTCCAACAACAGTTCAGTCACAGCTACAGCAGTACCTTCAGCCAAtgatcagcagcaacaacaacaaccacagtcTCAAAACTCGCTTGGCAATAGTCCATCCGGGgcagcaacatcacagccaacaacttctcaacaacatcagcagcatcagcaacaacaacaacatcatctgCTGAATTCATCGAATATTAGCACCGACAGCAATGATGACGACTCCATGTCCTCATCCGATGAATATATCGACATGGACTTCAATGATCGAACGGGTTATCAGGACACCACCTCCTCGCATTCACAACAGAGCGCCAACGGTGGCGCTGGTGGCAATTCCCAAAATAATGCCGCCGCTGCGGGGGGCATGGCCCTCATCAACGGTGTCGTCACCCTAAATACCGCCCAAAATTCAGCCGTCAACAGCGGTGGCGGCAATGGTGGCTCCTCGGCCTCTTCAGCCTCAGGCACTTATATGTCCCTGCTGCCACCAGCCACCTCGTCCTCGGCTCCACATTTGGGTGTATCGCAtatgggtggtggtggtggcggcggtacCAGTGCCACCGCCAGCGGTTCCACGCCGGATGTCATAGATTTCAAACATCTGTTCGAGGAGTTGTGTCCTGTGTGCGGGGACAAGGTGAGCGGCTATCATTATGGCCTGCTCACCTGTGAGTCGTGCAAGGGTTTCTTTAAGCGCACCGTACAAAACAAAAAGGTCTATACGTGTGTGGCCGAACGCTCCTGTCACATCGACAAGACGCAGCGCAAACGGTGTCCGTACTGTCGTTTCCAGAAGTGTCTGGAGGTGGGAATGAAGCTGGAAGCTGTGAGAGCCGATCGCATGCGAGGCGGCCGCAATAAATTCGGACCCATGTACAAACGGGATCGGGCGCGAAAACTGCAGGTAATGCGACAACGACAAATTGCATTGCAGGCCCTACGAACGTCCATGGGTACGGGAGATATGAAACCGACGCCCCTGTCCCCCGGCTATCAAACCTATTCGAATATGAATATCAAACAAGAAATACAAATACCTCAGGTATCCTCTCTCACACAATCGCCCGACTCATCACCCAGCCCCATTGCTATTGCCTTAGGTCAGGTCAATGCCAGCACCGGTGTGATAGCCACGCCCCTCAACGGCAGTGGTGGCAGTGCAGGTGGCGGaggcggcggcggtggtggcgGTAATaatggcagcagcaacaacaacaacagtacgaGTGATGGCATCAACCGCGTTGGCAGTGGTGGTGGCAGTGGAAATTGCCACGACACCGGTACCGGGTCTCTACAAAACGCCAGCGATTCAAAATTGTGCTTCGACTCGGGCACACATCCTTCAAGTACCGCCGATTCCATAATAGAACCTTTAAGGCAAGTcagatttttgatatattttttggatacaatttttaaatatttgatttttttgcttttttccagGGTATCACCGATGATCAGGGAATTTGTACAGTCAATAGACGACAGGGAATGGCAGACGCAACTATTTGCCCTGCTGCAGAAACAAACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGTAAAGTTTTGGATCAGAATCTATTCTCACAGGTCGATTGGGCCCGAAATACGGTGTTCTTTAAGGATTTGAAGGTTGATGATCAAATGAAACTACTACAACATTCATGGTCCGATATGCTGGTATTGGATCATTTACATCAACGCATACACAATGGCCTGCCCGACGAGACACAGCTGAACAATGGCCAAGTCTTTAATCTGTTAAGTCTTGGACTGCTCGGTGTGCCGCAACTAAGTGATTATTTCAATGAATTGCAAAATAAATTGCAAGATTTGAAATTCGATATGGGCGATTATGTGTGTATGAAATTCTTGATATTATTAAATCCAGATGTACGGGGTATTATCAATAAGAAGACAGTGTTGCAGGGTCATGAGAATGTGCAGGCGGCATTGTTAGATTATACGCTAACATGTTATCCATCTGTGACGGATAAATTCAGGAGGCTGTTAAGTATATTGCCGGACATTCATGCCATGGCAACACGCGGTGAAGAGCACTTATATTCAAAACATTGTGCCGGTAGTGCACCCACACAAACGTTACTCATGGAAATGTTGCATGCAAAACGGAAAGTGTAA
Protein Sequence
MEHFSVALLADSAYGNLNNNNSNSNNNNNINNKNNNINTMHHHKDHMLGAGSTPSTTGFMYDSSSAHHHAKPEMTMAKSDYSSFASCIQQSTMLDHRNVAIDANLDAGVSLGALCDLKFGPPSNGGVGGGGGGVGGSPPLMGGGNATTDVESNFKSLPPLITNIEATNLMGVLPKVVGSSGMAVNVPQFAQMLFSREQPPPAPPAQPIQGSYGGHPHHPHIPMKAQEVQNTATETTTRHYLPGPGGGAMTSTGGLLINSNASSEANNEASGETNYVDFAMVGHNHHRGINTANMDAISTTTTTTTASSNNNNNNNNHLTNDSHITTTTATTTTTLRNDNNNNTIHTASNNHNNNNHSTPTTTPTQPPTQPPSQPTSRSQMHSIEELAASSCTPTSSTVAAPNTISSSPTSIGGALKGSNNSSVTATAVPSANDQQQQQQPQSQNSLGNSPSGAATSQPTTSQQHQQHQQQQQHHLLNSSNISTDSNDDDSMSSSDEYIDMDFNDRTGYQDTTSSHSQQSANGGAGGNSQNNAAAAGGMALINGVVTLNTAQNSAVNSGGGNGGSSASSASGTYMSLLPPATSSSAPHLGVSHMGGGGGGGTSATASGSTPDVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQIALQALRTSMGTGDMKPTPLSPGYQTYSNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGVIATPLNGSGGSAGGGGGGGGGGNNGSSNNNNSTSDGINRVGSGGGSGNCHDTGTGSLQNASDSKLCFDSGTHPSSTADSIIEPLRQVRFLIYFLDTIFKYLIFLLFSRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHQRIHNGLPDETQLNNGQVFNLLSLGLLGVPQLSDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIINKKTVLQGHENVQAALLDYTLTCYPSVTDKFRRLLSILPDIHAMATRGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01019490;
90% Identity
iTF_01019490;
80% Identity
iTF_01019490;