Mach000994.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Morpho achilles
Gene Symbol
ZFX
Assembly
GCA_947086495.1
Location
CAMTZB010000001.1:15636430-15639698[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 2.6 2.4e+02 3.4 1.5 1 23 116 141 116 141 0.88
2 16 1.1 1e+02 4.5 2.8 1 23 185 207 185 207 0.96
3 16 2.8 2.5e+02 3.3 0.0 6 23 219 236 219 236 0.95
4 16 0.0056 0.5 11.8 2.2 1 23 245 268 245 268 0.96
5 16 3.8e-07 3.4e-05 24.9 1.7 2 23 290 311 289 311 0.97
6 16 6.6e-05 0.0059 17.9 1.0 1 23 318 341 318 341 0.96
7 16 0.00065 0.058 14.7 0.9 1 23 347 369 347 369 0.98
8 16 0.00012 0.011 17.0 1.3 1 23 375 397 375 397 0.97
9 16 0.082 7.4 8.1 0.3 1 20 403 422 403 423 0.95
10 16 0.62 56 5.4 4.3 1 23 537 559 537 559 0.93
11 16 0.00058 0.052 14.9 1.7 2 23 566 588 565 588 0.90
12 16 3e-05 0.0027 18.9 1.2 1 23 594 616 594 616 0.99
13 16 1.8e-06 0.00016 22.8 3.5 1 23 622 644 622 644 0.98
14 16 0.00039 0.035 15.4 1.7 1 23 650 672 650 672 0.96
15 16 3.2e-05 0.0029 18.9 1.7 1 23 678 700 678 700 0.96
16 16 0.0098 0.89 11.0 5.7 1 23 706 729 706 729 0.90

Sequence Information

Coding Sequence
ATGCGTACTTGCGGGTACACGCGTGTGGGTATGAACTATAAATGTGTTTTGGTATCAAGAGAAGATGGGTTGCCTCAAATAATATGCCACCAGTGCTGGGCCATGATTATGGAATGGGACAAATTTGTCAAGTACTCCCTGGAGGCTGAGCTGAGGCTGCAACAGAAGTTATCTGTGACGGAATTTTTGGACCCTgAAAGGAAACCGAAACAAGAGGGGACATTGCAAAGCGCTGAAACAACCGCACAGACAGAGGCACGCAGTTCGTTGATAAATAGCGTAGTGAGAGAGATATTGATGGATTACTTTCGTGAATTGAATATTGAGAATAATTCAGACCTAGAATATGTCTGCCATTCGTGCACCGAACGGCCCGTGTGCAAATCCATAGAGAATCTGATAAACCATTTAAAATCAATACACGGTCACCGACTGCGAAATGCGCAAACGatcaaaacttttataaaagaTAATGTCACCTTCGACGAAGTACTCGATAAAGACGATATCGATAGCGAATCGATTAACGATGCAAAGGAAAATCTACAGAATTACTGCTGTCCGTTTTGCGAGAGCGTATTCTCAGCACCGAGCCGTCTCATCTGTCACCTCAATAAACATATAGAAATATGCATCACAGACGGCGTTATCTGTTGCGAGGAGCTGTTCGTCGATAAGGTCGCTTTCGTGGAACATCTTCAAACGCACGTAACTAGGGCCGTGGACGAAAATCACAGCTGCAAGAGCTGCGGATTTACAGCAACTGACTCAGACGAGTTGCACGTGCATATAAATAAATCTCATCCCGAAGTCGAGAGACGAAAAAAGATCTCCTGCAACCCGAACTGCCAGAAGTACATCCGAGTGAAGTGCGCGGAATGCAACAAAACATTCTCCAACAAGCACAACCTTCGCGTCCATATGGAAATCCATAAAGGGACGACCGGCCAGTTCGCATGCGACAAATGCGGAAAGATATATAAGAATCGCGGGAGCCTTACCTATCATAACCGAGTGTTCCACGAGGGGATCCTCAGGTTTTACTGCTCTCACTGCGGCGAAGCTTTCCCCACGCGCATGACCAGAAACGTCCACGCACGGATACACACCGGCTCCAAACCGTTCGCGTGCGTCCATTGCGGGAAGTCTTACCGCGCGAAAAACACTCTGGACCGTCACATGGATATGCATTTAGACGTAAGGAAATATGCATGCCACATGTGCCCGAAGAAATGGACGCGACGCGTCAGCTTTGAATCTCACCTCGCGGACGGTGATCTTAAATACGTGACGGACGACAGCGCCCGGGCGTCCGACGAGGACGACAGACCCCTCGCCACTCTAGCCTCCGAACCGACGGATGCGTACCAGAAGTTTCATACGGCCCTCGTGAATTTCCGAAACCACTTCGTAACGGAACACGGCAGCGAGGAATGCTCGGACTTCTCGGACTCGACCGACTCGGAGAACGCGAACGAATTAGATTCACGCGTAGATCTGAACAGTTTCGACGATTTAACGGACTCCAATATGAGGAAGGATAAAATGGACGAGCAGACCCGCACGGAGCTCAGTCAGGCGCAAACGAAGATTAACGGGAAAGTGTATTACGCGTGCAAAATATGCGGGAAACACTTGAGCTCGACGCACACGTACGTGTTCCACAAGCGCATCCACACCGGGGAGCGGCCGTGCGTCTGCCACGTCTGCGGCAAGCAGTTCCGCGCGCCCAACGGGCTGCAGCGGCACGTCACCGAAACGCACGAGAAGCAACGTTGGTACACTTGCGTCGTGTGCTTCAATAAGTTCGCCAACTCGCAGAACCTCAAGCAGCACATGCGAATCCACACGGGCGAGCGGCCGTTCGTCTGCGCCCACTGCGGGAAGAGGTTCACGCAGAGCGGCTCGCTGCACGTGCACCTGAAGACCCACAGCGAGCATTACCCCCATAACTGTGCGGAGTGCGGCGCCAAGTTCAGGCTGCGCTCCGGCCTCACCCGGCACAGGCTCAAGCACACCGGGGAGCGGCCGCACGCCTGCGAGCTCTGCGGGAAGGGCTTCAGGCAGAAGCACGAGCTGAACGGCCACGTCCTGACGCACACTGACTCCAAACCCCACGCGTGCACCGTATGCGGCACGGCGTTCCGGCAGCGGAGAGCCCTCCGCCACCACTGCAAGCGATTGCACCAGAACGAGGCCAAGGACGTCGCCCACGCGGTCTACGACCACCTCGGACAGTACGAGGGATAG
Protein Sequence
MRTCGYTRVGMNYKCVLVSREDGLPQIICHQCWAMIMEWDKFVKYSLEAELRLQQKLSVTEFLDPERKPKQEGTLQSAETTAQTEARSSLINSVVREILMDYFRELNIENNSDLEYVCHSCTERPVCKSIENLINHLKSIHGHRLRNAQTIKTFIKDNVTFDEVLDKDDIDSESINDAKENLQNYCCPFCESVFSAPSRLICHLNKHIEICITDGVICCEELFVDKVAFVEHLQTHVTRAVDENHSCKSCGFTATDSDELHVHINKSHPEVERRKKISCNPNCQKYIRVKCAECNKTFSNKHNLRVHMEIHKGTTGQFACDKCGKIYKNRGSLTYHNRVFHEGILRFYCSHCGEAFPTRMTRNVHARIHTGSKPFACVHCGKSYRAKNTLDRHMDMHLDVRKYACHMCPKKWTRRVSFESHLADGDLKYVTDDSARASDEDDRPLATLASEPTDAYQKFHTALVNFRNHFVTEHGSEECSDFSDSTDSENANELDSRVDLNSFDDLTDSNMRKDKMDEQTRTELSQAQTKINGKVYYACKICGKHLSSTHTYVFHKRIHTGERPCVCHVCGKQFRAPNGLQRHVTETHEKQRWYTCVVCFNKFANSQNLKQHMRIHTGERPFVCAHCGKRFTQSGSLHVHLKTHSEHYPHNCAECGAKFRLRSGLTRHRLKHTGERPHACELCGKGFRQKHELNGHVLTHTDSKPHACTVCGTAFRQRRALRHHCKRLHQNEAKDVAHAVYDHLGQYEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01018808;
90% Identity
-
80% Identity
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