Mlae015245.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Monopis laevigella
Gene Symbol
-
Assembly
GCA_947458855.1
Location
OX375858.1:9236089-9253692[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.00012 0.01 17.3 0.1 3 23 120 140 119 140 0.97
2 17 1.1e-06 9.3e-05 23.8 1.2 1 23 146 168 146 168 0.99
3 17 4.7e-06 0.0004 21.7 3.6 1 23 174 196 174 196 0.99
4 17 1.4e-05 0.0012 20.2 5.0 1 23 211 233 211 233 0.98
5 17 0.00088 0.077 14.6 3.3 1 23 248 270 248 270 0.98
6 17 4.2e-07 3.7e-05 25.0 1.5 1 23 285 307 285 307 0.99
7 17 0.012 1.1 11.0 2.0 1 23 313 335 313 335 0.96
8 17 1.4e-05 0.0013 20.2 1.3 1 23 341 363 341 363 0.99
9 17 0.043 3.7 9.3 1.8 1 23 370 392 370 392 0.98
10 17 2.6e-07 2.2e-05 25.7 4.8 1 23 398 420 398 420 0.99
11 17 0.05 4.3 9.1 1.8 1 23 427 449 427 449 0.98
12 17 2.8e-06 0.00025 22.4 1.5 1 23 455 477 455 477 0.99
13 17 0.0057 0.5 12.0 0.9 1 23 484 506 484 506 0.99
14 17 4.6e-06 0.0004 21.8 1.8 1 23 512 534 512 534 0.98
15 17 0.0024 0.21 13.2 0.3 1 20 540 559 540 562 0.93
16 17 4.6e-05 0.004 18.6 1.4 2 23 569 590 568 590 0.96
17 17 4.2e-06 0.00036 21.9 1.4 1 23 596 619 596 619 0.97

Sequence Information

Coding Sequence
ATGTTCGAACAACAAATCAAGGCTGAGCCTATGAGCTTCTACAATCACCCTCACCTACACACCGGCCCCCCTACGATATCGCGTTCCGAGGGAATATTGCATCACCACCAGGAAGACTCGAAAGACAGCCTTATAGCACAGCATCAGCAGCATCAACAGCTCCTGGACCATGACCCGCAAGATCTGCAGACACACGACCAAGATGAGTTGAGCTTCAAAGGAATGGATGATGAAGGGGTGGAATTGGACATGGATTCAAGACAATGCAATCAGGGATTGGTTGATATGGGCTCAGTACAAACAAAAATTGAAGTTACAAATGGGGGACCACAAACACCCCGATCTAAACCACAAGCTTGCAAGGTCTGTGGCAAAGTGCTCTCTTCTGCTTCCTCATACTACGTCCACATGAAACTACATTCTGGCAATAAACCATTTCAGTGTACGGTATGCGACgcggcgttttgtcgcaaaccgtacctagaagtgcatatgcgcacgcacacgggcgagcggcccttccagtgcgatttgtgctttaagcgcttcactcagaaatccagccttaacacccataaacgagtccacaccgATGAGCACTCCCGCGCGCTCGAGGCCAAGGACAGACCCTTCCAGTGCCATCTCTGTCAGATGCGCTTCACGCAGAGCTCCAGCCTCAACCGACACAAGAAAATACACACGGAGGAGCACAGACGGGCCCTGTTAGAGAAAGTgcggccgtaccagtgctgcgtctgttatatgcgcttcactcagaagtccagcctcggcCGCCACGGAAAGATCCATACCGaggagcacatccgctcgctgatcaacaaagtgcgtccctatcagtgcgacatctgcgacaagcggttcacgcagaagtccagtctcggcactcataaacgtatacacaccggggagaggccgttccagtgcatcgtctgcctcaagtccttcacgcagaagtgcgcgctcaatttgcacgaaaagatacatacgggcgagcggccgtaccggtgcgacgcctgcctcaagcggttcactcagcggtccagtctgaccgcgcacgagcggacacacgcagTCCagggcaggccgttccagtgcctgtcgtgtccggccgccttcacgtgcaagcagtacctggagatccacacgcgcacgcacaccggcgagcggccctaccagtgcgacatctgccacaagcggttcacgcagaagtccagcctcaacattcacaagcggacgcactcagTTCAGGGTcgtccgttccaatgcctgcaatgcccggcggcattcacatgcaagcaatacttggagattcacaaccgcacgcatacaggggagcggccctaccagtgtgaagtgtgccttaagagattcgcgcaaaaatctacccttaacatacataagaggacgcacacggTCCAAGGCAggccgttccagtgttcggaatgccccgcggccttcacgtgcaagccgtacctggagatacactcgcgcacgcacacgggcgagcggcccttccagtgcgacgtgtgtctcaagagattcacgcagaagtccactctcaacatacacaagcgtatacataccgGTGAACGCCCATATGCTTGTGATATATGTCAAAAAAGATTTGCAGTGAAAAGCTACGTTACAGCTCATAGATGGTCGCACGTGGCAGACAAACCTCTGAACTGTGACCGATGCTCCATGACGTTCACTTCCAAATCACAGTTCGCGCTGCACATCCGCACTCACTCTGCGGCTTCCTGCTACGAGTGTAGCGTGTGTGGACGCACCTTTGTCAGGGACAGCTATCTCATTCGGCACCACAATCGTGTGCACCGAAGCGAGAACCACAGCAACATGTCTGCGGCCAGCATGCCGGTCTCTGCCGCCCCCTACGACTCGCCCGGGGTCTGTGATCTCAGTTTCGTGCCGATGGTGAACCGGTACATGACATCTCAAGGCACCCAGGTGTCCATGCAGGACTCCAACAAACTGTCCGCCATGTCGCCCCAGTCCATCGTCTCTATATCGTCGCCGCCGCCGCCGCCCACGCCGCAGCCTCCCATGTCGCACACGCCGCTGCATCTCACCGACTGA
Protein Sequence
MFEQQIKAEPMSFYNHPHLHTGPPTISRSEGILHHHQEDSKDSLIAQHQQHQQLLDHDPQDLQTHDQDELSFKGMDDEGVELDMDSRQCNQGLVDMGSVQTKIEVTNGGPQTPRSKPQACKVCGKVLSSASSYYVHMKLHSGNKPFQCTVCDAAFCRKPYLEVHMRTHTGERPFQCDLCFKRFTQKSSLNTHKRVHTDEHSRALEAKDRPFQCHLCQMRFTQSSSLNRHKKIHTEEHRRALLEKVRPYQCCVCYMRFTQKSSLGRHGKIHTEEHIRSLINKVRPYQCDICDKRFTQKSSLGTHKRIHTGERPFQCIVCLKSFTQKCALNLHEKIHTGERPYRCDACLKRFTQRSSLTAHERTHAVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICHKRFTQKSSLNIHKRTHSVQGRPFQCLQCPAAFTCKQYLEIHNRTHTGERPYQCEVCLKRFAQKSTLNIHKRTHTVQGRPFQCSECPAAFTCKPYLEIHSRTHTGERPFQCDVCLKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCDRCSMTFTSKSQFALHIRTHSAASCYECSVCGRTFVRDSYLIRHHNRVHRSENHSNMSAASMPVSAAPYDSPGVCDLSFVPMVNRYMTSQGTQVSMQDSNKLSAMSPQSIVSISSPPPPPTPQPPMSHTPLHLTD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01452554;
90% Identity
-
80% Identity
-