Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 9.4e-05 1.2 10.8 0.0 26 46 104 124 96 131 0.83

2 6 0.00039 5.1 8.8 0.0 27 47 136 156 132 162 0.91

3 6 0.0015 19 6.9 0.0 26 45 166 185 157 191 0.86

4 6 0.006 78 5.0 0.0 26 45 197 216 187 224 0.82

5 6 0.0067 87 4.8 0.1 26 44 228 246 219 254 0.78

6 6 1.6 2.1e+04 -2.8 0.1 27 43 260 276 257 280 0.77

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	9.4e-05	1.2	10.8	0.0	26	46	104	124	96	131	0.83
2	6	0.00039	5.1	8.8	0.0	27	47	136	156	132	162	0.91
3	6	0.0015	19	6.9	0.0	26	45	166	185	157	191	0.86
4	6	0.006	78	5.0	0.0	26	45	197	216	187	224	0.82
5	6	0.0067	87	4.8	0.1	26	44	228	246	219	254	0.78
6	6	1.6	2.1e+04	-2.8	0.1	27	43	260	276	257	280	0.77

Coding Sequence: ATGGTAAACAATATATGTGGCACAGCTTCTAGTACTGGGCATTGTAAGCTCTCAGTAGTTCCCAACATTAAAACCGAGATTCAAATTAAAGCTGAACCAAGTGCACAAGAAGATGATTTGAGTGAAACTGGGTCTGTTGTAGTAAaatctgaatatgaaaatatgCTAATTAAAAACGAATCTATTGATATAAAACCAGAAAGTGATATAACTGACTCTAAATTGGGACTCGAAGGTGATCAAATGCAAAAATCCACTCTAAAGATCCACCAGTTAGTCCACAAAGAAGTTTCAGGAGTGCCAATGTACACATGTGACATGTGCGAGTATGCAGCCAAGGACAAGCGCAACCTTAAGCGCCACTTGTTAGTTCATAAAGATGCTCCAGAAGTGACAATGTACAAATGCGACATCTGCGACTATGTAGCCAAGCAAAAAGGCACCCTTAAGCGTCACCTGTTACTTCACAAAGATACTTCAGAAGTGATAGTGTACAAATGCGACATGTGCGACTATGCAGCCAAGCAAAAAGACAACCTTAAGCGTCACCTATTAGTTCACAGAGATGCTTCAGAAGTGACCGTGTACAAATGCAGCATCTGTGACTATGCAGCCAAGCAAAAAGGCAACCTTAAGCTTCACCTGTTAGTTCACACAGATGCTTCAGAAGTGACAGTGTACAAATGCGACGTCTGTGACTATGCAGCGAAGCGAAAAGGCAACCTTAAGCGTCACTTGTTACATCACAAAGATGCTTCAGAAGTTACAGTGTATAAATGCGACGTCTGCAACTATGCAGCCAAGTGGAAGTACCAACTTAAACGCCACCAGTTTGTCCACAAAGACGCTTCAGAACTAAAAATGTACAAATGGAACAGGTGA
Protein Sequence: MVNNICGTASSTGHCKLSVVPNIKTEIQIKAEPSAQEDDLSETGSVVVKSEYENMLIKNESIDIKPESDITDSKLGLEGDQMQKSTLKIHQLVHKEVSGVPMYTCDMCEYAAKDKRNLKRHLLVHKDAPEVTMYKCDICDYVAKQKGTLKRHLLLHKDTSEVIVYKCDMCDYAAKQKDNLKRHLLVHRDASEVTVYKCSICDYAAKQKGNLKLHLLVHTDASEVTVYKCDVCDYAAKRKGNLKRHLLHHKDASEVTVYKCDVCNYAAKWKYQLKRHQFVHKDASELKMYKWNR

Sequence clustering based on sequence similarity using MMseqs2