Mtil017352.1
Basic Information
- Insect
- Mimas tiliae
- Gene Symbol
- -
- Assembly
- GCA_905332985.1
- Location
- HG995252.1:13649464-13664279[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00037 0.025 15.4 3.6 1 23 237 259 237 259 0.98 2 10 0.00028 0.019 15.8 6.5 1 23 265 287 265 287 0.96 3 10 0.0019 0.13 13.2 6.9 1 23 293 315 293 315 0.98 4 10 0.00056 0.039 14.8 1.3 1 23 321 343 321 343 0.96 5 10 7.1e-06 0.00049 20.8 1.0 1 23 349 371 349 371 0.97 6 10 1.1e-05 0.00074 20.2 0.1 1 23 377 399 377 399 0.98 7 10 5.2e-05 0.0036 18.1 0.2 2 23 405 426 405 426 0.97 8 10 1.1e-05 0.00077 20.2 0.5 1 23 497 519 497 519 0.97 9 10 7.9e-05 0.0054 17.5 1.4 1 23 588 610 588 610 0.96 10 10 3.2e-05 0.0022 18.7 4.3 1 23 620 642 620 642 0.97
Sequence Information
- Coding Sequence
- ATGTGTATGCCTACACCTAACAATGTCCCGGGTTTTGGATACTCGTGGTTTACGAGTACAGCGGATCTTACCAAAGGTGAAGTGGAGACGCCGAGTAGTCTCAGTTACACCCTGGGCAACACGGTTCCTGAAACGACACTGACTGTTATGTCACACAAAACACCACAGGTGCAAGAGAAAGTTGGTGCTGTCGCCGTAGCAGTATCAAATGCAGGAGTACAGGTTACGAGGGTAGTGACGACAGGAACTCCTGTCACAGCCAGGAGAGCCATGTTCGTGCTAAATGAAGCGCCGGCGCATATAAACAGGGTGTCGCAGCAGAACCAAACGGCCACAATACACACAAACTTAACAGGCAAACCGTTCATGACACCACTCGGACCACTTCAACTAACTCCAGAAGAATGCAATGAGATCCTTATGAAAAGAGCTTTACAAGCTCAAGGCATAGCCACTCCAGTCATAGACACGTCACAACTCAACCATACGTTACTTAATGGTGGTTTGAAGTCCTTGGAGGAAGCAGCCAATCAGCAAGCTCAGGCAGACACTATACAAACAACAACCGTACAACATCATCTCCTGCATACGAAACAGGAGCCTGGGACAGCCAATAGTTCACCTAAAGCAGTCTATTCACAAACGGAGATGATGAACACTAACTCGGTGATGACGACAGTGCCGCCCTCAATAGTGAAGGAGCGGCGTTACTCGTGCGACGAATGCGGCAAGACGTTCTTGCTCAAACATCACCTCACTACGCATGCGAGGGTACATACAGGTGAACGTCCCCATGTTTGCGCCCATTGTGGTAAGGCGTTCGCGAGGAAACACTGCCTGAACACACATTTGTTATTGCATTCTGCGGAGAGGCCGTATAGATGTCACGAGTGCAAAATGGCTTTCACACTGAAGCATCACCTCGTGACACACTCCAGGGTTCACAGTCGAGACCGTCCGTTTGTATGCACTGAGTGCGGTCGGGGCTTCGCGTTGAACCGTCACCTGGTGACACACAGCAAGTACCACGCTGGCGAGAGGCCCTACGTGTGCACCGACTGTGGGGAGAGCTTCGCACAAAAGGAACACCTGGTGATGCACAGCAGGTTCCACGGTTCGCCATCGCCATATGTGTGCAGTGATTGCGGTGCAGCGTTCGCGCGCAAGTTCCAGCTGGTGAACCACGGGCGCGTGCACGGCCGCGTGCCGCCCTCCTGCCCCGTCTGCGGCAAGGAGTTCCTGCAGAAGCGCACGCTCATCGCACATATCAAGACGCACACAGGCGAGAGTGCCGAGGCTTGTATAGAGTGTGATGATTTCAAACCACAGATTGTTCAGACACAACAACAACAAAGGCAAGTCCAACAACAACAGAGACAAGTACAACAGCAGCAAACAATAGTCATAGAGCAGGACGACTTCAAACCGCAAATTGTACAGGTAATGGGTGGAGACGGACAGATAGTGTCAGAAAAGACTACTCCAGGCTATGCATGCCCAGAGTGCGGTTCATGTTTCAACACTAAGGAAGCGTTGACACTGCACGTGCGTCTACACGCAGGCGATCGCACCACTGTGACGGATCTGTGCGCTCTGACCGCCGCGCTGCAGCCCGGACTCGTCGCGCATCACAACAGTAATTATACTACACTATACAAACAACATCAACCTATACAAATTATATCGTCAAATCCCAACAATGTTGTGCACACGCAAGTCATAGCCACGAATCATCACGTAACTCCACCTCGGCCGAAGATACACTTTTGTGGAGACTGCGGCAAAGGTTTCGCGGCTAAACATGGTTTATTAGCACATCAGAGAAGACACCCAGACGGTAGTTGTACATTACGGACGCATGTATGCGATCAGTGCGGGAAAGCTTTCTTCCAGAAGAACCATCTCATGCTGCATCAGAGACAACATATGGACCTGCCGCCTAGAACGAGTCAAGCGCAAGTGAATGCGCAAGCGCAAGCGCAACAAGAGGCGCAACAGGCGGCGCAACAAGCCGCGCAACAGGATCATCAGCAACCCACACATATACAAGTGGTGACAAACAGGTCAGGTCAGGTGATCGGCAATCAGATAGTAGTTGGTGCAGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCGGACGCAGGCTCGTGAGCGCTCCACACGTTATACTGGGACGCGATCACAAGTCACTCGCACAACTTAAACATCACGCCAGGCATCATACCACCAGCGGTGACGTGAAGGAAGTGGGCGGGCTGGTCCTGTCAGCAGGGAGAGGGACGGGGCTCATCAAGTATGAGATCGCTCTCCCTCCTCCTACATCAGTTGTTCAAGTACAACAACTCGACTGA
- Protein Sequence
- MCMPTPNNVPGFGYSWFTSTADLTKGEVETPSSLSYTLGNTVPETTLTVMSHKTPQVQEKVGAVAVAVSNAGVQVTRVVTTGTPVTARRAMFVLNEAPAHINRVSQQNQTATIHTNLTGKPFMTPLGPLQLTPEECNEILMKRALQAQGIATPVIDTSQLNHTLLNGGLKSLEEAANQQAQADTIQTTTVQHHLLHTKQEPGTANSSPKAVYSQTEMMNTNSVMTTVPPSIVKERRYSCDECGKTFLLKHHLTTHARVHTGERPHVCAHCGKAFARKHCLNTHLLLHSAERPYRCHECKMAFTLKHHLVTHSRVHSRDRPFVCTECGRGFALNRHLVTHSKYHAGERPYVCTDCGESFAQKEHLVMHSRFHGSPSPYVCSDCGAAFARKFQLVNHGRVHGRVPPSCPVCGKEFLQKRTLIAHIKTHTGESAEACIECDDFKPQIVQTQQQQRQVQQQQRQVQQQQTIVIEQDDFKPQIVQVMGGDGQIVSEKTTPGYACPECGSCFNTKEALTLHVRLHAGDRTTVTDLCALTAALQPGLVAHHNSNYTTLYKQHQPIQIISSNPNNVVHTQVIATNHHVTPPRPKIHFCGDCGKGFAAKHGLLAHQRRHPDGSCTLRTHVCDQCGKAFFQKNHLMLHQRQHMDLPPRTSQAQVNAQAQAQQEAQQAAQQAAQQDHQQPTHIQVVTNRSGQVIGNQIVVGAVXXXXXXXXXXXXGRRLVSAPHVILGRDHKSLAQLKHHARHHTTSGDVKEVGGLVLSAGRGTGLIKYEIALPPPTSVVQVQQLD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00018396;
- 90% Identity
- -
- 80% Identity
- -