Mtil009973.1
Basic Information
- Insect
- Mimas tiliae
- Gene Symbol
- bab2
- Assembly
- GCA_905332985.1
- Location
- HG995255.1:3030902-3032721[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 8e-25 2.7e-22 79.4 0.1 6 101 30 121 25 130 0.90
Sequence Information
- Coding Sequence
- ATGCAGGGGCTGGTGAGCGACAAAACGTTCCACCTCAAGTGGAACAACCACCTGCAGAACCTGAGCCAGCTGTTCACCACCATCTACTCGTCGTCTGCGCTGGCGGATGTCACGCTCTCCTGCCGCGATGGGACTCTCAAGGCGCACAAGCTCGTGCTCTCCGCCTGCAGCCCTTACTTCGAGCAAATATTCAAAGACAACCCATGTCAACACCCCATCGTGATCCTGAAAGGAATACCATTCTCAGAGATCAATCTGCTTGTGGAGTTTATGTACAAGGGATCGGTGGATGTGCAAGAGCTGGACTTGCAGTCTCTAATGCACACAGCATCAGAGTTGGAGATCCGGGGGCTGGCGTATGAGGCCCGGGACAATGCTGCACAGATGTTGAATGTGAACTTGGAGTACCCATCATATCCTCAGACTTCAGTCCAGGCTGCACAGTCATCATTCACACAATCACGGACCTCAACCACAGATGTTGAGAGGTTAAAACAGGTGGTGCCTATCCAGTCAGCTAAAAAATATGTTAAGTTCCTACCAGTGTACAATCATTCAGTGCCAATTATGAAAGTGGACAAGTAG
- Protein Sequence
- MQGLVSDKTFHLKWNNHLQNLSQLFTTIYSSSALADVTLSCRDGTLKAHKLVLSACSPYFEQIFKDNPCQHPIVILKGIPFSEINLLVEFMYKGSVDVQELDLQSLMHTASELEIRGLAYEARDNAAQMLNVNLEYPSYPQTSVQAAQSSFTQSRTSTTDVERLKQVVPIQSAKKYVKFLPVYNHSVPIMKVDK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00356437; iTF_00341470; iTF_00791339; iTF_00448276; iTF_00290838; iTF_00787813; iTF_01359002; iTF_00432379; iTF_00163109; iTF_01402821; iTF_00922986; iTF_00710348; iTF_01173420; iTF_00063737; iTF_00321721; iTF_00662361; iTF_00786937; iTF_00178362; iTF_00704154; iTF_01359898; iTF_00250619; iTF_00013213; iTF_00125245; iTF_00711135; iTF_00948031; iTF_01403583; iTF_00781954; iTF_01017859; iTF_00205317; iTF_01508200; iTF_00776809; iTF_00778857; iTF_00986378; iTF_01078350; iTF_00257071; iTF_00256080; iTF_01080852; iTF_00781145; iTF_00824891; iTF_01021436; iTF_01080028; iTF_01092191; iTF_00811174; iTF_01452490; iTF_01153133; iTF_00025343; iTF_00144782; iTF_00687983; iTF_00164513; iTF_00934956; iTF_01248333; iTF_01178768; iTF_00744883; iTF_00403958; iTF_00406038; iTF_00933976; iTF_01217629; iTF_01561242; iTF_00802045; iTF_00354304; iTF_00353284;
- 90% Identity
- iTF_00187297; iTF_00112625; iTF_01317435; iTF_00787813; iTF_00448276; iTF_00063737; iTF_00341470;
- 80% Identity
- -