Mtil001271.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mimas tiliae
Gene Symbol
ibtk
Assembly
GCA_905332985.1
Location
HG995256.1:10738815-10754545[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 9e-15 3e-12 47.1 0.0 6 79 539 611 534 626 0.90
2 3 1.4e-10 4.5e-08 33.6 0.0 9 107 735 837 729 840 0.83
3 3 2.4 7.9e+02 0.7 0.2 79 107 841 869 837 872 0.87

Sequence Information

Coding Sequence
ATGAGTAAACATAAAGTGGAAGTGGACTGCACAAGCCGGTGCAAGTCACGGACGCATGGACAAGTACTCACAAGTGCCATTACAAAGAGATCTTTGACTGATGAAGCTCTCGCCAGCTTTATCAAGGCGACATGTGCTAATTTCATCAAGGCTTTTGACAATGAGGGTCGCACAGCGTTGCATATGGCGGCATCTCGCGGCCGGGTAGCATTAATGGAATGGTTGATACGTCACTCTTCTGATGCATTCATAAACGCTCGAGATCGTGAATCTGGCTACACACCATTACACAGAAGCATATTCTATGGCCAAATACATGCTGCAGTGTCATTGATGAAAATAGGTGTCAGCATAGACATTGTAGACAAGGATGACTATAAAGCGCTGGATCACGCGATGTTAGACCGCCACTACATGTACAAACATGAAGGCACACAGCCGAGCGAGGTGTACGTGTGGGGCAGCAACTCTAACTACACGCTGGGCACCGGCACACAGCAGCAACGAAACGCGCCCGAGCTGTTGACTTGCTTCAGTCGCACCAACACTTGTGTCAAACAGGTGTGCCTAGGTAAGTTCCACAGCGTGTGGGTGACGTCAGGCGCCGGTGGTGACGAGGTGTGGTGCTGTGGCCAGTGCGGGCGGGCCGGTGGTCCTCACACTACAGCGCTAAGGCCTGCGCCCCTTCGTCTCCCCGAGCCTTGTGTCTGTGCAGCCATTACGCTTACTTCTACTGTGGTGCTACTTGAGAGTGGAGCGTCGACTACCAAAACCCCATCACTAATACGTCCGCATTCAACCAAGCCACTTATAAAACTATCATCCCCACTGGGAGTGCGAGCGGCTCGGTCTCACGCCGTTGTATGGAACACGCGCGCCATCTATACGTGGGGGACTAATGTGGGACAATTGGGACACACGCAGGAGGATAAACACGTGCCCGCGCCTAAACGGGTGGCAATACATGTGAACAACAAAGAGGAGGCCGGATTAGAACTGGTGGATGCAGCGGACGCGGCCACCGTCATCACCACAAGCCGTGGGGATGTTTATCTACTGCACAAGTATATTTGCAAGAAGATTGCTATCAAACAAATAAATCTGCGTCAAGTATGCGTGGAGGCAAAAGTGAGCGAGCAAGGCGCTTACTCACGTGTTACAGTACTACTGCTCACTAATGTCGGACAAGTACTCATATGGCAGGACACCACTAACAAACTTACCAGATGCGTTTTTGGTCTACAACACCAGACATTCATAACTCACATACAATTAACCCACGATGCTCTTTACTGCACGACGAAACACGGCGAAGCGTACATTGGTTCGATCTCGCGCAAGACCACGCCCACATCCCAGCCGCAGCCAATCAGGAAGGAGAGAGACAAGGACATAAAGAGTCCACTTGTTAAGTTCTTAGAGAAGGACGACTGCACTTCTGTCAGGATCATGAGAATACCCAATATTTATAGGGCTGTTGCTATCGCCGTTGACGGTGAAGGGATCAACTTCGCGTGTTTGCAGATAAAACCCACTTGTGGATTGCGGTCATTGCCTGAACTGTCTCCTTCGAGCTTGTCCAAACATATGGAGTCGTTGAGGGAAACTGCAGCCGAAGAAGATATACTCCATGATGTTATATTTAAGGTCGGCACAAAACACTTCCCAGCGCACATGTACATAGTTGGCGCAAGTAGCGAACACCTATACAAATTGTACCAAGAAAAACTGAATATTCAAGGTCCCAAACCAATAGTAGCACTTGAAAATGTTCACCCAGAGGTGTTTGAAAGGTTATTAAAGTACATGTACACTGGTACTTGTGATGTGGCAGAGTTGGGACCGTGTGGCCTCAAGATAAGGAAGGAAGATCTGATTGCCACAGGGAAGAAAGACACTGAGAGTGTTGAGGTTGAAATGGAATTGATTGAAAATCCACTAGAGGTGTCAGCGTTTGAAGTGTACAAAAACGAGAAGAATAAGCGTGGCGGTAGAAATCGTCGCAATACAGACACTCCACCGCGAATCAACCTCTACTGTGATCCAGTGAAGTTGGTCCAAGCCGCCGCCAAGAGACTGCAGATCATGGCTCTACACAAACTGCTGGATAAGTTCTATTACAGAGATGGAACGGTGTATTTGAAAGAGAGTGCGACGTTTAGTAAAAACTTGCCAATATATTGGAACCGTGAACAGTTCCCCGAGCTGGTGGATACCAACGTTTGTTCGAAGGATGGAATGCTCATATCAGCACACAAGTGCATTCTGGCTGCCCGCTTGGAATACTTTAACGGGATGTTTATGCATTCATGGACTGAGAGCAAATTATTATCAAAAGTAACGCTCCCAATCAACCATGGCATTCTACTGCCAGTTATTAATTTCCTCTACACAGACTCATGTCCAGAAATAGACAACTGCGACAGTATCGACTTTGTATGCAACTTGTTAATAGTCGCCGATCAGTTGTTCATATCCCGGCTGAGGGAAATGTGTGAAATCGCCTTAGCCAACTTGATAACACTTAAAAATTGCACAGAACTATGCCAATTTGCACATACATACAACGCCACGCAACTCAAACAATGTTGTATGGAGTTTATCTCGCTCAATCTATGCAGTGTACTTGAAAATAGGTCACTAGACTTAGTGGAAGATACCTTACTCGATGATATTACTAATTACTATTGTAAATTCAACCCAATAATGTCTTCGAGGGTTATTACACCCTTCTATAACGCTCCCAGCGATGACGTCATAGACGAATTAGCTAAAATGTACCCTCTAGACATGAACTACACAGATGAAGATTGTAAGAAAGATGACAGCATATCGGATTCCACTAAAAAAAAGACTAAACAATCTAAGAAAATTGAGTATACCGACAGAGAGAAAGAAAGGATGCGGTACGAATCTGTAAGCTCTGTGACGTCACTTGACATGTCAAATGATACTGGTGACATAACTTTGTCATTGAGCAAGATTGGGAAGGAAGAAAAGGGGGCGCGCGACAAACAAGAGAAATGGATCGAAGTGCCGTCAGCCCAACAGAAACAAGCTAAAGTAGTACAAGCGAGATTAAAAGCTATTAGCAGTGCGAGAGATATTTTAAATGAAACTCCGACTGAATCTTTTGTTAAGCTTAATAGGAGTGGATCTTCAAGTGCCATGACAGAACCCACGACTTCTCGAATGTCTGTGTCTCCAAAAGACTCGCCTGTAGCCGAAATGGCCAGGAGCCCACAAGGAAATTTTATTATCAGTCACATTGGGCCCAAATTATCACAAAAGCAAAGGAAAAAGTTGGCCATGCAAAGCAGCGATCAGTCAACAAATTTGGATGAGTACATATCTAACAAGCTGACCTTGGACAGTCCACCAGAAAAACCTAAAAATCCATGGAAAATTTGCGAAACACCTGTAGCAAGCCGCAGCCCCAATACTAAACCAGTTGAGTTCAATAAAATTTTAACTGATCAAAGGAAACAGAAGGAGGATTTCTCAAGAATTATGACAAAGCCATTGATATTAACTCAGCTGGAAGATAAAGCCATAGAACAACTGGAGAAGTTCTACAACGCCCGTGAGATTGATGATGAGTTGATAACGGTCCATCGCATAGAGCTTCAAGTGTCTTCCCCGCAATGGATACACACTGCCCCAAAGTGA
Protein Sequence
MSKHKVEVDCTSRCKSRTHGQVLTSAITKRSLTDEALASFIKATCANFIKAFDNEGRTALHMAASRGRVALMEWLIRHSSDAFINARDRESGYTPLHRSIFYGQIHAAVSLMKIGVSIDIVDKDDYKALDHAMLDRHYMYKHEGTQPSEVYVWGSNSNYTLGTGTQQQRNAPELLTCFSRTNTCVKQVCLGKFHSVWVTSGAGGDEVWCCGQCGRAGGPHTTALRPAPLRLPEPCVCAAITLTSTVVLLESGASTTKTPSLIRPHSTKPLIKLSSPLGVRAARSHAVVWNTRAIYTWGTNVGQLGHTQEDKHVPAPKRVAIHVNNKEEAGLELVDAADAATVITTSRGDVYLLHKYICKKIAIKQINLRQVCVEAKVSEQGAYSRVTVLLLTNVGQVLIWQDTTNKLTRCVFGLQHQTFITHIQLTHDALYCTTKHGEAYIGSISRKTTPTSQPQPIRKERDKDIKSPLVKFLEKDDCTSVRIMRIPNIYRAVAIAVDGEGINFACLQIKPTCGLRSLPELSPSSLSKHMESLRETAAEEDILHDVIFKVGTKHFPAHMYIVGASSEHLYKLYQEKLNIQGPKPIVALENVHPEVFERLLKYMYTGTCDVAELGPCGLKIRKEDLIATGKKDTESVEVEMELIENPLEVSAFEVYKNEKNKRGGRNRRNTDTPPRINLYCDPVKLVQAAAKRLQIMALHKLLDKFYYRDGTVYLKESATFSKNLPIYWNREQFPELVDTNVCSKDGMLISAHKCILAARLEYFNGMFMHSWTESKLLSKVTLPINHGILLPVINFLYTDSCPEIDNCDSIDFVCNLLIVADQLFISRLREMCEIALANLITLKNCTELCQFAHTYNATQLKQCCMEFISLNLCSVLENRSLDLVEDTLLDDITNYYCKFNPIMSSRVITPFYNAPSDDVIDELAKMYPLDMNYTDEDCKKDDSISDSTKKKTKQSKKIEYTDREKERMRYESVSSVTSLDMSNDTGDITLSLSKIGKEEKGARDKQEKWIEVPSAQQKQAKVVQARLKAISSARDILNETPTESFVKLNRSGSSSAMTEPTTSRMSVSPKDSPVAEMARSPQGNFIISHIGPKLSQKQRKKLAMQSSDQSTNLDEYISNKLTLDSPPEKPKNPWKICETPVASRSPNTKPVEFNKILTDQRKQKEDFSRIMTKPLILTQLEDKAIEQLEKFYNAREIDDELITVHRIELQVSSPQWIHTAPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00859625; iTF_01358986; iTF_01430061; iTF_00819308; iTF_00429166; iTF_00428276; iTF_00820223; iTF_01312336; iTF_00112630; iTF_00112627; iTF_00113432; iTF_00858706; iTF_00290841; iTF_00063738; iTF_00341463;
90% Identity
iTF_00063738;
80% Identity
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