Mtil019993.1
Basic Information
- Insect
- Mimas tiliae
- Gene Symbol
- Rfx2_1
- Assembly
- GCA_905332985.1
- Location
- HG995238.1:23349888-23358538[+]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 6.4e-32 7.5e-28 97.3 0.6 16 78 4 66 1 67 0.96 2 2 0.6 7.1e+03 -1.9 0.0 24 33 445 454 428 463 0.68
Sequence Information
- Coding Sequence
- ATGGTGCGTGCAGGTGTATCGCTGCCGCGCTCGACGCTGTACTCGCACTACCTGCGTCACTGCGCGACGCACCGCCTGGAGCCGGTGAACGCCGCGTCGTTCGGCAAGCTCATACGCTCGGTGTTCGTGGGCCTGCGCACGCGCCGCCTCGGCACGCGCGGCAACTCCAAGTATCACTACTACGGGATACGCGCCAAGCCTAGTGCCAACAACGCGGACATACACCACGATGCGCATGATGATAAGACTGACGTGCTTGATGCGCAGGAGGGTCGCTCCCGTTCGAGCGAGCGCGACGCCGCGTCCAGCCCGGCCAGCAGCGGCGGCGGGACCGGACACGCGTACCGACAGTACCTGGGACCCGTCGCACCGCCGGACCCACCCGACCTGGTGCTGCACGACCTGCCGCCCGACGTGCCGCCCGCCGCACTGCACGCGCTGCGACGACATCACCGAGAGCACGGCGCGTCGTTCCTGGAGGCGGTGAGCGCGCTGGACACGGCGGGCGTGGAGCGCGCGCGTCGTGCGTTCTGGCGCGGGTGTAGTGCGGGCGCGGGCGCGGGTGCGGGTGCGGGCGTGCTGTGTCGCCGCGTGCTGTGCAAGCTGGCGGCGCGGCGCGACGTGGCGCGCTGGCTGCGTGCGGCGGACCTGCAGCTGCACCAGCGCGCCGTCGACCTGCTGCTGCCTGATGTGCTGCGACCCATCCCGCCGCAACTCACGCAGGCGATCCGCAACTTCGCTAAGAGTGTAGAGGCGGCTGTATGTGGCGGCGCGGGCAGTAGTGGTGGCAGCGTGGGCGTGCCGTCAGCTAGCGCGCGCGCTCAAGCCGCCGCGGCGGGCGCGCTAGCCGCCGCGCTCAGGCGATACACGTCACTCAACCATCTAGCGCAGGCTGCACGAGCTGTGCTCACCAACCATCATCAGATACATCAGATGTTGGCGGATCTGAACCGCGTGGACTTCAGAGTGGTTCGCGAACAAGCCGCGTGGGCGTGCTCGTGTGGCAGCTCTACTACTGCGCAACGACTTGAGGCTGACTTTAAGGCAACACTGGGTCGCGGTGCGTCACTAGAGCAGTGGGCGGGGTGGCTCGACGCGTGCGTGCGCACCGCACTAGCGCCGCACGAGCGGACACCGACCGCCACCGGTGACCCACCCGACCGTACCGACCATACCGACCACGACCACGACCATCCCGACCATCCCGACCACACCGGCTACACGGCACGCGCGCGCCGTCTGCTGCTCGACTGGTCCTTCTACTCCTCGCTCGTCATACGCGAGCTCACGCTAAGGTCGGCGGCGTCGTTCGGTTCATTCCACCTGATCCGTCTGCTGTACGACGAGTACGTGTCGTACCTGATCGAGCGCCGCGTCGCCGCGCACAACCGAGTGCCGCCCATCGCTGTCATGCATCGCGTACTGGAGGAAGAGGAGGAGGTTTCTGAAGACAACATGCGCGCCGACATCGAGGAGGAAGACGGCGAGTGGGACTGGGAGGACGACGAGGACGACGACGACGATCTTCCTGACTGCAAGAAGGTCAAGATGCACTGCGAGTGA
- Protein Sequence
- MVRAGVSLPRSTLYSHYLRHCATHRLEPVNAASFGKLIRSVFVGLRTRRLGTRGNSKYHYYGIRAKPSANNADIHHDAHDDKTDVLDAQEGRSRSSERDAASSPASSGGGTGHAYRQYLGPVAPPDPPDLVLHDLPPDVPPAALHALRRHHREHGASFLEAVSALDTAGVERARRAFWRGCSAGAGAGAGAGVLCRRVLCKLAARRDVARWLRAADLQLHQRAVDLLLPDVLRPIPPQLTQAIRNFAKSVEAAVCGGAGSSGGSVGVPSASARAQAAAAGALAAALRRYTSLNHLAQAARAVLTNHHQIHQMLADLNRVDFRVVREQAAWACSCGSSTTAQRLEADFKATLGRGASLEQWAGWLDACVRTALAPHERTPTATGDPPDRTDHTDHDHDHPDHPDHTGYTARARRLLLDWSFYSSLVIRELTLRSAASFGSFHLIRLLYDEYVSYLIERRVAAHNRVPPIAVMHRVLEEEEEVSEDNMRADIEEEDGEWDWEDDEDDDDDLPDCKKVKMHCE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -