Basic Information

Insect: Microplitis mediator
Gene Symbol: ZFX
Assembly: GCA_029852145.1
Location: CM056854.1:14307668-14312101[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.4 2e+02 3.7 0.1 3 23 15 35 14 35 0.94

2 15 3.6 5.1e+02 2.4 2.2 1 23 924 947 924 947 0.80

3 15 0.0052 0.75 11.3 0.8 2 23 1034 1056 1033 1056 0.95

4 15 0.0016 0.22 13.0 0.1 2 23 1069 1090 1068 1090 0.97

5 15 1.7e-05 0.0024 19.1 3.1 2 23 1093 1114 1092 1114 0.97

6 15 0.0019 0.28 12.7 0.3 1 23 1120 1142 1120 1142 0.97

7 15 2.8e-05 0.004 18.5 4.5 2 23 1149 1170 1148 1171 0.95

8 15 0.12 18 7.0 3.7 5 23 1184 1202 1183 1202 0.97

9 15 2.5e-05 0.0036 18.6 1.5 3 23 1209 1230 1208 1230 0.97

10 15 0.014 2 10.0 0.5 2 23 1246 1266 1245 1266 0.97

11 15 7.5e-05 0.011 17.1 0.7 1 20 1272 1291 1272 1294 0.92

12 15 9.3e-05 0.013 16.8 2.7 1 23 1302 1324 1302 1324 0.99

13 15 0.0026 0.37 12.3 3.2 1 23 1330 1352 1330 1352 0.97

14 15 4.7e-06 0.00068 20.9 3.9 1 23 1358 1380 1358 1380 0.99

15 15 0.0005 0.072 14.5 6.0 1 23 1386 1408 1386 1409 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.4	2e+02	3.7	0.1	3	23	15	35	14	35	0.94
2	15	3.6	5.1e+02	2.4	2.2	1	23	924	947	924	947	0.80
3	15	0.0052	0.75	11.3	0.8	2	23	1034	1056	1033	1056	0.95
4	15	0.0016	0.22	13.0	0.1	2	23	1069	1090	1068	1090	0.97
5	15	1.7e-05	0.0024	19.1	3.1	2	23	1093	1114	1092	1114	0.97
6	15	0.0019	0.28	12.7	0.3	1	23	1120	1142	1120	1142	0.97
7	15	2.8e-05	0.004	18.5	4.5	2	23	1149	1170	1148	1171	0.95
8	15	0.12	18	7.0	3.7	5	23	1184	1202	1183	1202	0.97
9	15	2.5e-05	0.0036	18.6	1.5	3	23	1209	1230	1208	1230	0.97
10	15	0.014	2	10.0	0.5	2	23	1246	1266	1245	1266	0.97
11	15	7.5e-05	0.011	17.1	0.7	1	20	1272	1291	1272	1294	0.92
12	15	9.3e-05	0.013	16.8	2.7	1	23	1302	1324	1302	1324	0.99
13	15	0.0026	0.37	12.3	3.2	1	23	1330	1352	1330	1352	0.97
14	15	4.7e-06	0.00068	20.9	3.9	1	23	1358	1380	1358	1380	0.99
15	15	0.0005	0.072	14.5	6.0	1	23	1386	1408	1386	1409	0.95

Sequence Information

Coding Sequence: ATGGAACTCGGCGTTACGACAGATACCGGAGGGGCGGTCGCATGCCCTGTATGTACACTCTACCTCAGAGAGGGTATAAGTCTTCAGAGGCACTTGGACACCCATCCAAAGGAACAAGTTATAGAGGCACTGATAAAAGCCAGTGGCTCGTCGTCAAATTTGTCGTCTCTTCAGTTACCTCAAACCCAAGTGCCTCAGGTACCGCAAACCCTTCAGCCGTCACCGCCGCAACAGCAGGTCAATGCCCAAAGCTCAACTTCAGCTCCAACAGCAGCAGCTGTTGCTGCTGCTCACATTCCTACGCAGGCCCCGTTTCCCATTGGACCTGTCTTTGAGTGTCCACCGATCAATGCAATGATGCCACCACAGTTTGCCtcttttaattatcaacaatttGTCAACAATGGTACTATGATGATTCCACAGTACGCGATGGCACCACCTCAGGCAAATCAGATGATGCAAATGCTCTATAATCCATACATGTACCAACAGCAACAGGTACCGACTGTGCAGATGATTTCACCAGTATCAGCACTTCCAACAACCCGTATTAGGCCGGTAGTCACTGTAGCTAACACTGAAACTACCAGAAATGTTATGATATCTACTAGTACTAATGAACCTAAACAAATAATACCTGAGATGATTTCAGAGGCAAATATGGAAAGAATTTTACCAGACATGGACACTTGTACAAATTCAAATCAACAATCGACAGAAAATACAACAGATATACGACACGATGATCATGACGGTGATAATTTGGTTAGACAACTGGATCATCGAGATCAGCAAACCCAGAGTAATTCACCGAGACGAGTGGCAGATAATAGTGAAGTTGTGAGAAATGATGCTGAATCAGCAGTGCCTGAAGAAGAAAAGTCTGAGAGTATTCTTCCGGATATGGAAGAACCAGAAGTTGATAATACTGGTGATCAATGTAGAAATGAACAGCATTTACAACAGGATCAAGAACATCAGACATTTTCATCTACATATAATCAAATTGACAGTGAAAATAGTGGTACAGATACACGACTAAATCAGCATAGACAAGAACAAGATAAATTTGAGACTCAAGAACCGagtaatattgaaaaattaaactcTTCAAAGTCTATTGAGTCACAAATAAATTCAGCTCAAACTCCGATGGTATTAGAAACATGTCAGCAAAATGAAGAAGAACATCTCGAGCATCTTCTTATTACAATGATCGAGTCTGGTTTTGTTGAGACGCATGAGCAAACAAATGTTGTTCATGAACCCAATTCAGAATCTAACCTTAAAACAATTACAACCCAAAATGAAGAACAAatggaagaagaagaagaacaagaagaagaagaagagatagaagaagaagaggaagaagatgatgatggtgaagaacaagaagaagaatcacaaaataattttacaacgATTGACGaaactaaatatattaatgacAGTGAAGCTTGCGTAGAAAGGGAAAAGTGCATTGACACGATTATTATTGACGAATGTGACTTGGACTATGCATATCGGTATAGACATAGTTTATCAGCGCCTGCGTCTCCAGTATCagcgtcaaaaaaaatatcacggCCTTACACAAGATCAGAGTGTGGTTCAactgaaaatcttaatttttatccAGCTGGTTTTGATGCTACTGCACTGCAAgaagaagaagaagaagaggaagaagaagCTAAACGTGTGGGTGATAATTTTGATGAAGAGGATATGGAGATTGAAGAAATAGCTAGTCCACATACACCAttcattaaacaaaatgatgattttgatAATGCACGTTCTCATACGCCATTATCAGCAATCAGTGGTATCTCTGGTCTTCGAGTACGTAGCGATCTTAGTAAACCATCATCACCAGTTTCGATGCGGTCATTTGATCACATGGAAGGTGATAGTCATGATGAAGAAAGCACTGATTCCATAACAAGTCAGAAACATCAAGTTGATTGTTCACAAGTTGATCACAGTGTAGTAAGGTCAAGTCATGATATATCTGAAGGTGCTTGTATTGATGCTGTAAgaaaatcagaaaataataCCAGTGGAATCTTTCATCAGTCTGTTATTACTGAGCATGTTAGCTCATTTCCAGCAATTCATTCGCAACAATCAATaactaatgataattattcaatatctaatagtaaaattataaCGCGTCAATCAGATTTAAGTTGTGGTTTATCCCAAACAATAGAACCTACTACGACAAGTATCGAATCTAAGAGTTTTCAATCAACATTAACTAAAACAGTAAACAACATACCAACGACTGAGCTTCTTAATATCAACGAAGACGCCCATTCAGGTCCTATGAATGTATTCGAATTTGATGGACTTCAAATTCTTGTTCCTAGTACATTTATAAGTGAATCCTCGCAGAAGGCAATCAGTGCAACAAGTCAACAGTCAATGGCAAGCAGTGAAGGAGGTGCAGGTATTGATGAAGAAGTTAAGAGTGTCAACATGCGGGCTGATGAGACGATGCCACCAAGGGGAGAGCTGTCTGAGCAGGAAAGCAACGGCTGCACGGAACACTCGGCTTGGCAGCTATACGTTGGTCAAGAGTCTTCCCGTATGTCGACATCGTATGATCTGATGGCACGTGAAAGCTGGGAAGAGTCAGAGGGATCTGATAATGAGGCCGGTGTACCCCTATTGGATAGTCGTTCACTCGCTACTCACTTTACTTCCAGCTTATTTCTTGATCGAGATAGAAAAACACCAACAAAACAACGTACATTTAAATGTTCACAATGTTCAGAGGTTTTTGATTGCCCGAAAGAACGACGTGTTCACAGTACAACTGTACACAAAGAAGCTGGTCCAAGTAACAGTTGCAGTAACAGTGATATTGCCGAACAATCTGAAACAAAAGATATAAAACTTCTCGATGGTCCCATGAATCcttttgaggatatttttgttCCTGGTATACATGTTCAACAGGCCTATCAACAGCAACAACCGTTGCTACATCAAATGCAACCACCACAACAATTAAGTGACATCAGTAAAGTTGAAACTGATGAAAAAACAGAAAGTCTTGCTTTAACACAGGGCATAGAAATTTCATGTGCCATGTGTACACAACGTTTTAGTTCTGAACGAAGTTTACAGATGCACAATAGACGTGTTCATGGTACCGAAGTTGCACGACGTCTTCATGATATTTCAAAATGTCAAATATGCAATGAAGAATTTCCTTCAGTCGCTTTATTTAATgctcatttaaaaattcatccgCTTGAATGTTCTCAAtgtggtaaatatttttatcgtaaacaaaatttcaaattacataTGAAACGTCATCTTGGTATTAAACCATTTCCATGTACCGTTTGCGATAAAgcatttttaacaaaacaaaaattagatgAACATATGAATGGTCATACGGGTAATGCACCAGTTAAATGCAATCTCTGTAATGAAACATTCCGCAGATACTCAAATTTAACTCAACATAAAAATCGTcatcatttaaatataaaacgtaaattaaaagattataTATGTCACTGTGGTGAAGTatttcatacaaaaaaaaagcttgCTTGGCACAAGGAAACACACGATGAAAAACCTAAAGCATGTACCTATTGCAATGAAAGATTTATACACATGGCTAGTTTAACACGTCATATGCGACGTGCTCATAATCGTCGTTTTGTACCAGATGCTCAAcgtgaaaatgaaaatgttGAATGTCCAATATGTAAGTGCATCTATTTACGTTCATCATTGTCGGTTCATATGCGTGTACACAATGGAGAACGTCCTTATGAGTGTCAGGTGTGTTCGAAAGCATTCAGTACCAAGTGGAACTTACAATTACATAAATGGACTCATGCAGCACGTAGCACCAAACCCTTTAAGTGCAATCAGTGTAGCGCTGCGTTTTATCGTCACAGCGATTATACAGCACACATGAACTCACATAGAAATGTAAGACCGTATACATGTAATTATTGTGGCGCtcaatttataagaaaatacaattgtttaaGACATGTTAAAGAACATGAAGAAAATAAAGCGTACACGTGTGACGTATGCAATAAAACTTTTCACCGGTCATATTATCTAAAAGAGCATTTACGTGTTCACAGTGGTGCACGACCATACGCGTGTCACATATGCGGTAAATCAAGTAGTACCAAGTCAAATCATAATAAGCACGTGAGAATTCATCATGCTCGTGAGCCTGTaaatactgaaaattaa
Protein Sequence: MELGVTTDTGGAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASGSSSNLSSLQLPQTQVPQVPQTLQPSPPQQQVNAQSSTSAPTAAAVAAAHIPTQAPFPIGPVFECPPINAMMPPQFASFNYQQFVNNGTMMIPQYAMAPPQANQMMQMLYNPYMYQQQQVPTVQMISPVSALPTTRIRPVVTVANTETTRNVMISTSTNEPKQIIPEMISEANMERILPDMDTCTNSNQQSTENTTDIRHDDHDGDNLVRQLDHRDQQTQSNSPRRVADNSEVVRNDAESAVPEEEKSESILPDMEEPEVDNTGDQCRNEQHLQQDQEHQTFSSTYNQIDSENSGTDTRLNQHRQEQDKFETQEPSNIEKLNSSKSIESQINSAQTPMVLETCQQNEEEHLEHLLITMIESGFVETHEQTNVVHEPNSESNLKTITTQNEEQMEEEEEQEEEEEIEEEEEEDDDGEEQEEESQNNFTTIDETKYINDSEACVEREKCIDTIIIDECDLDYAYRYRHSLSAPASPVSASKKISRPYTRSECGSTENLNFYPAGFDATALQEEEEEEEEEAKRVGDNFDEEDMEIEEIASPHTPFIKQNDDFDNARSHTPLSAISGISGLRVRSDLSKPSSPVSMRSFDHMEGDSHDEESTDSITSQKHQVDCSQVDHSVVRSSHDISEGACIDAVRKSENNTSGIFHQSVITEHVSSFPAIHSQQSITNDNYSISNSKIITRQSDLSCGLSQTIEPTTTSIESKSFQSTLTKTVNNIPTTELLNINEDAHSGPMNVFEFDGLQILVPSTFISESSQKAISATSQQSMASSEGGAGIDEEVKSVNMRADETMPPRGELSEQESNGCTEHSAWQLYVGQESSRMSTSYDLMARESWEESEGSDNEAGVPLLDSRSLATHFTSSLFLDRDRKTPTKQRTFKCSQCSEVFDCPKERRVHSTTVHKEAGPSNSCSNSDIAEQSETKDIKLLDGPMNPFEDIFVPGIHVQQAYQQQQPLLHQMQPPQQLSDISKVETDEKTESLALTQGIEISCAMCTQRFSSERSLQMHNRRVHGTEVARRLHDISKCQICNEEFPSVALFNAHLKIHPLECSQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHMNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKRKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRENENVECPICKCIYLRSSLSVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYACHICGKSSSTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00379092;
90% Identity: iTF_01004535; iTF_01003738;
80% Identity: -