Mmed008965.2


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Microplitis mediator
Gene Symbol
-
Assembly
GCA_029852145.1
Location
CM056847.1:21712689-21714863[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 7.3e-06 0.0011 20.3 4.2 1 23 10 32 10 32 0.98
2 22 1.8e-06 0.00026 22.2 4.3 1 23 38 60 38 60 0.97
3 22 0.00021 0.03 15.7 2.4 2 23 67 87 66 87 0.97
4 22 2.7e-06 0.00039 21.7 3.8 1 23 93 115 93 115 0.98
5 22 7.1e-06 0.001 20.3 2.1 1 23 124 146 124 146 0.98
6 22 1.8e-06 0.00026 22.2 1.0 2 23 153 174 152 174 0.96
7 22 8.8e-07 0.00013 23.2 2.4 2 23 181 202 180 202 0.95
8 22 5.9e-07 8.5e-05 23.7 1.5 1 23 208 230 208 230 0.97
9 22 6.6e-07 9.4e-05 23.6 3.1 1 23 236 258 236 258 0.97
10 22 0.00044 0.063 14.7 1.5 2 23 265 285 264 285 0.97
11 22 0.00025 0.036 15.5 4.7 1 23 291 313 291 313 0.98
12 22 1.5e-06 0.00021 22.5 1.9 1 23 322 344 322 344 0.98
13 22 1.2e-06 0.00017 22.8 1.2 1 23 350 372 350 372 0.97
14 22 2.3 3.3e+02 3.0 0.1 13 23 378 388 377 388 0.91
15 22 0.0011 0.16 13.4 1.7 2 23 395 415 394 415 0.95
16 22 0.11 15 7.2 0.4 8 21 428 441 421 441 0.86
17 22 4.6e-05 0.0066 17.8 0.6 1 23 472 494 472 494 0.99
18 22 5.1e-06 0.00074 20.8 3.3 1 23 500 523 500 523 0.97
19 22 0.035 5 8.7 2.5 1 23 564 587 564 587 0.97
20 22 0.1 15 7.3 0.4 1 23 593 615 593 615 0.83
21 22 0.00047 0.067 14.6 1.9 1 23 621 643 621 643 0.99
22 22 0.098 14 7.3 0.4 1 23 649 671 649 671 0.93

Sequence Information

Coding Sequence
ATGGGTATTCATACCGGTGAAAATATGCATGAGTGTCATAtttgtctaaaaaaattcaatacagCGAGTAATATGAAGTTACACATGCGTATTCATACTGAAAAAACCTCATATGAGTGTAAAGTTTGTAAAAAGAAATTCACTAGAAAACATTCTCTGAAAAGTCACATGGGTATTCATACTAGTGAAAATAAGTCTAAGTGTGAAATTTGTAAACGACAATTTACCAGATACTATTTAAAAAGTCACATGAAAATTCATACCGGCGAAAATATGCATGAGTGTAAtatttgtcgaaaaaaatttagtacaACGAGTAATATGAAGCTCCACATGCGTATTCATACTGGCACAACCTCATATAAGTCATATAAGTGTGACATTTGTAATAAGAAATTCACTAGTAAACGGTCTCAAATAAATCACATGAGTATTCATACCGTCGAAAATAAGTCGGAGTGTAGAATTTGTAAAAAGAAATTCACTAGAAATGAGAATCTAAAAATTCACATGGTTATTCATACCGGTGAAAATATGTGTGAGTGTgaaatttgtaaaaagaaaTTCACTAGAAAAGAGAATCTAAAAATTCACATGGTTATTCATACCGGTGAAAAGATGTATGAGTGTAAGATTTGTAAAAAGAAATTCACTAGAAAAGATTATCTGGGACGTCACATGGTTATTCACACCGGTGAAAAGATGTATGAGTGTGGCAtttgtaaaaagaaatttactacaaaataTCATCTGAAAAGTCACATGGGTATTCATACtagtgaaaataagtctgaGTGTGAAATTTGTAGACGACAATTTAACAGATACTATTTAAAAAGTCACATGAAAATTCATACCGGCGAAAATATGCATGAGTGTAAtatttgtcgaaaaaaatttagtacaACGAGTAATatgaagttccacatgcgtaTTCATACTGGCACAACCTCATATAAGTCATATAAGTGTGACATTTGTAATAAGAAATTGACTAGAAAAGATTATCTGAAAAGTCACATGGGTACTCATACCGGTGAAAATATGTATGAGTGTGACATTTGTAAAAAGAAATTCACTAAAAACGATTATCTGAAAAGTCACATGGGTATTCATACCGGTGAAAATATAAAAGATAATCTAGAACGTCACATGGGTATTCATACTGGTGAAAATAAGTCTGAGTGTGGAATTTGTAAACGACAATTTACCAGATACTATTTAAAAAGACACATGGAATTTCATACTGGCGAAAATATGCAGGAGTGTAATATTAGTCAACGAAAATTTACTACAAAGAAGAATCTGATGAAGCACAAGCGGTGTATTTCTTCTGCTAACATCAGCCAAACAAGTTTGAAGCTACCATTGGTACTAAAAAGCCAGAAGTATATTTCTtccggtaaaaaaatatatgaatgtaatatctgtaaagaaaaatttttggaattatcTAATTTGAAAATGCACATGCGTATACATTTAGGCGATAAGCCGTACGAGTGTAATATTTGTCAACGAAAATTTACTGAAAAGAGTAGTTTGACGAGGCACAAGCAGCGTTTCCATACCACACATGACTGTATTTCTTCTAATAAAAAACCGTATGAGAATAACATCAGTCAAAAAAGTTTGAAGCTTCCGTCGATACTGAAAAGCCTCGAGTATATTTCTtccggtaaaaaaatatatgaatgttATTTCTGTGAAAAAAAGTTCGGTCAAGAGAATAGTCTAACATTTCACATGTATACGCgtcattataacaaaaaaacgtATGAGTGTAAGATTTGTCAAGCAAGTTTCAAACTTCTGATTGAACTTAATTTTCACCTGTTTCTTCACAAATACACAAATTTGTACAAATGTGATATCTGCCGAGAAGCATATATTATAAAGGATTGTTTGAAACAGCATATGTATACACATACCGGCGAAAAATTTTACGAATGCATTGTTTGTCTTAAAGAATTCTCTCGGACTGGTCTGAAACGCCACATCCAGAACATTCACGTTGACTACAATCGATATACAGGTGACAATCCAATCAGTTAA
Protein Sequence
MGIHTGENMHECHICLKKFNTASNMKLHMRIHTEKTSYECKVCKKKFTRKHSLKSHMGIHTSENKSKCEICKRQFTRYYLKSHMKIHTGENMHECNICRKKFSTTSNMKLHMRIHTGTTSYKSYKCDICNKKFTSKRSQINHMSIHTVENKSECRICKKKFTRNENLKIHMVIHTGENMCECEICKKKFTRKENLKIHMVIHTGEKMYECKICKKKFTRKDYLGRHMVIHTGEKMYECGICKKKFTTKYHLKSHMGIHTSENKSECEICRRQFNRYYLKSHMKIHTGENMHECNICRKKFSTTSNMKFHMRIHTGTTSYKSYKCDICNKKLTRKDYLKSHMGTHTGENMYECDICKKKFTKNDYLKSHMGIHTGENIKDNLERHMGIHTGENKSECGICKRQFTRYYLKRHMEFHTGENMQECNISQRKFTTKKNLMKHKRCISSANISQTSLKLPLVLKSQKYISSGKKIYECNICKEKFLELSNLKMHMRIHLGDKPYECNICQRKFTEKSSLTRHKQRFHTTHDCISSNKKPYENNISQKSLKLPSILKSLEYISSGKKIYECYFCEKKFGQENSLTFHMYTRHYNKKTYECKICQASFKLLIELNFHLFLHKYTNLYKCDICREAYIIKDCLKQHMYTHTGEKFYECIVCLKEFSRTGLKRHIQNIHVDYNRYTGDNPIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01006450;
90% Identity
iTF_01006450;
80% Identity
iTF_01006450;