Basic Information

Insect: Microplitis manilae
Gene Symbol: mecom-a
Assembly: GCA_030273425.1
Location: CP092726.1:23979405-23991425[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.00061 0.094 14.3 0.0 2 23 141 163 140 163 0.95

2 9 1.4 2.1e+02 3.8 0.1 1 23 170 193 170 193 0.91

3 9 2.6e-05 0.004 18.6 0.8 1 23 199 227 199 227 0.95

4 9 4.6e-06 0.0007 21.0 2.6 1 23 233 255 233 255 0.95

5 9 2.8e-05 0.0043 18.5 5.0 1 23 261 283 261 283 0.99

6 9 0.013 2 10.1 1.0 3 21 292 310 290 311 0.93

7 9 6.6e-09 1e-06 29.9 1.2 1 23 653 675 653 675 0.99

8 9 8.7e-07 0.00013 23.2 3.2 1 23 681 704 681 704 0.97

9 9 9.7e-06 0.0015 20.0 3.4 1 23 710 732 710 732 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.00061	0.094	14.3	0.0	2	23	141	163	140	163	0.95
2	9	1.4	2.1e+02	3.8	0.1	1	23	170	193	170	193	0.91
3	9	2.6e-05	0.004	18.6	0.8	1	23	199	227	199	227	0.95
4	9	4.6e-06	0.0007	21.0	2.6	1	23	233	255	233	255	0.95
5	9	2.8e-05	0.0043	18.5	5.0	1	23	261	283	261	283	0.99
6	9	0.013	2	10.1	1.0	3	21	292	310	290	311	0.93
7	9	6.6e-09	1e-06	29.9	1.2	1	23	653	675	653	675	0.99
8	9	8.7e-07	0.00013	23.2	3.2	1	23	681	704	681	704	0.97
9	9	9.7e-06	0.0015	20.0	3.4	1	23	710	732	710	732	0.99

Sequence Information

Coding Sequence: ATGGATCTCCAGATAACAATCAGCGCCCGTAATCCACCACGAACGGGTCCATTGACAATGATGGGACCTGGAACGTTACCGATTATGGATCCCTATTCATCGgtacGCGTTCCCGGAAACGGAGTAAGAGGATGGCTGGATGCCTCACATGAGCCGAGCAATTGGCTTAAATATATTCGCAGCACCGCCAGTCCACATGCTGTCAATATGCGTCATGTTCTCGTTGCCGGACAgATGGTCTACGAAACATTGAGAGATATATCAATAGGAGAAGAATTACTGATGGGTCTACGAGAGCCGCTTCAGTTGCAGGATATGCTGGGCGAGAACACGACTGAAGACAGGACAGACCGCGAGACCGCATCGCAGCACAGTGGAACTGTTGATGAGGATCGTGAGGACGAGGAGGATTGTGAAATACGGTGTCCAGTTTGTGATAAACCATTTCAAGATCTTGAATTATTAGATAACCATTTGGTAACAGGACATCGTTACCCATCGGACCAACACATCTGCGACAGCTGCCCGCGTGCATACGCCTGGCGCCCACTACTTGTACGTCACCGGGCAATAATACACGGTGACCTACGGAAATATCCTTGCGAGAACTGTCCAAAGTCAAACACGTCTCAGGTCTTCACAGATCCATCGAATCTCCAGCGACACATCCGGACGAACCACGTGGGAGCTCGCAGCCACGCGTGTACTGAGTGCGGCAAGACTTTTGCTACAAGCTCAGGATTAAAGCAGCATACTCATATTCACAGCAGCGTCAAGCCATTCCAGTGCGAAGTCTGCTTCAAGGCGTACACCCAGTTTTCAAACTTGTGCAGACACAAGCGCATGCACTCGACCTGCCGCATGCAGCAGAACTGTCTTCGTTGTGGCCAGTCATTTAGCACCGGAACTTCTCTGTCTAAGCACAAACGCTTCTGCGACTCGACTTCAGCGCCAGGTACACCAGCAGGACCAAGACCTGGTGCGATGCCTCAACTACCAACGGCGACGTCTTCAAATCCTTTCCTAGTTTATCAACGTCAACAACTGGGACCTGGATTGCCATTTTATCCTCATAATCTGATGCCTCCTTATCCGGGACTCTTTCCTAATGCACCAAGTTTTCTTAATACTCCTTTGCTATTCCCTCCTAAACTCCAGCAACAGTCTCAGCAAATGCCACAGCAATCGCAACCCCAGCAGTCACCTCGGCACCAAGAAGAAATCAAACGCTGTGAAAGTCCTAAGAAAGAGCGATTCACTCCACCGCAGCTGCCACCCCAGTCTAGCAAAATATCTCCGTCAATGGCCGAGGAAGCTACGTCGACATTCAGGCCTTCTCCAGCGAGGCCCACAGTCCAAGTGACGCCTACTCCAGACAGCGATGAAGACAAACGGATCCAAGAAACTAAGGTAGTCAAGCGAAAACTGGAAACCGATTCAAGCGAAGGGGAAGCTGAACAACCGCTCGATCTTCGAGTAATGAAACCTAAAATAGCTGCGCCAGAGACGCCGAGTCCACCACCAGAACCAGAACCAGTTAAACAAGAGAAAGAAGACGAGAAAATGGAGATCGAGGTTAAGGCTCCGAGTCCTAGAGTTTCTCATCACGAGAATCCGCCGACTCCACCGATGGCCTACCCAAGACCAATTCATCCCATGTTTTTGGAAGCAATGTACCGACCAACTGGCACATTTCCGGGGTTTCCAGCGCCACCTCCACCGCCGAATCACAATGAGTCACGCCTACTGCCACCTTTGCACCCATTCGGACCTCCAAGGATTCCTTTTTTAGGGAATCTCATGAACGGACTGAGCGGCGCTCGCGGTGAGTTCGATTTACTCTCTCGTACGCCTCTCGGTGCGTTTCCCGTCAAGCCCTTTCAGAACGTCATGTCCCAACACCATCCTCACCCGCACTCACACCACCACCACGTCTCTGGCAAAGTCAAAGACCGGTACTCGTGCAAATTCTGCGGTAAAGTATTTCCCCGAAGCGCGAACCTCACCAGGCACCTGCGGACACACACCGGGGAGCAACCCTACAAGTGCAAACACTGCGAAAGATCCTTCAGCATCTCCAGCAACCTTCAACGGCACGTGAGAAATATCCACGACAAACAGCGACCCTTCAAGTGTCCCCTCTGCGAGAGATGCTTCGGCCAGCAGACTAACCTAGACCGGCACCTCAAGAAGCACGAGGCCGACGACGGTAGCGTTGTCGTCTCCGTCGCCGACTCCCCAAGCAGCAGCAACGACAACGAGCGCGAGGACACTTACTTCGACGAAATCAGATCATTCATGGGAAAAGTCACCTACGGAACCGACAGTGGCTACGGATTAACCCATCCTGCCTACCTCCCACCCAGACTCGACGGCAAGGAGCCCGATTACGACGACGACGAGTACAGCGAAGAAGGTGTCTCTCCGTTGGACGAAACCGACGCGTTATCAGTCGAGGGTAAAGAGTCTCCGACTCAACAGTACGAACTAAAGTGCAGAAACAAACAGGAATTACTTAACAATAATACCGCTGAGCCTGTTATCGAAATCTCGACATAG
Protein Sequence: MDLQITISARNPPRTGPLTMMGPGTLPIMDPYSSVRVPGNGVRGWLDASHEPSNWLKYIRSTASPHAVNMRHVLVAGQMVYETLRDISIGEELLMGLREPLQLQDMLGENTTEDRTDRETASQHSGTVDEDREDEEDCEIRCPVCDKPFQDLELLDNHLVTGHRYPSDQHICDSCPRAYAWRPLLVRHRAIIHGDLRKYPCENCPKSNTSQVFTDPSNLQRHIRTNHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHSTCRMQQNCLRCGQSFSTGTSLSKHKRFCDSTSAPGTPAGPRPGAMPQLPTATSSNPFLVYQRQQLGPGLPFYPHNLMPPYPGLFPNAPSFLNTPLLFPPKLQQQSQQMPQQSQPQQSPRHQEEIKRCESPKKERFTPPQLPPQSSKISPSMAEEATSTFRPSPARPTVQVTPTPDSDEDKRIQETKVVKRKLETDSSEGEAEQPLDLRVMKPKIAAPETPSPPPEPEPVKQEKEDEKMEIEVKAPSPRVSHHENPPTPPMAYPRPIHPMFLEAMYRPTGTFPGFPAPPPPPNHNESRLLPPLHPFGPPRIPFLGNLMNGLSGARGEFDLLSRTPLGAFPVKPFQNVMSQHHPHPHSHHHHVSGKVKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKHCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSVVVSVADSPSSSNDNEREDTYFDEIRSFMGKVTYGTDSGYGLTHPAYLPPRLDGKEPDYDDDEYSEEGVSPLDETDALSVEGKESPTQQYELKCRNKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01006505;
90% Identity: iTF_01006505;
80% Identity: iTF_01003745;