Mdep027058.1
Basic Information
- Insect
- Microplitis deprimator
- Gene Symbol
- bab2_5
- Assembly
- GCA_964016945.1
- Location
- OZ024714.1:15847969-15849454[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.7e-23 3.9e-21 76.3 0.5 1 86 35 117 35 122 0.92
Sequence Information
- Coding Sequence
- ATGGAGGCTGCTCGTTACTGGGGTGTTCACTACAgCGGAGGGATGGCCGGGCAGCATTACTGCCTGCGCTGGAACAATTACCAGTCAAATATGACCTCAGTGTTCCACCAGCTTCTGCAAACGGAGGCTTTCGTGGACGTGACACTTGCCTGCAACGAGGCATCGTTAAAGGCGCACAAGgtcGTGCTATCAGCATGCAGTTCATACTTTAAAAAACTCCTGCTATCAAACCCCTGCAAGCATCCGACGATAATAATGCCCCAGGACGTGTGTTTCAACGACCTGAAATTCATAATAGAGTTCGTCTATAAGGGGGAAATAGACGTGTCCCAAGCGGAACTTCAGGATATCCAGATTCTAGATGATACAGATGATCAATCACCCAGATTCCGATGA
- Protein Sequence
- MEAARYWGVHYSGGMAGQHYCLRWNNYQSNMTSVFHQLLQTEAFVDVTLACNEASLKAHKVVLSACSSYFKKLLLSNPCKHPTIIMPQDVCFNDLKFIIEFVYKGEIDVSQAELQDIQILDDTDDQSPRFR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00997164;
- 90% Identity
- iTF_00905537; iTF_00721388; iTF_01364785; iTF_00058839; iTF_00058076; iTF_01497601; iTF_01129479; iTF_01509008; iTF_00438880; iTF_00343306; iTF_00997164; iTF_00996482; iTF_01103693; iTF_00265872; iTF_00379765; iTF_00381224; iTF_00629237; iTF_00168634; iTF_01273916; iTF_00380477;
- 80% Identity
- iTF_01129479;