Mdem009220.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Microplitis demolitor
Gene Symbol
BTBD7
Assembly
GCA_000572035.2
Location
NW:102835-116540[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 3.1e-14 3.5e-12 45.8 0.0 4 87 161 244 158 268 0.82
2 3 9.6e-06 0.0011 18.5 0.0 22 49 301 329 297 370 0.72
3 3 2.2 2.5e+02 1.2 0.0 72 107 391 427 383 430 0.86

Sequence Information

Coding Sequence
ATGAACGTATTAAGGATTTTAATACCGTGCGCGTTGCAGCGAGGCGAAGAAAGTGACGTTAACAATAGAACTGGGTGCTGGTCATCACTAGGAAAAaggaataataatgatgatgtaCGTATGACCCATAGGATGGGAGCATCGGCCTCTTCGAATCTAGCCGCTGTCGGTGGTGACCCGATACAAGCGGCAAGACTTTCATCTTCTGGAAATCCGGATCAGTTCAACATCGGCATCAGGGAGCGAAAAAAGAAAGTAACTGGTTTCGCGACTCTAAGGAAGAAGTTCATCCGGAGACGGCGCTCGTCAAAGGCATGTGACCACGGGCGAGTGATACGCGAGCTAGTGTCGACCTGGAGTCCGCTGGAGGCGTCAGCACTGCTTGAGGAGTATGAGGCTCTCGCTGCACTTAAAGACCTTCACGTACAAGCAGAATTGGCGCGCCCACCGGCAGCTACTTTCAAACAAGACTTGTCAACTTTGTATGACTACAAACACTGTACGGACGTTGATCTAGTCTACCGCGGTGCGTGTTTTCCCGTGCACCGCGCACTACTGTCAGCAAGATGTCCGTACTTCCGAGAGCTGCTGTCGGGATGCCCGGGCTATGGAGCGCGAATATGCTTGGAGTTGCGAACGCCGAATCTAGAAGTCCATATGTTCTCGGCACTACTGCGTTACCTGTACACTGGAGACATTTGTTCCCATGACACATCGTTGGATCCAAGTCTGCTACGGCGGCTGGGTGAAGAATTCGGAACTCCGAACCACTTGGATCACGATCTCCGTTACTTGCTGGATACTGGGGATTATGCAGACGCGGCGCTAGTCTTCACGTCTGACGGCGACTACCAACGACCTGACAGTGGCAGCTCCGAGTACGGATTTCGTCCGAAACTCGAGCTGCCCTGCCACAAAGCAATTTTGTCAGCTAGGTCAACATTCTTCCGCAACCTCATACAACGACGGACGCGTTCTGGTGAAGATCACACTGAGCGGGCGCTTCATATACCTACAAGAATTGTCTTGGACGAGAGCGTTATTCCTAAAAGATACGCGCGAGTGCTTTTGCATGCCGTTTACTTGGACACTGTGGACCTGTCGTTGATATTGAGAGGCAGCGGTTGCGGGAGCAGTACCGGGAGTCTCGGTGAAGTACAAGCGTTAACACATACCGGGCGAATGCGGCCAAGTCCGCTGGAAGAAGCCATGGAGCTGTACCAAATCGGGCGGTTTCTAGAGCTTGACATTCTGTCCCAAGGTTGCGAAGACCTAATTCTAGAGTGTTTAACCCAAGAATCACTGCCTACTGTCCTGAGGTGGGGAAGTCAACCGCACGGCTCGGCATGGGTCCATAGACAAGCGTTGCACTTTCTCAGAGAAGAGTTTCAATCGATAGCTTCATCGCCAGTTCTATTTCAGTTAGACCACGTACACCTAGCTCAGTCTCTGCAAAGTCATTTTCTCCAGGCAAGCGAGCTGGAAGTACTTCAGGCCGTACTAAAGTGGGGCGAGCAGGAGCTGGTGCGACGCATGGAAGATCGCGAGCCAAATATACTCAGCCACACCGTGCACTCTGTCACACGCAAAGGCGTCAAGAAACGCGATCTCAGTGACATCGAGCTACGGGAAATTCTCAGCGAACTTTTACCTCTCGTCAGAATGGACCACGTGCTTCCACCCAATAACGAAATCCTCACTCAGGCTATAAGAAGAGGCCTGGTATCAACGCCGCCGAGTCATATGATCGGCGACGAGCGtgaaaatttacgaatcaACGCGTGGATCAGAGGAGGGAAAAGAAATGGACTATTTATACGGCCTCGTTTATTCATGCCCTACTATGAGGAAATAaagAGTCTAGTCGAAGAACACATGGTACAAGAAGCAGAATTAGTTAGATTAAGAAGGGCGCGATACATTCCCGACATACCAGATACATTGTACATGGTAGATGAGAAACCGCGATCAATGGGCACTGCTGGTGTTGATGTTCTCGCCGCAGCTCTTCCTGTTCCAGACGCAGTAACAATGTCAGCGATGTTGAAACGGGAGCAAAAACTTCGTCAGTCTCCAAGCTGTCAACGCGCTATGACTCTACCGTTATCTTGCCGGCACGAGATCAGCAGACAAGTGAGACTACGCGTCGTACGGGAGTTCAATTTACCTGACGCGGTTGCCGATCTCCTTGAgaatgcTGCGTGCTACAATGCTGAGCAAGAAGAATCCATGACGGACATGGAAAACATGGAACCAGTTAGCACTGGAAGTATTAATATTAGCAGTACTTCTGCAGCATGTTACGGCCGAAATATGACTTTCCCGCGACCAAACTCCTCATATGGAATTAGACACGAACTTCCTGCTGTGGTTACTGAGGGAGAGAATTACAGACTTCCAGGagagCCGTCACCGAACAATCAATGCAATGACGGGCACTTATCGGGCATAATGCCTGACGTAGCGATGGCAACAGCTTCATTCGGAGCTCTCCAGCTAGCAGATCAGCAAGAACTGGAACTTGATCTCGGAGACGGTGCGTCGCATCTCCTGCATCCCGGGCCGGCACCCGGTTCTGCCGGAGTCCATCACCCACTGCTTCCTCACCAGAGGCAAAGACACTACGCCGGGCTTCCACCGCATCCTTACATGTATCATCGTTCCAACACCGGCTTACCGAGGTTCATTTGA
Protein Sequence
MNVLRILIPCALQRGEESDVNNRTGCWSSLGKRNNNDDVRMTHRMGASASSNLAAVGGDPIQAARLSSSGNPDQFNIGIRERKKKVTGFATLRKKFIRRRRSSKACDHGRVIRELVSTWSPLEASALLEEYEALAALKDLHVQAELARPPAATFKQDLSTLYDYKHCTDVDLVYRGACFPVHRALLSARCPYFRELLSGCPGYGARICLELRTPNLEVHMFSALLRYLYTGDICSHDTSLDPSLLRRLGEEFGTPNHLDHDLRYLLDTGDYADAALVFTSDGDYQRPDSGSSEYGFRPKLELPCHKAILSARSTFFRNLIQRRTRSGEDHTERALHIPTRIVLDESVIPKRYARVLLHAVYLDTVDLSLILRGSGCGSSTGSLGEVQALTHTGRMRPSPLEEAMELYQIGRFLELDILSQGCEDLILECLTQESLPTVLRWGSQPHGSAWVHRQALHFLREEFQSIASSPVLFQLDHVHLAQSLQSHFLQASELEVLQAVLKWGEQELVRRMEDREPNILSHTVHSVTRKGVKKRDLSDIELREILSELLPLVRMDHVLPPNNEILTQAIRRGLVSTPPSHMIGDERENLRINAWIRGGKRNGLFIRPRLFMPYYEEIKSLVEEHMVQEAELVRLRRARYIPDIPDTLYMVDEKPRSMGTAGVDVLAAALPVPDAVTMSAMLKREQKLRQSPSCQRAMTLPLSCRHEISRQVRLRVVREFNLPDAVADLLENAACYNAEQEESMTDMENMEPVSTGSINISSTSAACYGRNMTFPRPNSSYGIRHELPAVVTEGENYRLPGEPSPNNQCNDGHLSGIMPDVAMATASFGALQLADQQELELDLGDGASHLLHPGPAPGSAGVHHPLLPHQRQRHYAGLPPHPYMYHRSNTGLPRFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00378163;
90% Identity
iTF_00687334; iTF_01004461; iTF_00379769; iTF_01006393; iTF_01005372; iTF_00938152; iTF_00378994; iTF_00382004; iTF_01001524; iTF_00996485; iTF_01000712; iTF_01560584; iTF_01002218; iTF_00997167; iTF_00452054; iTF_00316922; iTF_00317577;
80% Identity
-