Mbra001742.1
Basic Information
- Insect
- Microctonus brassicae
- Gene Symbol
- topi
- Assembly
- GCA_940306215.1
- Location
- OW675801.1:15750605-15752900[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.53 54 4.7 3.3 1 23 240 262 240 262 0.89 2 16 0.0052 0.53 11.0 4.2 1 23 268 291 268 291 0.97 3 16 0.00014 0.014 15.9 0.6 2 21 298 317 297 318 0.93 4 16 1.8e-05 0.0019 18.7 0.4 1 23 325 347 325 347 0.96 5 16 1.8e-06 0.00018 21.9 2.6 1 23 353 375 353 375 0.96 6 16 3.9 4e+02 2.0 1.8 2 15 387 400 386 408 0.82 7 16 0.12 12 6.7 3.2 1 23 424 446 424 446 0.97 8 16 0.0063 0.64 10.7 0.7 1 23 452 474 452 474 0.97 9 16 0.00058 0.059 14.0 1.5 1 23 484 508 484 508 0.92 10 16 1.1 1.1e+02 3.7 0.1 1 20 523 542 523 544 0.85 11 16 0.0015 0.16 12.7 0.1 1 23 549 571 549 571 0.98 12 16 7.4e-07 7.6e-05 23.1 2.1 1 23 577 599 577 599 0.98 13 16 2.8e-05 0.0029 18.1 0.6 1 23 605 628 605 628 0.97 14 16 0.044 4.5 8.1 0.7 1 23 634 656 634 656 0.89 15 16 6.9e-07 7e-05 23.2 1.1 1 23 662 684 662 684 0.99 16 16 1.2e-05 0.0013 19.2 6.3 1 23 690 713 690 713 0.98
Sequence Information
- Coding Sequence
- atgaaTTGGGGATTCGTAAATACAATACCGCTTAATGAAGACGTTGAAACTGATGTAAATACCATGGAGGATTTAATGATCTTGTCTCGTGATAATTTATCTGcacttaataaaattaatgaatcggatggaaaatttacaaatacacTTTGTTATATATGTGCTCGTCCAACAACCATtgatccaatttatttttacttcgaTTCAGAGGTGTCGTTGGAACTTGCCAAAACTAATAATTTAGAATACTTCGGAATAAagATTCAACAAGAAACAGATTCTCTGCCAAGACAATTATGTGAAGATTgcattgaaagaataaattgcaataatgCATTTGGAATAGAGTGTTTACAAGCTAAAGACAAATTTCCATTAATATTAGAAGAGGCAATattgaatgaacaaaaattgaataatgataatcAAAATATGGAATGTTTGGACCGtgaattgaattcaattagTGATGAGGATTCTAACAAAACGTCTAAACATGAgataaatatcacaaataatgctgaaaaaaatttattggaacCTTTTCCATCGGTAAATCCAACAATGTTTTGTGAAAAACAGTTCATGACATTTCAATGCCTTGGAAATGATCGTCAGTATTTAAAATGCAATGCTTGTATGactttattttatgataaaatctCTTTAGATAATCACAAATGCAAACCGCTAATTCCGAACATATCATTCAAATCTTACAAATGTTCAACATGCAATGCAGTATTTTCTCTTGAGGAGTGTTTGAATTTTCATCGTCAATTTCATCAGAAATCTCACGAtttcaattgtaatatttgcaatattaaGTTCAAGAAAGAACAAaagttattttatcattataaacgTTATCATTGCAATAGCACAACAATTTCTTGCCTCCAAtgtggaaaattatttgataatcaGTCACAACTTCGTGCTCATATTTGTAATGATGGCAAAATACGTCAGcatatttgtgaaatttgCAATAAAGGCTTTGCCGATGGATACACATTGAAACGTCATATTGTCACCCATTTGCCAGAAAAACCATTCAAATGCAATCAGTGTACAAAAAGTTTCACACAAAAATCCCGACTTAATAAACACATTGCAGATCATGAagtaattattgaagaatcaCAAACATGCTGGAAGTGTTTAGAATGCGGTATGATATTTCCAAGCTGCAAAGAAGCTGATGAACATTGTGAATATCATGAAAATGCAATCAGAATAATGGAAGAATTATCaatcacaaaaatttatcactgtgaattttgcaataattattttgacaatATTCAAACTCTGAAGATTCATCAGAGCAATCATTCAGTTGAAAATCCATTCAATTGTACTATTTGTAAGATAGAATTTAAGTCATTTACTGAAGTTGTGATACATTGGAAAAAGCATCCACGTATTTTCAAAGTTTTGACCGTTTTCTCGTGTgatatttgtgataaaaatacaaaagaccTGGctcttttatataaacacaaaagaAAACGACAACATTTTACCCCAAAAAAGTCTTCaattaatgataaacaaatgcaaTATTCATGCGAACTTTGTGGtggaatttttgataaattagaAGGAATAATACACCATAGTAAAATGCCGTGTTCAAAATTTCCATGTGACATTTGTGGTAGTCTTTTACCTACAAATGATTCTCTCGAAGCTCATAAAAGACGTCACAATGGATTACGTCCATACGTTTGCAATATCTGTGGAAAGAGTTATACACAATCAAGTCATATGTGGGCACACAAACGATTTCATATGGGAGTAAAACCTTATGCTTGTgaatattgtgataaaaaatttacaataaaaccCGATTTAGCTGATCACACTAGAAAAAAGCACACACGTGAACGACCATTCAAATGTGAGGTTTGTAATAAAGCATTTCTCACTGGATCCGTTTTCTATCAGCATCGTTTGATACATCGGGGCGATCGAcgatataaatgtaattattgtCAAAAGACATTTGCTAGAACAGAAGCATTAAATAATCATGTTAAAATACATACTGGTGAAAAGCCACACAAATGTGTCATTTGCGGAAGATGTTTTCGGCAAAAAGGTGACATGAGAAAGCATAAACGTACCCAACATGctattgaaaatgataaattggtAATCAATGGACAAATTGTCATGAGCATTGAAGAAATCATAGAAATTATCGATACTCCATAG
- Protein Sequence
- MNWGFVNTIPLNEDVETDVNTMEDLMILSRDNLSALNKINESDGKFTNTLCYICARPTTIDPIYFYFDSEVSLELAKTNNLEYFGIKIQQETDSLPRQLCEDCIERINCNNAFGIECLQAKDKFPLILEEAILNEQKLNNDNQNMECLDRELNSISDEDSNKTSKHEINITNNAEKNLLEPFPSVNPTMFCEKQFMTFQCLGNDRQYLKCNACMTLFYDKISLDNHKCKPLIPNISFKSYKCSTCNAVFSLEECLNFHRQFHQKSHDFNCNICNIKFKKEQKLFYHYKRYHCNSTTISCLQCGKLFDNQSQLRAHICNDGKIRQHICEICNKGFADGYTLKRHIVTHLPEKPFKCNQCTKSFTQKSRLNKHIADHEVIIEESQTCWKCLECGMIFPSCKEADEHCEYHENAIRIMEELSITKIYHCEFCNNYFDNIQTLKIHQSNHSVENPFNCTICKIEFKSFTEVVIHWKKHPRIFKVLTVFSCDICDKNTKDLALLYKHKRKRQHFTPKKSSINDKQMQYSCELCGGIFDKLEGIIHHSKMPCSKFPCDICGSLLPTNDSLEAHKRRHNGLRPYVCNICGKSYTQSSHMWAHKRFHMGVKPYACEYCDKKFTIKPDLADHTRKKHTRERPFKCEVCNKAFLTGSVFYQHRLIHRGDRRYKCNYCQKTFARTEALNNHVKIHTGEKPHKCVICGRCFRQKGDMRKHKRTQHAIENDKLVINGQIVMSIEEIIEIIDTP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01002283;
- 90% Identity
- iTF_01000766;
- 80% Identity
- -