Marg034009.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Metopia argyrocephala
Gene Symbol
Rfx2
Assembly
GCA_963576795.1
Location
OY756211.1:104721612-104724092[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 6.7e-38 8.9e-34 117.1 0.1 3 78 327 402 325 403 0.97
2 2 2.9 3.8e+04 -3.5 0.0 28 36 507 515 491 521 0.69

Sequence Information

Coding Sequence
ATGAGTACCAGATTGGCAGCGcctagaaattttgttttaacatcGTCTACTGCAACCGGAATAATAAATTCTCCTACTTTGACTGTTGTGTCCCCAGCTACGGATACTATAACAACCGAGTCGGCAACCGTTTTACCATGTGTCGTGAACACCACAACAGATTCAACGGCACTCGTGGTAACTAGGGAGCCCTCGTTTTCTATGCATAGTACACAACATGAGGAGTATCAATATATTACAACTGAATCTTTGCAAGATGTTATGACAACGCACAAGTCTTTGGCGGTAGTTGAACAAcatcagcagcaacaacaacaccagCAGCAGTTCTCCACTGATATTCATCATCAGCACCAGtatcaacagcaacagcaggAAGAGTTGGCTGTAATAAATGTTGTTGTGCCCATGGATAATACTGATGCTTCTAGTAATGAAGCTTCACAAGCAACCATGGATACTATAGCAGCTATTAAAGAGGGTGTAGTTGATTTAGTACATCACACAGATCAGGATGAAGGCTGTCCCCAATATATTACGGTTACCGTATCTACACAAGATGCTGGCCAAAACTATCAAGTGCAATATTTGGATGCTGAACAGTTATATCAGGCAACCAATGCTACACAAACTCAAATTACATATCCTTTTTGTCCAGTACAGGAATATCAGGCAAATCAGTCTACATTCTATACTACAGCAACAGAAAATTTTGCAAATGAAAGCACACTATTAACGGGTAACACTACACATGCCACGAATCTTTTGCCGTACTTAGTGCCTGTAGAAGAAAGCATGTTAATAAATACTTCTCCCGAAGATATGCAAAACTCTCCCCTAACACCAAACTCATCGAACAACACCACTATGGTGGGTGGTGGTACACAATGCATAAATTCATCCAATGAACAAGAAATCGATGATAATTCTATGGAAACTGATGCTAATCAAGCCGGAGGTTCAAATAAAATTGCCTCAGCTACCATAAAATGGTTATCACAGAACTATGAAACTGCAGAGGGTGTTAGTTTACCCAGATCTACCCTATATAGCCACTATATACAGCACTGTAATGAGTGTAAACTTGAGCCGGTAAATGCAGCCAGTTTTGGCAAGCTAATTAGGTCTGTGTTTTCGGGTTTACGCACACGTCGTTTGGGTACTCGCGGCAATTCTAAATACCACTACTATGGCATACGCATAAAACCGGATTCACTACTGAAACAGCAACAAACTAGTAATGAAAACTCGTGCTCCAGCTCACCAACAAAGACTTCTTCTTCCCCATTTATAAACACCAGCTCTTCAAGTCATGCTTCAACGTCTGGTTGTTCTTCCAATCATCAACATGGCCCTAATAAATCaactaaaaagttaatttttaaaccaGAATTCTATGCAGCTTGTGCTCAATATTTAGGTGATGGCACTGGCGCCATGCCAACTTTTCCTGTACTAGAATTAGATCACACTTATCAGGCTGATATCACCGTACAGGATTTAGAATTATTTCGTTTGAAATATCAAGAACattgtgaaaaatttttagATGCCATTGTTAATCTggaatttaatacaattgaacACTTGTGGCGTGAATTTTGGTCAATCGATCATCATAATTCTCTAGAAAATCTTGCACATTCGAAGTTGCAATTGCTTTGTGTCTCTACTACAGTACAAAATTTTGTACGTGATGTTGACTATCAATTCTTTCAAAACCTGGTTGATGTTATTGTGCCAGATGTCCTGAGATCTATACCGAATGCTTTGACCCAAGCCATTAGACGTTTTGCCAAAAATATGGAAGCATGGTTGTGCGAAGCCATGAAGGGTATACCCGAACAAATGACACAGATTAAAACATCAGTTGTATCAGCATTTTGCCAGACCTTACGACGTTACACATCTCTTAATCACTTAGCTCAAGCTGCCAGAGCTGTACTACAAAATAATATGCAAATTACCCAAATGCTTGCCGATCTAAATCGTGTAGACTTTCGTAATGTACAAGAACAAGCCGCTTGGGTGTGTCAGTGTGATGCGGAAATGGTACAACGTCTAGAAAATGATTTTAAAGCAGCTCTGCAGCAACATAGCACCTTAGAACAATGGGCTTCTTGGATGCAATTGGTAGTGGACACTTCTCTGCAAGAATATCGTGGCAAACCCTATTATCCTAAAGCTGCCAGacaatttcttttaaagtgGAGCTTTTATAGTTCTATGGTTATTAAGGATTTAACTTTACGTTCAGCTTCTAGTTTTGGCAGTTTCCATTTGATTAGACTTCTGTACGATGAGTACATGTTCTATTTGGTAGAGCATAAAATAGCTGAAGCTCAGGAAAAAACAGCTATAGCTGTCATATGTGAACGTTTACAAAAAGATGTAGACTTTGAATTGGATTATCAGTTGGAATTAATAGCGACAGATGTTAACAATACAGAATCACAAGCTAAACGTGTAAAACATGagtga
Protein Sequence
MSTRLAAPRNFVLTSSTATGIINSPTLTVVSPATDTITTESATVLPCVVNTTTDSTALVVTREPSFSMHSTQHEEYQYITTESLQDVMTTHKSLAVVEQHQQQQQHQQQFSTDIHHQHQYQQQQQEELAVINVVVPMDNTDASSNEASQATMDTIAAIKEGVVDLVHHTDQDEGCPQYITVTVSTQDAGQNYQVQYLDAEQLYQATNATQTQITYPFCPVQEYQANQSTFYTTATENFANESTLLTGNTTHATNLLPYLVPVEESMLINTSPEDMQNSPLTPNSSNNTTMVGGGTQCINSSNEQEIDDNSMETDANQAGGSNKIASATIKWLSQNYETAEGVSLPRSTLYSHYIQHCNECKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPDSLLKQQQTSNENSCSSSPTKTSSSPFINTSSSSHASTSGCSSNHQHGPNKSTKKLIFKPEFYAACAQYLGDGTGAMPTFPVLELDHTYQADITVQDLELFRLKYQEHCEKFLDAIVNLEFNTIEHLWREFWSIDHHNSLENLAHSKLQLLCVSTTVQNFVRDVDYQFFQNLVDVIVPDVLRSIPNALTQAIRRFAKNMEAWLCEAMKGIPEQMTQIKTSVVSAFCQTLRRYTSLNHLAQAARAVLQNNMQITQMLADLNRVDFRNVQEQAAWVCQCDAEMVQRLENDFKAALQQHSTLEQWASWMQLVVDTSLQEYRGKPYYPKAARQFLLKWSFYSSMVIKDLTLRSASSFGSFHLIRLLYDEYMFYLVEHKIAEAQEKTAIAVICERLQKDVDFELDYQLELIATDVNNTESQAKRVKHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01315232; iTF_01313499;
90% Identity
-
80% Identity
-