Basic Information

Insect: Meteorus colon
Gene Symbol: FOXP4
Assembly: GCA_030523125.1
Location: JAPYZG010001614.1:25822-39710[+]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 7.9 6.6e+03 -2.7 0.9 23 46 158 181 149 203 0.68

2 3 2.3e-27 1.9e-24 85.5 0.7 2 66 613 676 612 678 0.97

3 3 1e-05 0.0087 16.1 0.0 49 82 677 705 675 710 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	7.9	6.6e+03	-2.7	0.9	23	46	158	181	149	203	0.68
2	3	2.3e-27	1.9e-24	85.5	0.7	2	66	613	676	612	678	0.97
3	3	1e-05	0.0087	16.1	0.0	49	82	677	705	675	710	0.87

Sequence Information

Coding Sequence: ATGCCATTATTTCAGGCAACAACACTTTACGCAGCCCTGAAGCAACAACAATCACATGATTTATTGTGGGAACGAGAACGTGGAGCAAAGAAAGCAAGAAATAGCGATCAAAGTGTTGGTACTGAAATTGAAGCTGATCAACACgatcattcaattaatacaaattatcGTAGCAATGGAAAACACAGTCCAATTGGACAAAACGCACTGACAATAGCATCCATGACCCAGCAAAAGCAGCCGATAATTTCACAACAATCACAACAACCCTGTTCCGTCACGCCTGGTGCACGAACAAGTCCTAACCAAAGTCCACAGGCACTTCAGCGTGCATCACCACCAAATCCCAATCAGGGATTACTGTCTGGTGGTCCACCTAGTGGTCCACCATCACAAAATTCTAATCAGATGATGCTCAGTCCGGCCAGTGGCCTTCATCATCAAATGCAACAATTACTGCAGCAACACATTTTAACACCAACACAGTTGCAATCGTTTGTGCAGCAGCATACGTTATACCTGCAACAAacacaacaacagcagcagcagcagcagcagcagcagcagcagcaacaacaacaacaacaacaacaacaacagcagcaacagcagcagcaacatcatcagGAATCGTCATCTGAACATGCATCAAATCAGGAGCGTTTCGGCTATTTTTCATCGTTAAAAAATCATCAACATCAATTGGCGGAACTAGGAAGGAAGCAATTGGAACAGAATATGCAGCAATTGCAAGAGCAgttacaattgaatttgattcaacaaACGCATCTACTACAAACGCCGGACAAGAAGAAAACTTCCGTGCCATTGCAACAGCTGAGTGTTCAACAACACCAAATTATCCAACAGCTACAAATGACACAGAGACAGTATCTATTCCAGCAGGGATTGAGCCTTCAGGGCCATAATCATTCCACCGGTACTCTGTCGATTGATACGATGCCAACGTGGAAATCAGAGCCAACAGATGGGACTGACACTCATCAAAATACCAGCGTCACAAAGTCCGGTGCGAGTTTGAACGGtctcatcaattcaattgtttcgAGTCGGCGATTAGATGTCAACGGATCCGGTGGATTAGATGAAAAACCATTCGATGTTGCCTGTAATGAAAAATCCCATCCCCTTTATGGCCATGGGGTGTGCAAATGGCCAAGCTGTGAAGTTATCTGCGAAGACTATCAAGCATTCCTAAAGCATATGAATACGGAGCATACATTGGATGATCGATCAACGGCGCAAGCGCGAGTTCAAATGCAAGTTGTGTCAcaattggaaattcaattgcaaaagGAACGTGATAGAGCAGCGGCAATGATGCATCATTTGCATGTAGCAAAACAAATGGCGTCACCTGAACCTCCCAAATCATCCGAGTCGTCGACAGGCTCAAGTTTAACAAAATTGAGTTTATCCTCGGGTTTGATGAGTCAGCCGCCGCCAAATTTTGGCGTATCACAGGTATCACCTGTCTCAATGTCGGCATTAGTGTCGGCAGTCAGATCGCCGGCTGGAGGACAATTACCCCCATCGGCCGGTGGTGCACCAATGCCGCCATTGTCAAGCTTATCAAGCATACCGGGTCTACCACCGATGCCAAATATGCCTGGAAGCTTATCGAATTTGCCTGGTGCTATGGCAAGCATGGCTGGACCCATTCGCAGACGAATTAGTGATAAATCTGCACTATCATTAGCTGGAGGCCTGTATGAGGAGGGGACTGCGAGGCGCAGAGTATCCATCGATAGATCTGGCATAGATATTAACGAAGaaattCAACGAAACCGagaattttacaaaaatgCTGATGTGAGACCACCATTCACGTACGCCTCGTTAATACGGCAGtcGATTATTGAGTCACCGGAGAAGCAGCTGACATTAAATGAAATCTACAATTGGTTCCAAAATACATTTTGCTACTTCAGAAGAAACGCTGCAACGTGGAAGaaCGCAGTGCGACACAACCTGTCTCTCCACAAATGTTTCATGCGAGTCGAAAACAACGCCATCCGCACCAATCTATCATTGCACAAGTGTTTTGTGCGCTATGAGGACGACTTTGGGTCATTCTGGATGGTGGACGACGCCGAGTTCGTAAAGCGGCGGCATCTGTCCCGCGGCCGTCCCAGGAAATATGACCCAACCCCATCACCCACTCCACCCCACCTCTCCGCACAGGGCGTACCATCAAAGAGTCCAACCCTGACGCACAGCCCAACAATGTATGGCGATGCACTCAATGCCAATCTCCAGTATTTTCAGGCTGCGTTGGGTGAGTCGAACATGGGATTTTTAACTAACTCGATGTGCACTTCGACAGCGACGAGTCCAGGCAAGGACCATGTAATGCCGCACAATGATTTAATGTCACCACTGGATGAACCAGGAATGCACATAAAACAAGAGGGTCAAAGTCCTGAGGGTGGAAAATTATCTAGATTAATAAAACGAGAAATGTTAGAGGCTCCAACGGATCATGATCATGAGGAGGATGCTGTTGATGATAGAGAATATCCTGAAAGTCATGGGCAAGACTCAGGTCAGGATGAGGATATGGCAGAAGATCTATCAATGGCGCCGGATATCGGCACATCGGACGATCAAATTGAGGCGTAG
Protein Sequence: MPLFQATTLYAALKQQQSHDLLWERERGAKKARNSDQSVGTEIEADQHDHSINTNYRSNGKHSPIGQNALTIASMTQQKQPIISQQSQQPCSVTPGARTSPNQSPQALQRASPPNPNQGLLSGGPPSGPPSQNSNQMMLSPASGLHHQMQQLLQQHILTPTQLQSFVQQHTLYLQQTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHHQESSSEHASNQERFGYFSSLKNHQHQLAELGRKQLEQNMQQLQEQLQLNLIQQTHLLQTPDKKKTSVPLQQLSVQQHQIIQQLQMTQRQYLFQQGLSLQGHNHSTGTLSIDTMPTWKSEPTDGTDTHQNTSVTKSGASLNGLINSIVSSRRLDVNGSGGLDEKPFDVACNEKSHPLYGHGVCKWPSCEVICEDYQAFLKHMNTEHTLDDRSTAQARVQMQVVSQLEIQLQKERDRAAAMMHHLHVAKQMASPEPPKSSESSTGSSLTKLSLSSGLMSQPPPNFGVSQVSPVSMSALVSAVRSPAGGQLPPSAGGAPMPPLSSLSSIPGLPPMPNMPGSLSNLPGAMASMAGPIRRRISDKSALSLAGGLYEEGTARRRVSIDRSGIDINEEIQRNREFYKNADVRPPFTYASLIRQSIIESPEKQLTLNEIYNWFQNTFCYFRRNAATWKNAVRHNLSLHKCFMRVENNAIRTNLSLHKCFVRYEDDFGSFWMVDDAEFVKRRHLSRGRPRKYDPTPSPTPPHLSAQGVPSKSPTLTHSPTMYGDALNANLQYFQAALGESNMGFLTNSMCTSTATSPGKDHVMPHNDLMSPLDEPGMHIKQEGQSPEGGKLSRLIKREMLEAPTDHDHEEDAVDDREYPESHGQDSGQDEDMAEDLSMAPDIGTSDDQIEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01000363;
90% Identity: iTF_00996155;
80% Identity: -