Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.83 6.4e+02 2.4 0.0 22 44 99 121 96 129 0.84

2 7 0.12 95 5.0 0.1 22 47 127 152 121 159 0.84

3 7 2.3 1.8e+03 0.9 0.0 26 48 187 209 181 213 0.82

4 7 0.38 2.9e+02 3.5 0.0 22 47 211 236 207 241 0.83

5 7 0.089 68 5.5 0.1 22 50 239 267 236 270 0.83

6 7 0.017 13 7.8 0.0 22 52 267 297 264 299 0.86

7 7 0.015 12 7.9 0.0 22 47 295 320 291 325 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.83	6.4e+02	2.4	0.0	22	44	99	121	96	129	0.84
2	7	0.12	95	5.0	0.1	22	47	127	152	121	159	0.84
3	7	2.3	1.8e+03	0.9	0.0	26	48	187	209	181	213	0.82
4	7	0.38	2.9e+02	3.5	0.0	22	47	211	236	207	241	0.83
5	7	0.089	68	5.5	0.1	22	50	239	267	236	270	0.83
6	7	0.017	13	7.8	0.0	22	52	267	297	264	299	0.86
7	7	0.015	12	7.9	0.0	22	47	295	320	291	325	0.85

Coding Sequence: ATGGATGTAGAACTTGAGATTAAGGAAGAGCCATTGGACAGAGATACACATTCACTTGAATTGAAATCAGAAATTAAGGAGAGAAGTTCTTATGATGCTGCTCATGGCATATTGTTGGAGTATGATATAAAGGAGGAGAAAGAGCTTGACATAGCTTTATTGAAGGATGAGATGAAAGTTGAGGAATTAAATGTTCCATGCTGTGATCCAGGCAATAAACtctataaatgtgaagtttgtgggaagcaCTTTACCAAAGTTTATTTGAAAAGCCATGTTTTAATACATGAGGGCAAAAAGCCCCATAAATGTGAATtgtgtgggaagagctttacccatgcTTCCAATTTGAGAAACCATCGTtttattcatgagggtaagaagcctcATAAGTGTGAAGTCTGTGGGAGGAGTTTTACACAGGCATCTCATTTGAGGggacatcttttaattcatggaGGTAAGAAGCCCCATAAGTGTGAATtctgtgggaagagctttacacgGGCATTCATTTTGAggggacatcttttgattcatgaaggcaagaaaTTCCATAAGTGTGAAGtgtgtgggaagagttttacccaGGTATCTACTtttaggaaacatcttttgattcatgagggcaagaagcccattaaatgtgaagtttgtaagAAGAGCTTTACCAAGGCATCACATTTgaggaaacattttttaattcatgagggcaagaagccccataaatgtgaagtgtgtggaAATAGCTTTATTCAGGCATCTCATTTGAGGaagcatattttgattcatgaaggcaagaaaccacataaatgtgacctatgtggaaagagctttacccagggATTTACcctaaggagacatcttttgattcatgaaggcaagaaaCCACATATGTGTGAAGtgtgtggaaagagctttacccagggATTCACTTtgaggagacatcttttgatgcacgaggtcaaaaaaaccacataa
Protein Sequence: MDVELEIKEEPLDRDTHSLELKSEIKERSSYDAAHGILLEYDIKEEKELDIALLKDEMKVEELNVPCCDPGNKLYKCEVCGKHFTKVYLKSHVLIHEGKKPHKCELCGKSFTHASNLRNHRFIHEGKKPHKCEVCGRSFTQASHLRGHLLIHGGKKPHKCEFCGKSFTRAFILRGHLLIHEGKKFHKCEVCGKSFTQVSTFRKHLLIHEGKKPIKCEVCKKSFTKASHLRKHFLIHEGKKPHKCEVCGNSFIQASHLRKHILIHEGKKPHKCDLCGKSFTQGFTLRRHLLIHEGKKPHMCEVCGKSFTQGFTLRRHLLMHEVKKTT

Sequence clustering based on sequence similarity using MMseqs2