Basic Information

Insect: Metallyticus violacea
Gene Symbol: tc1a
Assembly: GCA_030762175.1
Location: CM060830.1:30299402-30311314[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00025 0.031 16.5 0.7 1 21 133 153 133 154 0.94

2 15 5.2e-06 0.00063 21.8 1.9 1 23 161 183 161 183 0.96

3 15 1.9e-07 2.3e-05 26.3 1.8 1 23 189 211 189 211 0.98

4 15 1.3e-05 0.0016 20.5 1.0 1 23 217 239 217 239 0.97

5 15 3.9e-07 4.7e-05 25.4 2.1 1 23 245 267 245 267 0.98

6 15 7.3e-08 8.9e-06 27.6 1.2 1 23 273 295 273 295 0.98

7 15 1.9e-07 2.3e-05 26.3 2.1 1 23 301 323 301 323 0.97

8 15 2.6e-06 0.00032 22.8 4.1 1 23 329 351 329 351 0.98

9 15 2.2e-06 0.00026 23.0 1.5 1 23 357 379 357 379 0.98

10 15 3.1e-06 0.00038 22.5 0.2 1 23 385 407 385 407 0.97

11 15 1.1e-07 1.3e-05 27.1 2.9 1 23 413 435 413 435 0.98

12 15 1.3e-05 0.0016 20.5 2.4 1 23 441 463 441 463 0.98

13 15 0.0002 0.024 16.8 0.9 1 20 469 488 469 491 0.91

14 15 0.0023 0.28 13.5 3.3 1 23 497 519 497 519 0.98

15 15 1.2e-06 0.00014 23.8 0.6 1 23 525 547 525 547 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00025	0.031	16.5	0.7	1	21	133	153	133	154	0.94
2	15	5.2e-06	0.00063	21.8	1.9	1	23	161	183	161	183	0.96
3	15	1.9e-07	2.3e-05	26.3	1.8	1	23	189	211	189	211	0.98
4	15	1.3e-05	0.0016	20.5	1.0	1	23	217	239	217	239	0.97
5	15	3.9e-07	4.7e-05	25.4	2.1	1	23	245	267	245	267	0.98
6	15	7.3e-08	8.9e-06	27.6	1.2	1	23	273	295	273	295	0.98
7	15	1.9e-07	2.3e-05	26.3	2.1	1	23	301	323	301	323	0.97
8	15	2.6e-06	0.00032	22.8	4.1	1	23	329	351	329	351	0.98
9	15	2.2e-06	0.00026	23.0	1.5	1	23	357	379	357	379	0.98
10	15	3.1e-06	0.00038	22.5	0.2	1	23	385	407	385	407	0.97
11	15	1.1e-07	1.3e-05	27.1	2.9	1	23	413	435	413	435	0.98
12	15	1.3e-05	0.0016	20.5	2.4	1	23	441	463	441	463	0.98
13	15	0.0002	0.024	16.8	0.9	1	20	469	488	469	491	0.91
14	15	0.0023	0.28	13.5	3.3	1	23	497	519	497	519	0.98
15	15	1.2e-06	0.00014	23.8	0.6	1	23	525	547	525	547	0.98

Sequence Information

Coding Sequence: ATGGATTTGAGCAACACTTTCTTCAGGAAACAatggagcttccagcaggattcagcaccAGTTCACAAGGCAAAGTCTACCCAGGACTGGCTGCAGAGAAATGTTCCAGACTTCATTGCAATGGATGATTGGCCTTCCAGCAGCCCTGACCTGAACCCATTGTACAAGTTGTGGTCCATGCTTGAAGGCATGGTCTATAAGAAGAGTTATCCCAGTATCAACAGCCTTAAGCGCTCCTTGGTGAAAGCAGTGGCAGATTTTCCTATGGAGACTGTGCATAATTCCATTGATGCATGGCCACAGAGACTTAGGGCCTGTGAACAGGAACTTGACATAGCTGTAATGAAGGATAAGGTCAAAGTTGAGGAATTTAATATTCCTGGGGCCAGGAAGTCACATAAGTGTGAAGCTTGTGGAAAGAGCTTTTTCAAAGAATCTAGTTTGAGGCAACATCTTTTAATTCGTGAGtccaagaagccacataaatgtgaagtttgtgggaagagctttacataTGCATATTCATTAAGGATACATACTTTCATTCATGAGGGCACgaagcctcataaatgtgaaatttgcggAAAGAGCTTTACACAAGCAAAAACTTTGAGACAACATCTTATGATTCATGAGGGCAGAAAGCCATTTAAGTGTGGAGTTTGTGAAAAGAGCTTCACCCAGACAGCTCATTTAAGAGAACATCTTGTTATTCATGAATGCATAAAGCCACACAAGTgcaaagtttgtgggaagagctttgccCATCCATCTACATTAAGGATACATTtgttgattcatgaaggtaagaagccccataaatgtgaagtttgtgggaagagttttacccaACCATCAACACTGAGGcagcatcttttaattcatgagggcaagaagccacataagtgtgaaatttgtggcaaAAGCTTTACTCAGGCATCAACACTGCGGCGCCATTTTTTAATTCACGAGGGCAAGAAgccccataagtgtgaagtttgtgggaagagctttacccatacATCTACTTTAAGGACACATTTGTTGATTCACAAAGGTAataagccacataaatgtgaaatttgtgaaaagaacTTTACCCAGGCATCAACATTGAGgcaacatcttttaattcataaaGGCAAGAAGtcccataaatgtgaagtttgtggcaagagctttaTCCGAGCACCTGATTTGAGAGAGCATGTTTTAATTCATGAgtgcaagaagccacataagtgtgaagtttgtggaaaaagctTTACTCATGCATCTAATTTAAGAACACATTtgttgattcatgagggtaagaagccacataaatgtaaggtttgtgagaagagctttacacaGGGATCAACATTGAGAcagcatcttttaattcatgaagggAGGAAGtcccataaatgtgaaatttgtggcaacagctttacccaggcatctcGTTTGAGAGAACATCTTTGGACTCATGAGAGCatgaagccacataagtgtgaaatttgttgTAAGAGCTTTATCCGAGCATCACGTTTGAGAGAGCATCTTTTAATTCACCAGTGCAAGAAGCCCcataaatgtgaggtttgtgGAAAAAGCTTTACTCAAGCATCTACTTTGGggcaacatcttttgattcacgaggACAAGAAACTCTTTAGCTGA
Protein Sequence: MDLSNTFFRKQWSFQQDSAPVHKAKSTQDWLQRNVPDFIAMDDWPSSSPDLNPLYKLWSMLEGMVYKKSYPSINSLKRSLVKAVADFPMETVHNSIDAWPQRLRACEQELDIAVMKDKVKVEEFNIPGARKSHKCEACGKSFFKESSLRQHLLIRESKKPHKCEVCGKSFTYAYSLRIHTFIHEGTKPHKCEICGKSFTQAKTLRQHLMIHEGRKPFKCGVCEKSFTQTAHLREHLVIHECIKPHKCKVCGKSFAHPSTLRIHLLIHEGKKPHKCEVCGKSFTQPSTLRQHLLIHEGKKPHKCEICGKSFTQASTLRRHFLIHEGKKPHKCEVCGKSFTHTSTLRTHLLIHKGNKPHKCEICEKNFTQASTLRQHLLIHKGKKSHKCEVCGKSFIRAPDLREHVLIHECKKPHKCEVCGKSFTHASNLRTHLLIHEGKKPHKCKVCEKSFTQGSTLRQHLLIHEGRKSHKCEICGNSFTQASRLREHLWTHESMKPHKCEICCKSFIRASRLREHLLIHQCKKPHKCEVCGKSFTQASTLGQHLLIHEDKKLFS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00995968;
90% Identity: iTF_00995968;
80% Identity: iTF_00995968;