Mwes009409.1
Basic Information
- Insect
- Merzomyia westermanni
- Gene Symbol
- -
- Assembly
- GCA_949987695.1
- Location
- OX465288.1:195625509-195633391[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.13 22 7.3 1.2 1 23 1884 1907 1884 1907 0.93 2 12 0.7 1.2e+02 5.1 1.1 1 23 2091 2113 2091 2113 0.94 3 12 0.00032 0.054 15.6 2.5 2 23 2116 2137 2116 2137 0.97 4 12 3.1e-05 0.0052 18.8 0.2 3 23 2145 2165 2143 2165 0.98 5 12 2.8e-06 0.00047 22.1 3.7 2 23 2172 2193 2171 2193 0.97 6 12 9.5 1.6e+03 1.5 0.4 5 23 2206 2224 2204 2224 0.96 7 12 0.0089 1.5 11.0 0.3 2 23 2263 2283 2262 2283 0.96 8 12 0.00025 0.042 15.9 0.8 1 19 2289 2307 2289 2311 0.93 9 12 7e-06 0.0012 20.8 1.1 1 23 2319 2341 2319 2341 0.98 10 12 0.00018 0.03 16.4 7.6 1 23 2347 2369 2347 2370 0.96 11 12 0.0017 0.28 13.3 6.5 1 23 2375 2397 2375 2397 0.98 12 12 0.003 0.49 12.6 6.0 1 23 2403 2425 2403 2426 0.96
Sequence Information
- Coding Sequence
- ATGGGGGAAAACGTGCAGTGTCCAGTATGCACACTATTTTTGCATGCTGGCATGAACCTGTCGGACCATTTAGAGACACATCCTAAGGAACAAGTGATTAAAGCACTTGTCCAAATGACCATCACAGGCGGCATTGGTACAGCTGCAAGTAAAGCCCTTTCGGCATCCTTAAGTGGTGGCAGTGGAGGCGAGCCCAAAAAAGAATCGGACGAAAATAAGACAATTCCGCCAACAATCTCTGCCGATGCAGCTGAAGCGCCTAGTAATGCAGCATCCAAGAGTTTATCGCCTTTGGAAGCTGTTAGGAAAACCCCCACCAACAACCACACTAATAGTGCGAATGTTGCAGCCGCTTTTAGTGCTATACCAGCAATAACCAAATCATTAGCTTCAAACATAGCTTCAGCGGCAACATCATCTCCTGCGGCAGCAAAGACACTTGGCGAAATGTGTGTAAAGAACAATGTAGAACATAAACTTGATACAGCTAATGGGATTGATAACAAGATTACAGTCTCAATTGAAACAGCTGCGCAGGCACCAGCGCCACGTAGTGCCCTTGGTCAACTGGCACCAAGTACTAGGTTTGATGGTTATGCTGCGAGTGGTTATCATCAAACGCATCAAAAACAATTATCAATAAGTCAATTAGatccgcaacaacaacagaaagaaCTGCAACCACCGCCAAGCCAGCAGCAaccacagcagcagcagcagcagcaacaaaaacaaaaacagcagcATATTGAAAATGCATCTATTAGTAATGCAATAGTACAACAGCGCATTACATTGCCCCCACCTCCTCCACCAATGTTAACAATGCCGATTGTAATAGGCCAAATGCCGAATAAATTGTTACATCAAGCCCAAACAACAAATCAATTTCCAAGCAATCTGTCTACTCATCGCCACGTTCCAATGCATCCGGTTCTGCATCCAAATCAACAGCTCCAACATTTAtatcagcaacagcaacaacaaacgcaGCAAAATCACAATCAGCAAGAACATCAACAGCAGCAGAACCTCAAAATATATTATTCTGCAGCTATGCCAACACCACCACCTGGACTGCAGctATTCCCTTTCCACGCATCAGCACAAATGCAACATCAAAAACCACCGCCCGCTTATGGTACAGCGATAAGTCAAATTCGATCTcagcataaccaaaacaaaaataataacactaTAGAAAAAAGCCATATACCACATCAACAACAGTTGCACAATCAAGCACAGCGACAAAACcagcagcgacaacaacaacaacagcagcagcagcaacaacaacaacaacaacaacagcagcagcagcagcagcaacaacaccaacagcaacaacataaacaacagcagcaccaacaacagcaacataaacaacagcagcagcaccaacagaaacaacatcaactGCAACAAATCCAGCtggtccaacaacaacaacaacatcaacaggtgcaacaacaacagctgccGATCCCGCTTCATAATCAACAGCGTTCAACAATGCATTCAACGGCGCACCAACAACCTACAGCAAATGTTTCTACATCACTGCAGCAATCAAACCACAATCATAACCAACAGACCCTTGAAAATATACAACCATTGGGTGTGAAACCTCTACTTGAAGCCAAGTCGACTGAATTACTTCCACCGCCACCTCCTCCACCCACACGGACGATAAATAATTTACATCATCATCAGTTGCCACATTCGCTGTCACAGTTTGGATTACCTATTAAGTCTTTAACCCCTACACACCAACGTGGTGCAAATGCAACTGACACTAGTACTATAGCCAGTGCCACAATATCAAATCAGCACACACTACCTATCGCTACAGCAGTCAATGGCTCTGCAGGAGCTGCTACACCAGCTATTATATCTGTCGCATCTGCTGGTGGTATACGACAAGTAACTTCACCATACAATTCATTGCTATTTTCAGCAGCACAAGCACAATCATCATCCTCAGTGTTGCGCTATGCTGAATCTCCTGTGGCACATTATTTGGAACGGGACAATGGCGATTTTATTGTACAAGAAACACCCAAACACATTGTCGAATGCGTTGAGAAGGAGAATGGGGAGTTTTCGGTTATTGAACATATTTATCAGTCGCCATTAAGCGTTTTACACATACATgaggatgatgatgatgatgacgacgaCATTGCTGATGATGATAGTGGTGATGAAAGTGATATGAAGGACAACGATAAAAAGAAGTCCAACACAGCTGATGAAGAGCAAAAAAATAAAGGTGGTGAAGAGCCTATGGATCTCGAAGAATGCGCTGGAGGTTCGAAAAGTGAAGATAATGCGAACGATAAATGTGGACGTTTATCCAGAAGTTCTCCTGTAAAACATGCAGAAATTATTGAAAAGAACGCTTCCGCAGACAATGAAAAGCTACCAACAAAAattagtggtagtgatagtaaaataaaaaacgacaGGAGTATTTCTTCTGGTGGCACATCCGTAAGCTCTGCCAGTACAGATATAAGTTGTGATCCCAGTTCAACTTCAAATTCAAGTTCAAATACCATTAACGAATCTAATGTAATGTGCAGTACATCTTCAAGTTCCAACCAAAGTCCCAATCCTCACTCAGCAGCAACAGGTACATCAAGAAAACGTAGCTCTAAAAATACGATAACAGTGTTAAGCGACGTACAATTAAATTTGGATGAATACCTCGATTTGGTCGGAAATATTATAGCATCAAGTAAAATATCACCAAAAAGTAGTATGCTTTCAGGATCTATGCCTTTACCtttattaaaagttgaaaaagaaGAACCGCCCGATGACGACTACGAAATGCAGAACAAGCAACAAGACGAACAAAATACCGAAGAACAAGAAAATGAAGAATATTGCGAAAAACAGAATGAGCTTAAAGATTTCCATGCGCCAACTGTAATCGAACCACCTACAATCGCCAACATAAATGAGACTGAAAAACTAGTTGAAAATAATTGTAGTAGCAATAAAGTTAGATTAAATGATAATGAGAATGATAAAAATGCTTTGACTGATGTTATGTTGCATTTGCAAAATGccaaaaatttaatggcaatGCCAGCGAAATCCATCGCATCTCCATCAACATCCATCGCACCACCACCAGCAACCGCTACAGCAACATCAACATGTTCGAGTCATGTGACAAGTGTTATACGCATGGCAACGActagtcaacaacaacaacatcagcaatTCCAAAAGGAAATAGGACATCAACAAAGAAATGCTTCCAAAGCAAACGAAGCACAATTTAAAAATACGTATGGCGATGCAACTACATCTGCAACTGAACCGAAAATAACATCAATAATTATTCAAGACTTATCACGGCAACATATTATTCAACTACAAGAACAAGAAGAACAAACGGAAAATGTGCAGCCACAGCAGCTACTTGATGCGCAAGATGTAAGCAACTTGCCAAATACACAACAGGAGTTGGAGCCAGTAGTGCAGCTGCAGCAGTATAAACAAATGCCTCCCATGATTACACTGCCAGTGCAGAAAAAGGGGCCAAAGAAGCTGATTATCAAGCCAAAACCAAAAAAGACTGATGCAAATGAAAAcctcaacaacaacagcaataaaaatagagatataaaaattcgaaaaacccGTGAAATACAGGAAGAAGAAGGTTTAGATGAACAACCCACAACATCATCCAGAGCACAAATGGAATTGCAAGAAAAATATCAACAGCAGACTAAACAAAACGACGAGCACGTGAAACATACAATTGTAGCACATGATTTGATAAAACTGGAACCAAGCACAGCATCGTATGATTGCAATACCAACCGAGTTGGTAACAGCATTGGTCTCAGCATTCTTGGAAATCATCTGAGTGCATACAGTAAAGAAccaatttttcaatgtaaaaccgaaaaatcaacTGACCCACCAACAAACTATTTACATCCTTTAAAGGAGGAACTAAAGGAGACGAGTAATTCAAATAATGATGCAGCTGTAAATGATGACGCACGCGTTTTGCTGGATTTTGCCCACTCAAAGAAACGTACGAATCTTGCTAATTTTCTCTCTGTCAACTCAATTTTTTCCAACTCACCAAAATCATTAAATGAACCCaaaccaataacaacaacaacagcagtgacACTAACTAACATGAATACGAATAGCAATGATTCAGATGCAGGTTTACGTTGTGATGATGAATTCATAGCACACGATGAAGTGCAAGAGATTGTTATATCATCATCGTATTCACAATCTCAATCAGCATCAGATATACCAATCAATTCATCGAACAATAGCACAACATCGCAAGTTAAAGATTTAAGTATTGTGAATAAGGAGCAACACCACCAAGAAAATcaccagcagcagcagcaacagcagcaacaaaatttaaatcacAATTTTGCGGATTATCCATTTAGTTTCCTATATGGAAATAGTGGTGCAACAGGTGGTGGCGGCAGTACACAACAAATAGATGCCAAAAGTGGTAATTTCTCTGCAATATATCAGCAGGAGGCAGCACAGGATGCTACTACAGCAGCAACACTGGCATCTGGGAGTAATACAGTGCATACCGACGAGTCCACCAGTTCGACCCAGCAGCAGCAGCGGCGATCCCATGTCAGCACTAATCACTTTGGCGATGTACACGCTGCTAGCGGTGTACTAGGCGGCAATGCATCACATTGGTATCATCATGCATTGGCAACAGCAAATGCTGATTTTGAAACAGCATTGGCAGTGGACTGCAGTGCAGCGATTGATAGTGGTGAAGTGGGTAAATATTTGGATTTGGATACTTGTAAACGTGAGGCTCTAGTCGGTATGCCAGCTGCACACTCTTCGACTTCATCGTCTTTTGCTGTAGCCACAGATAGCAGTTTGGCTGGAGGTAGTACAGCTGATGCACTAAATATACGTACAGATGAGAAGATGCCGGCGAAAGGTGAAATATCAGGACAGGAAAGTAATTGCGATATTGAAAATTCGTGGAGTCAGCCGATGTATGGTGAAATTTCGGCACGATTTTTCAAAACTACTTTTCCCGGCATATTTCACCAAGAAAATGGTTGGAACCAGGACGAGTACTTCACAGTACAGGATTTGAGCGCCTCAGCTGCTGCAGCAGGCAATGCGACCGCTTCTAACCGTACCGGCGGCAAAAGctTTGATTTCCGCCTTCCTTTGGAAACAACTACCTCAGCTGCAGCGAATGCCATTGGTAATGGAAATGGTAATTTCCAACTGTTTGCTCGGCATGCAGATGCATTACCATCGTCATCCATTTCGAATAAAAAGAAACGTAAACGCGACAATTCCGGTAGTAGTGATACTAATATTGTTGGTCGAATTGGAAAAGCGACACCATCACGCATTCAACCAACGTCCACAATAACGTCACAACAACTTGTGTTtaatcaacagcaacaacagcagaaCAGTCAACATCAGCAACAGTTACAGGCACATCCACAATTGCAAGATATCAGCATGAATGCTGCAACTTCCACAGCAGCATTTAACACGAGTGGTACTACGGCTTCAATAGCTGCTACTGATGCTGACAACGCCGATACTTTGTTAATTGTGGATCAGAGGCGACAACGCAAGAAAGTTTATCAATGTACACATTGCACAGCTGAATTTCCAAAACTTAAAGATCGTAATTCGCATATGGTACTGGAACATAATTATGTGCGTCAAAATAGACGATTGATATGTGTTCAGCGCCCGGGTGCTGGCTCAGCTGCTGCTGCGCCTTCATCATCGTTATCATCAAATACAAATGCCCCCGTCGGTAGTGCAAATAATGCGATGCTCTTAAATATGACTGATGGTTATAACAACACTCTCGTACGGACAGATGCTATGGAATTAATGGAGGACTCAAAGCATgatattattaaaattgaggTAGAAAATGTATATCAACCGACAGCTGGTTCAACGCTTGAGGCAGGCGCGGCGGTTGGTattcaagccaagaaagaattAACGGATAACAAACAGGGCATAGCACTAATGCCTGCAGGAAGTTCAAatgcaaataatgaaaatgctGATAGTGTCACTGATGTGGTGGATACAAAAGCCAGACATATTCTACCACTAGGAATGACAACACCAGCAACAAAATTAGCTGCACTCTATCGTATGTTGGTATCGTACAATATTTCAACACTTAAAGATAACCACAATCTAAGTGAACTGGAACAGAAACTCATTGAACAatcgatatttttttgttatgtgtGTCGTCGTAATTTCACATCGGTAAAATTATATGATGCACATTTGAGTGAGCATCCCGCTGAATGTTTTACGTGCGGCAAAACGTTTCAGCGttggaaaaatttttcattgcatTTGAAACGTCATTTGGGATGGAAAGAGTTTGGTTGTAATGTGTGCGACAAAAAGTTTGTGGTGCGCAGCGCACTGGTGGAACACATGCGCATGCATACTGGGCATACACCACTCAAGTGTAAAATATGTGGCAAGTACTTTAAACGCTACTCGAATTTAACGCAGCATCGCAAACGTCATGGTAAGAAGATCATACGAAAGAAAGAATATGTTTGTCATTGTGGTGAAGTTTTGCCATCTAAAGCGCGTTTCCTGTGGCATAAGGAAACACACGATGCTAAACCGAAATGTTGCCCCCATTGTTGTGATCGTTTTGTACATGCAAATTCATTGCGTCGTCACATACGATTAGCGCATTCCGATAAATTCGACTACACCGAACCGATGGAGTGTCCTTTATGTAAGCAAACTTTTGCTAAATCCTCCATGAAAGCGCACATGGCCACACATTCAATGGACACACAACATGATTGCGCTATATGCAATAAATCATTTTCCACAAAATGGAATCTAAAAATACATTCTTGGGTGCATGCTAATCGTACCGCTAAACCATACAAATGCGAACACTGCCCAAAAGCGTTTGTGCGTGAAGTTGATTTTAAGAATCACATGAATGCACATAAACAAATCAAACCATATACATGCGAATATTGTGGTTgtaaatttattagaaaatataattatatgcGTCATCGACGTGAACATCAtggtaataaaaaatttacctgTGACCTGTGTAAAAAGTCCTTCCATCGGCATTATTATCTCATCGAGCATAGACGCATACATACAGGCGAAAGACCATTTCAATGTACCATATGCGGCAAAAGTTCCACAACGAAAACAAATCATaataaacatttgaaaatacatCATTCGCGTGATCCCTTCACCGTAGAGGCGTAA
- Protein Sequence
- MGENVQCPVCTLFLHAGMNLSDHLETHPKEQVIKALVQMTITGGIGTAASKALSASLSGGSGGEPKKESDENKTIPPTISADAAEAPSNAASKSLSPLEAVRKTPTNNHTNSANVAAAFSAIPAITKSLASNIASAATSSPAAAKTLGEMCVKNNVEHKLDTANGIDNKITVSIETAAQAPAPRSALGQLAPSTRFDGYAASGYHQTHQKQLSISQLDPQQQQKELQPPPSQQQPQQQQQQQQKQKQQHIENASISNAIVQQRITLPPPPPPMLTMPIVIGQMPNKLLHQAQTTNQFPSNLSTHRHVPMHPVLHPNQQLQHLYQQQQQQTQQNHNQQEHQQQQNLKIYYSAAMPTPPPGLQLFPFHASAQMQHQKPPPAYGTAISQIRSQHNQNKNNNTIEKSHIPHQQQLHNQAQRQNQQRQQQQQQQQQQQQQQQQQQQQQQQHQQQQHKQQQHQQQQHKQQQQHQQKQHQLQQIQLVQQQQQHQQVQQQQLPIPLHNQQRSTMHSTAHQQPTANVSTSLQQSNHNHNQQTLENIQPLGVKPLLEAKSTELLPPPPPPPTRTINNLHHHQLPHSLSQFGLPIKSLTPTHQRGANATDTSTIASATISNQHTLPIATAVNGSAGAATPAIISVASAGGIRQVTSPYNSLLFSAAQAQSSSSVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKENGEFSVIEHIYQSPLSVLHIHEDDDDDDDDIADDDSGDESDMKDNDKKKSNTADEEQKNKGGEEPMDLEECAGGSKSEDNANDKCGRLSRSSPVKHAEIIEKNASADNEKLPTKISGSDSKIKNDRSISSGGTSVSSASTDISCDPSSTSNSSSNTINESNVMCSTSSSSNQSPNPHSAATGTSRKRSSKNTITVLSDVQLNLDEYLDLVGNIIASSKISPKSSMLSGSMPLPLLKVEKEEPPDDDYEMQNKQQDEQNTEEQENEEYCEKQNELKDFHAPTVIEPPTIANINETEKLVENNCSSNKVRLNDNENDKNALTDVMLHLQNAKNLMAMPAKSIASPSTSIAPPPATATATSTCSSHVTSVIRMATTSQQQQHQQFQKEIGHQQRNASKANEAQFKNTYGDATTSATEPKITSIIIQDLSRQHIIQLQEQEEQTENVQPQQLLDAQDVSNLPNTQQELEPVVQLQQYKQMPPMITLPVQKKGPKKLIIKPKPKKTDANENLNNNSNKNRDIKIRKTREIQEEEGLDEQPTTSSRAQMELQEKYQQQTKQNDEHVKHTIVAHDLIKLEPSTASYDCNTNRVGNSIGLSILGNHLSAYSKEPIFQCKTEKSTDPPTNYLHPLKEELKETSNSNNDAAVNDDARVLLDFAHSKKRTNLANFLSVNSIFSNSPKSLNEPKPITTTTAVTLTNMNTNSNDSDAGLRCDDEFIAHDEVQEIVISSSYSQSQSASDIPINSSNNSTTSQVKDLSIVNKEQHHQENHQQQQQQQQQNLNHNFADYPFSFLYGNSGATGGGGSTQQIDAKSGNFSAIYQQEAAQDATTAATLASGSNTVHTDESTSSTQQQQRRSHVSTNHFGDVHAASGVLGGNASHWYHHALATANADFETALAVDCSAAIDSGEVGKYLDLDTCKREALVGMPAAHSSTSSSFAVATDSSLAGGSTADALNIRTDEKMPAKGEISGQESNCDIENSWSQPMYGEISARFFKTTFPGIFHQENGWNQDEYFTVQDLSASAAAAGNATASNRTGGKSFDFRLPLETTTSAAANAIGNGNGNFQLFARHADALPSSSISNKKKRKRDNSGSSDTNIVGRIGKATPSRIQPTSTITSQQLVFNQQQQQQNSQHQQQLQAHPQLQDISMNAATSTAAFNTSGTTASIAATDADNADTLLIVDQRRQRKKVYQCTHCTAEFPKLKDRNSHMVLEHNYVRQNRRLICVQRPGAGSAAAAPSSSLSSNTNAPVGSANNAMLLNMTDGYNNTLVRTDAMELMEDSKHDIIKIEVENVYQPTAGSTLEAGAAVGIQAKKELTDNKQGIALMPAGSSNANNENADSVTDVVDTKARHILPLGMTTPATKLAALYRMLVSYNISTLKDNHNLSELEQKLIEQSIFFCYVCRRNFTSVKLYDAHLSEHPAECFTCGKTFQRWKNFSLHLKRHLGWKEFGCNVCDKKFVVRSALVEHMRMHTGHTPLKCKICGKYFKRYSNLTQHRKRHGKKIIRKKEYVCHCGEVLPSKARFLWHKETHDAKPKCCPHCCDRFVHANSLRRHIRLAHSDKFDYTEPMECPLCKQTFAKSSMKAHMATHSMDTQHDCAICNKSFSTKWNLKIHSWVHANRTAKPYKCEHCPKAFVREVDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDLCKKSFHRHYYLIEHRRIHTGERPFQCTICGKSSTTKTNHNKHLKIHHSRDPFTVEA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01358306;
- 90% Identity
- -
- 80% Identity
- -